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Search Results: 1 - 10 of 84008 matches for " José Manuel Rivera Otero "
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Qué valoran los electores persuadibles en la decisión de votar?
Patricio Soares Costa,José Manuel Rivera Otero
Revista de Investigaciones Políticas y Sociológicas (RIPS) , 2012,
Abstract: Este artículo explora los principales determinantes en la decisión de voto de los electores que no votan siempre al mismo partido en las diferentes elecciones legislativas portuguesas. Para este propósito se construyeron dos modelos (PS y PSD) basados en las contribuciones de la Ciencia Política y de la Psicología Social, y más concretamente en la Theory of Planned Behavior (TpB). Es importante se alar el poder explicativo de los modelos obtenidos que, en el caso del PS supera el 80% y en el caso del PSD el 70%. Los predictores directos de la intención de voto son la proximidad partidaria y las dimensiones de la TpB, ora para el PS ora para el PSD. Factores como el soporte afectivo hacia el líder, la satisfacción y la confianza en el trabajo desarrollado por el gobierno, también se mostraron relevantes en la toma de decisión de este segmento.
The New Components of Catalan Nationalism  [PDF]
Erika Jaráiz, ángel Cazorla, José Manuel Rivera
Open Journal of Political Science (OJPS) , 2019, DOI: 10.4236/ojps.2019.91009
Abstract: In this paper we identify four fundamental factors in the construction of the nation-preconditions, political opportunity structure, mobilization and speech-, integrated by a series of elements that serve as indicators for the approach to our explanatory model. With our analysis we demonstrate that in Catalonia nationalism is explained by contextual elements, elements of mobilisation, fundamentally the leadership, and by the “process” itself. These findings allow us to talk about a Catalan nationalism constructed on the bases of reasons that have to do with unjust treatment by Spanish governments, trust and expectations.
Increased Expression of Fatty-Acid and Calcium Metabolism Genes in Failing Human Heart
Vanessa García-Rúa, Manuel Francisco Otero, Pamela Virginia Lear, Diego Rodríguez-Penas, Sandra Feijóo-Bandín, Teresa Noguera-Moreno, Manuel Calaza, María álvarez-Barredo, Ana Mosquera-Leal, John Parrington, Josep Brugada, Manuel Portolés, Miguel Rivera, José Ramón González-Juanatey, Francisca Lago
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0037505
Abstract: Background Heart failure (HF) involves alterations in metabolism, but little is known about cardiomyopathy-(CM)-specific or diabetes-independent alterations in gene expression of proteins involved in fatty-acid (FA) uptake and oxidation or in calcium-(Ca2+)-handling in the human heart. Methods RT-qPCR was used to quantify mRNA expression and immunoblotting to confirm protein expression in left-ventricular myocardium from patients with HF (n = 36) without diabetes mellitus of ischaemic (ICM, n = 16) or dilated (DCM, n = 20) cardiomyopathy aetiology, and non-diseased donors (CTL, n = 6). Results Significant increases in mRNA of genes regulating FA uptake (CD36) and intracellular transport (Heart-FA-Binding Protein (HFABP)) were observed in HF patients vs CTL. Significance was maintained in DCM and confirmed at protein level, but not in ICM. mRNA was higher in DCM than ICM for peroxisome-proliferator-activated-recept?or-alpha(PPARA), PPAR-gamma coactivator-1-alpha (PGC1A) and CD36, and confirmed at the protein level for PPARA and CD36. Transcript and protein expression of Ca2+-handling genes (Two-Pore-Channel 1 (TPCN1), Two-Pore-Channel 2 (TPCN2), and Inositol 1,4,5-triphosphate Receptor type-1 (IP3R1)) increased in HF patients relative to CTL. Increases remained significant for TPCN2 in all groups but for TPCN1 only in DCM. There were correlations between FA metabolism and Ca2+-handling genes expression. In ICM there were six correlations, all distinct from those found in CTL. In DCM there were also six (all also different from those found in CTL): three were common to and three distinct from ICM. Conclusion DCM-specific increases were found in expression of several genes that regulate FA metabolism, which might help in the design of aetiology-specific metabolic therapies in HF. Ca2+-handling genes TPCN1 and TPCN2 also showed increased expression in HF, while HF- and CM-specific positive correlations were found among several FA and Ca2+-handling genes.
Differential Gene Expression of Cardiac Ion Channels in Human Dilated Cardiomyopathy
Maria Micaela Molina-Navarro, Esther Roselló-Lletí, Ana Ortega, Estefanía Tarazón, Manuel Otero, Luis Martínez-Dolz, Francisca Lago, José Ramón González-Juanatey, Francisco Espa?a, Pablo García-Pavía, José Anastasio Montero, Manuel Portolés, Miguel Rivera
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0079792
Abstract: Background Dilated cardiomyopathy (DCM) is characterized by idiopathic dilation and systolic contractile dysfunction of the cardiac chambers. The present work aimed to study the alterations in gene expression of ion channels involved in cardiomyocyte function. Methods and Results Microarray profiling using the Affymetrix Human Gene? 1.0 ST array was performed using 17 RNA samples, 12 from DCM patients undergoing cardiac transplantation and 5 control donors (CNT). The analysis focused on 7 cardiac ion channel genes, since this category has not been previously studied in human DCM. SCN2B was upregulated, while KCNJ5, KCNJ8, CLIC2, CLCN3, CACNB2, and CACNA1C were downregulated. The RT-qPCR (21 DCM and 8 CNT samples) validated the gene expression of SCN2B (p < 0.0001), KCNJ5 (p < 0.05), KCNJ8 (p < 0.05), CLIC2 (p < 0.05), and CACNB2 (p < 0.05). Furthermore, we performed an IPA analysis and we found a functional relationship between the different ion channels studied in this work. Conclusion This study shows a differential expression of ion channel genes involved in cardiac contraction in DCM that might partly underlie the changes in left ventricular function observed in these patients. These results could be the basis for new genetic therapeutic approaches.
Neural Network Approach to Modelling the Behaviour of Ionic Polymer-Metal Composites in Dry Environments  [PDF]
Andrés Díaz Lantada, Pilar Lafont Morgado, José Luis Mu?oz Sanz, Juan Manuel Mu?oz Guijosa, Javier Echávarri Otero
Journal of Signal and Information Processing (JSIP) , 2012, DOI: 10.4236/jsip.2012.32018
Abstract: Ionic polymer-metal composites (IPMCs) are especially interesting electroactive polymers because they show large a deformation in the presence of a very low driving voltage (around 1 - 2 V) and several applications have recently been proposed. Normally a humid environment is required for the best operation, although some IPMCs can operate in a dry environment, after proper encapsulation or if a solid electrolyte is used in the manufacturing process. However, such solutions usually lead to increasing mechanical stiffness and to a reduction of actuation capabilities. In this study we focus on the behaviour of non-encapsulated IPMCs as actuators in dry environments, in order to obtain relevant information for design tasks linked to the development of active devices based on this kind of smart material. The non-linear response obtained in the characterisation tests is especially well-suited to modelling these actuators with the help of artificial neural networks (ANNs). Once trained with the help of characterisation data, such neural networks prove to be a precise simulation tool for describing IPMC response in dry environments.
Heats of Mixing Using an Isothermal Titration Calorimeter: Associated Thermal Effects
Manuel Rodríguez de Rivera,Fabiola Socorro,José S. Matos
International Journal of Molecular Sciences , 2009, DOI: 10.3390/ijms10072911
Abstract: The correct determination of the energy generated or absorbed in the sample cell of an Isothermal Titration Calorimeter (ITC) requires a thorough analysis of the calorimetric signal. This means the identification and quantification of any thermal effect inherent to the working method. In this work, it is carried out a review on several thermal effects, studied by us in previous work, and which appear when an ITC is used for measuring the heats of mixing of liquids in a continuous mode. These effects are due to: (i) the difference between the temperature of the injected liquid and the temperature of the mixture during the mixing process, (ii) the increase of the liquid volume located in the mixing cell and (iii) the stirring velocity. Besides, methods for the identification and quantification of the mentioned effects are suggested.
Propiedades psicométricas de una escala para medir apoyo social percibido en pacientes chilenos con diabetes tipo 2
ORTIZ PARADA,MANUEL; BAEZA RIVERA,MARíA JOSé;
Universitas Psychologica , 2011,
Abstract: the present study tested the psychometric properties of the zimet et al.' multidimensional scale of perceived social support (mspss), in patients with type 2 diabetes mellitus (dm) (n = 76) from temuco city, chile. the total scale shown appropriate levels of internal consistency (0,849). an exploratory factorial analysis, with varimax rotation, was performed over the mspss measures. in agreement with the original scale, three factors were obtained explaining 66,8% of the variance. these results suggest that mspss is a psychometrically sound instrument that can be applied to patients with type 2 diabetes.
Psychometric Properties of a Scale Designed to Measure Perceived Social Support in Chilean Patients with Type 2 Diabetes
Manuel Salvador Ortiz Parada,María José Baeza Rivera
Universitas Psychologica , 2011,
Abstract: The present study tested the psychometric properties of the Zimet et al.’ Multidimensional Scale of Perceived Social Support (MSPSS), in patients with Type 2 Diabetes Mellitus (DM) (n = 76) from Temuco City, Chile. The total scale shown appropriate levels of internal consistency (0,849). An exploratory factorial analysis, with Varimax rotation, was performed over the MSPSS measures. In agreement with the original Scale, three factors were obtained explaining 66,8% of the variance. These results suggest that MSPSS is a psychometrically sound instrument that can be applied to patients with Type 2 Diabetes.
Influence of Rainfall Pattern in the Seasonal Variation of Fish Abundance in a Tropical Estuary with Restricted Marine Communication  [PDF]
Manuel Castillo-Rivera
Journal of Water Resource and Protection (JWARP) , 2013, DOI: 10.4236/jwarp.2013.53A032
Abstract:
Pueblo Viejo Lagoon is an estuary with restricted communication with the sea, so the freshwater influence tends to be more important. Therefore, the study focused on testing the hypothesis that the seasonal changes in species abundance would be mainly related to the local rainfall pattern. Monthly samplings were carried out over a one-year, using a seine net. A total of 9108 individuals were caught, corresponding to 66 species of fish, most of them with marine origin. Canonical correspondence analysis revealed that the rainfall-salinity gradient was revealed to be the most important driving force in the seasonal variation of fish composition. In this way, it was observed that seasonal fluctuations in total fish number were linked to preceding fluctuations (one month) in local rainfall. Similar pattern was exhibited by the abundance of Anchoa mitchilli (the most abundant species), Oreochromis mossambicus and Ariopsis felis, and this delayed effect was significant (cross-correlation analyses). In addition, the rainfall showed a direct influence (significant positive correlations) on abundance of D. auratus and M. martinica. The association between fish number and the rainfall regime seems to be related to lagoon productivity and the trophic responses of these species. By contrast, Brevoortia gunteri and Menidia beryllina showed an inverse correlation with rainfall. Other environmental variables (also influenced by rainfall regime) showed a significant relationship with A. hepsetus (salinity), B. chrysoura (depth) and M. curema (turbidity). Thus, at least 12 species showed some relationship with local rainfall, which accounted for 81.27% of the total number of fish collected. Although it is difficult to separate the relative importance of
Obstrucción ureteral parcial crónica por vena ovárica: Descripción de un caso y revisión de la literatura
Maldonado-Alcaraz, Efraín;Otero-García, José Manuel;
Gaceta médica de México , 2005,
Abstract: we present a female patient with chronic loin pain caused by partial obstruction of the urether secondary to ovarian vein crossing. we highlight the benefit derived from surgical treatment.
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