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Search Results: 1 - 10 of 29213 matches for " Jing Pan "
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Experimental study on role of cannabinoid receptor 1 in non-alcoholic fatty liver disease among rats
PAN Jing
Journal of Clinical Hepatology , 2013,
Abstract: ObjectiveTo observe the expression of endogenous cannabinoid receptor l (CB1) in rats with non-alcoholic fatty liver disease (NAFLD) and to preliminarily investigate the role of CB1 receptors in the pathogenesis of NAFLD. MethodsForty-eight male SD rats were randomly divided into three groups: control group (receiving normal feed), model group (receiving high-sugar and high-fat feed), and rimonabant group (receiving high-sugar and high-fat feed and rimonabant). At the end of the 4th or 8th week of experiment, 8 of each group were sacrificed. The body weight was measured, and the liver index was calculated. The serum levels of alanine aminotransferase (ALT), aspartate aminotransferase (AST), triglyceride (TG), and total cholesterol (TC) were determined. The serum levels of leptin and tumor necrosis factor (TNF)α were determined by ELISA. The liver tissue was treated by HE staining, and the pathological changes were observed. Immunohistochemical staining was used to evaluate the CB1 receptor expression in liver tissues in different stages of NAFLD. One-way analysis of variance and t-test were used for within-group and between-group comparisons. Pearson′s linear-correlation analysis was used for evaluating the correlation between indices. ResultsThe model group had significantly higher serum levels of ALT, AST, TC, TG, leptin, and TNF-α than the control group and rimonabant group (P<0.05). The model group showed simple fatty degeneration of the liver after 4 weeks and diffuse fatty degeneration of the liver with inflammatory cell infiltration after 8 weeks, while the rimonabant group had less severe liver lesions at the same time. CB1 receptor expression was not detected in the control group, but was detected in the model group and rimonabant group, according to the immunohistochemical staining, and the model group had a significantly higher integral optical density than the rimonabant group (P<0.05). ConclusionThe expression of CB1 receptors is enhanced in patients with NAFLD, and it may act together with TNF-α and leptin to promote the progression of NAFLD.
An Algorithm for Medical Imagining Compression That Is Oriented to ROI-Characteristics Protection  [PDF]
Renjun Shuai, Yang Shen, Jing Pan
Journal of Applied Mathematics and Physics (JAMP) , 2015, DOI: 10.4236/jamp.2015.37106
Abstract: In order to protect the ROI (region of interest) characteristics while greatly improving medical imaging compression ratio, we are proposing an algorithm for medical imagining compression that is oriented to ROI-characteristics protection. Firstly, an improved ROI segmentation algorithm is put forward based on the analysis of the ROI segmentation. Then, after the ROI segmented, the ROI edge is extracted and encoded with Freeman chain coding. Finally, the ROI is compressed by lossless compression with shearlet; the ROB (region of background) is compressed by the method of high ratio lossy compression combining with Wavelet and Fractal. Simulation results show that the ROI is segmented precisely. It holds edge integrity and has high quality reconstruction processed by the presented method, helping protect ROI characteristics while greatly improving the compression ratio.
Concentration Wave for a Class of Reaction Chromatography System with Pulse Injections  [PDF]
Jing Zhang, Maofei Shao, Tao Pan
American Journal of Computational Mathematics (AJCM) , 2016, DOI: 10.4236/ajcm.2016.63023
Abstract: By using fluid dynamics theory with the effects of adsorption and reaction, the chromatography model with a reaction AB was established as a system of two hyperbolic partial differential equations (PDE’s). In some practical situations, the reaction chromatography model was simplified a semi-coupled system of two linear hyperbolic PDE’s. In which, the reactant concentration wave model was the initial-boundary value problem of a self-closed hyperbolic PDE, while the resultant concentration wave model was the initial-boundary value problem of hyperbolic PDE coupling reactant concentration. The general explicit expressions for the concentration wave of the reactants and resultants were derived by Laplace transform. The δ-pulse and wide pulse injections were taken as the examples to discuss detailedly, and then the stability analysis between the resultant solutions of the two modes of pulse injection was further discussed. It was significant for further analysis of chromatography, optimizing chromatographic separation, determining the physical and chemical characters.
Global Optimization of Norris Derivative Filtering with Application for Near-Infrared Analysis of Serum Urea Nitrogen  [PDF]
Yihui Yang, Tao Pan, Jing Zhang
American Journal of Analytical Chemistry (AJAC) , 2019, DOI: 10.4236/ajac.2019.105013
Abstract: Near-infrared (NIR) spectroscopy combined with chemometrics methods was applied to the rapid and reagent-free analysis of serum urea nitrogen (SUN). The mul-partitions modeling was performed to achieve parameter stability. A large-scale parameter cyclic and global optimization platform for Norris derivative filter (NDF) of three parameters (the derivative order: d, the number of smoothing points: s and the number of differential gaps: g) was developed with PLS regression. Meantime, the parameters’ adaptive analysis of NDF algorithm was also given, and achieved a significantly better modeling effect than one without spectral pre-processing. After eliminating the interference wavebands of saturated absorption, the modeling performance was further improved. In validation, the root mean square error (SEP), correlation coefficient (RP) for prediction and the ratio of performance to deviation (RPD) were 1.66 mmol?L-1, 0.966 and 4.7, respectively. The results showed that the high-precision analysis of SUN was feasibility based on NIR spectroscopy and Norris-PLS. The global optimization method of NDF is also expected to be applied to other analysis objects.
Rapid Analysis of Soil Copper Content for the Pearl River Delta Based on Near-Infrared Spectroscopy Combined with SG-PLS  [PDF]
Guangwei Li, Jing Zhang, Tao Pan, Jing Yu, Lijun Yao
American Journal of Analytical Chemistry (AJAC) , 2018, DOI: 10.4236/ajac.2018.912045
Abstract: Using near-infrared (NIR) spectroscopy combined with an optimal method for Savitzky-Golay (SG) smoothing and partial least squares (PLS) regression, a rapid analysis method was established for copper content in the beach reclamation soil samples from Pearl River Delta in China. A framework with calibration, prediction and validation was established by considering randomness and stability. The parameters were optimized according to the comprehensive index (SEP+) to produce modeling stability. The validation results show that, based on the SG-PLS model in long-NIR region (1100 - 2498 nm) with first-order derivative, fifth degree polynomial, seven smoothing points and six PLS factors, the corresponding root mean square error (SEP), correlation coefficient of prediction (RP) and average relative error (ARE) were 0.31 mg·kg-1, 0.924 and 4.5%, respectively. The result indicates high prediction accuracy. The relevant parameter selection can also provide a reference for designing small and dedicated spectrometer.
Molecular Cartography: Mapping the Landscape of Meiotic Recombination
Jing Pan,Scott Keeney
PLOS Biology , 2012, DOI: 10.1371/journal.pbio.0050333
Abstract:
Molecular Cartography: Mapping the Landscape of Meiotic Recombination
Jing Pan,Scott Keeney
PLOS Biology , 2007, DOI: 10.1371/journal.pbio.0050333
Abstract:
Asymptotic tails of massive scalar fields in a stationary axisymmetric EMDA black hole geometry
Qiyuan Pan,Jiliang Jing
Physics , 2004, DOI: 10.1088/0256-307X/21/10/002
Abstract: The late-time tail behavior of massive scalar fields is studied analytically in a stationary axisymmetric EMDA black hole geometry. It is shown that the asymptotic behavior of massive perturbations is dominated by the oscillatory inverse power-law decaying tail $ t^{-(l+3/2)}\sin(\mu t)$ at the intermediate late times, and by the asymptotic tail $ t^{-5/6}\sin(\mu t)$ at asymptotically late times. Our result seems to suggest that the intermediate tails $ t^{-(l+3/2)}\sin(\mu t)$ and the asymptotically tails $t^{-5/6} \sin(\mu t)$ may be quite general features for evolution of massive scalar fields in any four dimensional asymptotically flat rotating black hole backgrounds.
Hawking radiation, Entanglement and Teleportation in background of an asymptotically flat static black hole
Qiyuan Pan,Jiliang Jing
Physics , 2008, DOI: 10.1103/PhysRevD.78.065015
Abstract: The effect of the Hawking temperature on the entanglement and teleportation for the scalar field in a most general, static and asymptotically flat black hole with spherical symmetry has been investigated. It is shown that the same "initial entanglement" for the state parameter $\alpha$ and its "normalized partners" $\sqrt{1-\alpha^{2}}$ will be degraded by the Hawking effect with increasing Hawking temperature along two different trajectories except for the maximally entangled state. In the infinite Hawking temperature limit, corresponding to the case of the black hole evaporating completely, the state has no longer distillable entanglement for any $\alpha$. It is interesting to note that the mutual information in this limit equals to just half of the "initially mutual information". It has also been demonstrated that the fidelity of teleportation decreases as the Hawking temperature increases, which just indicates the degradation of entanglement.
Evolution of arbitrary spin fields in the Schwarzschild-monopole spacetime
Qiyuan Pan,Jiliang Jing
Physics , 2008, DOI: 10.1088/0264-9381/25/3/038002
Abstract: The quasinormal modes (QNMs) and the late-time behavior of arbitrary spin fields are studied in the background of a Schwarzschild black hole with a global monopole (SBHGM). It has been shown that the real part of the QNMs for a SBHGM decreases as the symmetry breaking scale parameter $H$ increases but imaginary part increases instead. For large overtone number $n$, these QNMs become evenly spaced and the spacing for the imaginary part equals to $-i(1-H)^{3/2}/(4M)$ which is dependent of $H$ but independent of the quantum number $l$. It is surprisingly found that the late-time behavior is dominated by an inverse power-law tail $t^{-2[1+\sqrt{(s+1/2)^{2}+ (l-s)(l+s+1)/(1-H)}]}$ for each $l$, and as $H\to0$ it reduces to the Schwarzschild case $t^{-(2l+3)}$ which is independent of the spin number $s$.
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