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Search Results: 1 - 10 of 24059 matches for " Jinlin Jiang "
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Automated Scoring Research over 40 Years: Looking Back and Ahead
Jinlin Jiang,Wei Wei
Journal of Artificial Intelligence , 2012,
Abstract: This study reviews the developments of automated scoring systems and techniques over the past 40 years and the strengths and weaknesses of each technique are analyzed in detail. Results of the study showed that automated scoring systems are becoming more complicated and advanced by the integrated use of knowledge in natural language processing, statistics, information retrieval, corpus linguistics, etc. but they still have drawbacks in one or two aspects. The study provides some valuable insights into further studies in this line.
Microcystin-LR Induced Reactive Oxygen Species Mediate Cytoskeletal Disruption and Apoptosis of Hepatocytes in Cyprinus carpio L.
Jinlin Jiang, Zhengjun Shan, Weili Xu, Xiaorong Wang, Junying Zhou, Deyang Kong, Jing Xu
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0084768
Abstract: Microcystins (MCs) are a group of cyclic hepatotoxic peptides produced by cyanobacteria. Microcystin-LR (MC-LR) contains Leucine (L) and Arginine (R) in the variable positions, and is one of the most common and potently toxic peptides. MC-LR can inhibit protein phosphatase type 1 and type 2A (PP1 and PP2A) activities and induce excessive production of reactive oxygen species (ROS). The underlying mechanism of the inhibition of PP1 and PP2A has been extensively studied. The over-production of ROS is considered to be another main mechanism behind MC-LR toxicity; however, the detailed toxicological mechanism involved in over-production of ROS in carp (Cyprinus carpio L.) remains largely unclear. In our present study, the hydroxyl radical (?OH) was significantly induced in the liver of carp after a relatively short-term exposure to MC-LR. The elevated reactive oxygen species (ROS) production may play an important role in the disruption of microtubule structure. Pre-injection of the antioxidant N-acetyl-cysteine (NAC) provided significant protection to the cytoskeleton, however buthionine sulfoximine (BSO) exacerbated cytoskeletal destruction. In addition, the elevated ROS formation induced the expression of apoptosis-related genes, including p38, JNKa, and bcl-2. A significant increase in apoptotic cells was observed at 12 - 48 hours. Our study further supports evidence that ROS are involved in MC-LR induced damage to liver cells in carp, and indicates the need for further study of the molecular mechanisms behind MC-LR toxicity.
Proteomic Analysis of Hepatic Tissue of Cyprinus carpio L. Exposed to Cyanobacterial Blooms in Lake Taihu, China
Jinlin Jiang, Xiaorong Wang, Zhengjun Shan, Liuyan Yang, Junying Zhou, Yuanqin Bu
PLOS ONE , 2014, DOI: 10.1371/journal.pone.0088211
Abstract: With the rapid development of industry and agriculture and associated pollution, the cyanobacterial blooms in Lake Taihu have become a major threat to aquatic wildlife and human health. In this study, the ecotoxicological effects of cyanobacterial blooms on cage-cultured carp (Cyprinus carpio L.) in Meiliang Bay of Lake Taihu were investigated. Microcystins (MCs), major cyanobacterial toxins, have been detected in carp cultured at different experimental sites of Meiliang Bay. We observed that the accumulation of MCs in carp was closely associated with several environmental factors, including temperature, pH value, and density of cyanobacterial blooms. The proteomic profile of carp liver exposed to cyanobacterial blooms was analyzed using two-dimensional difference in-gel electrophoresis (2D-DIGE) and mass spectrometry. The toxic effects of cyanobacterial blooms on carp liver were similar to changes caused by MCs. MCs were transported into liver cells and induced the excessive production of reactive oxygen species (ROS). MCs and ROS inhibited protein phosphatase and aldehyde dehydrogenase (ALDH), directly or indirectly resulting in oxidative stress and disruption of the cytoskeleton. These effects further interfered with metabolic pathways in the liver through the regulation of series of related proteins. The results of this study indicated that cyanobacterial blooms pose a major threat to aquatic wildlife in Meiliang Bay in Lake Taihu. These results provided evidence of the molecular mechanisms underlying liver damage in carp exposed to cyanobacterial blooms.
On subordination for certain subclass of analytic functions
Liu Jinlin
International Journal of Mathematics and Mathematical Sciences , 1997, DOI: 10.1155/s016117129700029x
Abstract: In the present paper the class Pn[ ±,M] consisting of functions f(z)=z+ ¢ ‘k=n+1 ¢ akzz(n ¢ ‰ ¥1), which are analytic in the unit disc E={z:|z|<1} and satisfy the condition |f ¢ € 2(z)+ ±zf ¢ € 3(z) ¢ ’1| Keywords analytic --- starlike --- convex univalent --- subordination.
Magnetic fields in our Galaxy: How much do we know? (II) Halo fields and the global field structure
Jinlin Han
Physics , 2001, DOI: 10.1023/A:1013102711400
Abstract: I review the large scale global magnetic field structure of our Galaxy, using all information available for disk fields, halo fields and magnetic fields near the Galactic center (GC). In the local disk of our Galaxy, RM and dispersion measure (DM) data of nearby pulsars yield the strength of regular field as 1.8$\mu$G, with a pitch angle of about $8\degr$, and a bisymmetric spiral structure. There are at least four, maybe five, field reversals from the Norma arm to the outskirts of our Galaxy. In the thick disk or Galactic halo, large scale toroidal magnetic fields, with opposite field directions in the Southern and Northern Galaxy, have been revealed by the antisymmetric RM sky towards the inner Galaxy. This signature of the A0 dynamo-mode field structure is strengthened by the indication of a poloidal field of dipole form, that is the transition of the RM signs probably shifted from $l\sim0\degr$ to $l\sim+10\degr$. The local vertical field is probably a part of this dipole field. The field structure of the A0 dynamo-mode strikingly continues towards the region near the GC. In short, the magnetic fields in the Galactic disk have a bisymmetric spiral structure of primordial nature, while in the halo and near the GC the A0 dynamo seems to dominate, so that the fields consist of toroidal fields with opposite directions below and above the Galactic plane and poloidal fields of dipole form.
Magnetic fields in our Milky Way Galaxy and nearby galaxies
JinLin Han
Physics , 2012, DOI: 10.1017/S1743921313002561
Abstract: Magnetic fields in our Galaxy and nearby galaxies have been revealed by starlight polarization, polarized emission from dust grains and clouds at millimeter and submillimeter wavelength, the Zeeman effect of spectral lines or maser lines from clouds or clumps, diffuse radio synchrotron emission from relativistic electrons in interstellar magnetic fields, and the Faraday rotation of background radio sources as well as pulsars for our Milky Way. It is easy to get a global structure for magnetic fields in nearby galaxies, while we have observed many details of magnetic fields in our Milky Way, especially by using pulsar rotation measure data. In general, magnetic fields in spiral galaxies probably have a large-scale structure. The fields follow the spiral arms with or without the field direction reversals. In the halo of spiral galaxies magnetic fields exist and probably also have a large-scale structure as toroidal and poloidal fields, but seem to be slightly weaker than those in the disk. In the central region of some galaxies, poloidal fields have been detected as vertical components. Magnetic field directions in galaxies seem to have been preserved during cloud formation and star formation, from large-scale diffuse interstellar medium to molecular clouds and then to the cloud cores in star formation regions or clumps for the maser spots. Magnetic fields in galaxies are passive to dynamics.
Pulsars as excellent probes for the magnetic structure in our Milky Way
JinLin Han
Physics , 2012, DOI: 10.1017/S174392131202371X
Abstract: In this invited talk, I first discuss the advantages and disadvantages of many probes for the magnetic fields of the Milky Way. I conclude that pulsars are the best probes for the magnetic structure in our Galaxy, because magnetic field strength and directions can be derived from their dispersion measures (DMs) and rotation measures (RMs). Using the pulsars as probes, magnetic field structures in the Galactic disk, especially the field reversals between the arms and interarm regions, can be well revealed from the distribution of RM data. The field strengths on large scales and small scales can be derived from RM and DM data. RMs of extragalactic radio sources can be used as the indication of magnetic field directions in the spiral tangential regions, and can be used as probes for the magnetic fields in the regions farther away than pulsars when their median RMs are compared with pulsar RMs.
Hepatitis B Virus (HBV) and Hepatitis C Virus (HCV) Dual Infection
Liu Zhihua,Hou Jinlin
International Journal of Medical Sciences , 2006,
Abstract: Hepatitis B virus (HBV) and hepatitis C virus (HCV) infections account for a substantial proportion of liver diseases worldwide. Because the two hepatotropic viruses share same modes of transmission, coinfection with the two viruses is not uncommon, especially in areas with a high prevalence of HBV infection and among people at high risk for parenteral infection. Patients with dual HBV and HCV infection have more severe liver disease, and are at an increased risk for progression to hepatocellular carcinoma (HCC). Treatment of viral hepatitis due to dual HBV/HCV infection represents a challenge.
On a class of univalent functions
Dinggong Yang,Jinlin Liu
International Journal of Mathematics and Mathematical Sciences , 1999, DOI: 10.1155/s0161171299226051
Abstract: We consider the class of univalent functions defined by the conditions f(z)/z ¢ ‰ 0 and |(z/f(z)) ¢ € 2 ¢ € ¢ € 2| ¢ ‰ ¤ ±,|z|<1, where f(z)=z+ ¢ ˉ is analytic in |z|<1 and 0< ± ¢ ‰ ¤2.
Sequential Tests of Multiple Hypotheses Controlling Type I and II Familywise Error Rates
Jay Bartroff,Jinlin Song
Statistics , 2013,
Abstract: This paper addresses the following general scenario: A scientist wishes to perform a battery of experiments, each generating a sequential stream of data, to investigate some phenomenon. The scientist would like to control the overall error rate in order to draw statistically-valid conclusions from each experiment, while being as efficient as possible. The between-stream data may differ in distribution and dimension but also may be highly correlated, even duplicated exactly in some cases. Treating each experiment as a hypothesis test and adopting the familywise error rate (FWER) metric, we give a procedure that sequentially tests each hypothesis while controlling both the type I and II FWERs regardless of the between-stream correlation, and only requires arbitrary sequential test statistics that control the error rates for a given stream in isolation. The proposed procedure, which we call the sequential Holm procedure because of its inspiration from Holm's (1979) seminal fixed-sample procedure, shows simultaneous savings in expected sample size and less conservative error control relative to fixed sample, sequential Bonferroni, and other recently proposed sequential procedures in a simulation study.
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