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Search Results: 1 - 10 of 49224 matches for " Jyun-Yi Jiang "
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CONVERTIBLE DRM SYSTEM BASED ON IDENTITY-BASED ENCRYPTION
Chou-Chen Yang,Ju-Chun Hsiao,Hung-Wen Yang,Jyun-Yi Jiang
International Journal of Computer Networks & Communications , 2009,
Abstract: With the rapid growth of the Internet, acquiring digital contents over the Internet has becomecommonplace. Most traditional items can be translated into digital form. That is to say the digitalcontents can be distributed easily and rapidly to users over the Internet. Unfortunately, situations ofpiracy are common and become more serious, since the digital contents can be copied and distributedeasily through Internet. Thus, Digital Rights Management (DRM) is a popular tool used to protect digitalcontents with cryptographic technology. But there are many different DRM encryption formats that areadopted by different content providers, causing consumers can’t play their contents on devices withdifferent DRM format even though they bought it legally. In this paper, we employ identity-basedencryption to allow a conversion between different DRM systems. Through the conversion process, thedigital content can be used at different DRM systems and hold the legitimate use of the right.
Pixel Discontinuity Repairing for Push-Broom Orthorectified Images  [PDF]
Jyun-Yi Lai, Ming-Fu Chen, Han-Chao Chang
Journal of Software Engineering and Applications (JSEA) , 2013, DOI: 10.4236/jsea.2013.64A004
Abstract:

Pixel discontinuity in orthoimages occurs frequently due to altitude variations in the pitch and heading of an airplane, and low performance of real-time analyzing software. This study proposes a scheme to resolve pixel discontinuity. The proposed scheme includes the following steps: 1) capture images by a self-made hyperspectral imager; 2) determine the pixel locations of orthoimages using a top-down approach; 3) repair discontinuities by the Nearest Neighbor (NN) or Bilinear Interpolation (BL) approaches; and, 4) perform a dynamic range adjustment on the orthoimages, according to the maximum pixel value of the raw images and orthoimages. After applying the proposed scheme, this study found that pixel discontinuity was eliminated by both approaches, and that the software dependability and image quality were improved substantially. In addition, the computational efficiency of the NN approach was roughly two minutes faster than that of the BL due to its simpler computation. However, BL produces smoother image edges for landscapes.

Classification and regression tree analysis in acute coronary syndrome patients  [PDF]
Heng-Hsin Tung, Chiang-Yi Chen, Kuan-Chia Lin, Nai-Kuan Chou, Jyun-Yi Lee, Daniel L. Clinciu, Ru-Yu Lien
World Journal of Cardiovascular Diseases (WJCD) , 2012, DOI: 10.4236/wjcd.2012.23030
Abstract: Objectives: The objectives of this study are to use CART (Classification and regression tree) and step-wise regression to 1) define the predictors of quality of life in ACS (acute coronary syndrome) patients, using demographics, ACS symptoms, and anxiety as independent variables; and 2) discuss and compare the results of these two statistical approaches. Back- ground: In outcome studies of ACS, CART is a good alternative approach to linear regression; however, CART is rarely used. Methods: A descriptive survey design was used with 100 samples recruited. Result and Conclusions: Anxiety is the most significant predictor and also a stronger predictor than symptoms of ACS for the quality of life. The anxiety level patients experienced at the time heart attack occurred can be used to predict quality of life a month later. Furthermore, the majority of ACS patients experienced a moderate to high level of anxiety during a heart attack.
Design of Compact Lowpass Filter with Ultra-Wide Stopband Using Thin Slots
Jyun-Yi Wu;Yu-Hsiang Tseng;Wen-Hua Tu
PIER C , 2012, DOI: 10.2528/PIERC12052603
Abstract: This paper presents a compact microstrip stepped-impedance lowpass filter with ultra-wide stopband by using back-to-back C-shaped and triple C-shaped thin slots. The properties of several thin slots in the ground plane have been investigated in this paper. With the full-wave simulation results and a simplified equivalent model, the total equivalent inductance of the thin slots can be extracted at cutoff frequency for lowpass filter design purpose. On the other hand, the thin slots work as bandstop filter at the stopband of the lowpass filter for a better stopband rejection. The proposed lowpass filter with a cutoff frequency of 2 GHz shows a wide stopband with an over 25-dB attenuation up to 17.5 GHz. From dc to 2 GHz, the insertion loss is less than 0.3 dB and the return loss is greater than 20 dB. In comparison to the conventional stepped-impedance lowpass filter with the same passband performance, the proposed lowpass filter shows not only a 24.3% size reduction but also a better stopband rejection.
Consumer Confidence and Stock Markets: The Panel Causality Evidence
Chih-Chiang Hsu,Hung-Yu Lin,Jyun-Yi Wu
International Journal of Economics and Finance , 2011, DOI: 10.5539/ijef.v3n6p91
Abstract: This paper uses a panel of country-level data to investigate the causal relationship between the consumer confidence index (CCI) and the stock market index (SMI). We apply the common correlated effects mean group (CCEMG) estimation of Pesaran (2006) to capture the cross-sectional dependence of our variables before examining this causal relationship. In the panel data analysis, we discover the two-way causality between the CCI and SMI. One of the ways is where stock returns Granger-cause the changes in the CCI. According to the information view of the CCI, this result is due to consumers regarding the stock returns as being the leading indicators of the future situation, regardless of whether they own the stocks or not. On the other hand, the changes in the CCI also Granger-cause the stock returns, the reason for this being attributable to the animal spirits view of consumers. When consumers believe in their own opinions, they will at the same time have strong confidence in and an optimistic attitude toward the future economic situation. Based on these conditions, consumers will invest more in the stock market.
Low-Power GaAlAs Laser Irradiation Promotes the Proliferation and Osteogenic Differentiation of Stem Cells via IGF1 and BMP2
Jyun-Yi Wu, Yan-Hsiung Wang, Gwo-Jaw Wang, Mei-Ling Ho, Chau-Zen Wang, Ming-Long Yeh, Chia-Hsin Chen
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0044027
Abstract: Low-power laser irradiation (LPLI) has been found to induce various biological effects and cellular processes. Also, LPLI has been shown to promote fracture repair. Until now, it has been unclear how LPLI promotes bone formation and fracture healing. The aim of this study was to investigate the potential mechanism of LPLI-mediated enhancement of bone formation using mouse bone marrow mesenchymal stem cells (D1 cells). D1 cells were irradiated daily with a gallium-aluminum-arsenide (GaAlAs) laser at dose of 0, 1, 2, or 4 J/cm2. The lactate dehydrogenase (LDH) assay showed no cytotoxic effects of LPLI on D1 cells, and instead, LPLI at 4 J/cm2 significantly promoted D1 cell proliferation. LPLI also enhanced osteogenic differentiation in a dose-dependent manner and moderately increased expression of osteogenic markers. The neutralization experiments indicated that LPLI regulated insulin-like growth factor 1 (IGF1) and bone morphogenetic protein 2 (BMP2) signaling to promote cell proliferation and/or osteogenic differentiation. In conclusion, our study suggests that LPLI may induce IGF1 expression to promote both the proliferation and osteogenic differentiation of D1 cells, whereas it may induce BMP2 expression primarily to enhance osteogenic differentiation.
Low-Power Laser Irradiation Suppresses Inflammatory Response of Human Adipose-Derived Stem Cells by Modulating Intracellular Cyclic AMP Level and NF-κB Activity
Jyun-Yi Wu, Chia-Hsin Chen, Chau-Zen Wang, Mei-Ling Ho, Ming-Long Yeh, Yan-Hsiung Wang
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0054067
Abstract: Mesenchymal stem cell (MSC)-based tissue regeneration is a promising therapeutic strategy for treating damaged tissues. However, the inflammatory microenvironment that exists at a local injury site might restrict reconstruction. Low-power laser irradiation (LPLI) has been widely applied to retard the inflammatory reaction. The purpose of this study was to investigate the anti-inflammatory effect of LPLI on human adipose-derived stem cells (hADSCs) in an inflammatory environment. We showed that the hADSCs expressed Toll-like Receptors (TLR) 1, TLR2, TLR3, TLR4, and TLR6 and that lipopolysaccharide (LPS) significantly induced the production of pro-inflammatory cytokines (Cyclooxygenase-2 (Cox-2), Interleukin-1β (IL-1β), Interleukin-6 (IL-6), and Interleukin-8 (IL-8)). LPLI markedly inhibited LPS-induced, pro-inflammatory cytokine expression at an optimal dose of 8 J/cm2. The inhibitory effect triggered by LPLI might occur through an increase in the intracellular level of cyclic AMP (cAMP), which acts to down-regulate nuclear factor kappa B (NF-κB) transcriptional activity. These data collectively provide insight for further investigations of the potential application of anti-inflammatory treatment followed by stem cell therapy.
Validation of Type 2 Diabetes Risk Variants Identified by Genome-Wide Association Studies in Han Chinese Population: A Replication Study and Meta-Analysis
Yi-Cheng Chang, Pi-Hua Liu, Yu-Hsiang Yu, Shan-Shan Kuo, Tien-Jyun Chang, Yi-Der Jiang, Jiun-Yi Nong, Juey-Jen Hwang, Lee-Ming Chuang
PLOS ONE , 2014, DOI: 10.1371/journal.pone.0095045
Abstract: Background Several genome-wide association studies (GWAS) involving European populations have successfully identified risk genetic variants associated with type 2 diabetes mellitus (T2DM). However, the effects conferred by these variants in Han Chinese population have not yet been fully elucidated. Methods We analyzed the effects of 24 risk genetic variants with reported associations from European GWAS in 3,040 Han Chinese subjects in Taiwan (including 1,520 T2DM cases and 1,520 controls). The discriminative power of the prediction models with and without genotype scores was compared. We further meta-analyzed the association of these variants with T2DM by pooling all candidate-gene association studies conducted in Han Chinese. Results Five risk variants in IGF2BP2 (rs4402960, rs1470579), CDKAL1 (rs10946398), SLC30A8 (rs13266634), and HHEX (rs1111875) genes were nominally associated with T2DM in our samples. The odds ratio was 2.22 (95% confidence interval, 1.81-2.73, P<0.0001) for subjects with the highest genetic score quartile (score>34) as compared with subjects with the lowest quartile (score<29). The incoporation of genotype score into the predictive model increased the C-statistics from 0.627 to 0.657 (P<0.0001). These estimates are very close to those observed in European populations. Gene-environment interaction analysis showed a significant interaction between rs13266634 in SLC30A8 gene and age on T2DM risk (P<0.0001). Further meta-analysis pooling 20 studies in Han Chinese confirmed the association of 10 genetic variants in IGF2BP2, CDKAL1, JAZF1, SCL30A8, HHEX, TCF7L2, EXT2, and FTO genes with T2DM. The effect sizes conferred by these risk variants in Han Chinese were similar to those observed in Europeans but the allele frequencies differ substantially between two populations. Conclusion We confirmed the association of 10 variants identified by European GWAS with T2DM in Han Chinese population. The incorporation of genotype scores into the prediction model led to a small but significant improvement in T2DM prediction.
SLC2A10 genetic polymorphism predicts development of peripheral arterial disease in patients with type 2 diabetes. SLC2A10 and PAD in type 2 diabetes
Yi-Der Jiang, Yi-Cheng Chang, Yen-Feng Chiu, Tien-Jyun Chang, Hung-Yuan Li, Wen-Hsing Lin, Hsiang-Yu Yuan, Yuan-Tsong Chen, Lee-Ming Chuang
BMC Medical Genetics , 2010, DOI: 10.1186/1471-2350-11-126
Abstract: We genotyped 10 single nucleotide polymorphisms and one microsatellite spanning 34 kb across the SLC2A10 gene in a prospective cohort of 372 diabetic patients. Their association with the development of peripheral arterial disease (PAD) in type 2 diabetic patients was analyzed.At baseline, several common SNPs of SLC2A10 gene were associated with PAD in type 2 diabetic patients. A common haplotype was associated with higher risk of PAD in type 2 diabetic patients (haplotype frequency: 6.3%, P = 0.03; odds ratio [OR]: 14.5; 95% confidence interval [CI]: 1.3- 160.7) at baseline. Over an average follow-up period of 5.7 years, carriers with the risk-conferring haplotype were more likely to develop PAD (P = 0.007; hazard ratio: 6.78; 95% CI: 1.66- 27.6) than were non-carriers. These associations remained significant after adjustment for other risk factors of PAD.Our data demonstrate that genetic polymorphism of the SLC2A10 gene is an independent risk factor for PAD in type 2 diabetes.Peripheral arterial disease (PAD), defined as lower extremity arterial atherosclerosis, is one of most common diseases of the arteries and is a major complication of type 2 diabetes [1]. Conventional cardiovascular risk factors such as aging, smoking, hyperglycemia, hypertension and dyslipidemia have been shown to be associated with PAD [1]. However, the increased risk for atherosclerotic diseases in diabetic patients can be only partially explained by the conventional risk factors [2]. In fact, a high heritability for ankle-brachial blood pressure index (ABI), an index of PAD, has been obtained in Twin studies in Caucasians [3], indicating that additional genetic factors might be involved in the pathogenesis of PAD. In this respect, the search for genetic causes of PAD remains limited [4].Recently, a genetic form of arterial tortuosity syndrome (ATS; OMIM 208050) was reported to be caused by loss-of-function mutations in the SLC2A10 gene encoding the facilitative glucose transporter GLUT10. A
Exploring the Environmental Physiology of the Indo-Pacific Reef Coral Seriatopora hystrix with Differential Proteomics  [PDF]
Anderson B. Mayfield, Yi-Jyun Chen, Chi-Yu Lu, Chii-Shiarng Chen
Open Journal of Marine Science (OJMS) , 2018, DOI: 10.4236/ojms.2018.82012
Abstract:
Although reef-building corals are threatened by a number of anthropogenic impacts, certain scleractinian-dinoflagellate (genus Symbiodinium) endosymbioses have proven markedly resilient to environmental change. For instance, corals from upwelling habitats of Southern Taiwan withstand both short- and long-term increases in temperature, potentially due to their routine exposure to highly variable temperature regimes in situ. To gain a greater understanding of the proteomic basis for such acclimatization to unstable environmental conditions, specimens of the Indo-Pacific reef-building coral Seriatopora hystrix Dana 1846 were sampled during a period of stable temperature conditions from 1) a site characterized by frequent upwelling events in Southern Taiwan and 2) a nearby, non-upwelling control site in the Taiwan Strait. Two-dimensional gel electrophoresis followed by sequencing of differentially concentrated proteins with mass spectrometry unveiled significantly more proteins involved in the cellular stress response in coral hosts of the upwelling site. Although such stress protein signatures could be indicative of sub-lethal levels of cellular stress, especially given the relatively higher sediment loads characteristic of the upwelling site, these proteins may, in contrast, have been constitutively maintained at high levels in preparation for large fluctuations in temperature and other abiotic parameters (e.g., nutrient levels) brought upon by upwelling events.
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