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Search Results: 1 - 10 of 106327 matches for " Jing Jing Hong Ying Jiang Yuanyuan Gao Xiaofeng "
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Study on Web Retrieval Query Fusion Based on Relevance Feedback
基于相关反馈的Web检索提问融合研究

Jing Jing Hong Ying Jiang Yuanyuan Gao Xiaofeng,
景璟
,洪颖,蒋媛媛,杲晓锋

现代图书情报技术 , 2011,
Abstract: This paper introduces the combination of query fusion and relevance feedback methods.By analyzing previous TopN documents selection strategy, it puts forward a query fusion algorithm using correlation coefficient to select a variable number of TopN documents in order to extend query, which is called variable TopN feedback-based query fusion algorithm. Fixed and variable TopN query fusion experiments are analyzed separately, and the test results show that the variable TopN feedback method improves the retrieval performance to some extent.
Enzymatic Synthesis of Ethyl Oleate by Lipase in AOT Reverse Micellar System
AOT逆胶束体系脂肪酶催化合成油酸乙酯

LI Wei-jie,GAO Jing,JIANG Yan-jun,HUANG Zhi-hong,HE Ying,ZHOU Li-ya,
李伟杰
,高静,姜艳军,黄志红,贺莹,周丽亚

过程工程学报 , 2008,
Abstract: 在二-(2-乙基己基)琥珀酸酯磺酸钠和异辛烷构建的逆胶束体系中,以Lipex脂肪酶为催化剂,合成了油酸乙酯,考察了各影响因素对其产率的影响,并进行了脂肪酶紫外荧光检测和体系粒度分析.结果表明,Lipex脂肪酶具有良好的催化活性,反应条件优化选用异辛烷为溶剂,在反应温度25℃、缓冲液pH 6.5、水/表面活性剂(摩尔比)10、乙醇/油酸(摩尔比)20及Lipex脂肪酶浓度0.035 g/L、油酸浓度0.005 mol/L、摇床转速150 r/min、反应36 h的条件下,油酸乙酯产率达到71.25%.逆胶束粒度和酶构象直接影响酶活性,最适逆胶柬粒度约为80 nm.
A New Dynamic Self-Organizing Method for Mobile Robot Environment Mapping  [PDF]
Xiaogang Ruan, Yuanyuan Gao, Hongjun Song, Jing Chen
Journal of Intelligent Learning Systems and Applications (JILSA) , 2011, DOI: 10.4236/jilsa.2011.34028
Abstract: To solve the mapping problem for the mobile robots in the unknown environment, a dynamic growing self-organizing map with growing-threshold tuning automatically algorithm (DGSOMGT) based on Self-organizing Map is proposed. It introduces a value of spread factor to describe the changing process of the growing threshold dynamically. The method realizes the network structure growing by training through mobile robot movement constantly in the unknown environment. The proposed algorithm is based on self-organizing map and can adjust the growing-threshold value by the number of network neurons increasing. It avoids tuning the parameters repeatedly by human. The experimental results show that the proposed method detects the complex environment quickly, effectively and correctly. The robot can realize environment mapping automatically. Compared with the other methods the proposed mapping strategy has better topological properties and time property.
Childhood Sexual Abuse and the Development of Recurrent Major Depression in Chinese Women
Jing Chen, Yiyun Cai, Enzhao Cong, Ying Liu, Jingfang Gao, Youhui Li, Ming Tao, Kerang Zhang, Xumei Wang, Chengge Gao, Lijun Yang, Kan Li, Jianguo Shi, Gang Wang, Lanfen Liu, Jinbei Zhang, Bo Du, Guoqing Jiang, Jianhua Shen, Zhen Zhang, Wei Liang, Jing Sun, Jian Hu, Tiebang Liu, Xueyi Wang, Guodong Miao, Huaqing Meng, Yi Li, Chunmei Hu, Yi Li, Guoping Huang, Gongying Li, Baowei Ha, Hong Deng, Qiyi Mei, Hui Zhong, Shugui Gao, Hong Sang, Yutang Zhang, Xiang Fang, Fengyu Yu, Donglin Yang, Tieqiao Liu, Yunchun Chen, Xiaohong Hong, Wenyuan Wu, Guibing Chen, Min Cai, Yan Song, Jiyang Pan, Jicheng Dong, Runde Pan, Wei Zhang, Zhenming Shen, Zhengrong Liu, Danhua Gu, Xiaoping Wang, Xiaojuan Liu, Qiwen Zhang, Yihan Li, Yiping Chen, Kenneth S. Kendler, Shenxun Shi, Jonathan Flint
PLOS ONE , 2014, DOI: 10.1371/journal.pone.0087569
Abstract: Background Our prior study in Han Chinese women has shown that women with a history of childhood sexual abuse (CSA) are at increased risk for developing major depression (MD). Would this relationship be found in our whole data set? Method Three levels of CSA (non-genital, genital, and intercourse) were assessed by self-report in two groups of Han Chinese women: 6017 clinically ascertained with recurrent MD and 5983 matched controls. Diagnostic and other risk factor information was assessed at personal interview. Odds ratios (ORs) were calculated by logistic regression. Results We confirmed earlier results by replicating prior analyses in 3,950 new recurrent MD cases. There were no significant differences between the two data sets. Any form of CSA was significantly associated with recurrent MD (OR 4.06, 95% confidence interval (CI) [3.19–5.24]). This association strengthened with increasing CSA severity: non-genital (OR 2.21, 95% CI 1.58–3.15), genital (OR 5.24, 95% CI 3.52–8.15) and intercourse (OR 10.65, 95% CI 5.56–23.71). Among the depressed women, those with CSA had an earlier age of onset, longer depressive episodes. Recurrent MD patients those with CSA had an increased risk for dysthymia (OR 1.60, 95%CI 1.11–2.27) and phobia (OR 1.41, 95%CI 1.09–1.80). Any form of CSA was significantly associated with suicidal ideation or attempt (OR 1.50, 95% CI 1.20–1.89) and feelings of worthlessness or guilt (OR 1.41, 95% CI 1.02–2.02). Intercourse (OR 3.47, 95%CI 1.66–8.22), use of force and threats (OR 1.95, 95%CI 1.05–3.82) and how strongly the victims were affected at the time (OR 1.39, 95%CI 1.20–1.64) were significantly associated with recurrent MD. Conclusions In Chinese women CSA is strongly associated with recurrent MD and this association increases with greater severity of CSA. Depressed women with CSA have some specific clinical traits. Some features of CSA were associated with greater likelihood of developing recurrent MD.
Quantitative Analysis of Burden of Infectious Diarrhea Associated with Floods in Northwest of Anhui Province, China: A Mixed Method Evaluation
Guoyong Ding, Ying Zhang, Lu Gao, Wei Ma, Xiujun Li, Jing Liu, Qiyong Liu, Baofa Jiang
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0065112
Abstract: Background Persistent and heavy rainfall in the upper and middle Huaihe River of China brought about severe floods during the end of June and July 2007. However, there has been no assessment on the association between the floods and infectious diarrhea. This study aimed to quantify the impact of the floods in 2007 on the burden of disease due to infectious diarrhea in northwest of Anhui Province. Methods A time-stratified case-crossover analysis was firstly conducted to examine the relationship between daily cases of infectious diarrhea and the 2007 floods in Fuyang and Bozhou of Anhui Province. Odds ratios (ORs) of the flood risk were quantified by conditional logistic regression. The years lived with disability (YLDs) of infectious diarrhea attributable to floods were then estimated based on the WHO framework of the calculating potential impact fraction in the Burden of Disease study. Results A total of 197 infectious diarrheas were notified during the exposure and control periods in the two study areas. The strongest effect was shown with a 2-day lag in Fuyang and a 5-day lag in Bozhou. Multivariable analysis showed that floods were significantly associated with an increased risk of the number cases of infectious diarrhea (OR = 3.175, 95%CI: 1.126–8.954 in Fuyang; OR = 6.754, 95%CI: 1.954–23.344 in Bozhou). Attributable YLD per 1000 of infectious diarrhea resulting from the floods was 0.0081 in Fuyang and 0.0209 in Bozhou. Conclusions Our findings confirm that floods have significantly increased the risks of infectious diarrhea in the study areas. In addition, prolonged moderate flood may cause more burdens of infectious diarrheas than severe flood with a shorter duration. More attention should be paid to particular vulnerable groups, including younger children and elderly, in developing public health preparation and intervention programs. Findings have significant implications for developing strategies to prevent and reduce health impact of floods.
An Appraisal of Anatomical and Limited Hepatectomy for Regional Hepatolithiasis
Hui Jiang,Hong Wu,Ying-long Xu,Jing-zhou Wang,Yong Zeng
HPB Surgery , 2010, DOI: 10.1155/2010/791625
Abstract: Aim. Determination of first line treatment with limited hepatectomy or Anatomical hepatectomy provides better clinical outcome. Methods. Immediate and long-term outcomes of 106 patients who underwent partial hepatectomy for RH at our institution from January 2001 to February 2005 were analyzed retrospectively. Clinical end-points included time to recovery of hepatic function, residual stones, infection of the liver remnant, bile leakage, recurrent stones, morbidity, and mortality. Results. LH was performed in 59 patients and AH in 47 patients as first-line treatment. The time of hepatic function recovery was not statistically different between the two groups ( ). However, Patients in AH group suffered from less residual stones ( ), less infection of the raw surface of liver remnant ( ), and less bile leakage ( ), with a median follow-up of months (range 3–48), and AH group suffered a less recurrent stone rate ( ). No difference in morbidity, and mortality rates between the two groups. Conclusion. AH is a safe and effective treatment for RH, with a fair rate of surgical complications, it should be considered as first-line treatment of RH. 1. Introduction Hepatolithiasis, which is defined as the occurrence of stones in any intrahepatic bile duct proximal to the confluence of the right and left hepatic ducts, is prevalent disease in Southeast Asia and is especially prevalent in China [1, 2]. Su et al. [3] reported that the relative incidence to be 20% of all cases of gallstone disease. Huang ZQ reported hepatolithiasis is now become to be mild symptoms, regional types, and early disease courses [4]. To prevent immediate and late sequelae of hepatolithiasis, such as suppurative cholangitis, septicemia, secondary biliary cirrhosis with resultant portal hypertension, bleeding varices, and hepatic failure [5], aggressive treatment is needed. Surgeons have persistently explored for its treatment, from bile duct exploration to liver parenchyma incision, cholangioscopic lithotomy, and liver resection; all are for one single purpose: “to remove lesions, extract up stone, correct stricture, keep drainage thoroughly, and prevent recurrence”. Hepatectomy seems to be the most definitive approach for hepatolithiasis, because it can remove the stones and the biliary stricture simultaneously, thus reducing the risk of recurrent stones [6–9]. Hepatectomy offers the optimal treatment for this disease in selected patients [8–11]. Unfortunately, immediate and long clinical outcomes after partial hepatectomy is still unsatisfactory because of the high incidence of
Gene Silencing of Toll-Like Receptor 2 Inhibits Proliferation of Human Liver Cancer Cells and Secretion of Inflammatory Cytokines
Yuzheng Huang, Bing Cai, Ming Xu, Zhiqin Qiu, Yonghui Tao, Ying Zhang, Jie Wang, Yongliang Xu, Yonghua Zhou, Jing Yang, Xiaofeng Han, Qi Gao
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0038890
Abstract: Background Toll-like receptors (TLRs) are key factors in the innate immune system and initiate the inflammatory response to foreign pathogens such as bacteria, fungi and viruses. In the microenvironment of tumorigenesis, TLRs can promote inflammation and cell survival. Toll-like receptor 2/6 (TLR2/6) signaling in tumor cells is regarded as one of the mechanisms of chronic inflammation but it can also mediate tumor cell immune escape and tumor progression. However, the expression of TLR2 and its biological function in the development and progression of hepatocarcinoma have not been investigated. This study aimed to determine the expression of TLRs 1–10 in the established human hepatocellular carcinoma cell line BLE-7402, to investigate the biological effect of TLR2 on cell growth and survival. Methods TLR expression in BLE-7402 cells was assayed by RT-PCR, real-time PCR and flow cytometry (FCM). To further investigate the function of TLR2 in hepatocarcinoma growth, BLE-7402 cells were transfected with recombinant plasmids expressing one of three forms of TLR2 siRNA (sh-TLR2 RNAi(A, B and C)). TLR2 knockdown was confirmed using RT-PCR, real-time PCR and fluorescence microscopy. Tumor cell proliferation was monitored by MTT assay and secreted cytokines in the supernatant of transfected cells were measured by bead-based FCM, the function of TLR2 siRNA was also investigated in vivo. Results The BLE-7402 cell line expressed TLRs 2 to 10 at both mRNA and protein levels. TLR2 was the most highly expressed TLR. While all the three siRNAs inhibited TLR2 mRNA and protein expression, sh-TLR2 RNAi(B) had the strongest knockdown effect. TLR2 knockdown with sh-TLR2 RNAi(B) reduced cell proliferation. Furthermore, secretion of IL-6 and IL-8 was also reduced. The result showed a drastic reduction in tumor volume in mice treated with sh-TLR2 RNAi(B). Discussion These results suggest that TLR2 knockdown inhibit proliferation of cultured hepatocarcinoma cells and decrease the secretion of cytokines. It is suggested that TLR2 silencing may worth further investigations for siRNA based gene therapy in treatment of hepatocarcinoma.
Suicidal Risk Factors of Recurrent Major Depression in Han Chinese Women
Yuzhang Zhu, Hongni Zhang, Shenxun Shi, Jingfang Gao, Youhui Li, Ming Tao, Kerang Zhang, Xumei Wang, Chengge Gao, Lijun Yang, Kan Li, Jianguo Shi, Gang Wang, Lanfen Liu, Jinbei Zhang, Bo Du, Guoqing Jiang, Jianhua Shen, Zhen Zhang, Wei Liang, Jing Sun, Jian Hu, Tiebang Liu, Xueyi Wang, Guodong Miao, Huaqing Meng, Yi Li, Chunmei Hu, Yi Li, Guoping Huang, Gongying Li, Baowei Ha, Hong Deng, Qiyi Mei, Hui Zhong, Shugui Gao, Hong Sang, Yutang Zhang, Xiang Fang, Fengyu Yu, Donglin Yang, Tieqiao Liu, Yunchun Chen, Xiaohong Hong, Wenyuan Wu, Guibing Chen, Min Cai, Yan Song, Jiyang Pan, Jicheng Dong, Runde Pan, Wei Zhang, Zhenming Shen, Zhengrong Liu, Danhua Gu, Xiaoping Wang, Xiaojuan Liu, Qiwen Zhang, Yihan Li, Yiping Chen, Kenneth Seedman Kendler, Jonathan Flint, Ying Liu
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0080030
Abstract: The relationship between suicidality and major depression is complex. Socio- demography, clinical features, comorbidity, clinical symptoms, and stressful life events are important factors influencing suicide in major depression, but these are not well defined. Thus, the aim of the present study was to assess the associations between the above-mentioned factors and suicide ideation, suicide plan, and suicide attempt in 6008 Han Chinese women with recurrent major depression (MD). Patients with any suicidality had significantly more MD symptoms, a significantly greater number of stressful life events, a positive family history of MD, a greater number of episodes, a significant experience of melancholia, and earlier age of onset. Comorbidity with dysthymia, generalized anxiety disorder (GAD), social phobia, and animal phobia was seen in suicidal patients. The present findings indicate that specific factors act to increase the likelihood of suicide in MD. Our results may help improve the clinical assessment of suicide risk in depressed patients, especially for women.
Clinical Features of Patients with Dysthymia in a Large Cohort of Han Chinese Women with Recurrent Major Depression
Wenqing Wu, Zhoubing Wang, Yan Wei, Guanghua Zhang, Shenxun Shi, Jingfang Gao, Youhui Li, Ming Tao, Kerang Zhang, Xumei Wang, Chengge Gao, Lijun Yang, Kan Li, Jianguo Shi, Gang Wang, Lanfen Liu, Jinbei Zhang, Bo Du, Guoqing Jiang, Jianhua Shen, Ying Liu, Wei Liang, Jing Sun, Jian Hu, Tiebang Liu, Xueyi Wang, Guodong Miao, Huaqing Meng, Yi Li, Chunmei Hu, Yi Li, Guoping Huang, Gongying Li, Baowei Ha, Hong Deng, Qiyi Mei, Hui Zhong, Shugui Gao, Hong Sang, Yutang Zhang, Xiang Fang, Fengyu Yu, Donglin Yang, Tieqiao Liu, Yunchun Chen, Xiaohong Hong, Wenyuan Wu, Guibing Chen, Min Cai, Yan Song, Jiyang Pan, Jicheng Dong, Runde Pan, Wei Zhang, Zhenming Shen, Zhengrong Liu, Danhua Gu, Xiaoping Wang, Xiaojuan Liu, Qiwen Zhang, Yihan Li, Yiping Chen, Kenneth S. Kendler, Jonathan Flint, Zhen Zhang
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0083490
Abstract: Background Dysthymia is a form of chronic mild depression that has a complex relationship with major depressive disorder (MDD). Here we investigate the role of environmental risk factors, including stressful life events and parenting style, in patients with both MDD and dysthymia. We ask whether these risk factors act in the same way in MDD with and without dysthymia. Results We examined the clinical features in 5,950 Han Chinese women with MDD between 30–60 years of age across China. We confirmed earlier results by replicating prior analyses in 3,950 new MDD cases. There were no significant differences between the two data sets. We identified sixteen stressful life events that significantly increase the risk of dysthymia, given the presence of MDD. Low parental warmth, from either mother or father, increases the risk of dysthymia. Highly threatening but short-lived threats (such as rape) are more specific for MDD than dysthymia. While for MDD more severe life events show the largest odds ratio versus controls, this was not seen for cases of MDD with or without dysthymia. Conclusions There are increased rates of stressful life events in MDD with dysthymia, but the impact of life events on susceptibility to dysthymia with MDD differs from that seen for MDD alone. The pattern does not fit a simple dose-response relationship, suggesting that there are moderating factors involved in the relationship between environmental precipitants and the onset of dysthymia. It is possible that severe life events in childhood events index a general susceptibility to chronic depression, rather than acting specifically as risk factors for dysthymia.
Perturbation of Auxin Homeostasis by Overexpression of Wild-Type IAA15 Results in Impaired Stem Cell Differentiation and Gravitropism in Roots
Da-Wei Yan, Jing Wang, Ting-Ting Yuan, Li-Wei Hong, Xiang Gao, Ying-Tang Lu
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0058103
Abstract: Aux/IAAs interact with auxin response factors (ARFs) to repress their transcriptional activity in the auxin signaling pathway. Previous studies have focused on gain-of-function mutations of domain II and little is known about whether the expression level of wild-type Aux/IAAs can modulate auxin homeostasis. Here we examined the perturbation of auxin homeostasis by ectopic expression of wild-type IAA15. Root gravitropism and stem cell differentiation were also analyzed. The transgenic lines were less sensitive to exogenous auxin and exhibited low-auxin phenotypes including failures in gravity response and defects in stem cell differentiation. Overexpression lines also showed an increase in auxin concentration and reduced polar auxin transport. These results demonstrate that an alteration in the expression of wild-type IAA15 can disrupt auxin homeostasis.
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