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Search Results: 1 - 10 of 74743 matches for " John-Michael Kuczynski "
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A quasi-materialist, quasi-dualist solution to the mind-body problem
Kuczynski, John-Michael;
Kriterion: Revista de Filosofia , 2004, DOI: 10.1590/S0100-512X2004000100005
Abstract: if the mental can affect, or be affected by, the physical, then the mental must itself be physical. otherwise the physical world would not be explanatorily closed. but it is closed. there are reasons to hold that materialism (in both its reductive and non-reductive varieties) is false. so how are we to explain the apparent responsiveness of the physical to the mental and vice versa? the only possible solution seems to be this: physical objects are really projections or isomorphs of objects whose essential properties are mental. (a slightly less accurate way of putting this would be to say: the constitutive - i.e. the non-structural and non-phenomenal - properties of physical objects are mental, i.e. are such as we are used to encountering only in "introspection".) the chair, qua thing that i can know through sense perception, and through hypotheses based strictly thereupon, is a kind of shadow of an object that is exactly like it, except that this other objects essential properties are mental. this line of thought, though radically counterintuitive, explains the apparent responsiveness of the mental to the physical, and vice versa, without being open to any of the criticisms to which materialism, dualistic interaction ism, and epiphenomenalism are open.
Non-Declarative Sentences and the Theory of Definite Descriptions
John-Michael Kuczynski
Principia : an International Journal of Epistemology , 2004,
Abstract: This paper shows that Russell’s theory of descriptions gives the wrong se-mantics for definite descriptions occurring in questions and imperatives. Depending on how that theory is applied, it either assigns nonsense to per-fectly meaningful questions and assertions or it assigns meanings that di-verge from the actual semantics of such sentences, even after all pragmatic and contextual variables are allowed for. Given that Russell’s theory is wrong for questions and assertions, it must be wrong for assertoric state-ments; for the semantics of ‘the phi’ obviously doesn’t vary depending on whether it occurs in a question or an assertion or a command.
Davidson on Turing: Rationality Misunderstood?
John-Michael Kuczynski
Principia : an International Journal of Epistemology , 2005,
Abstract: Alan Turing advocated a kind of functionalism: A machine M is a thinker provided that it responds in certain ways to certain inputs. Davidson argues that Turing’s functionalism is inconsistent with a cer-tain kind of epistemic externalism, and is therefore false. In Davidson’s view, concepts consist of causal liasons of a certain kind between subject and object. Turing’s machine doesn’t have the right kinds of causal li-asons to its environment. Therefore it doesn’t have concepts. Therefore it doesn’t think. I argue that this reasoning is entirely fallacious. It is true that, in some cases, a causal liason between subject and object is part of one’s concept of that object. Consequently, to grasp certain propositions, one must have certain kids of causal ties to one’s environment. But this means that we must rethink some old views on what rationality is. It does not mean, pace Davidson, that a precondition for being rational is being causally embedded in one’s environment in a certain way. If Tur-ing’s machine isn’t capable of thinking (I leave it open whether it is or is not), that has nothing to do with its lacking certain kinds of causal con-nections to the environment. The larger significance of our discussion is this: rationality consists either in one’s ability to see the bearing of purely existential propositions on one another or rationality is simply not to be understood as the ability see the bearing that propositions have on one another.
Retroperitoneal High Grade Undifferentiated Pleomorphic Sarcoma as a Second Metachronous Neoplasm Following Intracranial Meningioma  [PDF]
Armin Kamyab, Michael John Jacobs
Journal of Cancer Therapy (JCT) , 2011, DOI: 10.4236/jct.2011.24070
Abstract: Introduction: Meningiomas and retroperitoneal sarcomas are two distinct rare tumors, with an incidence of 2 and 0.4 cases per 100,000 respectively. Case Report: We report the case of a 39 year old woman with a history of intracranial meningioma who was found two months later to have a large retroperitoneal sarcoma on CT scan after presenting to the emergency department complaining of abdominal pain. Pathologic evaluation was consistent with a high grade undifferentiated sarcoma. Discussion: It is highly unusual for a 39 year old otherwise healthy patient to present with two rare, seemingly unrelated tumors. It is our suspicion that there is a genetic component involved, however to date no association has been described in the literature between intracranial meningiomas and extracranial sarcomas. Conclusion: Besides being the first report of a retroperitoneal sarcoma occurring as a second metachronous neoplasm following an intracranial meningioma, we suspect that there is a genetic component involved. Further studies may indicate a genetic mutational link.
The Biological Observation Matrix (BIOM) format or: how I learned to stop worrying and love the ome-ome
Daniel McDonald, Jose C Clemente, Justin Kuczynski, Jai Rideout, Jesse Stombaugh, Doug Wendel, Andreas Wilke, Susan Huse, John Hufnagle, Folker Meyer, Rob Knight, J Caporaso
GigaScience , 2012, DOI: 10.1186/2047-217x-1-7
Abstract: The BIOM file format is supported by an independent open-source software project (the biom-format project), which initially contains Python objects that support the use and manipulation of BIOM data in Python programs, and is intended to be an open development effort where developers can submit implementations of these objects in other programming languages.The BIOM file format and the biom-format project are steps toward reducing the “bioinformatics bottleneck” that is currently being experienced in diverse areas of biological sciences, and will help us move toward the next phase of comparative omics where basic science is translated into clinical and environmental applications. The BIOM file format is currently recognized as an Earth Microbiome Project Standard, and as a Candidate Standard by the Genomic Standards Consortium.Advances in DNA sequencing have led to exponential increases in the quantity of data available for “comparative omics” analyses, including metagenomics (e.g., [1,2]), comparative genomics (e.g., [3]), metatranscriptomics (e.g., [4,5]), and marker-gene-based community surveys (e.g., [6,7]). With the introduction of a new generation of "benchtop sequencers" [8], accessible to small research, clinical, and educational laboratories, sequence-based comparative omic studies will continue to increase in scale. The rate-limiting step in many areas of comparative omics is no longer obtaining data, but analyzing that data (the “bioinformatics bottleneck”) [9,10]. One mechanism that will help reduce this “bioinformatics bottleneck” is standardization of common file formats to facilitate sharing and archiving of data [11].As with the increasing prevalence of high-throughput technologies in the biological sciences, the categories of comparative omics data, which we collectively term the “ome-ome”, are rapidly increasing in number (Figure 1). Researchers are relying on more types of omics data to investigate biological systems, and the coming years will bri
Comparison and Evaluation of Power Factor Correction Topologies for Industrial Applications  [PDF]
John Karatzaferis, Nick Papanikolaou, Emmanuel Tatakis, Michael Loupis, John Spanoudakis
Energy and Power Engineering (EPE) , 2013, DOI: 10.4236/epe.2013.56042

Power factor correction is a major issue for all industries, since a typical industrial load is causing current delays, as well as higher order current harmonics. Power factor correction is often mandatory from the power companies, usually by charging the reactive power that the company consumes. Many solutions for power factor correction have been presented in the bibliography; in this paper, the most significant power factor correction topologies will be reviewed and simulated with SABER RD software. Finally, a prototype design will be presented, based on a mass/cost analysis of the selected topologies and with an aim to manufacture 10 kW modules. The main outcome of this work is the feasibility for an SME to manufacture a competitive modular power factor correction product for industrial applications.

Classification of River Reaches on the Little Disturbed East Alligator River, Northern Australia  [PDF]
Michael John Saynor, Wayne D. Erskine
International Journal of Geosciences (IJG) , 2013, DOI: 10.4236/ijg.2013.46A2007

The East Alligator River drains a 7000 km2 catchment in northern Australia comprised largely of Aboriginal land and has a very low average population density of about 0.15 persons per km2. River reaches were classified according to geomorphic features on both the East Alligator River and its major tributary, Magela Creek, next to which is located the Ranger uranium mine. Sixteen reaches were described for the 241.4 km of the East Alligator River and ten reaches were described for the 118.8 km of Magela Creek. The dominant river types on the East Alligator River were various types of anabranching rivers, sandstone gorges and cuspate tidal meanders. On Magela Creek the dominant river types were wetlands and channel billabongs, island anabranching and sandstone gorges. It is unusual for anabranching rivers and gorges to be so dominant. Current river classification schemes could not accommodate all the various river types and need to be modified so that tidal channels are covered in more detail and so that the classification of anabranching rivers recognises that sand-bed varieties occur in partly confined valley settings.

Luminous Shapes with Unusual Motions as Potential Predictors of Earthquakes: A Historical Summary of the Validity and Application of the Tectonic Strain Theory  [PDF]
Michael A. Persinger, John S. Derr
International Journal of Geosciences (IJG) , 2013, DOI: 10.4236/ijg.2013.42037

For centuries and on every continent discrete shapes of lights with unusual motions have preceded earthquakes. The numbers of these lights per interval within a region have been strongly correlated with the amount of seismic energy subsequently released within that region. These temporal intervals range between 3 months and 6 months for areas more than 500 kmin radius and less than a month for smaller radii. Other analyses have shown that the same tectonic strain associated with earthquakes is also associated with the display of luminous events before those earthquakes. This strain can be precipitated by injections of fluids into the crust, natural changes in hydrological loads on rivers, or, purposeful displacement of water into reservoirs. The strengths of the associations are sufficient to allow modest forecasting of earthquakes within the boundaries of the region and the temporal interval of analysis. More accurate utilization of these phenomena as prognosticators of specific earthquakes will require a re-evaluation of the manner by which these data are systematically recorded and interpreted.

Mixed Band Control of Mutual Proportional Reinsurance  [PDF]
Michael Taksar, John Liu, Jiguang Yuan
Journal of Mathematical Finance (JMF) , 2013, DOI: 10.4236/jmf.2013.32025

In this paper, we investigate the optimization of mutual proportional reinsurance—a mutual reserve system that is in- tended for the collective reinsurance needs of homogeneous mutual members, such as P&I Clubs in marine mutual in- surance and reserve banks in the US Federal Reserve, where a mutual member is both an insurer and an insured. Compared to general (non-mutual) insurance models, which involve one-sided impulse control (i.e., either downside or upside impulse) of the underlying insurance reserve process that is required to be positive, a mutual insurance differs in allowing two-sided impulse control (i.e., both downside and upside impulse), coupled with the classical proportional control of reinsurance. We prove that a special band-type impulse control (a, A, B, b) with a=0 and a<A<B<b, coupled with a proportional reinsurance policy (classical control), is optimal when the objective is to minimize the total maintenance cost. That is, when the reserve position reaches a lower boundary of a=0, the reserve should immedi- ately be raised to level A; when the reserve reaches an upper boundary of b, it should immediately be reduced to a level B. An interesting finding produced by the study reported in this paper is that there exists a situation such that if the up-

Hyperthermic Intraperitoneal Chemotherapy (HIPEC) and Intraoperative Electrolyte Disturbances—Implications for Anesthetic Management  [PDF]
John L. Raytis, Michael W. Lew
Open Journal of Anesthesiology (OJAnes) , 2014, DOI: 10.4236/ojanes.2014.410036
Abstract: The administration of hyperthermic intraperitoneal chemotherapy (HIPEC) is often associated with significant intraoperative electrolyte changes. We retrospectively examined the pre-HIPEC and post-HIPEC intraoperative basic metabolic panel (BMP) values of the 20 patients who underwent HIPEC at our institution between December 2009 and January 2012. For the five patients who underwent HIPEC with oxaliplatin in 5% dextrose in water (D5W), there were statistically significant changes between the pre- and post-HIPEC values of sodium (135 to 124 mmol/L), chloride (105 to 94 mmol/L), glucose (143 to 388 mg/dl) and sodium corrected for hyperglycemia (135 to 127 mmol/L). For the 14 patients who received HIPEC with mitomycin C in normal saline (NS), there were statistically significant changes in bicarbonate (24 to 21 meQ/L), blood urea nitrogen (BUN) (10 to 9 mg/dl) and glucose (158 to 134 mg/dl). The BMP changes for the one patient who received doxorubicin/cisplatin in peritoneal dialysate are reported separately.
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