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Search Results: 1 - 10 of 51363 matches for " Kaneko Y "
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Eelectrical Transport Properties of C59N Azafullerene Encapsulated Double-Walled Carbon Nanotube  [PDF]
Y. F. Li, T. Kaneko, R. Hatakeyama
Open Journal of Microphysics (OJM) , 2011, DOI: 10.4236/ojm.2011.12004
Abstract: Electrical transport properties of double-walled carbon nanotubes (DWNTs) are modulated by encapsulating the azafullerene C59N which is synthesized via a plasma ion-irradiation method. The encapsulation of C59N molecules inside DWNTs has been confirmed by both transmission electron microscopy and Raman spectroscopy. The pristine DWNTs with outer diameter 4 - 5 nm are found to exhibit an ambipolar semiconducting behavior due to their small band gap. It is found that C60 fullerene encapsulated DWNTs exhibit a unipolar p-type semiconducting behavior. By comparison, C59N encapsulated DWNTs display an n-type semiconducting behavior. Our findings demonstrate that C59N operates as an electron donor compared with the acceptor behavior of C60, which is further clarified by photoelectron emission spectroscopy.
Stainability and Fine Structure of Intracytoplasmic Inclusion Bodies in the Locus Ceruleus of Mouse  [PDF]
Yoshimitsu Y. Katoh, Kazuyoshi Sakai, Chiyuki Kaneko, Masato Abe
Journal of Behavioral and Brain Science (JBBS) , 2013, DOI: 10.4236/jbbs.2013.37058
Abstract: The present study compared intracytoplasmic inclusion bodies in the locus ceruleus (LC) of mouse with protein bodies in the LC of human. Phosphotungstic acid-hematoxylin (PTAH) and the Mallory method were used as the anionic stains. The inclusion bodies and protein bodies, which stained with PTAH and the Mallory method in the brain, contain proteins that appear to belong to the same family. Although both inclusion and protein bodies were formed with the same arginine composition, their distribution in the brain was similar and similar physiological changes by morbidity were observed, and the fine structure of the inclusion bodies and protein bodies appeared to be different. The present findings suggest that mouse inclusion bodies and human protein bodies are different.
Functional coating of liposomes using a folate–polymer conjugate to target folate receptors
Watanabe K, Kaneko M, Maitani Y
International Journal of Nanomedicine , 2012, DOI: http://dx.doi.org/10.2147/IJN.S32853
Abstract: nctional coating of liposomes using a folate–polymer conjugate to target folate receptors Original Research (2483) Total Article Views Authors: Watanabe K, Kaneko M, Maitani Y Published Date July 2012 Volume 2012:7 Pages 3679 - 3688 DOI: http://dx.doi.org/10.2147/IJN.S32853 Received: 11 April 2012 Accepted: 14 May 2012 Published: 13 July 2012 Kazuo Watanabe, Makoto Kaneko, Yoshie Maitani Institute of Medical Chemistry, Hoshi University, Tokyo, Japan Abstract: Folate-polymer-coated liposomes were developed for targeted chemotherapy using doxorubicin (DXR) as a model drug. Folate-poly(L-lysine) (F–PLL) conjugates with a folate modification degree of 16.7 mol% on epsilon amino groups of PLL were synthesized. DXR-loaded anionic liposomes were coated with F–PLL, and the cellular association of F–PLL-coated liposomes was evaluated by flow cytometry, and confocal microscopy in human nasopharyngeal carcinoma KB cells overexpressing folate receptors (FRs), and human lung adenocarcinoma A549 cells [FR (-)]. The existence of a polymer layer on the surface of F–PLL-coated liposomes was confirmed by zeta potential analysis. The KB cellular association of F–PLL-coated liposomal DXR was increased compared with that of PLL-coated liposomes and was inhibited in the presence of free folic acid. Twofold higher cytotoxicity of F–PLL-coated liposomal DXR was observed compared with that of the PLL-coated liposomal DXR in KB cells, but not in A549 cells, suggesting the presence of FR-mediated endocytosis. These results indicated that folate-targeted liposomes were prepared successfully by coating the folate–polymer conjugate F–PLL. This novel preparation method of folate-targeted liposomes is expected to provide a powerful tool for the development of a folate-targeting drug nanodevice as coating with ligand–polymer conjugates can be applicable to many kinds of particles, as well as to lipid-based particles.
Hall effect of spin-chirality origin in a triangular-lattice helimagnet Fe1.3Sb
Y. Shiomi,M. Mochizuki,Y. Kaneko,Y. Tokura
Physics , 2011, DOI: 10.1103/PhysRevLett.108.056601
Abstract: We report on a topological Hall effect possibly induced by scalar spin chirality in a quasi-two- dimensional helimagnet Fe$_{1+x}$Sb. In the low-temperature region where the spins on interstitial- Fe (concentration $x=0.3$) intervening the $120^\circ$ spin-ordered triangular planes tend to freeze, a non-trivial component of Hall resistivity with opposite sign of the conventional anomalous Hall term is observed under magnetic field applied perpendicular to the triangular-lattice plane. The observed unconventional Hall effect is ascribed to the scalar spin chirality arising from the heptamer spin-clusters around the interstitial-Fe sites, which can be induced by the spin modulation by the Dzyaloshinsky-Moriya interaction.
Exploring New Socio-Economic Thoughts for a Small and Narrow Earth  [PDF]
Mamoru Kaneko
Advances in Applied Sociology (AASoci) , 2018, DOI: 10.4236/aasoci.2018.85024
Abstract: The earth has been getting smaller and narrower with the expansion of human activities. Now, it is an urgent task for social scientists to explore and study new socio-economic thoughts for this small and narrow earth. This article provides a normative theory and a descriptive theory for the present and future earth. The former is to provide, viewing the earth and human community as unity, evaluations of possible events and of designs of social institutions. The normative theory helps us think about where we should direct the earth. The latter discusses social sciences for practical management of the earth. Since, however, great diversity of cultures will remain, a unified management of the earth is practically impossible. We are required to rethink and develop new socio-economic thoughts in radical manners.
The search for common pathways underlying asthma and COPD
Kaneko Y,Yatagai Y,Yamada H,Iijima H
International Journal of COPD , 2013,
Abstract: Yoshiko Kaneko, Yohei Yatagai, Hideyasu Yamada, Hiroki Iijima, Hironori Masuko, Tohru Sakamoto, Nobuyuki HizawaDepartment of Pulmonary Medicine, Faculty of Medicine, University of Tsukuba, Tsukuba, JapanAbstract: Recently, several genes and genetic loci associated with both asthma and chronic obstructive pulmonary disease (COPD) have been described as common susceptibility factors for the two diseases. In complex diseases such as asthma and COPD, a large number of molecular and cellular components may interact through complex networks involving gene–gene and gene–environment interactions. We sought to understand the functional and regulatory pathways that play central roles in the pathobiology of asthma and COPD and to understand the overlap between these pathways. We searched the PubMed database up to September 2012 to identify genes found to be associated with asthma, COPD, tuberculosis, or essential hypertension in at least two independent reports of candidate-gene associations or in genome-wide studies. To learn how the identified genes interact with each other and other cellular proteins, we conducted pathway-based analysis using Ingenuity Pathway Analysis software. We identified 108 genes and 58 genes that were significantly associated with asthma and COPD in at least two independent studies, respectively. These susceptibility genes were grouped into networks based on functional annotation: 12 (for asthma) and eleven (for COPD) networks were identified. Analysis of the networks for overlap between the two diseases revealed that the networks form a single complex network with 229 overlapping molecules. These overlapping molecules are significantly involved in canonical pathways including the “aryl hydrocarbon receptor signaling,” “role of cytokines in mediating communication between immune cells,” “glucocorticoid receptor signaling,” and “IL-12 signaling and production in macrophages” pathways. The Jaccard similarity index for the comparison between asthma and COPD was 0.81 for the network-level comparison, and the odds ratio was 3.62 (P < 0.0001) for the asthma/COPD pair in comparison with the tuberculosis/ essential hypertension pair. In conclusion, although the identification of asthma and COPD networks is still far from complete, these networks may be used as frameworks for integrating other genome-scale information including expression profiling and phenotypic analysis. Network overlap between asthma and COPD may indicate significant overlap between the pathobiology of these two diseases, which are thought to be genetically related.Keywords: C
Perovskite Manganites Hosting Versatile Multiferroic Phases with Symmetric and Antisymmetric Exchange Strictions
S. Ishiwata,Y. Kaneko,Y. Tokunaga,Y. Taguchi,T. Arima,Y. Tokura
Physics , 2009, DOI: 10.1103/PhysRevB.81.100411
Abstract: Complete magnetoelectric (ME) phase diagrams of orthorhombic $R$MnO$_{3}$ with and without magnetic moments on the $R$ ions have been established. Three kinds of multiferroic ground states, the $ab$-cycloidal, the $bc$-cycloidal, and the collinear $E$-type phases, have been identified by the distinct ME responses. The electric polarization of the $E$-type phase dominated by the symmetric spin exchange ($bm{S}_{i} cdot bm{S}_{j}$) is more than 10 times as large as that of the $bc$-cycloidal phase dominated by the antisymmetric one ($bm{S}_{i} times bm{S}_{j}$), and the ME response is enhanced near the bicritical phase boundary between these multiferroic phases of different origins. These findings will provide an important clue for the development of the magnetically induced multiferroics.
Electromagnons in the multiferroic state of perovskite manganites with symmetric-exchange striction
Y. Takahashi,S. Ishiwata,S. Miyahara,Y. Kaneko,N. Furukawa,Y. Taguchi,R. Shimano,Y. Tokura
Physics , 2010, DOI: 10.1103/PhysRevB.81.100413
Abstract: We have investigated electrically-active magnetic excitations (electromagnons) in perovskite manganites with the $E$-type (up-up-down-down) spin structure by terahertz spectroscopy. Eu$_{1-x}$Y$_x$MnO$_3$ (0.1$\le x\le$1) and Y$_{1-y}$Lu$_y$MnO$_3$ (0$\le y\le$1) without magnetic $f$-moments, which host collinear sinusoidal, $A$-type, cycloidal, and $E$-type spin orders, are used to examine the systematics of possible electromagnons. Three-peak structures (23, 35, 45 cm$^{-1}$) of magnetic origin show up in the $E$-type phase with little composition ($y$) dependence of frequencies, making a contrast with the electromagnons observed in the cycloidal-spin ($x\le0.8$) phases. One of these electromagnon is ascribed to the zone-edge magnon mode based on the calculated magnon dispersions.
Pseudogap-related charge dynamics in layered-nickelate R2-xSrxNiO4 (x sim 1)
M. Uchida,Y. Yamasaki,Y. Kaneko,K. Ishizaka,J. Okamoto,H. Nakao,Y. Murakami,Y. Tokura
Physics , 2012, DOI: 10.1103/PhysRevB.86.165126
Abstract: Charge dynamics and its critical behavior are investigated near the metal-insulator transition of layered-nickelate R2-xSrxNiO4 (R=Nd, Eu). The polarized x-ray absorption spectroscopy experiment clearly shows the multi-orbital nature which enables the x2-y2-orbital-based checkerboard-type charge ordering or correlation to persist up to the critical doping region (x sim 1). In the barely metallic region proximate to the charge-ordered insulating phase, the nominal carrier density estimated from the Hall coefficient markedly decreases in accord with development of the pseudogap structure in the optical conductivity spectrum, while the effective mass is least enhanced. The present findings combined with the results of recent angle-resolved photoemission spectroscopy show that the pseudogap in the metal-insulator critical state evolves due to the checkerboard-type charge correlation to extinguish the coherent-motion carriers in a characteristic momentum (k)-dependent manner with lowering temperature.
Impulse Turbine with Self-pitch-controlled Guide Vanes for Wave Power Conversion (Effect of Guide Vane Geometry on the Performance)
M. Takao,Y. Kinoue,T. Setoguchi,T. Obayashi,K. Kaneko
International Journal of Rotating Machinery , 2000, DOI: 10.1155/s1023621x00000336
Abstract: An impulse turbine with self-pitch-controlled guide vanes has been developed specially for wave energy conversion by the authors. Based on that work, a large turbine of 1 m diameter has been fabricated and operated on the west coast of India. In a practical turbine system, the guide vanes need substantial supports in order to heighten the strength. Such supports affect the performance of the turbine. In this paper, the etfect of guide vane support geometry on starting and running characteristics of the turbine was investigated experimentally. Two types of cross sections of support were studied, that is, circular type and airfoil type. The effect of support length was also studied.
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