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Search Results: 1 - 10 of 138772 matches for " K. Sairam "
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Quality Control Studies of Mesua ferrea Linn. Flowers
Sahu Alakh N,Hemalatha S,Sairam K
International Journal of Herbal Medicine , 2013,
Abstract: Mesua ferrea Linn. belonging to the family Clusiaceae (alternatively Guttiferea). The flowers were fragrant, cream coloured, ebracteate, pedicellate, pedicel short, axillary, solitary or in pairs (cluster) and 2.5-7.5 cm in diameter, bisexual and buds were sub-globose. The transverse section showed numerous multicellular and multiseriate type trichomes on the upper layer of the epidermis. Foreign organic matter (0.47% w/w), total ash (6.30% w/w), acid insoluble ash (2.30 % w/w), water soluble ash (2.31 % w/w), alcohol soluble extractive (20.53 % w/w), water soluble extractive (10.26 % w/w), loss on drying (9.88 %), foaming index (333.3), swelling index (0.53 ml) and volatile oil (0.20 % v/w) of the crude drug were been obtained. A fingerprint of fluorescence was obtained. Chlorinated pesticide in first and second elute from column were 0.030 and 0.013 respectively and phosphated pesticides in first elute was 0.028 mg/kg of crude drug. Preliminary phytochemical screening showed the presence of many phytochemicals.
Case Study: CFD Application for Building Evaluation
Ramisetti Sairam,K Jaideep,P L Raviteja
International Journal on Theoretical and Applied Research in Mechanical Engineering , 2013,
Abstract: From Uphaar Fire Tragedy to recent Mumbai Secretariat Fire accident shows how Vulnerable are Old Constructions, while new one are well designed with Necessary Fire Protection Systems. It is well known fact many of Old Structures in India doesn’t have basic Fire Protection systems such as F.E. This paper is intended to study one of such old Constructions, a college Auditorium and Evaluate risk on loss of Life due to Suffocation and Thermal Injuries using Simulation
Effect of Protonation on the electronic properties of DNA base pairs: Applications for molecular electronics
Sairam S. Mallajosyula,Swapan K Pati
Physics , 2007,
Abstract: Protonation of DNA basepairs is a reversible phenomenon which can be controlled by tuning the pH of the system. Under mild acidic conditions, the hydrogen bonding pattern of the DNA basepairs undergoes a change. We study the effect of protonation on the electronic properties of the DNA basepairs to probe for possible molecular electronics applications. We find that, under mild acidic pH conditions, the A:T basepair shows excellent rectification behaviour which is, however, absent in the G:C basepair. The mechanism of rectification has been discussed using a simple chemical potential model. We also consider the non-canonical A:A basepair and find that it can be used as efficient pH dependent molecular switch. The switching action in A:A basepair is explained in the light of pi-pi interactions which lead to efficient delocalization over the entire basepair.
Peak-To-Average Power Reduction In Mimo-Ofdm Systems Using Sub-Optimal Algorithm
K Srinivasarao,B Prabhakararao,M V S Sairam
International Journal of Distributed and Parallel Systems , 2012,
Abstract: Multiple-input multiple-output orthogonal frequency division multiplexing (MIMO-OFDM) technology is one of the most attractive candidates for fourth generation (4G) mobile radio communication. It effectively combats the multipath fading channel and improves the bandwidth efficiency. At the same time, it also increases system capacity so as to provide a reliable transmission. However, the main drawback of MIMO-OFDM system is high peak-to-average power ratio (PAPR) for large number of sub-carriers, which result in many restrictions for practical applications. Coding, phase rotation and clipping are among many PAPR reduction schemes that have been proposed to overcome this problem. In this paper, we mainly investigate the PAPR reduction performance with two different PAPR reduction methods: partial transmit sequence (PTS) and selective mapping (SLM). These two methods are sub-entities of phase rotation scheme. We propose an algorithm, Sub-Optimal algorithm that shows better PAPR reduction compared to the existing algorithms. Results are verified using MATLAB software.
Competent Smart Car Parking: An OSGi Approach
Kaushik Gopalan,K. Sairam,R. Nandakrishnan,Veeramuthu Venkatesh
Journal of Artificial Intelligence , 2013,
Abstract: In cosmopolitan expanses, parking of vehicles has become a major problem as it is becoming unproductive. It is also one of the key causes of city traffic congestion. A mechanism is needed to monitor the parking area. Other associated issues such as lighting of large parking lots and tracking availability of parking spots need to be addressed. The proposed study discussed these issues and gave a solution by employing Open Source Gate Initiative (OSGi), a middleware that helps in efficient communication. The parking system discussed here integrates various communication standards such as the SMS features of a standardized mobile, ZigBee enabled proximity sensors and a system meant for storage and processing of the data. The proposed architecture eliminates the hassles of searching empty parking spots and thus can save a lot of time on a daily basis for the general public who own and use a vehicle for commuting. The merits of this study compared with the existing models are emphasized here. This study also highlighted the advantages of using a standardized middleware such as OSGi for the communication between sensors and a system meant for the storage and processing of the obtained data.
Organometallic Vanadium-Borazine Systems: Efficient One- Dimensional Half-Metallic Spin Filters
Sairam S. Mallajosyula,Prakash Parida,Swapan K. Pati
Physics , 2009,
Abstract: Using density functional theory, we have investigated the electronic and magnetic properties of finite-size as well as infinitely periodic organometallic vanadium-borazine systems for their possible applications in spintronics devices. From our calculations, we find the finite-size vanadium-borazine systems to be structurally more stable in comparison to their isoelectronic benzene counterparts. All the finite-size vanadium-borazine systems are found to be ferromagnetically stabilized, with the infinite one-dimensional wire exhibiting robust half-metallic behaviour. The finite-size clusters are also found to exhibit efficient spin filter properties when coupled to graphene electrodes.
The Influence of Radial Area Variation on Wind Turbines to the Axial Induction Factor  [PDF]
Kedharnath Sairam, Mark G. Turner
Energy and Power Engineering (EPE) , 2014, DOI: 10.4236/epe.2014.611034
Abstract: Improvements in the aerodynamic design will lead to more efficiency of wind turbines and higher power production. In the present study, a 3D parametric gas turbine blade geometry building code, 3DBGB, has been modified in order to include wind turbine design capabilities. This approach enables greater flexibility of the design along with the ability to design more complex geometries with relative ease. The NREL NASA Phase VI wind turbine was considered as a test case for validation and as a baseline by which modified designs could be compared. The design parameters were translated into 3DBGB input to create a 3D model of the wind turbine which can also be imported into any CAD program. Design modifications included replacing the airfoil section and modifying the thickness to chord ratio as a function of span. These models were imported into a high-fidelity CFD package, Fine/TURBO by NUMECA. Fine/TURBO is a specialized CFD platform for turbo-machinery analysis. A code-geomturbo was used to convert the 3D model of the wind turbine into the native format used to define geometries in the Fine/TURBO meshing tool, AutoGrid. The CFD results were post processed using a 3D force analysis code. The radial force variations were found to play a measurable role in the performance of wind turbine blades. The radial component of the blade surface area as it varies in span is the dominant contributor of the radial forces. Through the radial momentum equation, this radial force variation is responsible for creating the streamline curvature that leads to the expansion of the streamtube (slipstream) that is responsible for slowing the wind velocity ahead of the wind turbine leading edge, which is quantified as the axial induction factor. These same radial forces also play a role in changing the slipstream for propellers. Through the design modifications, simulated with CFD and post-processed appropriately, this connection with the radial component of area to the radial forces to the axial induction factor, and finally the wind turbine power is demonstrated. The results from the CFD analysis and 3D force analysis are presented. For the case presented, the power increases by 5.6% due to changes in airfoil thickness only.
Case Study : Evaluation Smoke & Evacuation Performance of a College Auditorium
Ramisetti Sairam
International Journal on Theoretical and Applied Research in Mechanical Engineering , 2012,
Abstract: From Uphaar Fire Tragedy to recent Mumbai Secretariat Fire accident shows how Vulnerable are Old Constructions, while new one are well designed with Necessary Fire Protection Systems. It is well known fact many of Old Structures in India doesn’t have basic Fire Protection systems such as F.E. This paper is intended to study one of such old Constructions, a college Auditorium and evaluate risk on loss of Life due to Suffocation and Thermal Injuries using Simulation. The understanding of smoke and Behavior aspects of Man at the time of Fire helps to Design efficient Smoke Management systems.
Three Dimensional Pharmacophore Modelling of Monoamine oxidase-A (MAO-A) inhibitors
Kalapatapu V.V.M. Sairam,Roop K. Khar,Rama Mukherjee,Swatantra K. Jain
International Journal of Molecular Sciences , 2007, DOI: 10.3390/i8090894
Abstract: Flavoprotein monoamine oxidase is located on the outer membrane ofmitochondria. It catalyzes oxidative deamination of monoamine neurotransmitters such asserotonin, norepinephrine and dopamine and hence is a target enzyme for antidepressantdrugs. MAO (mono amine oxidase) has two isoforms, namely MAO-A and MAO-B.MAO-A isoform has higher affinity for serotonin and norepinephrine, while; MAO-Bpreferentially deaminates phenylethylamine and benzylamine. These important propertiesdetermine the clinical importance of MAO inhibitors. Selective MAO-A inhibitors are usedin the treatment of neurological disorders such as depression. In this article we havedeveloped a Hypogen pharmacophore for a set of 64 coumarin analogs and tried to analyzethe intermolecular H-bonds with receptor structure.
Dual-Modality, Dual-Functional Nanoprobes for Cellular and Molecular Imaging
Jyothi U. Menon, Praveen K. Gulaka, Madalyn A. McKay, Sairam Geethanath, Li Liu, Vikram D. Kodibagkar
Theranostics , 2012,
Abstract: An emerging need for evaluation of promising cellular therapies is a non-invasive method to image the movement and health of cells following transplantation. However, the use of a single modality to serve this purpose may not be advantageous as it may convey inaccurate or insufficient information. Multi-modal imaging strategies are becoming more popular for in vivo cellular and molecular imaging because of their improved sensitivity, higher resolution and structural/functional visualization. This study aims at formulating Nile Red doped hexamethyldisiloxane (HMDSO) nanoemulsions as dual modality (Magnetic Resonance Imaging/Fluorescence), dual-functional (oximetry/detection) nanoprobes for cellular and molecular imaging. HMDSO nanoprobes were prepared using a HS15-lecithin combination as surfactant and showed an average radius of 71±39 nm by dynamic light scattering and in vitro particle stability in human plasma over 24 hrs. They were found to readily localize in the cytosol of MCF7-GFP cells within 18 minutes of incubation. As proof of principle, these nanoprobes were successfully used for fluorescence imaging and for measuring pO2 changes in cells by magnetic resonance imaging, in vitro, thus showing potential for in vivo applications.
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