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Search Results: 1 - 10 of 464148 matches for " Julie A. LaComb "
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Spoke Top Antenna for Transient Radiation
Julie A. LaComb
PIER Letters , 2009, DOI: 10.2528/PIERL09080602
Abstract: When an antenna transmits a short pulse of energy such as used for ultra-wide band applications, the pulse gets distorted upon transmission. To examine the properties of pulse transmission it is helpful to analyze the system in the time domain versus the frequency domain. Presented is a spoke top antenna for transient radiation. The spokes reduce the reflection from the open end of the antenna significantly reducing the trailing pulses commonly seen in the time domain. Comparisons are made with a dipole antenna. Both analytical, modeled and experimental results are presented.
Ultra Wideband Surface Wave Communication
Julie A. LaComb;Paul M. Mileski;Raymond F. Ingram
PIER C , 2009, DOI: 10.2528/PIERC09042701
Abstract: Ultra Wideband (UWB), an impulse carrier waveform, was applied at HF-VHF frequencies to utilize surface wave propagation. Due to the low duty cycle of the pulse, the energy requirements are significantly reduced. UWB involves the propagation of transient pulses rather than continuous waves which makes the system easier to implement, inexpensive and small. The use of surface wave propagation (instead of commercial SHF UWB) extends the communication range. The waveform, transmitter, receiver, modulation and channel characteristics of the novel system design will be presented.
Alterations of the extracellular matrix in ovarian cancer studied by Second Harmonic Generation imaging microscopy
Oleg Nadiarnykh, Ronald B LaComb, Molly A Brewer, Paul J Campagnola
BMC Cancer , 2010, DOI: 10.1186/1471-2407-10-94
Abstract: For this investigation we use Second Harmonic Generation (SHG) imaging microcopy to study changes in the structure of the ovarian ECM in human normal and malignant ex vivo biopsies. This method directly visualizes the type I collagen in the ECM and provides quantitative metrics of the fibrillar assembly. To quantify these changes in collagen morphology we utilized an integrated approach combining 3D SHG imaging measurements and bulk optical parameter measurements in conjunction with Monte Carlo simulations of the experimental data to extract tissue structural properties.We find the SHG emission attributes (directionality and relative intensity) and bulk optical parameters, both of which are related to the tissue structure, are significantly different in the tumors in a manner that is consistent with the change in collagen assembly. The normal and malignant tissues have highly different collagen fiber assemblies, where collectively, our findings show that the malignant ovaries are characterized by lower cell density, denser collagen, as well as higher regularity at both the fibril and fiber levels. This further suggests that the assembly in cancer may be comprised of newly synthesized collagen as opposed to modification of existing collagen.Due to the large structural changes in tissue assembly and the SHG sensitivity to these collagen alterations, quantitative discrimination is achieved using small patient data sets. Ultimately these measurements may be developed as intrinsic biomarkers for use in clinical applications.In 2008, there were an estimated 21,650 new cases of ovarian cancer in the United States and 15,520 deaths (Cancer Facts and Figures 2008, American Cancer Society, Database). Little is currently known about markers of premalignancy, early malignancy or early pathways for malignancy that could be potentially manipulated for prevention or early detection of ovarian cancer. Additionally, it is recognized that malignant cells with a specific and identifyi
Effects of Fructooligofructoses Chain Length on the Bifidobacteria of the Human Colon: A Pilot Study  [PDF]
Krista Mendlik, Julie A. Albrecht, Marilynn Schnepf
Food and Nutrition Sciences (FNS) , 2012, DOI: 10.4236/fns.2012.312211
Abstract: Human gastrointestinal health may be improved by the consumption of prebiotic food ingredients such as fructooligo-fructoses. A study was initiated to determine the effect of fructooligofructoses of different chain lengths on gastrointes-tinal parameters. Nineteen healthy subjects aged 20 - 57 y took part in a 10-week cross-over designed study. Subjects consumed either inulin or oligofructose for 3 weeks followed by a 2-week washout period between treatments. Stool samples were collected five times (baseline, 2 treatments, 2 washout) and analyzed for bifidobacteria. Daily records were kept for stool frequency, stool consistency and flatulence frequency. Bifidobacteria counts (cfu/ml) were higher (trending toward significance) during inulin and oligofructose intakes (1.2 × 107 ± 4.8 × 107 and 2.0 × 108 ± 4.7 × 108) and washout periods (2.9 × 106 ± 6.5 × 106 and 1.1 × 107 ± 1.6 × 107) than baseline counts (2.2 × 105 ± 5.1 × 105 and 2.9 × 106 ± 6.5 × 106), respectively. Inulin and oligofructose treatment periods had a significant effect on stool consistency (watery/very hard) and flatulence frequency, but not stool frequency, when compared to baseline (P < 0.05). Further research is needed to confirm these results due to small sample size and the need for a longer washout period between treatments.
A Novel Combined Approach for Metastatic Breast Cancer with Dural and Leptomeningeal Disease with an Impressive Clinical Outcome: A Case Study  [PDF]
Julie Taguchi, Christopher Duma, M. A. Nezami
Journal of Cancer Therapy (JCT) , 2018, DOI: 10.4236/jct.2018.93025
Abstract: Concurrent dural and leptomeningeal metastatic carcinomatosis are very rare and have a poor prognosis. Here we present a woman with advanced estrogen receptor (ER) positive and progesterone receptor (PR) positive breast cancer who presented with leptomeningeal disease. Patient underwent multi targeted epigenetic therapies applied in a protocol called MTET. She continued to respond to the interval treatment, which consisted only of the nutraceutical agents. Here we discuss her case in detail and we believe that such an example might be applied to other patients in this situation resulting clinical improvement and less toxicity.
Response shift and glycemic control in children with diabetes
Julie A Wagner
Health and Quality of Life Outcomes , 2005, DOI: 10.1186/1477-7525-3-38
Abstract: At year 1, thirty-eight children with type 1 diabetes attending a diabetes summer camp participated. At baseline and post-camp they completed the Problem Areas in Diabetes (PAID) questionnaire. Post-camp, the PAID was also completed using the 'thentest' method, which requires a retrospective judgment about their baseline functioning. At year 2, fifteen of the original participants reported their HbA1c.PAID scores significantly decreased from baseline to post-camp. An even larger difference was found between thentest and post-camp scores, suggesting scale recalibration. There was a significant positive correlation between year 1 HbA1c and thentest scores. Partial correlation analysis between PAID thentest scores and year 2 HbA1c, controlling for year 1 HbA1c, showed that higher PAID thentest scores were associated with higher year 2 HbA1c.Results from this small sample suggest that children with diabetes do show scale recalibration, and that it may be related to glycemic control.Diabetes is one of the most common chronic diseases of childhood. Adjustment to the disease and the demands of its complex regimen are formidable tasks even for adults. Children face these demands in the context of already challenging normative developmental tasks. Understanding children's diabetes-related problems can inform intervention designed to improve medical outcomes and quality of life for this population.Response shift is a theoretical construct that provides a framework for this investigation. In essence, it posits that people can adjust how they think about their quality of life when they encounter relevant new information. In this model, antecedents (e.g., demographics, personality), interact with a catalyst (intervention or change in health status) to elicit psychological mechanisms (e.g., social comparison) in order to accommodate the catalyst. Response shift then influences one's quality of life evaluation (see figure 1). According to Schwartz & Sprangers [1], response shift p
L'Américanisme fran?ais au début du XXème siècle: projets politiques, muséologie et terrains brésiliens
Cavignac, Julie A.;
Vibrant: Virtual Brazilian Anthropology , 2012, DOI: 10.1590/S1809-43412012000100002
Abstract: this article aims to evaluate the importance of americanist studies and the place of french researchers in the constitution of an international research network in the early 20th century. we try to understand how this disciplinary field emerged centered on the native american people, especially their cultural and social specificities. an analysis of the methodological underpinnings of the first collections reveals that special attention was given to the collection and the study of material culture since it bore witness to the diversity of human societies. young collaborators were hired to be in charge of and to analyze the collection of objects for the musée de l'homme in order to fill the lacuna of knowledge of the "native americans cultures". lévi-strauss' two missions (1935 and 1938) to make the inventory of the material culture that were part of this project inaugurated a new phase of americanist studies, focussed on the study of social structure. we evaluate the importance of this change for americanist research in the amazon and the consolidation of an international research network that came into being prior to the second world war. such a documental review, which questions the 'museologized' ethnographic object, is important because it allows us to reread the history of the discipline, in the light of the importance of the historical contexts, political debates and the place of americanist studies in brazil and in france. it is also possible to define the limits of an anthropology which becomes autonomous and takes a critical position in relation to colonial states and welfare services provided to native americans.
The Situated Nature of Virtual Teamwork: Understanding the Constitutive Role of
Julie A. Rennecker
Sprouts : Working Papers on Information Systems , 2002,
Abstract: The time-space configurations of place and space are used to ground an analysis and discussion of the constitutive role of place, or virtual team members' respective local contexts, in the conduct of virtual teamwork. In contrast to the majority of current virtual teams research, which emphasizes the "spatial," or virtual aspect of virtual teamwork, this study uses an extended example, the establishment of a computer-conferencing infrastructure, to show the constitutive role played by local institutionalized rhythms, relationships, rules, politics, and resources in the enactment of virtual team tasks. Implications for studying, designing, and managing virtual teams are discussed.
Motivational Interviewing Step By Step
Julie A. Schumacher, PhD
Motivational Interviewing : Training, Research, Implementation, Practice , 2013, DOI: 10.5195/mitrip.2013.37
Abstract: N/A
Is Economics a Natural Science?
Julie A. Nelson
Cosmos and History : the Journal of Natural and Social Philosophy , 2006,
Abstract: Advocates of a more socially responsible discipline of economics often emphasize the purposive and unpredictable nature of human economic behavior, contrasting this to the presumably deterministic behavior of natural forces. This essay argues that such a distinction between “social” and “natural” sciences is in fact counterproductive, especially when issues of ecological sustainability are concerned. What is needed instead is a better notion of science—“science-with-wonder”—which grounds serious science in relational, non-Newtonian thinking.
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