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Search Results: 1 - 10 of 127488 matches for " Jue Li "
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Nonzero Solutions of Generalized Variational Inequalities  [PDF]
Jue Li, Yisheng Lai
Applied Mathematics (AM) , 2010, DOI: 10.4236/am.2010.11010
Abstract: The existence of nonzero solutions for a class of generalized variational inequalities is studied by ?xed point index approach for multivalued mappings in ?nite dimensional spaces and re?exive Banach spaces. Some new existence theorems of nonzero solutions for this class of generalized variational inequalities are established.
On Hadamard-type Inequalities for s-Preinvex Functions
LI Jue-you
Journal of Chongqing Normal University , 2010,
Abstract: In recent years, various refinements of the classical Hadamard inequalities for the convex functions and its variant forms are obtained in the literature by many researchers. At the same time, several refinements and variant forms of the Hadamard-type inequalities for s-convex functions as a generalization of convex functions, are also derived. The objective of this paper is to obtain several new Hadamard-type inequalities about s-preinvex functions. A new kind of generalized convex functions, termed s-preinvex functions in the second sense is introduced through relaxing the concept of s-convex functions. And the Hadamard-type inequalities for s-preinvex functions are established under certain conditions, i.e. let * be an invex set with respect to n. Assuming that * is an s-preinvex function in *, then for some fixe s *, where n satisfies the well-known condition * for the first inequality in the above inequalities. With Kinmaci's two new Hadamard-type inequalities for products of convex and s-convex functions, two new Hadamard-type inequalities for products of two s-preinvex functions are obtained. These results generalize some known results and include the previous known conclusions for s-convex as special case. (* Indicates a formula, please see the full text)
Effect of Biejiajian Oral Liquid on the Expression of RAAS in Hepatic Fibrosis Rats  [PDF]
Li Yao, Yun-Long Zhang, Jue Li, Jing Yu, Yan Peng
Pharmacology & Pharmacy (PP) , 2012, DOI: 10.4236/pp.2012.33043
Abstract: Objective: To study the effect of Biejiajian Oral Liquid (BOL) on the rennin angiotensin aldosterone system (RAAS) in plasma of hepatic fibrosis rats and in hepatic stellate cell (HSC) of normal rats. We explore the mechanism of BOL on inhibiting the activation of HSC and illustrate its mechanism of anti-hepatic fibrosis further. Methods: SD Rats were divided into 5 groups randomly: normal control group, model group, Enalapril group and BOL groups with different concentration (2.0 g/ml or 1.0 g/ml). Every group was administered with CCl4 and olive oil solution to induce hepatic fibrosis except normal one. Each group was treated with the respective drug for 5 weeks and then got the blood. The level of renin, angiotensin II and aldosterone in the plasma of liver fibrosis rats were detected by the radioimmunoassay. By using reverse transcription-polymerase chain reaction (RT-PCR) to measure the gene expression of the rennin, ACE, angiotensinogen, AT1R and ALD. The AT1R gene expression in normal HSC was determined by the immunohistochemical measurement. Results: BOL could effectively reduce the activity of the PRA, AngIIand ALD, which showed a significant effect on the inhibition of the AngII (P < 0.01). Meanwhile, compared with the normal control group, there was a notable inhibitory action on the PRA of HSC which was administrated by serum containing BOL (P < 0.05). And yet, drug applied group showed no difference with the model group for other factors of the RAAS. Conclusion: BOL can inhibit the expression of RAAS in the rat plasma and can inhibit the expression of the mRNA of renin in the normal HSC, which could be the mechanism of anti-hepatic fibrosis.
The Value of Music in Children’s Enlightenment Education  [PDF]
Jue Zhou
Open Journal of Social Sciences (JSS) , 2015, DOI: 10.4236/jss.2015.312023
Abstract: A large number of theories and experiments have shown that music plays positive effect on children’s growth. Children who have received music education often show outstanding creativity and imagination in their school lives, compared with their peers who have not get any musical training. Just as famous educator Dr. Hans Gunther Bastian has once proposed: “music makes people smart”. Learning music can not only improve children’s intelligence and morality which contributes to the development of their personality, but also can improve their aesthetic ability. Cultivate music to children is an essential progress to promote all-ground education.
An Empirical Analysis to the Impact of Tax Incentives on FDI after WTO  [PDF]
Jue Yan
Modern Economy (ME) , 2016, DOI: 10.4236/me.2016.711121
Abstract: Based on 36 cities’ datum, We build a model to examine whether a series of tax incentives to promote FDI inflows have a significant effect or not after 2001. The results showed that: After WTO, preferential tax policies which were taken to promote FDI inflows and upgrade industrial structure indeed had a certain effect. From sub-regional perspective, preferential tax policies for central and western regions still attract FDI, while the eastern region is no longer significant.
The influence of anthracosis and p16ink4a gene abberant methylation to the oncogenesis and progression of small pulmonary adenocarcinoma
Daye WANG,Jue WANG,Yong LI
Chinese Journal of Lung Cancer , 2008,
Abstract: Background and objective Anthracosis is black dust matter deposition in the pulmonary parenchyma, which can cause bronchial deformity and destruction. Previously reported, anthracosis is closely correlated to the oncogenesis and progression of small pulmonary adenocarcinoma and p16ink4a gene aberrant methylation was closely associated with lung carcinogenesis. In this study, we want to characterize the influence of anthracosis and p16ink4a gene aberrant methylation on small adenocarcinoma. Methods DNA was bisulfite modified and then Methylation Specific PCR was used to detect p16ink4a gene aberrant methylation, and black dust matter was extracted from lung tissues, the absolute absorbance (A) detected by densitometry was defined as anthracotic index (AI). The histopathologic diagnosis was according to Noguchi's classification for small pulmonary adenocarcinoma. Results For heavy smokers, the mean AI was significantly higher than that of nonsmokers (P=0.005) and the frequency of p16ink4a gene aberrant methylation was also significantly higher than that of nonsmokers (P=0.023). The frequency of p16ink4a gene aberrant methylation of early stage small adenocarcinoma was lower than that of advanced and poor differentiated small adenocarcinoma, otherwise p16ink4a protein expression of early stage small adenocarcinoma was significantly higher than that of poor differentiated small adenocarcinoma (P=0.032). Conclusion AI and p16ink4a gene aberrant methylation detection could be used as a combined potential biomarker of small adenocarcinoma.  
An Efficient Weighted Graph Strategy to Identify Differentiation Associated Genes in Embryonic Stem Cells
Jie Zhang, Li Li, Luying Peng, Yingxian Sun, Jue Li
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0062716
Abstract: In the past few decades, embryonic stem cells (ESCs) were of great interest as a model system for studying early developmental processes and because of their potential therapeutic applications in regenerative medicine. However, the underlying mechanisms of ESC differentiation remain unclear, which limits our exploration of the therapeutic potential of stem cells. Fortunately, the increasing quantity and diversity of biological datasets can provide us with opportunities to explore the biological secrets. However, taking advantage of diverse biological information to facilitate the advancement of ESC research still remains a challenge. Here, we propose a scalable, efficient and flexible function prediction framework that integrates diverse biological information using a simple weighted strategy, for uncovering the genetic determinants of mouse ESC differentiation. The advantage of this approach is that it can make predictions based on dynamic information fusion, owing to the simple weighted strategy. With this approach, we identified 30 genes that had been reported to be associated with differentiation of stem cells, which we regard to be associated with differentiation or pluripotency in embryonic stem cells. We also predicted 70 genes as candidates for contributing to differentiation, which requires further confirmation. As a whole, our results showed that this strategy could be applied as a useful tool for ESC research.
Advancement of Common Localization of Solitary Pulmonary Nodules ?for Video-assisted Thracoscopic Surgery
Cheng SHEN, Pengfei LI, Jue LI, Guowei CHE
- , 2018, DOI: : 10.3779/j.issn.1009-3419.2018.08.09
Abstract: Recently, with the proliferation of high-resolution computed tomography (CT), the frequency of small pulmonary nodules appears higher and more precise than previously estimated, especially in CT screening in patients with high risk factors for lung cancer. Video-assisted thoracoscopic surgery (VATS) provides a new minimally invasive treatment for the diagnosis and treatment of small pulmonary nodules. The VATS results in less pain, shorter hospital stay, and reduced surgical complications, making it more widely available. How to accurately locate and mark lesions is important for video-assisted thoracoscopic surgery. This article reviews the various techniques used to locate pulmonary nodules in surgery in recent years and summarizes the advantages and disadvantages of them.?
Shengmai Suppressed Vascular Tension in Umbilical Arteries and Veins of Human and Sheep  [PDF]
Xiaohui Yin, Xiuxia Gu, Yun He, Di Zhu, Jie Chen, Jue Wu, Xueqin Feng, Jinhao Li, Caiping Mao, Zhice Xu
Pharmacology & Pharmacy (PP) , 2015, DOI: 10.4236/pp.2015.66030
Abstract: Objective—The umbilical cord is a critical pathway between mothers and fetuses, and regulations of umbilical vessel tension are important for fetal growth. Shengmai is an herbal medicine being used in treatments of cardiovascular diseases. However, effects of Shengmai on human blood vessels and related pharmacological mechanisms are unclear. Methods—This study investigated the effects of related mechanisms of Shengmai and its key compounds on human and sheep umbilical arteries and veins using organ bath systems. Key Findings—Shengmai significantly suppressed phenylephrine-stimulated vasoconstriction in umbilical arteries and veins. NG-Nitro-L-arginine Methyl Estercould not change the Shengmai-suppressed vasoconstriction in human and sheep umbilical vessels. Among four key compounds of Shengmai, Ginsenoside Re, Ginsenoside Rb1, Ginsenoside Rg1, and Schisandrin, only Ginsenoside Re showed the significant effect similar to Shengmai’s in the umbilical vessels. In Ca2+-free solution, Ginsenoside Re did not affect vasoconstriction. In addition, caffeine- or phenylephrine-stimulated vasoconstriction were not changed by Ginsenoside Re. Either charybdotoxin or glibenclamide could inhibit Ginsenoside Re-caused inhibition of the stimulated vasoconstriction in both human and sheep umbilical vessels, where 4-aminopyridine did not show the similar inhibitory effect. Conclusion—The results provide new information on Shengmai’s effects and underlying mechanisms in umbilical vessels. Importantly, the information gained offers interesting potential for developing new drugs acting on umbilical cords for fetal medicine.
The effect of latency on bone lengthening force and bone mineralization: an investigation using strain gauge mounted on internal distractor device
Sekou Singare, Dichen Li, Yaxiong Liu, Zhongying Wu, Jue Wang
BioMedical Engineering OnLine , 2006, DOI: 10.1186/1475-925x-5-18
Abstract: Distraction tensions were investigated at different latency period in 36 rabbits using internal unilateral distractor. Strain gauges were prepared and attached to the distractor to directly assess the level of distraction tension during mandible lengthening. The tensile force environment of the mandible of rabbit during distraction was evaluated through in vivo experiments using two gauges.The animals were divided into 3 groups each containing 12 rabbits. Latency periods of 0, 4 and 7 days respectively were observed prior to beginning distraction. The distraction protocol consisted of a lengthening rate of 1 mm once daily for 8 days, followed by a consolidation phase of 2 weeks after which the animals were killed. Biopsies specimens were taken from the distracted area at the end of the distraction period. A non-distracted area of the mandible bone served as control. The specimens were analyzed by scanning electron microscopy to assess the ultrastructural pattern, and the bone mineralization.The resting tension acting on the distraction gap increases through distraction. The 7-day latency groups exhibit higher tension then those of 0-day and 4-days latency groups. Quantitative energy dispersive spectral analysis confirmed that immediate distractions were associated with lower calcium and phosphate atomic weight ratio.the latency periods could affect the bone lengthening tension and the bone mineralization process.Distraction osteogenesis is a surgical process for reconstruction of skeletal deformities. It involves gradual, controlled displacement of surgically created fractures, which results in simultaneous expansion of soft tissue and bone volume. It was first used in limb lengthening by Codivilla [1] in 1905, and later the use of this technique in canine mandible was first reported by Snyder et al [2]. In 1992 McCarthy et al. [3] demonstrated the clinical application of distraction osteogenesis technique in craniofacial skeleton for 4 young patients. To day, distr
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