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Search Results: 1 - 10 of 138722 matches for " K. Randle "
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The Importance of Extensor Mechanism in the Success of Patello-Femoral Arthroplasty  [PDF]
Rajkumar Krishnan, Ray Randle
Open Journal of Orthopedics (OJO) , 2014, DOI: 10.4236/ojo.2014.48036
Abstract: Anterior knee pain is a common symptom in general orthopedic practice and is reported in 8% of women and 2% of men over the age of 55 years. The treatment of isolated patellofemoral arthritis is controversial. Many patients can be effectively managed conservatively. Analysis was done on 14 patients (17 knees) with symptomatic isolated patellofemoral osteoarthritis between 2001 and 2007. 3 patients had additional procedures like tibial tubercle osteotomy and lateral release, tibial tubercle osteotomy with medical plication and iliotibial band lengthening and lateral retinacular release. The operation should be viewed as a soft-tissue procedure involving resurfacing of the femoral trochlea and the articular surface of the patella. Proper balance of the extensor mechanism must be done at the time of surgery to ensure correct tracking of the patella which in turn results in the best outcome for the replacement.
Ubiquitous healthcare monitoring system using integrated triaxial accelerometer,spo2 and location sensors
O. O. Ogunduyile,K. Zuva,O. A. Randle,T. Zuva
Computer Science , 2013, DOI: 10.5121/iju.2013.4201
Abstract: Ubiquitous healthcare has become one of the prominent areas of research inorder to address the challenges encountered in healthcare environment. In contribution to this area, this study developed a system prototype that recommends diagonostic services based on physiological data collected in real time from a distant patient. The prototype uses WBAN body sensors to be worn by the individual and an android smart phone as a personal server. Physiological data is collected and uploaded to a Medical Health Server (MHS) via GPRS/internet to be analysed. Our implemented prototype monitors the activity, location and physiological data such as SpO2 and Heart Rate (HR) of the elderly and patients in rehabilitation. The uploaded information can be accessed in real time by medical practitioners through a web application.
Study of systematic errors on the scalar boson mass
Aidan Randle-Conde
Physics , 2015,
Abstract: In this talk I presented studies of the scalar boson mass resolution at the LHC. I described in detail the limiting factors on resolution, the methods used to determine the mass resolution, and the statistical sample size required for these results for the ZZ* and diphoton final states. I finished the talk by comparing projections for various linear collider scenarios.
ACL reconstruction with unicondylar replacement in knee with functional instability and osteoarthritis
Srikrishna RSR Krishnan, Ray Randle
Journal of Orthopaedic Surgery and Research , 2009, DOI: 10.1186/1749-799x-4-43
Abstract: Isolated unicompartmental osteoarthritis of the knee is common. Operative treatment varies from high tibial osteotomy, unicompartmental knee replacement and total knee replacement according to the age of the patient and the level of activity [1]. Severe osteoarthritis of one compartment in young and active patients with pre-existing deficiency of the anterior cruciate ligament (ACL) and severe functionally instability is a difficult subgroup to manage [2].There is considerable debate regarding management of young patients with isolated unicompartment osteoarthritis and concomitant ACL deficiency. The aim of the treatment should be to offer a procedure that will give lasting relief of symptoms and will not compromise any future surgery. Various surgical options have been described, including arthroscopic debridement, reconstruction of the ACL, high tibial osteotomy with or without ACL reconstruction, unicompartmental knee arthroplasty and total knee replacement [2]. None of these address the two major symptoms apart from total knee replacement.The advantages of unicompartmental arthroplasty over total knee replacement are preservation of bone stock, less invasive surgery, minimal blood loss, faster recovery, better range of movement and more physiological function [3]. It is also more cost-effective than total knee replacement [4].Recent studies have shown that, with the proper patient selection and surgical technique, UKA can have performance and survivorship comparable with total knee arthroplasty or high tibial osteotomy [5].The anterior cruciate ligament (ACL) is the primary restraint to anterior tibial translation in the native knee [6]. It has been suggested that the ACL also plays an important role in the successful outcome of UKA [7-9]. Unicompartmental knee arthroplasty can provide disappointing long-term results when the ACL is deficient [10,11].Good fellow found a greater incidence of failure of mobile-bearing UKA when the ACL was deficient [7]. A nonfunct
Familiarising Probabilistic Distance Clustering System of Evolving Awale Player
Randle Oluwarotimi Abayomi,Keneilwe Zuva
International Journal on Applications of Graph Theory in Wireless ad hoc Networks and Sensor Networks , 2012,
Abstract: This study developed a new technique based on Probabilistic Distance Clustering (PDC) for evolvingAwale player and to compare its performance with that of a technique based on approximation of minimumand maximum operators with generalized mean-value operator. The basic theory of pd-clustering is basedon the assumption that the probability of an Euclidean point belonging to a cluster is inverselyproportional to its distance from the cluster centroid. Treating game strategies as a vector space model, itis possible to extend pd-clustering technique to game playing by estimating the probability that a givenstrategy is in a certain cluster of game strategies. As a result, the strategy that has the highest probabilityand shortest distance to a cluster of alternative strategies is recommended for the player.
Inter-Group Conflict in Health Care: UK Students’ Experiences of Bullying and the Need for Organisational Solutions
Keith Stevenson,Jacqueline Randle,Ian Grayling
Online Journal of Issues in Nursing , 2006,
Abstract: This paper addresses bullying of United Kingdom (UK) nursing students whilst on work placement as a specific issue of inter-group difficulty that currently affects nurses and students working in the UK National Health Service. The authors begin by discussing the concept of bullying and sharing the types of bullying reported in two recent studies involving UK nursing students. Both studies illustrate the effects that negative workplace experiences can have on new entrants to the profession. After reviewing various individual solutions which have been recommended for reducing bullying, they suggest that the most effective solution is for health care organisations offering placement training to become much more proactive in creating a culture that will not tolerate bullying behaviour by staff at any level. The literature suggests bullying is a phenomenon affecting workplaces in many countries. Thus the issues described in this article, and the solutions offered have relevance to a variety of health care settings.
The Myths of Restoration Ecology
Robert H. Hilderbrand,Adam C. Watts,April M. Randle
Ecology and Society , 2005,
Abstract:
Thymic Microenvironment and Lymphoid Responses toSublethal Irradiation
Elise S. Randle-Barrett,Richard L. Boyd
Clinical and Developmental Immunology , 1995, DOI: 10.1155/1995/14923
Abstract:
Modeling of octave-spanning Kerr frequency combs using a generalized mean-field Lugiato-Lefever model
Stephane Coen,Hamish G. Randle,Thibaut Sylvestre,Miro Erkintalo
Physics , 2012, DOI: 10.1364/OL.38.000037
Abstract: A generalized Lugiato-Lefever equation is numerically solved with a Newton-Raphson method to model Kerr frequency combs. We obtain excellent agreement with past experiments, even for an octave-spanning comb. Simulations are much faster than with any other technique despite including more modes than ever before. Our study reveals that Kerr combs are associated with temporal cavity solitons and dispersive waves, and opens up new avenues for the understanding of Kerr comb formation.
Expression of Fbxo7 in Haematopoietic Progenitor Cells Cooperates with p53 Loss to Promote Lymphomagenesis
Mikhail Lomonosov, El Kahina Meziane, Hongtao Ye, David E. Nelson, Suzanne J. Randle, Heike Laman
PLOS ONE , 2011, DOI: 10.1371/journal.pone.0021165
Abstract: Fbxo7 is an unusual F box protein that augments D-type cyclin complex formation with Cdk6, but not Cdk4 or Cdk2, and its over-expression has been demonstrated to transform immortalised fibroblasts in a Cdk6-dependent manner. Here we present new evidence in vitro and in vivo on the oncogenic potential of this regulatory protein in primary haematopoietic stem and progenitor cells (HSPCs). Increasing Fbxo7 expression in HSPCs suppressed their colony forming ability in vitro, specifically decreasing CD11b (Mac1) expression, and these effects were dependent on an intact p53 pathway. Furthermore, increased Fbxo7 levels enhanced the proliferative capacity of p53 null HSPCs when they were grown in reduced concentrations of stem cell factor. Finally, irradiated mice reconstituted with p53 null, but not wild-type, HSPCs expressing Fbxo7 showed a statistically significant increase in the incidence of T cell lymphoma in vivo. These data argue that Fbxo7 negatively regulates the proliferation and differentiation of HSPCs in a p53-dependent manner, and that in the absence of p53, Fbxo7 expression can promote T cell lymphomagenesis.
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