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Search Results: 1 - 10 of 405238 matches for " K. J. Ho "
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Reducing the Edge Chipping for Capillary End Face Grinding and Polishing
Ho?ek J.,Studenovsky K.
EPJ Web of Conferences , 2013, DOI: 10.1051/epjconf/20134800005
Abstract: This paper presents results of glass capillary end face grinding and polishing by approach that reduces the edge chipping. Brittle materials have natural tendency for edge chipping what leads to beveling the sharp edges. Not beveled sharp edges on glass capillary are important for special applications like surface tension measurement of small liquid samples. We use common grinding and polishing process for capillary end face machining modified with gradual decreasing of grinding load based on the relation of the critical chipping load. Achieved surface roughness is measured using atomic force microscopy (AFM). Capillary inner edge quality is checked both with optical microscopes and electron microscope too. We achieved a non-chipped capillary inner edge with radius down to 100 nm.
S. Young Ho,J. Hyun Lyung,K. Ho Youl
Biology of Sport , 2011,
Abstract: The incidence of bone fractures has increased in the current decade due to osteoporosis. Bone mineral density (BMD), or the amount of mineralized bone, is an important determinant of risk for bone fractures. Bone mineralization is strongly stimulated by weight-bearing exercise during growth and development. Taekwondo, a Korean martial art, is a well-known form of strenuous and weight-bearing physical activity. Therefore, the primary goal of this study was to determine the effects of taekwondo training on the bone health of female high school students in Korea. The secondary goal of this study was to clarify the relationships between body weight and BMD in this sample. Thirty taekwondo players (TKD) and 30 sedentary high school girls (CON) voluntarily participated in the present study and were split into three groups by weight: light weight (L) under 51 kg; middle weight (M) between 51 and under 57 kg; and heavy weight (H) over 57 kg. BMD was determined from dual-emission X-ray absorptiometry (DEXA), and percent body fat was measured by the skin-fold method. Lumbar spine and femoral BMD were not significantly different between light, middle and heavy body weight groups. However, the average BMD in the TKD group was significantly greater than in the CON group for all lumbar spine regions (P<0.05). The results of this study suggest that taekwondo training during growth significantly improved bone health in all weight groups.
Sensors for Environmental Monitoring
Clifford K. Ho,M. J. Sch?ning
Sensors , 2005, DOI: 10.3390/s5010001
Abstract: No abstract available
Molecular dynamic simulation of a homogeneous bcc -> hcp transition
J. R. Morris,K. M. Ho
Physics , 2001, DOI: 10.1103/PhysRevB.63.224116
Abstract: We have performed molecular dynamic simulations of a Martensitic bcc->hcp transformation in a homogeneous system. The system evolves into three Martensitic variants, sharing a common nearest neighbor vector along a bcc <111> direction, plus an fcc region. Nucleation occurs locally, followed by subsequent growth. We monitor the time-dependent scattering S(q,t) during the transformation, and find anomalous, Brillouin zone-dependent scattering similar to that observed experimentally in a number of systems above the transformation temperature. This scattering is shown to be related to the elastic strain associated with the transformation, and is not directly related to the phonon response.
Critical Limb Ischaemia in Adult Human Skeletal Muscle Increases Satellite Cell Proliferation but Not Differentiation  [PDF]
C. A. Hart, J. Tsui, K. Khan, T. K. Ho, X. Shiwen, M. Ponticos, D. Abraham, D. M. Baker
Surgical Science (SS) , 2015, DOI: 10.4236/ss.2015.65031

Critical Limb Ischaemia (CLI) is defined as the presence of rest pain, ulcers and/or gangrene in a limb for over 2 weeks. Associated exercise intolerance is caused by muscle fibre atrophy, fibro- fatty infiltration, nerve dysfunction, mitochondrial damage and myofibril disorder. We aimed to determine the behaviour of satellite cells, responsible for the repair and regeneration of damaged muscle, in repairing the damage caused to critically ischaemic adult human skeletal muscle. CD34, pax7 and MyoD are all markers of satellite cells at different stages of the cell cycle and allow for an assessment of their number and activity in ischaemia. Local ethical committee approval and informed consent was obtained. Samples of harvested gastrocnemius muscle of patients undergoing major perigenicular amputation for CLI (n = 10) were analysed and compared to a control group undergoing coronary artery bypass grafting (n = 10). Using immunohistochemistry, the expression of pax7, CD34 and MyoD was assessed in five sequential blinded randomly generated fields. Statistical testing of the data collected was made via the Mann Whitney U test. Protein electrophoresis was used to confirm overall protein expression of the satellite cell markers. There was a significant increase in the number of satellite cells observed in CLI muscle sections as demonstrated by the expression of pax7 (2.4×fold p < 0.0001). CD34 expressingHaematopoietic Stem Cells(HSCs) and satellite cells were also more abundant, with a 2×fold increase observed (p < 0.0001) whilst those cells expressing both CD34 and pax7 and identified as quiescent satellite cells, were significantly greater in number in the CLI samples (2.9×fold p < 0.0001), confirmed via immunohistochemistry and protein electrophoresis. There was a significant decrease in the expression of MyoD positive or activated satellite cells (p < 0.0001). This indicates an increase in the proliferation of the satellite cell population as a response to CLI but less active cells are observed.

Gutzwiller density functional theory for correlated electron systems
K. M. Ho,J. Schmalian,C. Z. Wang
Physics , 2007, DOI: 10.1103/PhysRevB.77.073101
Abstract: We develop a new density functional theory (DFT) and formalism for correlated electron systems by taking as reference an interacting electron system that has a ground state wavefunction which obeys exactly the Gutzwiller approximation for all one particle operators. The solution of the many electron problem is mapped onto the self-consistent solution of a set of single particle Schroedinger equations analogous to standard DFT-LDA calculations.
Biodegradable Polylactic Acid (PLA) Microstructures for Scaffold Applications
G. -J. Wang,K. -H. Ho,C. -C. Hsueh
Computer Science , 2008,
Abstract: In this research, we present a simple and cost effective soft lithographic process to fabricate PLA scaffolds for tissue engineering. In which, the negative photoresist JSR THB-120N was spun on a glass subtract followed by conventional UV lithographic processes to fabricate the master to cast the PDMS elastomeric mold. A thin poly(vinyl alcohol) (PVA) layer was used as a mode release such that the PLA scaffold can be easily peeled off. The PLA precursor solution was then cast onto the PDMS mold to form the PLA microstructures. After evaporating the solvent, the PLA microstructures can be easily peeled off from the PDMS mold. Experimental results show that the desired microvessels scaffold can be successfully transferred to the biodegradable polymer PLA.
Variability of organic and elemental carbon, water soluble organic carbon, and isotopes in Hong Kong
K. F. Ho, S. C. Lee, J. J. Cao, Y. S. Li, J. C. Chow, J. G. Watson,K. Fung
Atmospheric Chemistry and Physics (ACP) & Discussions (ACPD) , 2006,
Abstract: To determine the levels and variations of carbonaceous aerosol in Hong Kong, PM2.5 and PM10 samples were collected by high volume (Hi-vol) samplers at three monitoring stations (representing middle-scale roadside, urban-, and regional-scale environments) during winter (November 2000 to February 2001) and summer (June 2001 to August 2001) periods. The highest concentrations of organic carbon (OC), elemental carbon (EC), and water-soluble organic carbon (WSOC) were found at the middle-scale roadside site with the lowest at the regional-scale site. The percentages of WSOC in total carbon at these sites were inversely correlated with their concentrations (i.e., the highest percentages of WSOC were observed at the regional-scale site). A high WSOC fraction may be associated with aged aerosol because of the secondary formation by photochemical oxidation of organic precursors of anthropogenic pollutants during transport. The annual average of isotope abundances (δ13C) of OC and EC were –26.9±0.5‰ and –25.6±0.1‰, respectively. There were no notable differences for seasonal distributions of carbon isotopic composition, consistent with motor vehicle emissions being the main source contributors of carbonaceous aerosol in Hong Kong. OC 13C abundances at the regional-scale site were higher than those at the middle-scale roadside and urban sites, consistent with secondary organic aerosols of biogenic origin.
Cellular responses induced by Cu(II) quinolinonato complexes in human tumor and hepatic cells
Zdeněk Trávní?ek, Ján Van?o, Jan Ho?ek, Roman Buchtík, Zdeněk Dvo?ák
Chemistry Central Journal , 2012, DOI: 10.1186/1752-153x-6-160
Abstract: The tested complexes displayed a stronger cytotoxic effect against all the cancer cells as compared to cisplatin. The highest cytotoxicity was found for the complexes 4 (IC50?=?0.36?±?0.05?μM and 0.56?±?0.15?μM), 5 (IC50?=?0.66?±?0.07?μM and 0.73?±?0.08?μM) and 6 (IC50?=?0.57?±?0.11?μM and 0.70?±?0.20?μM) against A2780, and A2780cis respectively, as compared with the values of 12.0?±?0.8?μM and 27.0?±?4.6?μM determined for cisplatin. Moreover, the tested complexes were much less cytotoxic to primary human hepatocytes than to the cancer cells. The complexes 5 and 6 exhibited significantly high ability to modulate secretion of the pro-inflammatory cytokines TNF-α (2873?±?238?pg/mL and 3284?±?139?pg/mL for 5, and 6 respectively) and IL-1β (1177?±?128?pg/mL and 1087?±?101?pg/mL for 5, and 6 respectively) tested on the lipopolysaccharide (LPS)-stimulated THP-1 cells as compared with the values of 1173?±?85?pg/mL and 118.5?±?4.8?pg/mL found for the commercially used anti-inflammatory drug prednisone. The ability of the tested complexes to interact with sulfur-containing biomolecules (cysteine and reduced glutathione) at physiological levels was proved by electrospray-ionization mass spectrometry.Overall positive results of the biological activity studies revealed that the presented complexes may represent good candidates for non-platinum anticancer drugs, however, we are aware of the fact that further and deeper studies mainly in relation to the elucidation of their mechanisms of antiproliferative action will be necessary.One of the most important research directions in bioinorganic and medicinal chemistry is dedicated to the development of new anticancer compounds with the potential to be used either in monotherapy or in combination therapy with other approved anticancer drugs as chemosensitizers [1]. Within this scope of research, two main groups of antitumor active compounds have been developed: (a) platinum-based complexes derived from cisplatin, oxaliplatin or carbop
Incomplete melting of the Si(100) surface from molecular-dynamics simulations using the Effective-Medium Tight-Binding model
K. Stokbro K. W. Jacobsen,J. K. N?rskov,D. M. Deaven,C. Z. Wang,K. M. Ho
Physics , 1996,
Abstract: We present molecular-dynamics simulations of the Si(100) surface in the temperature range 1100-1750K. To describe the total energy and forces we use the Effective-Medium Tight-Binding model. The defect-free surface is found to melt at the bulk melting point, which we determine to be 1650 K, but for a surface with dimer vacancies we find a pre-melting of the first two layers 100 K below the melting point. We show that these findings can rationalize recent experimental studies of the high temperature Si(100) surface.
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