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Search Results: 1 - 10 of 120315 matches for " Jue Wang "
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The Impact of Radical Prostatectomy on the Survival of Patients with Carcinosarcoma of the Prostate  [PDF]
Jue Wang, Fenwei Wang
Journal of Cancer Therapy (JCT) , 2011, DOI: 10.4236/jct.2011.24064
Abstract: Background: The objective of this study was to evaluate the impact of radical prostatectomy on carcinosarcoma of the prostate. Methods: Patients diagnosed with carcinosarcoma of the prostate from 1977 through 2007 were identified in the Surveillance, Epidemiology, and End Results (SEER) database. Outcomes were examined with Kaplan-Meier survival analysis and Cox models. The association between clinical and demographic characteristics and survival of carcinosarcoma of the prostate was examined. Results: A total of fifty-four cases of histology confirmed carcinosarcoma of the prostate were identified. Median age of the patients was 74 years (range 28 - 94). Of the patients with a known tumor stage, all but one patient had a locally advanced or distant stage; all of the patients with known histology grade had poorly or undifferentiated histology. Twenty (37%) patients underwent transurethral resection only and Fourteen (25.9%) patients underwent radical prostatectomy. Eight (14%) patients received radiation therapy in combination with surgery. The median cancer specific survival was 16 months (95% CI 0 - 32 months). 1-, 3-, and 5- year cancer specific survival rate were 55.1%, 32.3% and 21.1%. In a multivariate analysis, radical prostatectomy was found to be a significant prognostic factor for cancer-specific survival. Conclusions: Carcinosarcoma of the prostate commonly occurs in older patients and associated with aggressive disease and poor prognosis. Radical prostatectomy is the only treatment modality that significantly improves survival. Emphasis on early diagnosis and detection and multimodality therapy of this disease is needed to improve the outcome for patients with this malignancy.
The Asymptotic Eigenvalues of First-Order Spectral Differentiation Matrices  [PDF]
Jue Wang, Fabian Waleffe
Journal of Applied Mathematics and Physics (JAMP) , 2014, DOI: 10.4236/jamp.2014.25022
Abstract: We complete and extend the asymptotic analysis of the spectrum of Jacobi Tau approximations that were first considered by Dubiner. The asymptotic formulas for Jacobi polynomials PN(α ,β ) ,α ,β > -1 are derived and confirmed by numerical approximations. More accurate results for the slowest decaying mode are obtained. We explain where the large negative eigenvalues come from. Furthermore, we show that a large negative eigenvalue of order N2 appears for -1 <α < 0 ; there are no large negative eigenvalues for collocations at Gauss-Lobatto points. The asymptotic results indicate unstable eigenvalues for α > 1 . The eigenvalues for Legendre polynomials are directly related to the roots of the spherical Bessel and Hankel functions that are involved in solving Helmholtz equation inspherical coordinates.
Bayes-Optimal Sequential Multi-Hypothesis Testing in Exponential Families
Jue Wang
Statistics , 2015,
Abstract: Bayesian sequential testing of multiple simple hypotheses is a classical sequential decision problem. But the optimal policy is computationally intractable in general, because the posterior probability space is exponentially increasing in the number of hypotheses (i.e, the curse of dimensionality in state space). We consider a specialized problem in which observations are drawn from the same exponential family. By reconstructing the posterior probability vector using the natural sufficient statistic, it is shown that the intrinsic dimension of the posterior probability space cannot exceed the number of parameters governing the exponential family, or the number of hypotheses, whichever is smaller. For univariate exponential families commonly used in practice, the probability space is of one or two dimension in most cases. Hence, the optimal policy can be attainable with only moderate computation. Geometric interpretation and illustrative examples are presented. Simulation studies suggest that the optimal policy can substantially outperform the existing method. The results are also extended to the sequential sampling control problem.
Classification of Indecomposable Flows of Signed Graphs
Beifang Chen,Jue Wang
Mathematics , 2011,
Abstract: An indecomposable flow $f$ on a signed graph $\Sigma$ is a nontrivial integral flow that cannot be decomposed into $f=f_1+f_2$, where $f_1,f_2$ are nontrivial integral flows having the same sign (both $\geq 0$ or both $\leq 0$) at each edge of $\Sigma$. This paper is to classify indecomposable flows into characteristic vectors of circuits and Eulerian cycle-trees --- a class of signed graphs having a kind of tree structure in which all cycles can be viewed as vertices of a tree. Moreover, each indecomposable flow other than circuit characteristic vectors can be further decomposed into a sum of certain half circuit characteristic vectors having the same sign at each edge. The variety of indecomposable flows of signed graphs is much richer than that of ordinary unsigned graphs.
Refusal of Cancer-Directed Surgery Strongly Impairs Survival of Patients with Localized Hepatocellular Carcinoma
Jue Wang,Fen Wei Wang
International Journal of Surgical Oncology , 2010, DOI: 10.1155/2010/381795
Abstract: Background: This study investigated the frequency of patients with HCC who refused cancer-directed surgery and the characteristics and outcomes of these patients. Patients and Methods: A retrospective study was performed using data from the Surveillance, Epidemiology, and End Results (SEER) Program. Characteristics of patients who refused CDS were compared with those who accepted surgery using logistic regression. The effect of refusing CDS on mortality was evaluated by Cox proportional hazards analysis. Results: Among 4373 surgical candidates, 142 patients (3.2%) refused the recommended CDS. The patients who refused CDS were frequently older, African American, widowed or divorced, and had advanced-stage tumors. In a logistic regression analysis, older age, African American, and being divorced or widowed were independently associated with refusal of CDS. After adjusting for other patient and tumor characteristics, the patients who refused CDS had a 2.5-fold (95% confidence interval, 2.339–3.189) higher risk of dying from HCC in comparison with patients who had CDS. Conclusions: The high rate of refusal may contribute in part to the disparity in utilization of CDS. Of greatest concern is that the patients who declined CDS had an impaired survival. This information might be helpful for patients to make a better-informed decision. 1. Introduction Hepatocellular carcinoma (HCC) is the most frequent primary liver cancer. The annual number of new cases worldwide is approximately 550,000, representing more than 5% of human cancers and the third leading cause of cancer-related deaths [1, 2]. The goal of cancer-directed surgery (CDS) is to completely remove localized tumors or reduce the size of large tumors. CDS includes the curative surgeries (such as hepatectomy and transplantation) and local regional therapy, which employ modern surgical tools (including laser, high-frequency electrical currents, radiation, and liquid nitrogen), sometimes in conjunction with alcohol or chemotherapy agents. Resection and transplantation offer the best chance of long-term, disease-free survival and overall survival for patients with HCC. In a large series of patients from specialty institutions, the median survival of those who underwent resection of HCC lesions has ranged from 30 to 70 months [2–6]. Local regional therapy can provide alternatives for patients who are not candidate for resection or transplantation. Recently, chemoembolation has demonstrated survival benefits [7–11]. The 5-year survival rates for patients who underwent surgery, transhepatic arterial
Game-Theoretic Analysis of Renouncing Membership of a Party to Announce Candidacy  [PDF]
Jue-Shyan Wang, Mei-Yin Lin
Modern Economy (ME) , 2012, DOI: 10.4236/me.2012.35084
Abstract: A game model is established to analyze the interaction in strategy when there is a candidate who renounces membership of a party to run for a position. We use the Bayesian Nash equilibrium and sequential equilibrium to discuss two models in which the candidate without nominations moves first or the decision maker of the other party moves first respectively. The main finding is that the equilibrium strategy of the decision maker of the other party is identical when the opponent runs for a position, regardless of who moving first. However, the probability of the candidate without nomination to run for a position is larger when he moves first.
The Impact of Different Antitrust Laws on the Actions of Cartels  [PDF]
Jue-Shyan Wang, Yi-Shao Chen
Theoretical Economics Letters (TEL) , 2012, DOI: 10.4236/tel.2012.25085
Abstract: The issues about antitrust laws are getting much attention nowadays. And many countries over the world adopt leniency policies to control the actions of cartels. We used a game-theoretical model to discuss the equilibrium of cartels under different antitrust laws. And we modify the model of Blum et al. [1] to analyze the equilibriums of firms under the different mechanisms of leniency policies. We find out that the value of fine will affect the existence of a cartel, and the recognitions of legitimacies for cartels are important as well. When the antitrust authorities ask firms to propose appliances in advance to let the cartels be legal, firms would incline not to become a cartel. It’s quite different from the other mechanism which firms can confess to the antitrust authorities after they’ve already become a cartel.
Analysis on attribute reduction strategies of rough set
Analysis on Attribute Reduction Strategies of Rough Set

Wang Jue,and Miao Duoqian,
Wang Jue
,Miao Duoqian

计算机科学技术学报 , 1998,
Abstract: Several strategies for the minimal attribute reduction with polynomial time complexity (O(nk)) have been developed in rough set theory. Are they complete? While investigating the attribute reduction strategy based on the discernibility matrix (DM),a counterexample is constructed theoretically, which demonstrates that these strategies are all incomplete with respect to the minimal reduction.
Outcome of Combined Hepatocellular and Cholangiocarcinoma of the Liver
Jue Wang,Fenwei Wang,Anne Kessinger
Journal of Oncology , 2010, DOI: 10.1155/2010/917356
Abstract: Background. The objective of this study was to examine the epidemiology, natural history, and prognostic factors of combined hepatocellular and cholangiocarcinoma (cHCC-CC) using population-based registry. Methods. The Surveillance, Epidemiology, and End Results Program database (1973–2004) was used to identify cases of cHCC-CC. Multivariable logistic regression was used to evaluate factors associated with cancer-directed surgery (CDS). The influence of CDS on cancer specific survival was evaluated using Kaplan-Meier curves and Cox proportional hazards modeling. Results. A total of 380 cases of cHCC-CC were identified, which account for approximately 0.87% of primary liver tumors. Of all patients, 69.8% of patients had regional or distant stage; 65.6% of patients had poorly or undifferentiated histology. Only 44.9% of patients with localized disease, received CDS. By logistic regression analysis, being widowed, advanced stage, and earlier diagnosis year were associated with lower rate of utilization of CDS. In multivariate analysis, tumor stage, receipt of CDS, and recent year of diagnosis were found to be significant predictors for cancer-specific survival. Conclusions. Patients with localized cHCC-CC who are selected for CDS were strongly associated with improved survival. However, many patients with localized tumors did not receive potentially curative cancer-directed surgery. Further study is warranted to address the barriers to the delivery of appropriate care to these patients. 1. Introduction Combined hepatocellular and cholangiocarcinoma (cHCC-CC) is an uncommon subtype of primary liver cancer [1, 2]. The disease was first described in 1949 by Allen and Lisa and has been defined as the intimate intermingling of both a HCC component and CC component Two histopathological classification schemes have been proposed Allen and Lisa [1] described three groups, type A with HCC and CC present at different sites within the same liver, and type B with HCC and CC present at adjacent sites and mingle with continued growth, and type C with HCC and CC are combined in the same tumor. Goodman et al. [2] categorized cHCC-CC into three types: collision type, transitional type, and fibrolamellar type. Kim et al. [3] and Zhang et al. [4] proposed that cHCC-CC is a distinct type of primary liver carcinoma, which is morphologically and phenotypically intermediate between HCC and CC and may be derived from hepatic progenitor cells with the bipotential to differentiate into both hepatocytic and cholangiocytic lineages. Because of the rarity of cHCC-CC, previously
The Natural History and Outcomes of the Patients with Carcinosarcoma Involving Kidney and Renal Pelvis
Jue Wang,Fen Wei Wang,Anne Kessinger
Advances in Urology , 2011, DOI: 10.1155/2011/693964
Abstract: Background. The objective of this paper was to examine the epidemiology, natural history, and prognostic factors of carcinosarcoma of the kidney and renal pelvis (CSKP) using population-based registry. Patients and Methods. Forty-three patients with CSKP, diagnosed between January 1973 and December 2007, were identified from the national Surveillance, Epidemiology, and End Results (SEER) database and reviewed. Results. 79% of all patients with known SEER stage were classified as having regional or distant stage; almost all the patients with known histology grade had poorly or undifferentiated histology. The median cancer specific survival was 6 months (95% CI 4–9). The 1-year cancer-specific survival rate for entire cohort was 30.2%. There were no differences in terms of age at diagnosis, histological grade, tumor stage on presentation, and frequency of nephrectomy between carcinosarcoma of kidney (CSK) or renal pelvis (CSP). In multivariate analysis, age at diagnosis, tumor stage, and year of diagnosis were found to be significant predictors for cancer-specific survival. Conclusion. CSKP commonly presented as high-grade, advanced stage disease, and was associated with a poor prognosis regardless of location. 1. Background Carcinosarcoma (CS) is a highly aggressive tumor composed of mixed malignant epithelial and mesenchymal components [1]. Carcinosarcoma of the kidney or renal pelvis (CSKP) is a rare malignancy of the genitourinary system. To date, fewer than 20 well-documented cases have been reported in the medical literature [2–10]. Most of the reported cases were carcinosarcoma of the renal pelvis (CSP) [2, 4–9]; only few cases were from kidney (CSK) [3, 10]. The histogenesis of carcinosarcomas remains a matter of controversy [3, 5, 8, 11]. Two main mechanisms were suggested: the “collision” or “multiclonal” hypothesis posits that the epithelial and mesenchymal components are distinct coexisting populations with different cells of origin [3]. The alternative “monoclonal” hypothesis suggests that carcinosarcoma arises from a single multipotent stem cell that differentiates along epithelial and mesenchymal pathways [11]. Due to the rareness of the disease, current literature on carcinosarcoma of the genitourinary system predominantly consists of a single case report and histopathological studies [2–10], the demographic features and clinical behavior of these tumors remain ill-defined; in addition, the survival of CSK and CSP was never directly compared. In this study, a comprehensive analysis was performed to examine the epidemiology, natural
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