Publish in OALib Journal
APC: Only $99
Mentoring has been identified as a valuable tool for learning and career development, as well as organizational advancement. E-mentoring has increased in popularity as a means of creating global access to mentors while reducing organizational training costs, and reducing both time and geographical constraints for mentors and mentees. E-mentoring has proven to most benefit the mentee and mentor when mutual trust has been established. However, e-mentoring is still a relatively new phenomenon and it is unclear how online trust is established and sustained between mentors and mentees. This paper presents a research agenda to better understand how trust is formed in e-mentoring.
Small RNAs are found in eukaryotes and are responsible for regulation of chromatin structure, RNA processing and stability, translation and transcription. 24-nt small interfering RNA (siRNA) are known to mediate gene inactivation via the RNA-directed DNA methylation pathway (RdDM) and are important for natural heritable changes in plant species. DNA cytosine methylation can be maintained between generations and this may be important for accelerated adaption to stress conditions. Research is currently focused toward the epigenetic response to disease, the stability of DNA methylation over generations, the elucidation of newly discovered pathways for de novo DNA methylation, and the application of epigenetic variation to breeding programs. This review aims to give a brief but comprehensive examination on small RNAs and transgenerational epigenetic variation.
Introduction: Motion sensors are mechanical and
electronic devices, which detect the body movement and provide an estimate of
physical activity in children and adults. However, they need to be validated
against criterion methods such as direct observation. The purpose of this study
was to validate a wrist worn accelerometer to quantify the physical activity of
children, by comparison to direct observation using the Children’s Activity
Rating Scale (CARS). Materials and Methods: Data were recorded from 42
children, aged 3 - 5 years (22 boys and 20 girls), of whom each was observed
each minute for 2 hours using Children’s Activity Rating Scale (CARS) while
they wore the Actiwatch. Results: The CARS score and activity counts from the
accelerometer were averaged over 1- to 10-minute periods across all individuals.
There was a significant positive correlation between the mean CARS scores and
the mean Actiwatch counts over simultaneous 1- to 10-minute periods ranging
from r = 0.41 to r = 0.63 (P < 0.001). To assess validity of the data, a
cross validation method was applied. There was no significant difference between the predicted and the observed CARS scores in
the validation sample. Given the data from the Actiwatch (averaged over a
5-minute epoch), the equivalent CARS score could be calculated with a 95% confidence
level of plus or minus 0.74 CARS units. Conclusion: These data suggest that the
Actiwatch (a wrist worn accelerometer) is a valid tool for assessing levels of
physical activity in young children.