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Search Results: 1 - 10 of 6900 matches for " Karen Harrison "
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Legal and Ethical issues when using Antiandrogenic Pharmacotherapy with Sex Offenders
Karen Harrison
Sexual Offender Treatment , 2008,
Abstract: The treatment of sex offenders and more specifically the treatment of high-risk sex offenders is a subject of great importance for practitioners, professionals, policymakers and the public at large. Whilst treatment is thought to largely centre upon cognitive-behavioural methods and other psychotherapy techniques, in more recent years the use of pharmacotherapy has also begun to gain ground. Current debate often centres upon how effective such treatment is; with both supporters and opponents of its use existing. This article, however, does not specifically look at whether pharmacotherapy as a method of treatment with sex offenders actually works, but rather looks at the legal and ethical issues surrounding its use. In particular it considers issues such as whether the treatment should be voluntary or mandatory; whether it should indeed even be classified as treatment or should instead be seen as punishment and finally whether it should be used with convicted offenders or made freely available to all.
Legal Aspects of Surgical Castration
Karen Harrison
Sexual Offender Treatment , 2010,
Abstract: The use of surgical castration, whilst still legal in some European countries is now being practised only on a very small scale. This is largely due to the fact that many people have objections to the practice of surgically castrating offenders, especially if it is done against the offender's will. Even if consent is given there may be problems regarding whether this consent is truly free and informed (see below). Many regard the practice as barbaric and thus in contravention of a number of Articles contained within the European Convention of Human Rights (ECHR), including Article 3, Article 8 and Article 12. These issues will be addressed below.
Pharmacotherapy and Human Rights in Sexual Offenders: best of friends or unlikely bedfellows?
Bernadette Rainey,Karen Harrison
Sexual Offender Treatment , 2008,
Abstract: The use of pharmacotherapy is gaining ground as a risk treatment and/or risk management option with sex offenders, around the world. Whilst several articles have recently been published which look at the efficacy of this option, this is not the focus here. Rather it assesses the human rights implications of its use and importantly, questions whether the use of sexual suppressants with or without consent is a viable option in light of obligations under International Human Rights Law. With particular reference to the European Convention on Human Rights and the concept of human dignity, it examines whether pharmacotherapy is being administered in line with human rights protection.
Three Hours a Day: Understanding Current Teen Practices of Smartphone Application Use
Frank Bentley,Karen Church,Beverly Harrison,Kent Lyons,Matthew Rafalow
Computer Science , 2015,
Abstract: Teens are using mobile devices for an increasing number of activities. Smartphones and a variety of mobile apps for communication, entertainment, and productivity have become an integral part of their lives. This mobile phone use has evolved rapidly as technology has changed and thus studies from even 2 or 3 years ago may not reflect new patterns and practices as smartphones have become more sophisticated. In order to understand current teen's practices around smartphone use, we conducted a two week, mixed-methods study with 14 diverse teens. Through voicemail diaries, interviews, and real world usage data from a logging application installed on their smartphones, we developed an understanding of the types of apps used by teens, when they use these apps, and their reasons for using specific apps in particular situations. We found that the teens in our study used their smartphones for an average of almost 3 hours per day and that two-thirds of all app use involved interacting with an average of almost 10 distinct communications applications. From our study data, we highlight key implications for the design of future mobile apps or services, specifically new social and communications-related applications that allow teens to maintain desired levels of privacy and permanence on the content that they share.
Predictors of risky alcohol consumption in schoolchildren and their implications for preventing alcohol-related harm
Mark A Bellis, Karen Hughes, Michela Morleo, Karen Tocque, Sara Hughes, Tony Allen, Dominic Harrison, Eduardo Fe-Rodriguez
Substance Abuse Treatment, Prevention, and Policy , 2007, DOI: 10.1186/1747-597x-2-15
Abstract: Of all respondents, 87.9% drank alcohol. Of drinkers, 38.0% usually binged when drinking, 24.4% were frequent drinkers and 49.8% drank in public spaces. Binge, frequent and public drinking were strongly related to expendable income and to individuals buying their own alcohol. Obtaining alcohol from friends, older siblings and adults outside shops were also predictors of risky drinking amongst drinkers. However, being bought alcohol by parents was associated with both lower bingeing and drinking in public places. Membership of youth groups/teams was in general protective despite some association with bingeing.Although previous studies have examined predictors of risky drinking, our analyses of access to alcohol and youth income have highlighted eradicating underage alcohol sales and increased understanding of children's spending as key considerations in reducing risky alcohol use. Parental provision of alcohol to children in a family environment may also be important in establishing child-parent dialogues on alcohol and moderating youth consumption. However, this will require supporting parents to ensure they develop only moderate drinking behaviours in their children and only when appropriate.In recent years increasing levels of hazardous and harmful alcohol use, along with their negative health consequences, have received international attention as issues requiring immediate action. Thus, the World Health Organization (WHO) has identified excessive alcohol use as one of the most important risks to health [1] and the World Health Assembly (Resolution WHA58.26) has requested Member States to implement effective interventions to tackle alcohol misuse [2,3]. Within the WHO European Region, where per capita alcohol consumption and related disease burden are double global averages [4,5], two successive alcohol action plans (covering 1992 to 2005) have been followed by a Regional Framework providing strategic guidance to member states on the development and implementation
Physical function assessment tools in pediatric rheumatology
Lakshmi Moorthy, Margaret GE Peterson, Melanie J Harrison, Karen B Onel, Thomas JA Lehman
Pediatric Rheumatology , 2008, DOI: 10.1186/1546-0096-6-9
Abstract: Pediatric rheumatic diseases causing arthritis, fatigue, muscle weakness and blindness are associated with significant functional impairment. For several children with rheumatic illness, physical functional ability is often the chief determinant of their well-being. Quality of life (QOL), health-related QOL (HRQOL), physical function and health status scales are all used as outcome measures in children with significant musculoskeletal involvement, and account for varying degrees of patient-perceived state of physical ability/and or impact of physical disability on overall well being.The World Health Organization QOL group defined QOL as "individuals' perceptions of their position in life in the context of the culture and value systems in which they live and in relation to their goals, expectations, standards and concerns. It is a broad ranging concept affected in a complex way by the person's physical health, psychological state, level of independence, social relationships, and their relationships to salient features of their environment" [1]. Calman et al has presented a "goal-oriented" model where QOL measures the difference between a person's expectations and current position at a certain time[2]. Recent scientific advances have increased life span, often at the expense of increased medication use and commensurate drug-related complications, more frequent medical visits and evaluation, all of which can lead to significant emotional and lifestyle changes. QOL emerges as a critical issue in this regard and becomes a primary consideration for the improvement in modern medicine.Specifically for patients with chronic diseases, health primarily impacts the overall QOL. HRQOL is defined as "optimum levels of mental, physical, role and social functioning, including relationships, and perceptions of health, fitness, life satisfaction and well-being" [3]. Implicit in HRQOL is the "assessment of patient's satisfaction with treatment, outcome and health status and with futur
Adolescent health screening practices by physicians in Jamaica
Harrison,Abigail; Pierre,Russell; Gordon-Strachan,Georgiana; Campbell-Forrester,Sheila; Leslie,Karen;
Revista Panamericana de Salud Pública , 2011, DOI: 10.1590/S1020-49892011000400006
Abstract: objective: to review jamaican physicians' adolescent health screening practices by determining their frequency in areas of biomedical, psychological, social, and educational health; the factors that influence these practices; and physicians' perceived level of self-efficacy and their awareness of screening tools and guidelines. methods: a questionnaire was mailed to general practitioners, family medicine specialists, and pediatricians in jamaica. the primary outcome variable was the frequency of physician screening for a range of biomedical, psychosocial, and educational developmental issues in the majority (> 50%) of adolescent patients. bivariate analyses were performed to determine differences between professional groups. results: the response rate was 32.3% (n = 213), with 209 responders being suitable for further analysis. the sample comprised 48.8% general practitioners, 33.0% family medicine specialists, and 18.2% pediatricians. physicians more often screened for biomedical risks than for psychosocial risks, with very low frequencies of screening for psychosocial issues such as mood, suicidal ideation, sexual orientation, and safety concerns. physicians reported high levels of confidence in discussing most psychosocial issues with adolescent patients. time limitation and an insufficient knowledge base were the main factors identified as influencing screening practices. conclusions: the data suggest unsatisfactory frequency of adolescent health screening by jamaican physicians, in particular for psychosocial factors. the primary factors identified by physicians as influencing their screening practices have potential for improvement through continued medical education.
The Asthma Consultative Process: A Collaborative Approach to Integrating Genomics Into Public Health Practice
Karen L. Edwards, PhD,Tabitha A. Harrison, MPH,Wylie Burke, MD, PhD
Preventing Chronic Disease , 2005,
Abstract: Genomics research findings on asthma are reported with increasing frequency. As these findings are incorporated into existing knowledge of disease etiology and pathogenesis, the implications for public health practice need to be considered. In 2003, the University of Washington Center for Genomics and Public Health initiated a project to synthesize information about asthma genomics, to examine its relevance to public health research and practice, and to communicate findings to a public health practice audience. This goal was achieved through review of the scientific literature, formation of a working group, and consultations with professionals and community organizations. This paper describes the methods used to conduct these professional and community consultations, referred to as the asthma consultative process, and discusses the lessons learned from this activity.
Sound Frequency Discrimination in Normal-Hearing Listeners and Cochlear Implantees
Evan J. Propst,Karen A. Gordon,Robert V. Harrison,Sharon M. Abel
University of Toronto Medical Journal , 2002, DOI: 10.5015/utmj.v79i2.888
Abstract:
Sheep Monoclonal Antibodies Prevent Systemic Effects of Botulinum Neurotoxin A1
Jean Mukherjee,Chase McCann,Kwasi Ofori,Julia Hill,Karen Baldwin,Charles B. Shoemaker,Peter Harrison,Saul Tzipori
Toxins , 2012, DOI: 10.3390/toxins4121565
Abstract: Botulinum neurotoxin (BoNT) is responsible for causing botulism, a potentially fatal disease characterized by paralysis of skeletal muscle. Existing specific treatments include polyclonal antisera derived from immunized humans or horses. Both preparations have similar drawbacks, including limited supply, risk of adverse effects and batch to batch variation. Here, we describe a panel of six highly protective sheep monoclonal antibodies (SMAbs) derived from sheep immunized with BoNT/A1 toxoid (SMAbs 2G11, 4F7) or BoNT/A1 heavy chain C-terminus (HcC) (SMAbs 1G4, 5E2, 5F7, 16F9) with or without subsequent challenge immunization with BoNT/A1 toxin. Although each SMAb bound BoNT/A1 toxin, differences in specificity for native and recombinant constituents of BoNT/A1 were observed. Structural differences were suggested by pI (5E2 = 8.2; 2G11 = 7.1; 4F7 = 8.8; 1G4 = 7.4; 5F7 = 8.0; 16F9 = 5.1). SMAb protective efficacy vs. 10,000 LD50 BoNT/A1 was evaluated using the mouse lethality assay. Although not protective alone, divalent and trivalent combinations of SMabs, IG4, 5F7 and/or 16F9 were highly protective. Divalent combinations containing 0.5–4 μg/SMAb (1–8 μg total SMAb) were 100% protective against death with only mild signs of botulism observed; relative efficacy of each combination was 1G4 + 5F7 > 1G4 + 16F9 >> 5F7 + 16F9. The trivalent combination of 1G4 + 5F7 + 16F9 at 0.25 μg/SMAb (0.75 μg total SMAb) was 100% protective against clinical signs and death. These results reflect levels of protective potency not reported previously.
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