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Search Results: 1 - 10 of 400035 matches for " K. J. Sampath "
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Modified Cooperative Subchannel Allocation Algorithms and PSO Based Power Allocation for an Alamouti Decode and Forward Relaying Protocol in Multiuser OFDMA Systems  [PDF]
K. Shoukath Ali, P. Sampath
Circuits and Systems (CS) , 2016, DOI: 10.4236/cs.2016.78153
Abstract: The present work is a discussion on the performance analysis of Modified Cooperative Subchannel Allocation (CSA) Algorithms which is used in Alamouti Decoded and Forward (Alamouti DF) Relaying Protocol for wireless multi-user Orthogonal Frequency Division Multiplexing Access (OFDMA) systems. In addition, the performance of approximate Symbol Error Rate (SER) for the Alamouti DF Relaying Protocol with the Cooperative Maximum Ratio Combining Technique (C-MRC)is analyzed and compared with SER upper bound. The approximate SER is asymptotically tight bound at higher Signal-to-Noise Ratio (SNR). From the asymptotic tight bound approximate SER, Particle Swarm Optimization (PSO) based Power Allocation (PA) is determined for the Alamouti DF Relaying Protocol. The simulation results suggested that the Modified Throughput based Subchannel Allocation Algorithm achieved an improved throughput of 6% to 33% compared to that of existing cooperative diversity protocol. Further, the Modified Fairness based Subchannel Allocation Algorithm rendered fairness of 7.2% to 17% among the multiuser against the existing cooperative diversity protocol.
A Rare Case of Synchronous Presentation of Acute Myeloid Leukemia and Lung Cancer  [PDF]
K. J. Sampath, J. Pridvi, A. Anil, K. Ranjith, L. Swati, S. Nishant
Journal of Cancer Therapy (JCT) , 2019, DOI: 10.4236/jct.2019.106039
Abstract: Background: There are very few publications on synchronous presentation of dual malignancies in the literature. Occurrence of second malignancy in a patient with a known malignant tumor is not uncommon, though synchronous primary malignancies are unusual. Case Presentation: A 77-year-old man was diagnosed elsewhere as squamous cell carcinoma of lung came to our oncology department for further management. He underwent bone marrow evaluation with the suspicious of metastasis in view of pancytopenia. On bone marrow evaluation, found to have prominence of blasts more than 20%, which were CD34 positive and CD117 positive and. Conclusion: Here we describe an unusual rare combination of synchronous presentation of acute myeloid leukemia and squamous cell carcinoma of lung.
Cardiomyopathy-Related Mutations in Cardiac Troponin C, L29Q and G159D, Have Divergent Effects on Rat Cardiac Myofiber Contractile Dynamics
Sampath K. Gollapudi,Murali Chandra
Biochemistry Research International , 2012, DOI: 10.1155/2012/824068
Abstract: Previous studies of cardiomyopathy-related mutations in cardiac troponin C (cTnC)—L29Q and G159D—have shown diverse findings. The link between such mutant effects and their divergent impact on cardiac phenotypes has remained elusive due to lack of studies on contractile dynamics. We hypothesized that a cTnC mutant-induced change in the thin filament will affect global myofilament mechanodynamics because of the interactions of thin filament kinetics with both Ca2
Information and communication technology in disease surveillance, India: a case study
Kant Lalit,Krishnan Sampath K
BMC Public Health , 2010, DOI: 10.1186/1471-2458-10-s1-s11
Abstract: India has made appreciable progress and continues to demonstrate a strong commitment for establishing and operating a disease surveillance programme responsive to the requirements of the International Health Regulations (IHR[2005]). Within five years of its launch, India has effectively used modern information and communication technology for collection, storage, transmission and management of data related to disease surveillance and effective response. Terrestrial and/or satellite based linkages are being established within all states, districts, state-run medical colleges, infectious disease hospitals, and public health laboratories. This network enables speedy data transfer, video conferencing, training and e-learning for outbreaks and programme monitoring. A 24x7 call centre is in operation to receive disease alerts. To complement these efforts, a media scanning and verification cell functions to receive reports of early warning signals. During the 2009 H1N1 outbreak, the usefulness of the information and communication technology (ICT) network was well appreciated. India is using ICT as part of its Integrated Disease Surveillance Project (IDSP) to help overcome the challenges in further expansion in hard-to-reach populations, to increase the involvement of the private sector, and to increase the use of other modes of communication like e-mail and voicemail.
Cardiomyopathy-Related Mutations in Cardiac Troponin C, L29Q and G159D, Have Divergent Effects on Rat Cardiac Myofiber Contractile Dynamics
Sampath K. Gollapudi,Murali Chandra
Biochemistry Research International , 2012, DOI: 10.1155/2012/824068
Abstract: Previous studies of cardiomyopathy-related mutations in cardiac troponin C (cTnC)—L29Q and G159D—have shown diverse findings. The link between such mutant effects and their divergent impact on cardiac phenotypes has remained elusive due to lack of studies on contractile dynamics. We hypothesized that a cTnC mutant-induced change in the thin filament will affect global myofilament mechanodynamics because of the interactions of thin filament kinetics with both C a 2 + binding and crossbridge (XB) cycling kinetics. We measured pCa-tension relationship and contractile dynamics in detergent-skinned rat cardiac papillary muscle fibers reconstituted with the recombinant wild-type rat cTnC ( c T n C W T ), c T n C L 2 9 Q , and c T n C G 1 5 9 D mutants. c T n C L 2 9 Q fibers demonstrated a significant decrease in C a 2 + sensitivity, but c T n C G 1 5 9 D fibers did not. Both mutants had no effect on C a 2 + -activated maximal tension. The rate of XB recruitment dynamics increased in c T n C L 2 9 Q (26%) and c T n C G 1 5 9 D (25%) fibers. The rate of XB distortion dynamics increased in c T n C G 1 5 9 D fibers (15%). Thus, the c T n C L 2 9 Q mutant modulates the equilibrium between the non-cycling and cycling pool of XB by affecting the on/off kinetics of the regulatory units (Tropomyosin-Troponin); whereas, the c T n C G 1 5 9 D mutant increases XB cycling rate. Different effects on contractile dynamics may offer clue regarding how c T n C L 2 9 Q and c T n C G 1 5 9 D cause divergent effects on cardiac phenotypes. 1. Introduction The presumptive conclusion drawn from the heterogenic nature of human cardiomyopathy suggests a link between the type of mutation and the nature of pathological remodeling of the heart. A growing number of mutations in human cardiac troponin C (cTnC), associated with either hypertrophic cardiomyopathy (HCM) or dilated cardiomyopathy (DCM), makes it a prominent target gene for functional characterization. Thus far, 5 mutations in cTnC are found to be associated with HCM and 6 with DCM. These HCM-linked cTnC mutations include L29Q [1]—A8V, C84Y, and E134D [2]—Q122AfsX30 [3], while the DCM-linked cTnC mutations include E59D/D75Y [4], G159D [5]—Y5H, M103I, D145E, and I148V [6]. cTnC comprises two globular lobes; the amino-(N) and the carboxyl-(C) terminal lobes, which are connected by a flexible linker. The binding of C a 2 + to the regulatory site-II of the N-lobe of cTnC is important for triggering structural changes in the regulatory unit (RU), consisting of troponin (Tn) and tropomyosin (Tm). The binding of C a 2 + to cTnC has a
Solution of an integral equation with a logarithmic kernel
C. Sampath,D. J. Jain
International Journal of Mathematics and Mathematical Sciences , 1990, DOI: 10.1155/s0161171290001053
Abstract: A simple independent integral equation technique is presented to solve an integral equation with a logarithmic kernel which governs solutions of many two-dimensional Dirichlet boundary value problems involving two coplanar and parallel infinite strips. The technique is further illustrated by an example.
Exploiting System Hierarchy to Compute Repair Plans in Probabilistic Model-based Diagnosis
Sampath Srinivas,Eric J. Horvitz
Computer Science , 2013,
Abstract: The goal of model-based diagnosis is to isolate causes of anomalous system behavior and recommend inexpensive repair actions in response. In general, precomputing optimal repair policies is intractable. To date, investigators addressing this problem have explored approximations that either impose restrictions on the system model (such as a single fault assumption) or compute an immediate best action with limited lookahead. In this paper, we develop a formulation of repair in model-based diagnosis and a repair algorithm that computes optimal sequences of actions. This optimal approach is costly but can be applied to precompute an optimal repair strategy for compact systems. We show how we can exploit a hierarchical system specification to make this approach tractable for large systems. When introducing hierarchy, we also consider the tradeoff between simply replacing a component and decomposing it to repair its subcomponents. The hierarchical repair algorithm is suitable for off-line precomputation of an optimal repair strategy. A modification of the algorithm takes advantage of an iterative deepening scheme to trade off inference time and the quality of the computed strategy.
Vector Modulator for Phase Shifting in Passive Beamforming Wireless Systems
P.Sampath,,K.Gunavathi
International Journal of Engineering Science and Technology , 2010,
Abstract: This paper proposes vector modulator for changing the phase of a signal in passive beamforming system. Vector modulator is used to perform a phase shift function with added benefit of amplitude control. It is used to improve the directivity of RF waves in Wireless systems. Vector modulator is implemented for a center frequency of 902.5 MHz. The simulation is performed for individual blocks of the vector modulator and for vector modulator with JFET and MOSFET as controlling device in the variable attenuator of the vector modulator.
EXPERIMENTAL INVESTIGATION OF COLD START EMISSIONS USING ELECTRICALLY HEATED CATALYSTS IN A SPARK IGNITION ENGINE
K. Bhaskar,G. Nagarajan,S. Sampath
International Journal of Automotive and Mechanical Engineering , 2010,
Abstract: The population of spark-ignition vehicles in urban areas is very high and is increasing rapidly due to their convenience for short distance transportation. These vehicles are major sources of urban air pollution compared to vehicles with diesel engines. Catalytic converters are used to control their emissions but they attain their maximum conversion rates of about 80% –90% under optimum operating conditions and are not effective during cold start conditions. The objective of the present work is to demonstrate that an electrically heated catalyst (EHC) in combination with a traditional converter can achieve the Low and Ultra Low Emission Vehicle (LEV, ULEV) standards. Experiments were conducted to investigate the impact of various metal oxides in EHC and design parameters to reduce cold-start emissions of a multi-cylinder SI engine. It is observed that EHC reduces cold-start hydrocarbon and carbon monoxide emissions when used with an existing catalytic converter. The maximum CO and HC reductions were achieved with copper oxide as the catalyst in EHC with air injection of 80 lpm for 40 sec after cold start of the engine.
EMERGING PERSPECTIVES OF RISK AND MEDICATION IN PREGNANCY
K.P.Sampath Kumar*
International Journal of Pharmacy and Technology , 2010,
Abstract: Pregnancy is an exciting time in a woman's life. Changes in your body may be matched by changes in your emotions. During pregnancy, some medications are safe and some are not. Some require a higherthan usual dose, and some doses change with the advancing pregnancy. Physicians responsible for providing care to pregnant women are aware of these different medications and their restrictions. A mother taking illegal drugs during pregnancy increases her risk for anaemia, blood and heart infections,skin infections, hepatitis, and other infectious diseases. A woman's drug use can affect both her foetusand her newborn. Most drugs cross the placenta--the organ that provides nourishment to the foetus.Some can cause direct toxic (poisonous) effects and drug dependency in the foetus. After birth, some drugs can be passed to the baby through breast-feeding. More than 90% of pregnant women take prescription or nonprescription (over-the-counter) drugs or use social drugs (such as tobacco andalcohol) or illicit drugs at some time during pregnancy. Cocaine use can lead to premature delivery of the foetus, premature detachment of the placenta, high blood pressure, and stillbirth. The criticalperiod of embryonic development, when the major organ systems develop, starts at about 17 days post-conception and is complete by 60 to 70 days. In general, drugs, unless absolutely necessary,should not be used during pregnancy because many can harm the fetus. About 2 to 3% of all birth defects result from the use of drugs other than alcohol.
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