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Search Results: 1 - 10 of 22936 matches for " Jorge; Niederbacher "
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Correlation between the Childhood-Asthma Control Test and the Criterion for Clinical Asthma Control  [PDF]
Carlos José Ortiz-Lizcano, Jürg Niederbacher-Velásquez, Luis Alfonso Díaz-Martínez
Health (Health) , 2016, DOI: 10.4236/health.2016.87065
Abstract: Setting: Three pediatric pneumatologist offices in Bucaramanga, Colombia. Objective: To establish the concordance between medical criteria and the Childhood-Asthma Control Test (cACT). Design: Study of the assessment of diagnostic technology using transverse sampling. 127 asthma patients aged between 4 and 11 years and their parents filled before clinical evaluation made by a pediatric pneumologist. Patients were classified as controlled or not controlled. Criteria validity was established comparing this classification using Cohen’s kappa and performance indicators according to ROC analysis. Results: 78% of the patients were controlled; patients who are not controlled have a higher score in cACT (mean difference: 3.25 points). Concordance among cACT subscales is acceptable (ρ = 0.554). cACT’s sensitivity was 53.6%, specificity 78.8%, positive likelihood ratio (LR+) 2.53, and negative likelihood ratio (LR-) 0.59. The best cut-off point is 15, with 98% sensitivity, a specificity of 14.3%, LR+ in 1.14, and LR- in 0.14. Conclusions: cACT is a valid tool to determine asthma control in children without replacing medical criteria or other clinical tests. In populations with difficult access to high complexity services, it is useful to decide whether urgent referral to the specialist is necessary.
Contaminación biológica intradomiciliaria y su relación con síntomas respiratorios indicativos de asma bronquial en preescolares de Bucaramanga, Colombia
Herrera,Astrid B; Rodríguez,Laura A; Niederbacher,Jürg;
Biomédica , 2011,
Abstract: introduction. indoorair pollution may play an important role in development and exacerbation of asthma in children. objective. the association between the presence of indoor biological contaminants and respiratory symptoms related to asthma was assessed in preschool children. materials and methods. this cross-sectional study was undertaken in bucaramanga, colombia, and included children <7 years of age living in two urban areas of with different levels of outdoor air pollution. the 678 children were an average of 3.5 years of age. respiratory symptoms indicative of asthma and indoor air pollutants were assessed by previously validated questionnaires.. biological samples potentially containing mites and fungi were collected by standardized laboratory methods. the log binomial regression model was used for multivariate analysis, using adjusted prevalence ratios (pr). results. the prevalence of asthmatic respiratory symptoms was 8.0%; (95% c.i: 5.6-9.6), without significant differences between the two areas. binomial model analysis showed that asthma symptoms were associated with mites (pr 1.78; 95% c.i. 1.0-3.0), acremonium sp (pr 6.24; 95 c.i.: 3.8-10.0) and a history of child pneumonia (pr 4.0; 95% c.i. 2.5-6.4), allergic rhinitis (pr 1.9; 95% c.i.: 1.2-3.1), prematurity (pr 3.4; 95% c.i. 1.8-6.5), parents with asthma (pr 2.6; 95% c.i. 1.4-5.0) and pet ownership (pr 0.4; 95% c.i. 0.2-0.9). conclusions. the indoor exposure to biological contaminants (dust mites and fungi), history of prematurity, pneumonia, rhinitis and family history of asthma increased the occurence of symptoms suggestive of asthma in young children.
Biological pollution and its relationship with respiratory symptoms indicative of asthma, Bucaramanga, Colombia Contaminación biológica intradomiciliaria y su relación con síntomas respiratorios indicativos de asma bronquial en preescolares de Bucaramanga, Colombia
Astrid Berena Herrera,Laura A. Rodríguez,Jürg Niederbacher
Biomédica , 2011,
Abstract: Introduction. Indoor air pollution may play an important role in development and exacerbation of asthma in children. Objective. The association between the presence of indoor biological contaminants and respiratory symptoms related to asthma was assessed in preschool children. Materials and methods. This cross-sectional study was undertaken in Bucaramanga, Colombia, and included children <7 years of age living in two urban areas of with different levels of outdoor air pollution. The 678 children were an average of 3.5 years of age. Respiratory symptoms indicative of asthma and indoor air pollutants were assessed by previously validated questionnaires.. Biological samples potentially containing mites and fungi were collected by standardized laboratory methods. The log binomial regression model was used for multivariate analysis, using adjusted prevalence ratios (PR). Results. The prevalence of asthmatic respiratory symptoms was 8.0%; (95% C.I: 5.6-9.6), without significant differences between the two areas. Binomial model analysis showed that asthma symptoms were associated with mites (PR 1.78; 95% C.I. 1.0-3.0), Acremonium sp (PR 6.24; 95 C.I.: 3.8-10.0) and a history of child pneumonia (PR 4.0; 95% C.I. 2.5-6.4), allergic rhinitis (PR 1.9; 95% C.I.: 1.2-3.1), prematurity (PR 3.4; 95% C.I. 1.8-6.5), parents with asthma (PR 2.6; 95% C.I. 1.4-5.0) and pet ownership (PR 0.4; 95% C.I. 0.2-0.9). Conclusions. The indoor exposure to biological contaminants (dust mites and fungi), history of prematurity, pneumonia, rhinitis and family history of asthma increased the occurence of symptoms suggestive of asthma in young children. Introducción. La contaminación en el hogar puede desempe ar un papel importante en el desarrollo y exacerbación del asma infantil, sobre todo entre ni os genéticamente predispuestos. Objetivos. Evaluar la asociación entre la presencia de contaminantes biológicos intradomiciliarios y síntomas indicativos de asma, en preescolares de Bucaramanga, Colombia Materiales y métodos. Se hizo un estudio de corte transversal analítico, en menores de 7 a os, en dos zonas de la ciudad con niveles diferentes de contaminación atmosférica por material particulado. Se evaluaron los síntomas respiratorios indicativos de asma y los contaminantes intradomiciliarios mediante cuestionarios previamente validados, las mediciones biológicas de ácaros y hongos por métodos de laboratorio estandarizados, y se usó el modelo log binomial para el análisis multivariado, que permitió evaluar asociaciones mediante la estimación de las razones de prevalencia. Resultados. Par
Seroprevalencia del virus de la hepatitis A en ni?os de 1 a 15 a?os en un hospital universitario
Ospina,Sigifredo; Becerra,María Gabriela; Aguirre,Carlos; Mari?o,Ana Cristina; Galvis,Clara Esperanza; Villarreal,María Inés; De la Hoz,Fernando; Méndez,Hernando; Sierra,Alexandra; López,Pío; Pérez,Jorge; Niederbacher,Jurg; Espinal,Carlos; Mojica,Alejandro;
Infectio , 2011,
Abstract: introduction: hepatitis a is an infectious disease caused by a non-encapsulated rna virus of the picornaviridae family, classified as hepatovirus. it is transmitted by a fecal-oral route, either from person to person or in common source epidemics. objective: the aim of this study was to estimate the seroprevalence of igg antibodies against the hepatitis a virus in children aged 1-15 years, treated in a university hospital as part of a national collaborative study. methods: a descriptive study was performed between june and november 2007. the antibody titers were detected by means of a microparticle capture enzyme immunoassay. a survey to identify risk factors was conducted for each participant, with additional variables under study. results: we studied 422 children. the overall prevalence of antibodies against hepatitis a was 29.1%, with 37.1% in the group of 5 to 9 years of age, 36.1% for 10 to 15, and 13.8% for 1 to 4. the highest proportion of antibody prevalence was found in children of the lowest socioeconomic status, 44.2% for the stratum 1 and 27.9% for the stratum 2. conclusion: the seroprevalence to hepatitis a virus was lower in children with less than five years of age, which is an indication of a transition of the epidemiological profile to an intermediate one. the prevalence was higher in children of low socioeconomic levels, which may be related to overcrowding and poor hygiene practices
Incidencia y factores asociados al síndrome sibilante del lactante, área Metropolitana de Bucaramanga, Colombia Incidence and associated factors to wheezing in infants, Bucaramanga Metropolitan Area, Colombia
Sandra Janneth Moreno,Jürg Niederbacher,José Fidel Latorre,Diana Carolina Archila
Revista de la Universidad Industrial de Santander. Salud , 2011,
Abstract: Introducción: Los cuadros broncoobstructivos en lactantes son causa frecuente de consulta a servicios ambulatorios, acudir a urgencias u hospitalización. Se presentan en forma recurrente o recidivante, con secuelas a largo plazo. Objetivo: Establecer la incidencia y los factores asociados para desarrollar síndrome sibilante (SS) y su recurrencia durante los dos primeros a os de vida. Metodología: Estudio retrospectivo de cohorte. Se indagó sobre presencia de sibilancias, edad de la primera crisis, eventos en los primeros dos a os de vida, y aspectos reconocidos previamente como factores de riesgo. Se estimó tasa de incidencia y probabilidad de estar libre de SS a los dos a os, así como los factores asociados con la presencia de SS recurrente y no recurrente. Resultados: Se estudiaron 139 varones y 159 ni as residentes en el área Metropolitana de Bucaramanga, Colombia. La tasa de incidencia a dos a os es de 1,22 episodios/100 meses-persona (IC95% 0,97-1,47), con probabilidad de llegar al segundo cumplea os sin SS es 67,0% (IC95% 60,7 a 72,4%). Los factores asociados con SS no recurrente fueron historia familiar de rinitis (RR 2,56) o asma (RR 2,11), y convivir con fumadores (RR 2,00); SS recurrente fueron historia familiar de rinitis (RR 8,79) o asma (RR 3,43), consumo de alimentos alergénicos (RR 6,82), asfixia perinatal (RR 6,36), asistir al jardín infantil (RR 3,37) y convivir con menores de 10 a os (RR 1,63). Discusión: La incidencia de SS es similar a la encontrada en países desarrollados. Muchos factores asociados son prevenibles, que de intervenirse ayudaría a disminuir el riesgo de que los lactantes enfermen o que recurran. Salud UIS 2011; 43 (2): 131-140 Introduction: Bronchoobstructive disease in infants is frequent cause of assistance to primary and emergency services, and hospitalization, too. These are recurrent or non-recurrent, with long-term sequelae. Objective: To establish the incidence and associated factors for developing wheezing syndrome (WS) and its recurrence during the first two years of life. Methodology: A retrospective cohort. A survey was conducted to determine wheezing incidence, age at first crisis, event number in the first two years of life, and aspects previously recognized as risk factors. It was estimated incidence rate and likelihood of being free of WS at two years, as well as the associated factors with recurrent and non-recurrent WS. Results: We studied 139 boys and 159 girls dwelling in the Bucaramanga Metropolitan Area, Colombia. The incidence rate for two years is 1.22 events/100 person-months (95%CI 0,97-1,47),
Roll of antibodies antiplatelets in viral infection: a systematic review of literature Papel de los anticuerpos antiplaquetarios en la infección viral: una revisión sistemática de la literatura
Yenny M. Montenegro-Medina,Luz Aída Rey-Caro,Jurg Niederbacher,Ruth Aralí Martínez-Vega
Biomédica , 2011,
Abstract: Introduction. Thrombocytopenia is a frequent phenomenon in viral infections. Peripheral platelet destruction mediated by anti-platelet antibodies has been one of the proposed causal mechanisms. Objective. Results were collected and analyzed from published studies on associations of human viral infections on anti-platelet antibodies and total platelet counts. Materials and methods. A PubMed search was conducted using the following terms: Viral infection (OR Virus diseases) AND antiplatelet antibody (OR thrombocytopenia) AND HIV (OR measles OR dengue OR chickenpox OR varicella OR Epistein Barr OR mumps OR rubella). Two hundred eighteen reference hits were obtained, 65 of which were relevant to this review. Results. Antiplatelet antibody-mediated thrombocytopenia has been documented in cases of HIV, measles, dengue, chickenpox, Epstein-Barr, mumps and rubella. Moreover, the presence of these antibodies has been associated with severity the disease and thrombocytopenia in viral infections. Conclusions. Although the presence of antiplatelet antibodies was not the only mechanism for explaining the thrombocytopenia developed in these viral infections, their presence was associated with severity of thrombocytopenia and with the clinical presentation of these patients. Introducción. La trombocitopenia es un fenómeno frecuente en las infecciones virales. Uno de los mecanismos propuesto como posible explicación de su desarrollo es la destrucción plaquetaria periférica mediada por anticuerpos antiplaquetarios. Objetivo. Revisar los resultados de los trabajos originales que existen en la literatura sobre infección viral y anticuerpos antiplaquetarios en humanos, y su efecto sobre el recuento total de plaquetas. Materiales y métodos. Se hizo una búsqueda en PubMed empleando la combinación de términos: "viral infection (OR Virus diseases) AND antibody antiplatelet (OR thrombocytopenia); y antibody antiplatelet AND HIV (OR Measles, OR Dengue, OR Chickenpox OR varicella, OR Epstein Barr, OR Mumps, OR Rubella". Se obtuvieron 218 referencias, de las cuales, 65 correspondían al objetivo de la revisión. Resultados. En la búsqueda se encontró que la trombocitopenia mediada por anticuerpos antiplaquetarios se ha documentado en infecciones virales por VIH, sarampión, dengue, varicela-zóster, Epstein-Barr, parotiditis y rubéola. La presencia de anticuerpos antiplaquetarios en infecciones virales por VIH, virus de Epstein-Barr y dengue, se ha asociado con la presencia de la trombocitopenia y con la gravedad de la enfermedad. Conclusiones. Aunque la aparición de anticuerpos antip
A Graph-Theoretical Approach to Calculate Vibrational Energies of Atomic and Subatomic Systems  [PDF]
Jorge Galvez
Open Journal of Physical Chemistry (OJPC) , 2012, DOI: 10.4236/ojpc.2012.24028
Abstract: One of the challenges still pending in string theory and other particle physics related fields is the accurate prediction of the masses of the elementary particles defined in the standard model. In this paper an original algorithm to assign graphs to each of these particles is proposed. Based on this mapping, we demonstrate that certain indices associated with the topology of the graph (graph theoretical indices) are very effective in predicting the masses of the particles. Specifically, the spectral moments of the graph adjacency matrix weighted by edge degrees play a key role in the excellent correlations found. Moreover, the same topological pattern is found in other well known quantum systems such as the particle in a box and the vibrational frequencies of diatomic molecules, such as hydrogen. The results shown here open a suggestive pathway for the use of graph-theoretical approaches in predicting properties of elementary particles and other physical systems, which seem to match similar topological patterns.
Environmental Impact Assessment of the Application of Pyrogenic Carbon in Soil  [PDF]
Jorge Laine
Journal of Environmental Protection (JEP) , 2013, DOI: 10.4236/jep.2013.410137
Abstract:

World increasing population and use of energy for transportation and electricity are demanding more extensive and more efficient use of land for agriculture; aiming to both food and biofuel supplies. This communication assesses the possible improvements in soil fertility, capture of greenhouse gas, and rainfall, as a result of the large scale terrestrial application of pyrogenic carbon aiming for desert greening. Fossil hydrocarbon coke is taken into account for this proposal because of the exhaustion of light petroleum proven reserves that is leading to a scenario of abundant coke production from the processing of non-conventional reserves.

Development of a “Space-Saving Model” for a One-Family Dwelling Case Study of Japanese Architecture with Space Limitations  [PDF]
Jorge Romero
Journal of Building Construction and Planning Research (JBCPR) , 2015, DOI: 10.4236/jbcpr.2015.34020
Abstract: The rapid globalization of building standards and codes in regards of contemporary housing and the growth of populations during this century demands an immediate response from designers in terms of space rationalizing to fulfill the forthcoming lack of architectural habitat on earth. The differences in culture imply a difference in the way of living, and the way of living indicates a contrast in the way of designing houses. A western house does not need an extra room covered with tatami mats for relaxation as a modern Japanese home would most likely do, as a separate living-like space. Organizations, among others, like CABO (Council of American Building Officials) and, in our specific case study, BCJ (Building Center of Japan) together with BRI (Building Research Institute) try to overcome these differences to provide better housing conditions to the world through the formulation of global designing and building standards. International publications like UBC (Uniform Building Code), IBC (International Building Code), OTFDC (One and Two Family Dwelling Code) and BSLJ (Building Standard Law of Japan) have also played an important role to globalize safety and design codes to better understand global housing under normal conditions. However, space limitations and concentration of human masses in mega cities result in a crucial new consideration: the urgent need of investigating the possibilities of rationally living within less space. Minimums provided by most codes do not take into account the space issue and overpopulation of large cities. Providing with some design recommendations for one-family dwellings has been the departure point and main motivation to carry out this case study based on actual buildings with the lack of space conditioning in a country where these conditions turn into reality.
Speech Assessment for UIDE EFL Students: The IPA Case
—General-American English IPA Transcription to Assess Universidad Internacional del Ecuador EFL Students
 [PDF]

Jorge Romero
Open Journal of Modern Linguistics (OJML) , 2016, DOI: 10.4236/ojml.2016.62005
Abstract: This Teaching English as the target second language involves several considerations which have to do with both the source language of speakers and the kind of training these students go through. In this particular case study, I have considered native speakers of Spanish who study English as a second language and identified, through two vowel sounds forming a minimal pair, that phonemes of General American English which are more likely to be mispronounced, is not only due to the fact that the English vowel system is more complex than that of Spanish, but also, and most important for this particular case study, that training is not consistent in contrastive exercising as it is in distribution exercising. In fact the English system has 20 vowel phonemes in Received Pronunciation, from 14 to 16 vowel phonemes in General American English and even 20 to 21 vowel phonemes in Australian English, while Spanish has only 5 vowel phonemes. The findings of this research account for the conclusion that exercising reinforcement need to be addressed and focused not only on the phonemes of the English vowel system which native speakers of Spanish have more trouble with, but also and more relevant in this research, that new and creative distribution exercising must be included in textbooks to help students master the English vowel sounds in order to avoid accent due to Spanish interference through quality English teaching.
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