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Search Results: 1 - 10 of 22899 matches for " Jing-Houng Kuo "
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The Implementation of Social Welfare Policy in Taiwan: Regarding Single Parent Families
Jing-Houng Kuo,Yung-Yi Tang,Kueiling Chiu
Asian Social Science , 2009, DOI: 10.5539/ass.v5n3p118
Abstract: Within members of the global village, affluent or poor nations alike, the family structure has undergone a dramatic change. Taiwan is no exception. In the past, the traditional Taiwanese family secures social order by fusing social forces adhesively. However, accompanied with economic development, feminist movement and population immigration, the traditional Taiwanese family structure has undergone a dramatically change. The traditional family has faced colossal challenges; the increased unwedded mothers, sky-high divorce rate, separated family due to parents working in the both side of the Taiwan Strait. All of these contribute towards making the single parent family as a “social fact” in the trend of Taiwan social change. Unlike other countries, the ratio of single parent family with male headed families has been relatively high in Taiwan. A 2001 nationwide survey of 3500 single parent families in Taiwan indicates that the ratio of male headed and female headed single parent families respectively is close to 1:1, and the economic condition has no significant difference. Furthermore, since the remarried rate of parents in the single parent family is low (in 2007 the divorce rate in Taiwan was 2.5/1000, the remarried rate for male was 27.1/1000, for female was 11.2/1000), more than half of surveyed single parent families have lived in such structure more than five years. It shows that the lifestyle of single parent family in Taiwan has become commonplace. Two distinctive characteristics of Taiwanese single parent family are the high ratio of (1) covert single parent family due to a conservative culture regarding separation being better than divorce; (2) three generation family with grandparents, single parent, and children becomes the most significant social support network of single parent family. Follow this line of thinking, Taiwanese social policy of single parent family should be planned to adjust to the special cultural needs of single parent families in Taiwan like single parent family living with grandparents. However, Taiwanese government has not yet implemented such policy and establishes various social aids for eliminating poverty. These unstructured aids have focused generally on single parent family with mother only while most single parent families relied on un-official and non-organizational support. This study has suggested that the government should actively construct comprehensive family-focused policy and support network among single parent families to provide services to reduce their heavy housework and work load and explore differe
Insulin resistance is associated with hepatocellular carcinoma in chronic hepatitis C infection
Chao-Hung Hung, Jing-Houng Wang, Tsung-Hui Hu, Chien-Hung Chen, Kuo-Chin Chang, Yi-Hao Yen, Yuan-Hung Kuo, Ming-Chao Tsai, Sheng-Nan Lu, Chuan-Mo Lee
World Journal of Gastroenterology , 2010,
Abstract: AIM: To elucidate the role of insulin resistance (IR) and serum adiponectin level in hepatocellular carcinoma (HCC) associated with chronic hepatitis C.METHODS: Clinical and biochemical characteristics were collected from 165 consecutive patients with newly diagnosed HCC. Homeostasis model assessment of IR (HOMA-IR) and serum adiponectin level were investigated in 188 patients with different stages of hepatitis C virus (HCV) infection.RESULTS: Among HCC patients, type 2 diabetics (DM) was more prevalent in HCV subjects (35.6%, n = 59) compared to hepatitis B virus (HBV; 12.7%, n = 63) or non-HBV, non-HCV cases (7.1%, n = 28). In patients with chronic hepatitis C, HCC subjects had higher blood sugar (P < 0.001), insulin level (P = 0.003) and HOMA-IR (P = 0.018) than those with chronic hepatitis and advanced fibrosis. Age, male sex and body mass index were significantly associated with serum adiponectin level, whereas HOMA-IR was not. Based on stepwise logistic regression analysis, age (OR: 1.124, P < 0.001), serum insulin level (OR: 1.585, P < 0.001), HOMA-IR (OR: 0.495, P = 0.001), DM (OR: 11.601, P = 0.002) and male sex (OR: 3.877, P = 0.016) were independently associated with HCC. This result was similar even if the diabetic subjects were excluded for analysis.CONCLUSION: Insulin resistance measured by HOMA-IR, regardless of the presence of diabetes, is significantly associated with HCC development in patients with chronic HCV infection.
The Changes of Liver Stiffness and Its Associated Factors for Chronic Hepatitis B Patients with Entecavir Therapy
Yuan-Hung Kuo, Sheng-Nan Lu, Chien-Hung Chen, Kuo-Chin Chang, Chao-Hung Hung, Wei-Chen Tai, Ming-Chao Tsai, Po-Lin Tseng, Tsung-Hui Hu, Jing-Houng Wang
PLOS ONE , 2014, DOI: 10.1371/journal.pone.0093160
Abstract: Liver stiffness measurement (LSM) using transient elastography has been proposed to assess liver fibrosis well in various liver diseases. This study was to determine the changes of LSM and its associated factors for chronic hepatitis B (CHB) patients undergoing Entecavir therapy. Consecutive CHB patients underwent Entecavir therapy with two LSMs were enrolled. Patients with aspartate transaminase (AST) and/or alanine transaminase ≧200 IU/L were excluded. The retrospective study enrolled 233 patients including 132 without cirrhosis (group 1) and 101 with cirrhosis (group 2). The mean values of initial liver stiffness were 7.9 and 16.6 kPa for patients in group 1 and group 2, respectively (p<0.001). In addition to the decline of transaminase levels, there was significant reduction of liver stiffness value in a mean interval of 52.8 and 61.9 weeks between the two LSMs for patients in group 1 and 2, respectively (p<0.001). Multivariate analysis showed that higher initial LSM value and presence of hepatitis B e-antigen were associated with a greater decline of LSM value, whereas follow-up AST≧40 IU/L with increased LSM value for group 1 patients. For group 2 patients, longer interval between the two LSMs, higher initial LSM value and AST≧40 IU/L were associated with a greater decline of LSM value, whereas presence of diabetes mellitus (DM) contributed to increased LSM value. In conclusion, CHB patients improved their LSM values after Entecavir therapy. Higher initial LSM value contributed to greater LSM reduction. However, in cirrhotic patients, DM was associated with an increased LSM value after therapy.
Chronic Hepatitis C Virus Infection Associated with Dermatomyositis and Hepatocellular Carcinoma.
Kwong-Ming Kee,Jing-Houng Wang,Chuan-Mo Lee,Chi-Sin Changchien
Chang Gung Medical Journal , 2004,
Abstract: Dermatomyositis is a rare and idiopathic inflammatory myopathy with characteristiccutaneous manifestations. In recent years, some researchers have showed the cause of dermatomyositismight be due to an autoimmune response induced by viral infections.However, chronic hepatitis C virus (HCV) infection associated with dermatomyositis is veryrare. In this report, we present a patient with dematomyositis with abnormal liver functiontest results and elevated alfa-fetoprotein level. After excluding multiple viral infectionsknown to cause myositis, the case was proven to be chronic hepatitis C by positive HCVRNAin the serum. Abdominal computed tomography showed a liver tumor on the right lobeand needle biopsy proved it to be hepatocellular carcinoma. Chronic hepatitis C or hepatocellularcarcinoma might cause dermatomyositis by inducing the formation of autoantibodies.Chronic hepatitis C or hepatocellular carcinoma should be considered in patients of dermatomyositisif no other cause is found.
Hepatitis Delta Virus and GBV-C Infection in Two Neighboring Hepatitis B Virus and Hepatitis C Virus – Endemic Villages in Taiwan
Chang-Jung Chang,Jui-Chin Chiang,Sheng-Nan Lu,Jing-Houng Wang
Chang Gung Medical Journal , 2010,
Abstract: Background: Previous reports in Taiwan have shown that the hepatitis B virus (HBV)- andhepatitis C virus (HCV)-endemic areas are also endemic for hepatitis D virus(HDV), GBV-C and TT virus. This study aimed to elucidate the epidemiologyof HDV and GBV-C infection in two neighboring HBV- and HCVendemicvillages, to deduce the epidemiological characteristics of multipleviral infections in communities.Methods: A total of 74 adult residents of Wukwai (W) village and 95 adults residentsof Haipu (H) village were studied. Laboratory tests for all subjects includedalanine transaminase (ALT), hepatitis B surface antigen (HBsAg), anti-HCV,HCV RNA, genotype of HCV, GBV-C RNA, and anti-GBV-C E2. Anti-HDV was checked only in HBsAg-positive subjects.Results: Subjects from W village were older than those from H village (61.7
The Outcome of Prophylactic Intravenous Cefazolin and Ceftriaxone in Cirrhotic Patients at Different Clinical Stages of Disease after Endoscopic Interventions for Acute Variceal Hemorrhage
Cheng-Kun Wu, Jing-Houng Wang, Chen-Hsiang Lee, Keng-Liang Wu, Wei-Chen Tai, Sheng-Nan Lu, Tsung-Hui Hu, Seng-Kee Chuah
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0061666
Abstract: Antibiotic prophylaxis with norfloxacin, intravenous ciprofloxacin, or ceftriaxone has been recommended for cirrhotic patients with gastrointestinal hemorrhage but little is known about intravenous cefazolin. This study aimed to compare the outcome of intravenous cefazolin and ceftriaxone as prophylactic antibiotics among cirrhotic patients at different clinical stages, and to identify the associated risk factors. The medical records of 713 patients with acute variceal bleeding who had received endoscopic procedures from were reviewed. Three hundred and eleven patients were entered for age-matched adjustment after strict exclusion criteria. After the adjustment, a total of 102 patients were enrolled and sorted into 2 groups according to the severity of cirrhosis: group A (Child’s A patients, n = 51) and group B (Child’s B and C patients, n = 51). The outcomes were prevention of infection, time of rebleeding, and death. Our subgroup analysis results failed to show a significant difference in infection prevention between patients who received prophylactic cefazolin and those who received ceftriaxone among Child’s A patients (93.1% vs. 90.9%, p = 0.641); however, a trend of significance in favor of ceftriaxone prophylaxis (77.8% vs. 87.5%, p = 0.072) was seen among Child’s B and C patients. More rebleeding cases were observed in patients who received cefazolin than in those who received ceftriaxone among Child’s B and C patients (66.7% vs. 25.0%, p = 0.011) but not in Child’s A patients (32% vs. 40.9%, p = 0.376). The risk factors associated with rebleeding were history of bleeding and use of prophylactic cefazolin among Child’s B and C patients. In conclusion, this study suggests that prophylactic intravenous cefazolin may not be inferior to ceftriaxone in preventing infections and reducing rebleeding among Child’s A cirrhotic patients after endoscopic interventions for acute variceal bleeding. Prophylactic intravenous ceftriaxone yields better outcome among Child’s B and C patients.
The Influential Roles of Antibiotics Prophylaxis in Cirrhotic Patients with Peptic Ulcer Bleeding after Initial Endoscopic Treatments
Shih-Cheng Yang, Jen-Chieh Chen, Wei-Chen Tai, Cheng-Kun Wu, Chen-Hsiang Lee, Keng-Liang Wu, Yi-Chun Chiu, Jing-Houng Wang, Sheng-Nan Lu, Seng-Kee Chuah
PLOS ONE , 2014, DOI: 10.1371/journal.pone.0096394
Abstract: The influential roles of antibiotic prophylaxis on cirrhotic patients with peptic ulcer bleeding are still not well documented. The purpose of this study is to clarify these influential roles and to identify the risk factors associated with rebleeding, bacterial infection and in-hospital mortality. A cross-sectional, chart review study was conducted on 210 cirrhotic patients with acute peptic ulcer hemorrhage who underwent therapeutic endoscopic procedures. Patients were divided into group A (with prophylactic intravenous ceftriaxone, n = 74) and group B (without antibiotics, n = 136). The outcomes were length of hospital days, prevention of infection, rebleeding rate and in-hospital mortality. Our results showed that more patients suffered from rebleeding and infection in group B than group A (31.6% vs. 5.4%; p<0.001 and 25% vs. 10.8%; p = 0.014 respectively). The risk factors for rebleeding were active alcoholism, unit of blood transfusion, Rockall score, model for end-stage liver disease score and antibiotic prophylaxis. The risk factors for infection were active alcoholism, Child-Pugh C, Rockall score and antibiotic prophylaxis. Rockall score was the predictive factor for in-hospital mortality. In conclusions, antibiotic prophylaxis in cirrhotic patients after endoscopic interventions for acute peptic ulcer hemorrhage reduced infections and rebleeding rate but not in-hospital mortality. Rockall score was the predictive factor of in-hospital mortality.
Long-Term Effect of Interferon Plus Ribavirin on Hepatitis B Surface Antigen Seroclearance in Patients Dually Infected with Hepatitis B and C Viruses
Ming-Lun Yeh,Chao-Hung Hung,Jee-Fu Huang,Chun-Jen Liu,Chuan-Mo Lee,Chia-Yen Dai,Jing-Houng Wang,Zu-Yau Lin,Sheng-Nan Lu,Tsung-Hui Hu,Ming-Lung Yu,Jia-Horng Kao,Wan-Long Chuang,Pei-Jer Chen,Ding-Shinn Chen
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0020752
Abstract: Interferon-α/ribavirin combination therapy might promote hepatitis B surface antigen (HBsAg) seroclearance in patients dually infected with hepatitis B and C viruses (HBV/HCV), but the long-term effect remains unclear. We aimed to investigate the rate of and the factors associated with HBsAg seroclearance during long-term follow-up after interferon-α/ribavirin combination therapy in HBV/HCV dually-infected patients.
Simultaneous Switching Noise Mitigation Capability with Low Parasitic Effect Using Aperiodic High-Impedance Surface Structure
Chin-Sheng Chang;Mau-Phon Houng;Ding-Bing Lin;Kuo-Chiang Hung;I-Tseng Tang
PIER Letters , 2008, DOI: 10.2528/PIERL08082902
Abstract: A novel design with low parasitic effect for eliminating the simultaneous switching noise (SSN) in high-speed circuits is proposed by using the aperiodic high-impedance surface (A-HIS) structure. The A-HIS configuration is proposed in this work, revealing suppression of the SSN from 1.1~1.85 GHz. It is shown that the HIS structure with aperiodic design, the SSN will be effectively suppressed. The undesired resonances of the proposed A-HIS structure are less than that of the conventional structure below 1 GHz. Less undesired peaks will ensure the electromagnetic interference (EMI) and signal integrity (SI). The measured results show very well compared with the conventional periodical HIS structures. The suppression results of the proposed A-HIS structure is checked by both measurement and simulation results. By using this proposed method, the simplicity of the structure is easier to fabricate as well as to route signal lines with a perfect power/ground planes. In addition, the proposed designs provide excellent SSN suppression and good signal integrity (SI) as the conventional structure.
Analysis and Suppression on Simultaneous Switching Noise Coupling Between Multi-Cavities for Multilayer Pcbs
Chin-Sheng Chang;Mau-Phon Houng;Ding-Bing Lin;Kuo-Chiang Hung;Ray-Fong Hong
PIER Letters , 2008, DOI: 10.2528/PIERL08112501
Abstract: In this letter, an easy concept to eliminate the simultaneous switching noise (SSN) in multilayer board is proposed. Use of the low impedance element provides a short path to lead noise to ground, called virtual shield. This method could effectively suppress the first mode of the parallel resonance, and the wider-band suppression could be obtained by array short via. It is also proved that the virtual shield concept has to be placed as the excited source at the same layer.
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