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Search Results: 1 - 10 of 385311 matches for " José Jesús; Morales Vallarta "
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Evaluación del efecto protector de 2 inmunógenos de Trichinella. spiralis en ratas Long Evans con modificación nutricional e infectado con Trichinella spiralis
Maldonado Tapia,Claudia; Reveles Hernández,Rosa Gabriela; Saldivar Elías,Sergio; Mu?oz Escobedo,José Jesús; Morales Vallarta,Mario; Moreno García,María Alejandra;
Archivos Venezolanos de Farmacología y Terapéutica , 2007,
Abstract: the trichinellosis is an endemic zoonotics, cosmopolitan, which is hosted in rats, pigs, and other mammals including humans. the presence of trichinellosis is due to ingestion of insufficiently cooked swine meat. poor countries with low medical resources are mainly affected by the disease. a numbered of immunogen have been characterized 45kda was found to be the immunodominant most effective against t. spiralis, unfortunately a vaccine has not yet been found. malnutrition (dn) effects have been described/detected in lymphatic organs. the immune mechanisms of the host have been altered with dn caloric-proteic (dpc). objetive: the protective effect of two 2 immunogen of t. spiralis was evaluated in long evans rats with nutritional modifications and infected with t. spiralis. methods: eighty long evans rats (30 days old) were divided into two groups a 40 nut with 24% protein and a 40 dn with 12% protein of which eight groups were divided again into the different treatments: a) 10 control rats, b) 10 t. spiralis infected rats, c)10 immunized rats with total soluble antigens (ast), d) 10 immunized with 45 kda of t. spiralis immunogen (one application per week in four dosages), challenged after the first week of immunization, sacrificed after the sixth week of post-infection. evaluation parameters: parasite charge determination using artificial digestion, (d/a), morphological characteristics of the nurse cell were determined by the tissue compression tests. detention to immune response was determined by wb. results: different treatments to treat the nut, dn, immunized and infected rats were obtained by d/a. a significant difference was shown in the ll quantities present in 30 g of muscle. the nut and dn rats control, in ll absence, and in the groups of nut rats, 200 ul of ll were collected, in the dn infected group 400ul of ll were collected, in the nut immunized with ast and infected, 10 ul of ll were collected. meanwhile the rats treated with dn recovered 100 ul of ll.
Efecto del estado nutricional en la susceptibilidad o resistencia a la infección de Trichinella spiralis en modelo murino
M. en C. Claudia Maldonado Tapia,Mario Morales Vallarta,M. en C. José Jesús Mu?oz Escobedo,M.V.Z. Sergio Saldivar Elías
REDVET , 2007,
Abstract: Resumen La Trichinellosis es una zoonosis causada inadecuadas. por nematodos del género Trichinella se trasmite principalmente por alimentos Objetivo: evaluar el efecto del estado contaminados con larvas infectantes (LI) de nutricional en la susceptibilidad a la T. spiralis. Además de ser ampliamente infección de Trichinella spiralis en modelo difundida se adapta a los distintos climas y murino. regiones del mundo, y es una parasitosis que afecta a la mayoría de los mamíferos. El Metodología: consistió en 2 grupos; adecuado estado nutricional permite a los Nutridos con una dieta de 24 % (Nut) y individuos una respuesta inmune ante la Desnutridos con una dieta del 12 % de presencia de patógenos externos. De igual proteína. (DN) y posteriormente se modo se menciona que todo ser vivo nutrido infectaron con diferentes cargas parasitarias tiene una calidad de vida conveniente. La 500 LI (Larvas Infectantes de T.spiralis) desnutrición en ni os es un problema que se
Evaluacion del albendazol, ivermectina y nitazoxanida en infeccion causada por trichinella spiralis en modelo suino
Chávez Ruvalcaba,María Isabel; Reveles Hernández,Rosa Gabriela; Saldivar Elias,Sergio J; Mu?oz Escobedo,José Jesús; Morales Vallarta,Marío R; Moreno García,María Alejandra;
Archivos Venezolanos de Farmacología y Terapéutica , 2006,
Abstract: trichinellosis is a zoonotic parasitary disease which is accidentally transmitted to men by ingestion of meat products not well cooked, of infected animals. in mexico the pig is the main source of contamination the applied treatment has been unspecific. the effective treatment for this disease is not truly known. this study is led to know if albendazole (abz), nitazoxanide (nzx) and ivermectin (ivm) are effective in the treatment of intestinal phase (ip) and muscular phase (mp) of trichinellosis. therefore we consider convenient to know what medicament is more effective against the t. spiralis parasite in both phases. 18 york pigs were used, 10 groups were made: 1- healthy control in ip 2- infected control in ip, 3 - infected treated with abz in ip, 4 - infected and treated with ivm in ip, 5 - infected and treated with nzx in ip, 6.-healthy control in mp, 7.- infected control in mp, 8- infected and treated with abz in muscular phase (mp), 9 - infected and treated with ivm in mp, 10 - infected and treated with nzx in mp. the statistic analysis was an experimental design completely by random and a factorial treatment design. concluding that the abz besides being but effective in fi in fm it presents an effectiveness of 100% against the infection.
Detección de los cambios Fenotípicos en productos de Ratas Long Evans infectadas con Trichinella spiralis y tratadas con Albendazol
Chávez Guajardo,Elsa Gabriela; Morales Vallarta,Mario R; Saldivar Elías,Sergio J; Reveles Hernández,R. Gabriela; Mu?oz E,José Jesús; Moreno García,María Alejandra;
Archivos Venezolanos de Farmacología y Terapéutica , 2010,
Abstract: trichinella spiralis is one of the causative agents of the trichinellosis, is a zoonosis of world-wide distribution, affects to big number of mammals like this as to the human. in mexico the main cause of infection associate with the consumption of pig infected meat with t. spiralis. in this work detected the phenotypical changes in long evans rats products infected with trichinells spiralis and threated with albendazol medication. use rats cepa long evans ina reproductive age. divided in groups, included controls and with treatment varying of one to fourteen days of treatment, to synchronize the management in the rats realized vaginal.smears for the detection of the parasites used direct techniques of understanding in plate and artificial digestion and the indirect technician of miid, for the phenotypical changes of baby rats obtained realized a detailed analysis with stereoscopic microscope.
Efecto del Albendazol en ratas Long Evans gestantes e infectadas con T. spiralis
Chávez Guajardo,Elsa Gabriela; Morales Vallarta,Mario R; Saldivar Elías,Sergio J; Reveles Hernández,R. Gabriela; Mu?oz E,José Jesús; Moreno García,María Alejandra;
Archivos Venezolanos de Farmacología y Terapéutica , 2010,
Abstract: the albendazol is the antihelmintic of first election for several parasitism, among them trichinellosis, nevertheless, the time of treatment must be per prolonged periods. the aim of this work was to determine the effect of this medicine on long rats evans pregnant and infected with t. spiralis. we synchronize the rats to develop them and to infect them, the treatment went of one to fourteen days, used the hematoxilina-eosin technique to verify the effect on the liver and the reproductive apparatus and verified the number of young for each treatment and if correspondence between the obtained characteristics of the reproductive apparatus and young existed, the results indicate a degeneration of weaves as increases the time of treatment in addition is observed that i number of young is directly affected when increasing the treatment.
Detección de da?o estructural por algoritmos genéticos: una comparación de diferentes tipos de codificación de individuos
Villalba Morales,Jesús Daniel; Laier,José Elías;
Ingeniería y Desarrollo , 2010,
Abstract: en este artículo se aplican los algoritmos genéticos para resolver el problema de detección de da?o estructural, y se comparan tres tipos de codificación de individuos: binaria, real y binaria con código redundante. los algoritmos de código binario y real calculan la extensión del da?o para cada elemento en la estructura, por lo tanto, para mejorar su desempe?o fue utilizado un proceso de re-inicialización de individuos. por su parte, el algoritmo de código redundante busca en forma dinámica cuáles son los elementos da?ados y cuantifica el da?o solo para esos elementos. para determinar el desempe?o de los algoritmos se analiza una armadura sobre diversos escenarios de da?o simple y múltiple, y el da?o es considerado como una reducción en el módulo de elasticidad de los elementos da?ados. los resultados muestran que el algoritmo que mejor localiza y cuantifica el da?o corresponde al algoritmo genético de código redundante.
Detección de da o estructural por algoritmos genéticos: una comparación de diferentes tipos de codificación de individuos
Jesús Daniel Villalba Morales,José Elías Laier
Ingeniería y Desarrollo , 2010,
Abstract: En este artículo se aplican los algoritmos genéticos para resolver el problema de detección de da o estructural, y se comparan tres tipos de codificación de individuos: binaria, real y binaria con código redundante. Los algoritmos de código binario y real calculan la extensión del da o para cada elemento en la estructura, por lo tanto, para mejorar su desempe o fue utilizado un proceso de re-inicialización de individuos. Por su parte, el algoritmo de código redundante busca en forma dinámica cuáles son los elementos da ados y cuantifica el da o solo para esos elementos. Para determinar el desempe o de los algoritmos se analiza una armadura sobre diversos escenarios de da o simple y múltiple, y el da o es considerado como una reducción en el módulo de elasticidad de los elementos da ados. Los resultados muestran que el algoritmo que mejor localiza y cuantifica el da o corresponde al algoritmo genético de código redundante
MIDAS: Software for the detection and analysis of lunar impact flashes
José M. Madiedo,José L. Ortiz,Nicolás Morales,Jesús Cabrera-Ca?o
Physics , 2015, DOI: 10.1016/j.pss.2015.03.018
Abstract: Since 2009 we are running a project to identify flashes produced by the impact of meteoroids on the surface of the Moon. For this purpose we are employing small telescopes and high-sensitivity CCD video cameras. To automatically identify these events a software package called MIDAS was developed and tested. This package can also perform the photometric analysis of these flashes and estimate the value of the luminous efficiency. Besides, we have implemented in MIDAS a new method to establish which is the likely source of the meteoroids (known meteoroid stream or sporadic background). The main features of this computer program are analyzed here, and some examples of lunar impact events are presented.
Participación de los canales de calcio dependientes de voltaje en el desarrollo de la epilepsia Participation of voltage-dependent calcium channels in the development of epilepsy
Jesús Servando Medel Matus,Fernando Rafael Ramos Morales,José Correa Basurto,Jesús Samuel Cruz Sánchez
Acta bioqu?-mica cl?-nica latinoamericana , 2010,
Abstract: La epilepsia es una afección crónica producida por diferentes etiologías, caracterizada por la repetición de crisis debidas a una descarga excesiva de las neuronas cerebrales asociadas a síntomas clínicos o paraclínicos. Se debe a una despolarización rápida, en la membrana, de iones en una población de neuronas susceptibles, es decir, un cambio repentino en la carga intracelular negativa a positiva. Las causas más conocidas son: alteraciones genéticas, anoxia perinatal, traumatismos, tumores, malformaciones congénitas, alteraciones metabólicas, intoxicaciones farmacológicas, infecciones del sistema nervioso. Una crisis epiléptica es la aparición transitoria de signos y síntomas anormales causados por la actividad neuronal excesiva, mientras que la epilepsia se caracteriza por una permanente predisposición a generar crisis. En la despolarización de la membrana neuronal, los iones calcio desempe an un papel importante debido a que son mensajeros intracelulares que regulan funciones como: liberación de neurotransmisores, neurosecreción, excitación neuronal, supervivencia de neuronas y regulación de expresión de genes. El ingreso de calcio a través de la membrana plasmática representa una forma para controlar el nivel intracelular de calcio. Se conoce poco sobre el mecanismo de entrada del calcio a la neurona pero un progreso notable representa la comprensión de la estructura, función y regulación de los canales de calcio dependientes de voltaje. Epilepsy is defined as a chronic condition produced by different etiologies, characterized by the repetition of crises due to an excessive discharge of the cerebral neurons assoclated wlth cllnlcal symptoms. It responds to a fast ion depolarization in a population of abnormal neurons. Causes of epilepsy are: genetíc alteratíons, perínatal anoxía, traumatísms, tumors, congenital malformations, metabolic alterations, drug poisonings, and infections of the nervous system. Epileptic selzure Is the transitory occurrence of signs and abnormal symptoms caused by excessive or synchronous neurona! activity whereas, epilepsy Is characterized by a permaneni predisposition to genérate seizures. During depolarization of neurona! membrane, calcium ions play an important role because they are intracellular messengers that regúlate functions llke: neurotransmltter reléase, neurosecretlon, neuronal excltatlon, neuron survlval and gene expresslon regulatlon . The Influx of calcium through the plasmatlc membrane represents a way to control Intracellular calcium level. The mechanlsm of the entrance of calcium to the neuron Is llttle k
Factores asociados a mortalidad por fungemias causadas por Candida sp. en ni?os
Reséndiz-Sánchez, Jesús;Morales-Aguirre, José Juan;
Boletín médico del Hospital Infantil de México , 2007,
Abstract: introduction. a dramatic increase in the incidence of fungal infections has been reported in recent years. this is especially true with regards to infections due to candida non albicans. the main risk factors associated with mortality include: age, invasive procedures and previous use of antibiotics. material and methods. a retrospective study of series of cases, in the hospital infantil de mexico federico gomez, including children less than 18 years of age, with a diagnosis of systemic fungal infection and the isolation of c. albicans from sterile sites, during the period from may 1999 to december 2004. the objective was to analyze the factors associated to death. we reviewed the microbiology archives to identify the isolation of yeast from sterile sites including: blood, urine, csf, and biopsy specimens. the information was obtained from the hospital mycology laboratory. the individual patient record was carefully reviewed in efforts to determine possible risk factors at the time of the positive cultures as well as the antecedent 30 days. results. we observed an increase in the rates of infection per 1 000 discharges from 1999 to 2004. we observed 45 infectious events due to candida sp., with a mortality of 35.5%. we did not identify the species in 18 patients, c. albicans in 16 events and other non albicans in 24%. in 12 patients the underlying diagnosis was cancer; gastrointestinal malformations in 6, congenital heart disease in 12 patients, malformations of digestive tube and sepsis in 6, congenital cardiopathy and renal failure in 3, hepatic diseases in 4 and others disease entities in 10 patients. in 88.8% the infections were of nosocomial origin. the age group with the highest mortality was newborns. the main factors associated with mortality were: the antecedent of thrombocytopenia and neutropenia, as well as being intubated at the moment of the infection. conclusions. fungal infections and particularly those due to candida sp., represent an important cause
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