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Search Results: 1 - 10 of 401390 matches for " Kadivar M "
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Survey of cases with sepsis & septic shock in the pediatric intensive care unit of Children's Hospital Medical Centre
Salmanzadeh S,Kadivar M
Tehran University Medical Journal , 1999,
Abstract: Sepsis is the systemic response to severe infection in critically ill patients. Sepsis, septic syndrome & septic shock represent the increasingly severe stages of the same disease. Despite the remarkable improvements in outcome, sepsis & septic shock remain an important cause of morbidity & mortality in children. This is a retrospective study among the patients who were admitted in the pediatric intensive care unit (PICU) of Children's Hospital Medical Center from Farvardin 1371 till Esfand 1375. During this period 4018 children were admitted in the PICU, 138 of these patients (3.4%) had the initial diagnosis of sepsis or septic shock. The age of these patients were from 3 months to 14 years (mean of 23.5 months). The male to female ratio was 2.1:1. Out of these 138 patients only 16 cases (11.6%) had sepsis and the others (88.4%) had criterias of severe sepsis or septic shock. Multiple Organ Dysfunction (MOD) were found in 96 cases (69.3%). Diarrhea was the most common primary disease that resulted in sepsis or septic shock. Only 20.3% of the cultures were positive, among which E-Coli was the most in 8.7%, Staphylococcus aureus in 5.7%, Klebsiella in 2.9% and pseudomonas in 1.4%. 66.7% of these patients expired, the mortality rates of the patients with severe sepsis or septic shock that concommitantely had MOD were higher than the other (P<0.0005). So it may be better if children with clinical diagnosis of sepsis be hospitalized in an intensive care unit or at minimum in a facility that can closely monitor these patients during the initial stabilization period.
Evaluation of α-Amylase, Lipase and Lipoxygenase Activity in Wheat Flour before and after Germination
E Moharami,M SHahedi,M Kadivar
Journal of Science and Technology of Agriculture and Natural Resources , 2009,
Abstract: Enzymes of wheat flour have an important role in production of various cereal products, especially bread, and therefore accurate measurement of enzymatic activity along with improvement of this characteristic is the basis of most studies in baking industry. In the present work, physical properties of three wheat varieties (Mahdavi, Kavir and M7318 that are cultivated in Isfahan province) and chemical characteristics of their flours were investigated. In order to study the changes in enzymatic activities (α-amylase, lipase and lipoxygenase), the activities of these enzymes were measured before and after germination. The relationship between root length and α-amylase activity was studied as well as the relation between lipase and lipoxygenase activities. α-amylase activity of flours was also optimized according to falling number 250 s. The effect of this optimization on the bread texture in four different times after baking, on the flour color in three different times, and on the flour acidity in two different times were then evaluated. The results of chemical measurements showed that M7318 and other two varieties can be considered as weak flours and medium flours, respectively, in terms of their protein and gluten contents. However, all varieties had low levels of α-amylase activity, although, kavir flour had more activity than the others. The results of germination tests indicated an increase in the activity of α-amylase and lipase, but not lipoxygenase. Moreover, during germination times a significant negative correlation between root length and falling number was found. Also, a significant positive correlation between root length and α-amylase activity and between activities of lipase and lipoxygenase was observed.
A Neonate with Septic Shock and Multiorgan Dysfunction Because of Group A streptococci and Review of the Literatures
M Kadivar,S Haghi,F Mahjoub
Iranian Journal of Pediatrics , 2006,
Abstract: Objective: Group A streptococcus (streptococcus pyogenes) is a common cause of upper respiratory tract and skin infections, which may rarely infect other areas as well. Infection with this organism is rare in neonatal period. In addition to local infection such as omphalitis and celluitis, involvement of other sites like pneumonia, meningitis, osteomyelitis, and sepsis has been infrequently reported. Case Report: This report is about a 13-day-old male neonate who was admitted to the neonatal intensive care unit of the Children’s Medical Center in Tehran with respiratory distress, fever, and poor feeding, followed by patchy echymotic lesions over right lower limb which was gradually extended over entire body. 4 hours after hospitalization without any response to extensive management, he expired in septic shock state accompanied by multiorgan dysfunction, and disseminated intravascular coagulation (DIC). Blood culture was positive for Group A Streptococci. Autopsy revealed purulent involvement of various organs, and disseminated intravascular coagulation. Conclusion: Although infection with Group A Streptococci is rare in neonatal period, we should think about it, especially in a neonate with septic shock and multiorgan dysfunction with deep soft tissue involvement.
Determination of prevalence and causes of hyponatremia in patient's admitted in pediatric intensive care unit of the Children's Hospital Medical Center
Kadivar M,Dormanesh B,Madani A
Tehran University Medical Journal , 1999,
Abstract: Among the 708 patients who were admitted in the pediatric intensive care unit (PICU) of the children's hospital medical center, there were 100 patients with hyponatermia (Na<130 mEq/L). 62% of these patients had hyponatermia at the beginning of admission and 38% during hospitalization in PICU. According to the classification of hyponatermia in comparison to body fluid, this study revealed 7% pseudohyponatermia, 40% euvolemic hyponatermia, 34% hypovolemic hyponatermia and 10% hypovolemic hyponatermia. In conclusion, the most perevalent causes of hyponatermia in this study were syndrome of inappropriate antidiuretic hormone secretion (SIADH) (27%), water intoxication (22%) and extrarenal losses (20%)
THIAMINE–RESPONSIVE MEGALOBLASTIC ANEMIA, SENSORINEURAL DEAFNESS AND DIABETES MELLITUS
T. Zaman,M. Kadivar R. Moradian
Acta Medica Iranica , 2006,
Abstract: - The syndrome of diabetes mellitus, sensorineural deafness and megaloblastic anemia dose not result from thiamine deficiency. The previous reported patients had no sign of beriberi, had normal nutrition, and had no evidence of malabsorption. The features of this syndrome with apparent inheritance of autosomal recessive trait may define this puzzling syndrome as a true thiamine dependency state. The first Iranian patient was described by Vossough et al. in 1995. We found nine new cases with diagnostic criteria of thiamine responsive megaloblastic anemia during eight years of our study. In two patients, presentation of diabetes and anemia was concomitant. All of them were deaf with sensorineural hearing loss which was detected in infancy up to two years of age. The presence of congenital valvular heart disease was eliminated by normal echocardiography, but cardiomyopathy was discovered in two. Nonspecific amino-aciduria was discovered in three but urinary screening tests for hereditary orotic aciduria were negative. Ox-Phos biochemistry of muscle mitochondria which demonstrates severe defect in complexes I, III, IV in diabetes mellitus associated with deafness, were done but was unremarkable in our patients. Urinary methylmalonic acid and methyl malonyl carnitine by GS/MS and TMS was done in our patients and showed abnormal results in six patients. Thiamine gene, SLC 19A2, was detected in four patients.
Optimization of Food - Grade Gelatin Extraction from Cow Bonesby Acidic Method Using SREG
S. H. Hosseiniparvar,J. Keramat,M. Kadivar
Journal of Science and Technology of Agriculture and Natural Resources , 2007,
Abstract: This research was carried out to determine the optimum conditions for acidic extraction of gelatine from cattle bones. The effects of different treatments such as pH (1.8 to 2.6), temperature (60 to 80°C) and time (40 to 120minutes) on yield of extraction, gel strength, viscosity and absorption (420 nm) was measured. Coefficients of central composite rotatable design (CCRD) and regression surface response.... (RSREG) were used. The coefficients for yield, gel strength, viscosity and absorption were 0.990, 0.991, 0.998, 0.928, respectively. According to variance analysis of the data, there were significant differences between the effects of three variables (pH, temperature and time) on yield of extraction and viscosity, but no significant difference was observed between the effects of temperature and pH on gel strength and absorption, respectively. Comparisons of the averages of functional characteristics of acidic and commercial gelatin showed that viscosity and strength of acidic gelatin were higher than those of commercial one. The optimum conditions were found to be: pH=1.88, temp. 80°C and 118 min., to reach the highest yield and pH=1.88, temp. 60°C and 48 min. to get maximum strength, and pH=2.56, temp. 69°C and 118 min. to obtain the maximum viscosity and finally, pH=2.6, temp. 62°C and 48 min. for minimum absorption. Also, the results revealed that there were significant differences between trace elements content (Fe, Ca and Pb) of commercial and acidic gelatins. Although, acidic gelatin contained higher amount of the elements, but these amounts were still less than maximum values which are allowed to exist in gelatin. Amino acid compositions of both gelatins were almost identical.
The Effect of Blood Exchange Transfusion on Thyroid Function Tests
F Mostafavi,N Rostami,M Kadivar,M Tabrizi
Iranian Journal of Pediatrics , 1997,
Abstract: Blood exchange transfusion is a frequent procedure in neonatology units. At the same time Thyroid function tests are employed in neonatal screening. The changes of thyroid hormone level after blood exchange transfusion were not yet exactly determined. This prospective pilot study in 20 icteric newborns shows significant decrease in hormone concentration after blood exchange transfusion which rises to normal after three days for T4 and T3RU, whereas TSH level remains still low at this time.
MUMPS MYOCARDITIS AS A CAUSE OF NEONATAL CARDIOGENIC SHOCK
M. Kadivar,M. Sadighi,A. Kiani,A. Kocharian
Acta Medica Iranica , 2008,
Abstract: The mothers may be infected during pregnancy with infectious agents. Mumps induced myocarditis, especially endocardial fibroelastosis, was previously a common disease of infants but is rare now. A 25 day old male infant admitted to the intensive care of our hospital because of cardiogenic shock. Further studies revealed ischemic electrocardiograms, poor ventricular function, and positive results by polymerase chain reaction (PCR) technique for mumps virus. Regarding this case, although is very rare but mumps myocarditis should be included in the differential diagnosis of left ventricular dysfunction in neonatal period.
Antigenic variations of human influenza virus in Shiraz, Iran
Moattari A,Ashrafi H,Kadivar M,Kheiri M
Indian Journal of Medical Microbiology , 2010,
Abstract: Purpose: Influenza virus is a major cause of human respiratory infections and responsible for pandemics and regional outbreaks around the world. This investigation aims to determine the prevalent influenza genotypes during 2005-2007 outbreaks in Shiraz, the capital city of Fars province, southern Iran and compare the results obtained with those of previous study. Materials and Method: Of the 300 pharyngeal swabs collected from influenza patients, 26 were found to be positive by culture and hemagglutination (HA) assays. Typing and subtyping of the isolates carried out by using multiplex RT-PCR and phylogenetic analysis performed on isolated HA genes using neighbour-joining method. Result: Out of 26 positive isolates 12 and 14 were H1N1 and H3N2 respectively. The phylogenetic and amino acid sequence analyses of our H1N1 isolates showed 99-100% genetic resemblance to A/NewCaledonia/20/99 (H1N1) vaccine strain. Most of the Iranian H3N2 isolates varied form A/California/7/2004 vaccine strain in 20 amino acids of which positions 189,226 and 227 were located in antigenic sites of HA1 molecule. These substitutions were not observed in any of the H3N2 subtypes from the same region reported previously. Conclusion: The H3N2 subtype strains prevalent during the 2005/7 influenza outbreak in southern Iran demonstrated a drastic antigenic variation and differed from A/California/7/2004 vaccine strain. The H1N1 subtypes showed a notable resemblance to A/NewCaledonia/20/99 vaccine strain and therefore were predicted to be capable of conferring sufficient immunity against H1N1 subtypes.
Effect of Malting Process on Physicochemical Properties of Two Varieties of Barley (Sahra and Dasht)
M Kadivar,N Aghajani,H Hosini,M Kashni nejad
Journal of Science and Technology of Agriculture and Natural Resources , 2009,
Abstract: Since malting process of barley is greatly affected by the seed endosperm structure, getting information about its anatomical characteristics along with physico-chemical properties would be very important. The aim of this study was to measure length, width, thickness, kernel density, bulk density, porosity, total nitrogen, reducing sugar, diastatic activity, pH and color changes during malting process. Results showed that width, thickness, reducing sugar and diastatic activity of the samples increased over the malting time, whereas kernel density, bulk density and total nitrogen decreased (P
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