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Search Results: 1 - 10 of 198216 matches for " Kailey N "
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Generalized Second-Order Mixed Symmetric Duality in Nondifferentiable Mathematical Programming
Ravi P. Agarwal,Izhar Ahmad,S. K. Gupta,N. Kailey
Abstract and Applied Analysis , 2011, DOI: 10.1155/2011/103597
Abstract: This paper is concerned with a pair of second-order mixed symmetric dual programs involving nondifferentiable functions. Weak, strong, and converse duality theorems are proved for aforementioned pair using the notion of second-order -convexity/pseudoconvexity assumptions.
Duality in nondifferentiable minimax fractional programming with B-(p, r)-invexity
Ahmad Izhar,Gupta SK,Kailey N,Agarwal Ravi
Journal of Inequalities and Applications , 2011,
Abstract: In this article, we are concerned with a nondifferentiable minimax fractional programming problem. We derive the sufficient condition for an optimal solution to the problem and then establish weak, strong, and strict converse duality theorems for the problem and its dual problem under B-(p, r)-invexity assumptions. Examples are given to show that B-(p, r)-invex functions are generalization of (p, r)-invex and convex functions AMS Subject Classification: 90C32; 90C46; 49J35.
Hybrid fixation in rotating platform mobile bearing total knee arthroplasty using low contact stress knee
Maini P,Kailey P,Talwar Naveen
Indian Journal of Orthopaedics , 2006,
Abstract: Background : Mobile bearings in total knee arthroplasty reduce wear of polyethelene and mechanical loosening of components. Method : Non-cemented Low Contact Stress (LCS) femoral implant and cemented LCS rotating platform tibial tray and polyethylene insert was used in 100 knees. Pre-operative diagnosis was osteoarthritis (OA) in 85 and rheumatoid arthritis (RA) in 15 knees. Results : Ninetyeight knees were available for follow-up at a mean interval of 38 months. Minimum of 90° flexion was achieved in all the cases. All patients were females with a mean age of 67 years. Non progressive radiolucent lines of 1-2mm were seen in 6 femoral components. Twelve tibial components also showed similar radiolucent lines in 2 or less zones. Knee Society Knee Score improved from 32 to 93 and function score from 47 to 79. Results were good to excellent in 95 knees. There was no case for bearing spin out or revision. Conclusion : Results of this study suggest that the hybrid fixation can reliably provide excellent or good results in selected patients. Key-words: Mobile bearing knee; Arthroplasty; Porocoat; Hybrid.
A Novel Intergenic ETnII-β Insertion Mutation Causes Multiple Malformations in Polypodia Mice
Jessica A. Lehoczky,Peedikayil E. Thomas,Kevin M. Patrie,Kailey M. Owens,Lisa M. Villarreal,Kenneth Galbraith,Joe Washburn,Craig N. Johnson,Bryant Gavino,Alexander D. Borowsky,Kathleen J. Millen,Paul Wakenight,William Law,Margaret L. Van Keuren,Galina Gavrilina,Elizabeth D. Hughes,Thomas L. Saunders,Lesil Brihn,Joseph H. Nadeau,Jeffrey W. Innis
PLOS Genetics , 2013, DOI: 10.1371/journal.pgen.1003967
Abstract: Mouse early transposon insertions are responsible for ~10% of spontaneous mutant phenotypes. We previously reported the phenotypes and genetic mapping of Polypodia, (Ppd), a spontaneous, X-linked dominant mutation with profound effects on body plan morphogenesis. Our new data shows that mutant mice are not born in expected Mendelian ratios secondary to loss after E9.5. In addition, we refined the Ppd genetic interval and discovered a novel ETnII-β early transposon insertion between the genes for Dusp9 and Pnck. The ETn inserted 1.6 kb downstream and antisense to Dusp9 and does not disrupt polyadenylation or splicing of either gene. Knock-in mice engineered to carry the ETn display Ppd characteristic ectopic caudal limb phenotypes, showing that the ETn insertion is the Ppd molecular lesion. Early transposons are actively expressed in the early blastocyst. To explore the consequences of the ETn on the genomic landscape at an early stage of development, we compared interval gene expression between wild-type and mutant ES cells. Mutant ES cell expression analysis revealed marked upregulation of Dusp9 mRNA and protein expression. Evaluation of the 5′ LTR CpG methylation state in adult mice revealed no correlation with the occurrence or severity of Ppd phenotypes at birth. Thus, the broad range of phenotypes observed in this mutant is secondary to a novel intergenic ETn insertion whose effects include dysregulation of nearby interval gene expression at early stages of development.
Public Health Emergency Preparedness and Response Communications with Health Care Providers: A Literature Review
Debra Revere, Kailey Nelson, Hanne Thiede, Jeffrey Duchin, Andy Stergachis, Janet Baseman
BMC Public Health , 2011, DOI: 10.1186/1471-2458-11-337
Abstract: A systematic review of peer- and non-peer-reviewed literature focused on the following questions: 1) What public health systems exist for communicating PHEPR messages from public health agencies to HCPs? 2) Have these systems been evaluated and, if yes, what criteria were used to evaluate these systems? 3) What have these evaluations discovered about characterizations of the most effective ways for public health agencies to communicate PHEPR messages to HCPs?We identified 25 systems or tools for communicating PHEPR messages from public health agencies to HCPs. Few articles assessed PHEPR communication systems or messaging methods or outcomes. Only one study compared the effectiveness of the delivery format, device or message itself. We also discovered that the potential is high for HCPs to experience "message overload" given redundancy of PHEPR messaging in multiple formats and/or through different delivery systems.We found that detailed descriptions of PHEPR messaging from public health to HCPs are scarce in the literature and, even when available are rarely evaluated in any systematic fashion. To meet present-day and future information needs for emergency preparedness, more attention needs to be given to evaluating the effectiveness of these systems in a scientifically rigorous manner.Public health emergency preparedness and response (PHEPR) involves activities directed at preventing possible emergencies and planning to ensure an adequate response and recovery if an emergency occurs. The public health system itself is a complex network of organizations and individuals that work together for the benefit of the public's health. These entities include public health agencies at local, state and federal levels, public safety agencies, emergency managers, academia, business, communities, the media, and the healthcare delivery system [1]. As one component of the PHEPR system, information contributed by health care providers (HCPs) to public health is aggregated, analyzed
HIV/AIDS and Associated Conditions among HIV-Infected Refugees in Minnesota, 2000–2007
Sara A. Lowther,Glenise Johnson,Brett Hendel-Paterson,Kailey Nelson,Blain Mamo,Kristina Krohn,Luisa Pessoa-Brand?o,Ann O'Fallon,William Stauffer
International Journal of Environmental Research and Public Health , 2012, DOI: 10.3390/ijerph9114197
Abstract: In 2010, the requirement for human immunodeficiency virus (HIV) testing of adult refugees prior to US resettlement was removed, thus leading to a potential for missed diagnosis. We reviewed refugee health assessment data and medical charts to evaluate the health status of HIV-infected refugees who arrived in Minnesota during 2000–2007, prior to this 2010 policy change. Among 19,292 resettled adults, 174 were HIV-infected; 169 (97%) were African (median age 26.4 (range: 17–76) years). Charts were abstracted for 157 (124 (79%) with ≥1 year of follow-up). At initial presentation, two of 74 (3%) women were pregnant; 27% became pregnant during follow-up. HIV clinical stage varied (59%, asymptomatic; 11%, mild symptoms; 10%, advanced symptoms; 3%, severe symptoms; 17%, unknown); coinfections were common (51 tuberculosis, 13?hepatitis B, 13 parasites, four syphilis). Prior to arrival 4% had received antiretrovirals. Opportunistic infections were diagnosed among 13%; 2% died from AIDS-related causes. Arrival screening may be needed to identify these HIV-infected refugees and prevent HIV-related morbidity and mortality.
Implementation of a Higher Quality dc Power Converter  [PDF]
N. N. Barsoum
Journal of Electromagnetic Analysis and Applications (JEMAA) , 2010, DOI: 10.4236/jemaa.2010.22012
Abstract: Many single and three-phase converters are well developed, and covered up in most of electric markets. It is used in many applications in power systems and machine drives. However, an exact definite output signal from the dc side still not recognized. The waveforms of output voltage and current demonstrate an imperfect dc signal and constitute losses, harmonic distortion, low power factor, and observed some ripples. An approximately perfect rectifier bridge is the aim of this research. Perhaps it gives the ability to identify the parameters of the converter to obtain, as much as possible, a perfect dc signal with less ripple, high power factor and high efficiency. Design is implemented by simulation on Power Simulator PSIM, and practically, a series regulator LM723 is applied to provide regulating output voltage. Comparisons of both simulation and hardware results are made to observe differences and similarities.
Estimation of Sensitivity of the DS/AHP Method While Solving Foresight Problems with Incomplete Data  [PDF]
N. Pankratova, N. Nedashkovskaya
Intelligent Control and Automation (ICA) , 2013, DOI: 10.4236/ica.2013.41011
Abstract:

The paper provides mathematical analysis of sensitivity of different combination rules in the DS/AHP method when an alternative is added to the set of decision alternatives while solving foresight problems. Different cases of rank reversals are defined and two sets of conditions for these cases using the method DS/AHP are considered. Rank reversals are illustrated when the DS/AHP method is used to solve practical problem of critical technologies of energy conservation and power efficiency evaluation in Ukraine. It is shown that the DS/AHP method is not sensitive to exclusion (or addition) of an irrelevant decision alternative from (or to) the set of decision alternatives.

Computation of the Genetic Code: Full Version  [PDF]
N. N. Kozlov
Journal of Computer and Communications (JCC) , 2017, DOI: 10.4236/jcc.2017.510008
Abstract: One of the problems in the development of mathematical theory of the genetic code (summary is presented in [1], the detailed—to [2]) is the problem of the calculation of the genetic code. Similar problem in the world is unknown and could be delivered only in the 21st century. One approach to solving this problem is devoted to this work. For the first time a detailed description of the method of calculation of the genetic code was provided, the idea of which was first published earlier [3]), and the choice of one of the most important sets for the calculation was based on an article [4]. Such a set of amino acid corresponds to a complete set of representation of the plurality of overlapping triple gene belonging to the same DNA strand. A separate issue was the initial point, triggering an iterative search process all codes submitted by the initial data. Mathematical analysis has shown that the said set contains some ambiguities, which have been founded because of our proposed compressed representation of the set. As a result, the developed method of calculation was reduced to two main stages of research, where at the first stage only single-valued domains were used in the calculations. The proposed approach made it possible to significantly reduce the amount of computation at each step in this complex discrete structure.
The Study of the Secrets of the Genetic Code  [PDF]
N. N Kozlov
Journal of Computer and Communications (JCC) , 2018, DOI: 10.4236/jcc.2018.67007
Abstract: The disclosure of many secrets of the genetic code was facilitated by the fact that it was carried out on the basis of mathematical analysis of experimental data: the diversity of genes, their structures and genetic codes. New properties of the genetic code are presented and its most important integral characteristics are established. Two groups of such characteristics were distinguished. The first group refers to the integral characteristics for the areas of DNA, where genes are broken down in pairs and all 5 cases of overlap, allowed by the structure of DNA, were investigated. The second group of characteristics refers to the most extended areas of DNA in which there is no genetic overlap. The interrelation of the established integral characteristics in these groups is shown. As a result, a number of previously unknown effects were discovered. It was possible to establish two functions in which all the over-understood codons in mitochondrial genetic codes (human and other organizations) participate, as well as a significant difference in the integral characteristics of such codes compared to the standard code. Other properties of the structure of the genetic code following from the obtained results are also established. The obtained results allowed us to set and solve one of the new breakthrough problems—the calculation of the genetic code. The full version of the solution to this problem was published in this journal in August 2017.
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