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Search Results: 1 - 10 of 208494 matches for " Judeh L. Lama "
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Glucose-6-phosphate dehydrogenase regulation in the hepatopancreas of the anoxia-tolerant marine mollusc, Littorina littorea
Judeh L. Lama,Ryan A.V. Bell,Kenneth B. Storey
PeerJ , 2013, DOI: 10.7717/peerj.21
Abstract: Glucose-6-phosphate dehydrogenase (G6PDH) gates flux through the pentose phosphate pathway and is key to cellular antioxidant defense due to its role in producing NADPH. Good antioxidant defenses are crucial for anoxia-tolerant organisms that experience wide variations in oxygen availability. The marine mollusc, Littorina littorea, is an intertidal snail that experiences daily bouts of anoxia/hypoxia with the tide cycle and shows multiple metabolic and enzymatic adaptations that support anaerobiosis. This study investigated the kinetic, physical and regulatory properties of G6PDH from hepatopancreas of L. littorea to determine if the enzyme is differentially regulated in response to anoxia, thereby providing altered pentose phosphate pathway functionality under oxygen stress conditions. Several kinetic properties of G6PDH differed significantly between aerobic and 24 h anoxic conditions; compared with the aerobic state, anoxic G6PDH (assayed at pH 8) showed a 38% decrease in Km G6P and enhanced inhibition by urea, whereas in pH 6 assays Km NADP and maximal activity changed significantly between the two states. The mechanism underlying anoxia-responsive changes in enzyme properties proved to be a change in the phosphorylation state of G6PDH. This was documented with immunoblotting using an anti-phosphoserine antibody, in vitro incubations that stimulated endogenous protein kinases versus protein phosphatases and significantly changed Km G6P, and phosphorylation of the enzyme with 32P-ATP. All these data indicated that the aerobic and anoxic forms of G6PDH were the high and low phosphate forms, respectively, and that phosphorylation state was modulated in response to selected endogenous protein kinases (PKA or PKG) and protein phosphatases (PP1 or PP2C). Anoxia-induced changes in the phosphorylation state of G6PDH may facilitate sustained or increased production of NADPH to enhance antioxidant defense during long term anaerobiosis and/or during the transition back to aerobic conditions when the reintroduction of oxygen causes a rapid increase in oxidative stress.
Role Ambiguity and Role Conflict as Mediators of the Relationship between Orientation and Organizational Commitment
Mahfuz Judeh
International Business Research , 2011, DOI: 10.5539/ibr.v4n3p171
Abstract: The aim of this study was to examine the relationship between employee socialization and organization commitment. The study also aimed at assessing the mediating effect of role ambiguity and role conflict on the relationship between employee socialization and organization commitment in a large telecommunication organization located in Jordan. A survey was administered to 300 employees, and 256 questionnaires were returned and usable for statistical analysis. Descriptive statistics, correlations and regression analyses were used to test the hypotheses. Findings reported that both proposed mediators, role ambiguity and role conflict, emerged as significant mediators of the relationship between employee socialization and organization commitment. Based on the findings and limitations of the study, further research was needed to examine the correlation of socialization, job stressors, and organizational commitment on other work environments.
Selected Personality Traits and Intent to Leave: A Field Study in Insurance Corporations
Mahfuz Judeh
International Business Research , 2012, DOI: 10.5539/ibr.v5n5p88
Abstract: This study attempted to examine the effect of two selected personality traits on intent to leave. A theoretical framework was proposed to suggest link among the two variables and a questionnaire was distributed to collect data from employees in insurance corporations in Jordan. Of the 500 questionnaires distributed, 331 valid responses were received, resulting in a 66.2% response rate. The results revealed that both conscientiousness and extraversion were negatively related to intent to leave. As for the results of the demographic factors, the study showed that there were significant differences in intent to leave based on gender and age, while there were no significant differences due to marital status. Finally, this study suggested that management should adopt appropriate strategies and enhance human resource practices that lead to positive personality traits which lead to increased retention of employees.
An Examination of the Effect of Employee Involvement on Teamwork Effectiveness: An Empirical Study
Mahfuz Judeh
International Journal of Business and Management , 2011, DOI: 10.5539/ijbm.v6n9p202
Abstract: The aim of this study was to determine the level of employee involvement and extent of teamwork effectiveness among employees working in the Jordanian glass and ceramic industries listed in Amman Stock Exchange in Jordan. The study aimed also at examining the significant effect of employee empowerment on teamwork effectiveness. Furthermore, the study investigated the significant differences that may exist in employee involvement due to differences in age, marital status, and educational level. Data were collected from 176 participants and then analyzed using descriptive statistics, one sample t-test and independent sample t-test, linear regression, and ANOVA. Findings indicated that both employee involvement and teamwork effectiveness were at a high to moderately high level score. Furthermore, the findings of the study revealed a significant effect of employee involvement on teamwork effectiveness. At the same time results indicated that there were no significant differences towards employee involvement due to gender or marital status, while participants significantly differed in terms of educational level. The results of this study had many implications for human resources and other practitioners and managers who must enhance the teamwork atmosphere in their organizations. As for the originality/value, employee involvement and teamwork effectiveness had previously lacked attention, especially in the Middle East countries, and this paper contributed to the body of knowledge by empirically studying the correlation between employee involvement and teamwork effectiveness.
An Analysis of the Relationship between Trust and Employee Empowerment: A Field Study
Mahfuz A. Judeh
International Business Management , 2012, DOI: 10.3923/ibm.2012.264.269
Abstract: Trust within organization plays an important role in enhancing the interaction among superiors and subordinates which are reflected on the way effective organizational goals are achieved. One of the core functions of effective manager is to enhance confidence climate with his/her relations with peers and subordinates. Furthermore, employee empowerment has become an important management approach to motivate subordinates and lead them in an efficient manner. Employee empowerment involves delegation of authority through which lower level management can make autonomous decisions without referring to their superiors. Data were collected from a sample of 206 participants whose responses were usable for statistical analysis. Descriptive analysis, one sample t-test and linear regression are performed to reach the final results. Results of the study indicate that trust is at a medium degree while employee empowerment is at a high level. At the same time, results show that there is a significant correlation between within organization trust and employee empowerment. It is hoped that this study will offer some insight for the importance of within organization trust to all management approaches and techniques, especially in effective employee empowerment. The study proposes several directions for further research such as conducting more empirical studies on the antecedents and outcomes of both within organization trust and employee empowerment.
Molecular identification of species of the Genus Euglossa Latreille (Hymenoptera: Apidae, Euglossini)
López-Uribe, Margarita M.;Del Lama, Marco A.;
Neotropical Entomology , 2007, DOI: 10.1590/S1519-566X2007000500012
Abstract: euglossine bees interact with more than 60 plant families of the neotropical region. the richness and abundance of these bees have been intensively studied in different ecosystems using the methodology of capturing males with chemical baits. females are poorly known for most of the species and morphological characters for their taxonomic classification have not yet been described. the purpose of this study was to use allozymes and restriction patterns of the mitochondrial regions 16s and cyt b to identify species of euglossa latreille. bees were collected while visiting thevetia peruviana (apocynaceae) flowers in five cities of the state of s?o paulo, brazil. three euglossa species were identified among the 305 individuals collected. euglossa cordata (l.) was the only species found in all cities, while e. securigera dressler and e. townsendi cockerell were restricted to two and one cities respectively. est-3 was a diagnostic marker, whereas icd, mdh, me and pgm were informative for species identification when used in combination. restriction by vspi of the amplified 16s fragment differentiated the three species and showed intraspecific polymorphism for e. cordata and e. securigera. the cyt b region showed distinctive patterns for e. townsendi but it was not possible to differentiate the other two species. our results describe potentially useful genetic markers for the identification of euglossa spp. at the species and group level.
Pattern Of Skin Diseases In A Rural Village Development Community Of Nepal
R Shrestha,DP Shrestha,L Lama,D Gurung,I Rosdahl
Nepal Journal of Dermatology, Venereology & Leprology , 2014, DOI: 10.3126/njdvl.v12i1.10595
Abstract: 72 Introduction: Skin diseases are a common cause of morbidity in Nepal as per the health services report. There is limited information on the prevalence and pattern of skin diseases in the community. The objective of this study was to determine the pattern of skin diseases in a rural village development community of Nepal. Materials and methods:? Two? dermatologic? health camps were conducted, during which, the villagers were examined by dermatologists. The skin diseases diagnosed were recorded in a proforma. Results: There were 433 individuals examined and 359 (male-47.9%; female-52.1%) had skin disease identified clinically (camp prevalence- 83%). The age of patients ranged from 1 to 80 years (mean-24.5; SD±15.9), with majority in the age group of 10-19 years. The most common skin disease category was eczemas (36.4%), followed by infections (28.4%), acne (22%), pigment disorders (34%) and urticaria (12.3%). Conclusion: Skin diseases were common in the community. The five most common Skin disease categories were eczemas, infections, acne and pigment disorders were the more common conditions. DOI: http://dx.doi.org/10.3126/njdvl.v12i1.10595 Nepal Journal of Dermatology, Venereology & Leprology Vol.12(1) 2014 pp.41-44 ?
Mala colocación de los electrodos: causa de elevación del ST
Alexis Lama
Revista Chilena de Cardiología , 2009,
Estatinas en Prevención Primaria?
Alexis Lama
Revista Chilena de Cardiología , 2010,
Los conflictos de intereses y el cardiólogo
A Lama
Revista Chilena de Cardiología , 2010,
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