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Search Results: 1 - 10 of 33954 matches for " John Dean "
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Edsel Ford: The Businessman as Artist
John Dean
Transatlantica : Revue d'études Américaines , 2011,
Abstract: This essay’s objective is to examine an overlooked, outstanding example of the businessman as artist, Edsel Bryant Ford. To consider his skill as automobile designer; his forceful, innovative management of advertising and public relations; his adept painting, sculpting and photography; his exceptional sense of personal elegance; the creation by his wife and himself of a remarkable personal residence; his philanthropic enterprises; his challenging, adroit and often deeply frustrating dealings ...
The Businessman as Artist in American Civilization
John Dean
Transatlantica : Revue d'études Américaines , 2011,
Abstract: This Transatlantica dossier tries to offer the reader a concise, provocative gathering of questions, subjects, and possible answers to a core issue of American Civilization—the dynamic tension between profit and creativity, money and the muse. A great deal of orthodox social and aesthetic analysis since the advent of the industrial revolution has understood business and art to be at odds with each other. Many an artist in Anglo-American Civilization and elsewhere have not been comfortable wit...
The Businessman as Artist: The Subject Itself
John Dean
Transatlantica : Revue d'études Américaines , 2011,
Abstract: Take The MeasureCreating, Producing, CreatingWhy care about what the businessman and the artist have to do with one another? Because it is a relation that puts at issue the doer and the thinker, the realist and idealist, the pragmatist and the dreamer. And a rock basic question like: which comes first, money or creativity?When Harry B. and Jack Warner corralled, nursed, pampered, bullied and produced artistic output at their studios from the 1920s onward, were they just puppet masters puling ...
The Social and Cultural Construction of Abraham Lincoln in U.S. Movies and on U.S. TV
John Dean
American Studies Journal , 2009,
Abstract: Abraham Lincoln has constantly moved among and stirred Americans in the common, shifting ground of their popular, visual, and digital imagination. Nowadays, Lincoln is larger than the sum of his parts. This is due partly to his own prismatic personality, partly to his political genius, partly to the special needs of the American nation and its people. If Lincoln did not exist, someone, somehow, would have tried to construct a representative figure who came close to the mark of what the Civil War, the fight for Union, the failure of Succession, the liberty of the slaves and the material-spiritual expansion of America meant. But Lincoln existed. Lincoln hit the target. Here was witness, cause, martyr and lodestone all packed into one.
Adapting History and Literature into Movies
John Dean
American Studies Journal , 2009,
Abstract: This essay tries to offer an overview of adaptation, an initiation into this subject for the educated reader who is not a communications or film specialist. The essay will reference "The Social and Cultural Construction of Abraham Lincoln in U.S. Movies and on U.S. TV”—but mainly with an eye to the larger issue of cinematographic adaptation itself.
Appendix: The Mechanics of Books versus the Mechanics of Movies
John Dean
American Studies Journal , 2009,
Abstract: An end product is the result of a process. The design, construction, and use of books and movies depend each upon the particular dynamics of how they come into existence. Here is an outline of how they are made.
Multiscale Modelling for Cerebrospinal Fluid Dynamics: Multicompartmental Poroelacticity and the Role of AQP4  [PDF]
Dean Chou, John C. Vardakis, Yiannis Ventikos
Journal of Biosciences and Medicines (JBM) , 2014, DOI: 10.4236/jbm.2014.22001

Cerebrospinal fluid (CSF) is recognized to play an important role in the brain environment and central nerv-ous system (CNS). At the microscopic level, glial cells and water channel proteins (WCPs), also known as aquaporins (AQPs), are believed to be central in regulating CSF. Furthermore, such elements are postulated to associate with numerous cerebral and neurological pathologies. The novelty of the present research is the attempt to investigate such pathophysi-ological phenomena via a multi scale physical model incorporating mechanisms across all scales, including the AQP effects. The proposed physical multiscale model can explore the relationship between CSF and glial cells via the incorporation of AQPs (as microscopic channels) and elaborate on the macroscopic manifestations of this interplay. This study aims to make a tangible contribution to the understanding of cerebral or neurological pathologies via virtual physiological human (VPH) in silico.

Cerebellar Motor Learning: When Is Cortical Plasticity Not Enough?
John Porrill,Paul Dean
PLOS Computational Biology , 2007, DOI: 10.1371/journal.pcbi.0030197
Abstract: Classical Marr-Albus theories of cerebellar learning employ only cortical sites of plasticity. However, tests of these theories using adaptive calibration of the vestibulo–ocular reflex (VOR) have indicated plasticity in both cerebellar cortex and the brainstem. To resolve this long-standing conflict, we attempted to identify the computational role of the brainstem site, by using an adaptive filter version of the cerebellar microcircuit to model VOR calibration for changes in the oculomotor plant. With only cortical plasticity, introducing a realistic delay in the retinal-slip error signal of 100 ms prevented learning at frequencies higher than 2.5 Hz, although the VOR itself is accurate up to at least 25 Hz. However, the introduction of an additional brainstem site of plasticity, driven by the correlation between cerebellar and vestibular inputs, overcame the 2.5 Hz limitation and allowed learning of accurate high-frequency gains. This “cortex-first” learning mechanism is consistent with a wide variety of evidence concerning the role of the flocculus in VOR calibration, and complements rather than replaces the previously proposed “brainstem-first” mechanism that operates when ocular tracking mechanisms are effective. These results (i) describe a process whereby information originally learnt in one area of the brain (cerebellar cortex) can be transferred and expressed in another (brainstem), and (ii) indicate for the first time why a brainstem site of plasticity is actually required by Marr-Albus type models when high-frequency gains must be learned in the presence of error delay.
Silent Synapses, LTP, and the Indirect Parallel-Fibre Pathway: Computational Consequences of Optimal Cerebellar Noise-Processing
John Porrill ,Paul Dean
PLOS Computational Biology , 2008, DOI: 10.1371/journal.pcbi.1000085
Abstract: Computational analysis of neural systems is at its most useful when it uncovers principles that provide a unified account of phenomena across multiple scales and levels of description. Here we analyse a widely used model of the cerebellar contribution to sensori-motor learning to demonstrate both that its response to intrinsic and sensor noise is optimal, and that the unexpected synaptic and behavioural consequences of this optimality can explain a wide range of experimental data. The response of the Marr-Albus adaptive-filter model of the cerebellar microcircuit to noise was examined in the context of vestibulo-ocular reflex calibration. We found that, when appropriately connected, an adaptive-filter model using the covariance learning rule to adjust the weights of synapses between parallel fibres and Purkinje cells learns weight values that are optimal given the relative amount of signal and noise carried by each parallel fibre. This optimality principle is consistent with data on the cerebellar role in smooth pursuit eye movements, and predicts that many synaptic weights must be very small, providing an explanation for the experimentally observed preponderance of silent synapses. Such a preponderance has in its turn two further consequences. First, an additional inhibitory pathway from parallel fibre to Purkinje cell is required if Purkinje cell activity is to be altered in either direction from a starting point of silent synapses. Second, cerebellar learning tasks must often proceed via LTP, rather than LTD as is widely assumed. Taken together, these considerations have profound behavioural consequences, including the optimal combination of sensori-motor information, and asymmetry and hysteresis of sensori-motor learning rates.
Small Seifert-fibered Dehn surgery on hyperbolic knots
John C. Dean
Mathematics , 2003, DOI: 10.2140/agt.2003.3.435
Abstract: In this paper, we define the primitive/Seifert-fibered property for a knot in S^3. If satisfied, the property ensures that the knot has a Dehn surgery that yields a small Seifert-fibered space (i.e. base S^2 and three or fewer critical fibers). Next we describe the twisted torus knots, which provide an abundance of examples of primitive/Seifert-fibered knots. By analyzing the twisted torus knots, we prove that nearly all possible triples of multiplicities of the critical fibers arise via Dehn surgery on primitive/Seifert-fibered knots.
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