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Search Results: 1 - 10 of 25459 matches for " Jo Nadine Fleming "
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Cutaneous Chronic Graft-Versus-Host Disease Does Not Have the Abnormal Endothelial Phenotype or Vascular Rarefaction Characteristic of Systemic Sclerosis
Jo Nadine Fleming,Howard M. Shulman,Richard A. Nash,Pamela Y. Johnson,Thomas N. Wight,Allen Gown,Stephen M. Schwartz
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0006203
Abstract: The clinical and histologic appearance of fibrosis in cutaneous lesions in chronic graft-versus -host disease (c-GVHD) resembles the appearance of fibrosis in scleroderma (SSc). Recent studies identified distinctive structural changes in the superficial dermal microvasculature and matrix of SSc skin. We compared the dermal microvasculature in human c-GVHD to SSc to determine if c-GVHD is a suitable model for SSc.
Exploring the Relationship between Obstetrical Nurses’ Work and Pregnancy Outcomes  [PDF]
Jo Watson, Monica Nicholson, Kelly Dobbin, Karen Fleming, Julia M. K. Alleyne
Open Journal of Nursing (OJN) , 2016, DOI: 10.4236/ojn.2016.69080
Abstract: The Registered Nurses Association of Ontario Healthy Work Environments Best Practice Guideline recommends that employers promote safe, healthy workplaces. Healthy workplaces include addressing the unique needs of nurses who work while pregnant. The purpose of this descriptive study, summarizing information from 120 pregnancies reported by 95 nurses, was to determine if the workload of obstetrical nurses was associated with negative pregnancy outcomes, including preterm delivery and birth weight. Full-time obstetrical nursing work is a predictor of reduced birth weight, but not of preterm birth when compared to outcomes of obstetrical nurses working part time. One third of nurses reported pregnancy complications and most nurses experienced work-related and personal stress. Further research evaluating work modifications during pregnancy is indicated to improve birth outcomes.
Ego Depletion and the Humean Theory of Motivation  [PDF]
Patrick Fleming
Open Journal of Philosophy (OJPP) , 2014, DOI: 10.4236/ojpp.2014.43042

By what capacities do human beings engage in intentional action? Humeans about motivation claim that the source of all action is desire. Volitionalists claim that action has two distinct sources, one in the will and one in desire. Recent work suggests that volitionalism has some empirical support. Roy F. Baumeister and colleagues have argued for a phenomenon called “ego depletion”. They argue that some aspect of the self exerts volition in a number of different contexts. The main evidence for this claim is that experimental subjects who engage in acts of self-regulation are less likely to engage in similar actions on later tests. The evidence calls for a reformulation of the Humean theory, not a rejection of it. And the reformulation is one that still has interest for metaethics. Many philosophers are interested in the Humean theory of motivation because they believe that it has implications for the correct theory of normative practical reasons. Here I argue that if the Humean theory of motivation was ever a threat to the objectivity of morality, it still is.

Mitochondrial/Nuclear Superstructures Drive Morphological Changes in Endometrial Epithelia by Pressure Exerted when Gas Vacuoles Form and Coalesce within Superstructures  [PDF]
Honoree Fleming
Advances in Bioscience and Biotechnology (ABB) , 2018, DOI: 10.4236/abb.2018.95016
Abstract: Mitochondria, usually ovoid structures no larger than 0.5 microns can fuse into structures that are 5 microns and larger such as nebenkern, spheroidal or cup-shaped mitochondria, and even mega-mitochondria. In studying differentiation of human endometrial epithelial cells, it became clear that formation of mitochondrial superstructures was an essential part of the process. In this paper, the origins, function, and demise of these superstructures called mitonucleons are described. In the course of reading papers about mitochondrial superstructures, it became obvious that there are important similarities, particularly with regard to function, between the mitonucleon and the nebenkern, a superstructure essential for dramatic tail elongation during spermatogenesis in grasshoppers, drosophila, and other insects. Close inspection of photomicrographs of differentiating mitonucleons during the first 12 hours suggests that gases build up in vacuoles within the mitochondrial superstructure creating pressure that elevates syncytial membranes and compresses nuclear aggregates contained within the mitonucleon.
Combination (5% Hydroquinone, 0.1% Tretinoin and 1% Hydrocortisone) Cream in Treating Facial Hyperpigmentation: A Retrospective Patient Satisfaction Survey  [PDF]
John Fleming, Saqib Bashir
Journal of Cosmetics, Dermatological Sciences and Applications (JCDSA) , 2014, DOI: 10.4236/jcdsa.2014.45043
Abstract: Background: Melasma and post-inflammatory hyperpigmentation provide a significant source of psychosocial morbidity, especially in those with Fitzpatrick skin types III-VI. In Europe, a proprietary product aimed at treating these conditions, similar to Kligman’s formula but with a longer expiry date, has become available. Objectives: To assess patient satisfaction with a newly available combination de-pigmenting preparation. Methods: We conducted a small study to see if patients felt that this new product affected their quality of life and skin symptoms from hyperpigmentation. 41 subjects, who had all been prescribed a 15 g tube to use sparingly at night for 90 days within the last 12 months were telephoned to rate the effect the cream had on their quality of life and skin symptom improvement. Each patient also had their Dermatology Life Quality Index (DLQI) score assessed. Results: Out of the 29 patients who responded to the study, 22 had melasma and 7 had post-inflammatory hyperpigmentation from acne. 21 subjects felt that the cream made either a marked or moderate improvement on their quality of life and 23 subjects felt that the cream made either a marked or moderate improvement on their skin symptoms. Conclusion: Patients reported improvement in both hyperpigmentation and quality of life, suggesting a high level of satisfaction with treatment. The long shelf life of the product may also promote compliance and reduce health-care costs.
Creativity as Central to Critical Reasoning and the Facilitative Role of Moral Education: Utilizing Insights from Neuroscience  [PDF]
Terence Lovat, Daniel Fleming
Creative Education (CE) , 2015, DOI: 10.4236/ce.2015.611108
Abstract: The article will review the literature of updated neuroscientific research in order to gain insights into the centrality to critical reasoning of creativity (understood as creative thinking, including the impulsion of imagination and wonder). Furthermore, it will explore literature that testifies to the credentials of moral education in facilitating the forms of creativity associated with the development of critical reasoning, as suggested by the insights of neuroscience. Finally, the article will review the literature related to earlier empirical evidence of the crucial role that moral education can play in facilitating creativity, imagination and wonder.
Studying Heavy Metals in Sediments Layers along Selected Sites on the Lebanese Coast  [PDF]
Journal of Water Resource and Protection (JWARP) , 2010, DOI: 10.4236/jwarp.2010.21006
Abstract: Ensuring the environmental protection of the Lebanese coast requires a continues monitoring system. For this purpose, four heavy metals (Fe, Mn, Cu and Pb in the marine sediments along the Lebanese coast were selected for analysis Sampling was carried out from two sites: Beirut and Batroun. Thus, 1g of dried sample is used for digestion by wet mineralization in order to determine the concentration of the four heavy metals by atomic absorption spectrometry. The results showed that Beirut area is polluted, by Fe and Mn as well as the station Bat 2 of Batroun. For Cu and Pb, Batroun region is more polluted in the superficial layers. The analysis also showed significant difference between the sites except for Cu. A difference between depths and between particles size fractions are observed for all the parameters studied. There is no a significant difference in layer sequence except for the Pb, and neither between the repetitions of the same sample. Results showed that the values of the four metals studied do not exceed the maximum limits at both sites, but they showed increase in comparison with the analyses obtained before July 2006 conflict, which was caused by the release of large quantity of fuel-oil from Jiyeh Power Station.
Influence of production processes in quality of fermented milk "Laban" in Lebanon  [PDF]
Zeineddine Mayssoun, Nassif Nadine
Health (Health) , 2010, DOI: 10.4236/health.2010.24057
Abstract: Yoghurt (Laban) is one of the most consumed food products in Lebanon. Thus its quality has given a concern. In this study, the sensory, chemical and rheological properties of commercial and traditional samples were investigated in order to characterize this fermented milk. Hence, Laban samples were collected from 14 areas in Lebanon; especially from mountainous regions and from the capital Beirut. Forty-two samples were provided by processing industry whether at small, medium, or large scale. A statistical analysis was carried out, and thus sensory and physicochemical properties were subjected to two approaches of variance analysis. Pearson correlation coefficients between attributes were also calculated. Both, the analyses of variance and correlations were conducted using SPSS 3. The physicochemical analysis and the microbiological analysis exhibit a significant effect of the date, and the manufacturing process. Also, the instrumental data showed no significant correlation between physicochemical and microbiological parameters, which indicates that they are completely independent. Moreover, the general appreciation of descriptive sensory analysis of products display that this appreciation is not dependant on the production process. It is also noticed that some sensory characteristics can be dread by instrumental measures. This research endorses the essential role of quality control for the manufacturing of yoghurt in Lebanon.
Preoccupation with Weight and Eating Patterns of Lebanese and Cypriot Female Students  [PDF]
Ioanna Katsounari, Nadine Zeeni
Psychology (PSYCH) , 2012, DOI: 10.4236/psych.2012.36073
Abstract: This comparative cross-cultural study explores the prevalence of preoccupation with weight and eating patterns among female university students in two distinct cultural contexts, Cyprus and Lebanon. Data was collected by means of self-administered questionnaires to 200 students from each culture. To gather the data for this study, the Dutch Eating Behavior Scale was used for the assessment of eating behaviors. Body Mass Index (BMI) and Weight directed behavior were also calculated. The Pearson Product-Moment Correlation Coefficient was used to determine whether there is a linear relationship between students’ BMI and eating behaviors. Findings suggested that with respect to culture and pre-occupation with weight, Cypriot students are more pre-occupied with their weight. However, Lebanese students received higher emotional and external eating scores. In addition, a positive relationship between Body Mass Index, restrained and emotional eating was found in both cultures Also, in both cultures there was a significant positive relationship between restrained and emotional eating, emotional and external eating. These findings suggest that in the Lebanese culture, eating dysfunction among women may be due to responsiveness to external and emotional cues while in the Cypriot culture may be due to an over pre-occupation with weight fuelled by sociocultural agents. Understanding the underlying causes of eating deviations and the existing elements in each culture which promote these deviations could lead to better prevention efforts in two societies where the rise in eating disturbances has been alarming.
“We Are Only as Strong as We Are United, as Weak as We Are Divided” a Dynamic Analysis of the Peer Support Networks in the Harry Potter Books  [PDF]
Goele Bossaert, Nadine Meidert
Open Journal of Applied Sciences (OJAppS) , 2013, DOI: 10.4236/ojapps.2013.32024

This research studied the concept of enacted peer support during adolescence by means of the Harry Potter Series. A network approach was used. Results indicated the importance of reciprocity and transitivity for enacted peer support during adolescence. Contrary to our expectations, gender, age and personality traits did not affect enacted peer support. No homophily effects based on gender and age were detected. However, students were found to be more supportive of students with similar personality traits. We hope this study adds to the current knowledge on peer support in adolescence and promotes the use of social theories and methods in literacy research.

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