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Search Results: 1 - 10 of 55896 matches for " Jin Young Lee "
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Improvements to the Fluoride Reactivation Method by Simple Organic Extraction for Retrospective Detection of Exposure to the Organophosphorus Nerve Agents in Human Plasma  [PDF]
Jin Young Lee, Yong Han Lee
International Journal of Analytical Mass Spectrometry and Chromatography (IJAMSC) , 2014, DOI: 10.4236/ijamsc.2014.23007
Abstract: A rapid and simple organic extraction method for the determination of the chemical warfare agent, isopropyl methylphosphonofluoridate (sarin, GB) in human plasma has been developed using gas chromatography-tandem mass spectrometry (GC-MS/MS). In the course of method development, several organic solvents have been screened and chloroform show a low background and increase signal to noise ratio of GB among other organic solvents. Especially, the organic extraction method of reactivated GB from the human plasma has a 30% greater recovery yield than solid-phase ex-traction (SPE). This simple extraction method was successfully applied to the trace analysis of nerve agents in human plasma in the 3rd Organisation for the Prohibition of Chemical Weapons (OPCW) confidence building exercise on biomedical sample analysis.
Clinical Response to Treatment of Central Nervous System Tuberculosis in Non-Human Immunodeficiency Virus-Infected Adolescents and Adults  [PDF]
Jin Young Lee, Su Jin Lee, Ji Young Park, Min Jeong Kim
Journal of Tuberculosis Research (JTR) , 2016, DOI: 10.4236/jtr.2016.44020
Abstract: Introduction: More than half of patients with central nervous system tuberculosis (CNS TB) die or are left with severe neurological deficits despite receiving anti-TB treatment. Aims of the study: This study examined risk factors associated with poor response to initial treatment with four anti-TB drug regimens or three drug regimens with steroids as adjuvant therapy. Methods: This study analyzed medical records from two tertiary hospitals in Busan, Korea, between January 2009 and March 2012. The subjects were non-human immunodeficiency virus (HIV)-infected patients aged ≥16 years with clinical CNS TB. The subjects were divided into two groups according to response to treatment. Results: In totally, 52 patients with CNS TB were included. Of these, 14 (26%) and 38 (73%) showed poor and good responses, respectively. Of the patients with poor response, nine had stage III disease (64.3%) according to the British Medical Research Council (BMRC) staging system. A significantly higher proportion was seen in the good response group (p < 0.05). Patients with positive cerebrospinal fluid (CSF) acid-fast bacillus (AFB) culture, positive sputum AFB culture, positive CSF TB polymerase chain reaction (PCR) results, and brain tuberculoma had poorer responses (p < 0.05). Multivariate analysis to determine risk factors associated with poor response to anti-TB therapy revealed that a poor response was associated with stage III clinical signs upon diagnosis (odds ratio [OR] 32.122; 95% confidence interval [CI] 2.221 - 464.605), positive sputum AFB culture (OR 13.624; 95% CI 1.066 - 174.149), and tuberculoma on brain images (OR 45.714; 95% CI 1.893 - 1104.018). Conclusions: The results demonstrate the importance of identifying the severity of CNS TB and promptly administering anti-TB drugs. It is necessary to perform drug susceptibility testing for anti-TB drugs. Further studies are needed to confirm the correlations between risk factors associated with poor response and anti-TB drug resistance and the other risk factors.
Improvement of resolution in 2-D gel analysis by simple pre-treatment of human urine with EDTA  [PDF]
Jin-Woo Lee, Ju-Young Lee, Jinkyu Lim
Open Journal of Clinical Diagnostics (OJCD) , 2012, DOI: 10.4236/ojcd.2012.22008
Abstract: Regardless of thermodynamic stability, less complex proteome than plasma, convenient and noninvasive sampling of urine, reproducibility and comparability of the data among laboratories are challenges for the urine proteome analysis. Pretreatment of urine with 10 mM EDTA in conjunction with desalting methods to remove interfering molecules significantly improved the presentation of urine proteome on 2-D gels. Statistical analysis of the average ratio of the spot numbers on 2-D gels between EDTA-treated and non-treated samples were 1.35 ± 0.167, 1.26 ± 0.091, and 1.24 ± 0.095 for dialysis, ultrafiltration, and desalting column, respectively, with the p-value of 5.85 × 10–6 for the overall comparison. This result came from the fact that EDTA-treated samples showed better resolutions with less streaks and clearer spots on 2-D gels than the control samples. The results suggest that a simple and non-fractionating EDTA-treatment can be employed to the procedures for the high resolution 2-D gel analysis and other urinary proteomic analysis.
Bronchial Washing to Diagnose Smear-Negative Pulmonary Tuberculosis  [PDF]
Jin Young Lee
Journal of Tuberculosis Research (JTR) , 2019, DOI: 10.4236/jtr.2019.73014
Abstract: Introduction: Bronchoscopy with bronchial washing is useful for the diagnosis of pulmonary tuberculosis (TB) when sputum smears are negative. However, its indication has not been standardized. Therefore, we conducted a retrospective study to assess the diagnostic value of bronchial washing in patients suspected with pulmonary TB. Methodology: A retrospective analysis was performed on patients diagnosed with pulmonary TB in Kosin university gospel hospital, a tertiary hospital with 969 beds in South Korea, from March 2017 to December 2018. We obtained three serial sputum samples for acid-fast bacilli (AFB) smear and culture, and all patients underwent bronchoscopy with bronchial washing for AFB smear and culture. Results: Fifty-six patients were enrolled in the study. Smear-negative pulmonary TB (SNPT) was diagnosed in 42/56 (75%) patients. Among the patients with smear-positive sputum, 14/14 (100%) showed culture-positive sputum, while smear- and culture-positive bronchial washing were seen in 7/14 (50%) and 12/14 (85.7%) patients, respectively. Among the patients with SNPT, 17/42 (40.47%) had culture-negative sputum and were diagnosed using the bronchoscopic washing. Conclusions: For patients with smear-negative sputum, it is necessary to perform bronchoscopic washing to increase the diagnostic rate of pulmonary TB. To control the transmission of pulmonary TB, it is necessary to use a fast and accurate examination method.
Factors associated with obesity among Korean adolescents  [PDF]
Gyu Jin Heo, So Young Nam, Soo-Kyung Lee
Health (Health) , 2013, DOI: 10.4236/health.2013.58180

Obesity has been a great interest of public health. Studies simultaneously examining various factors associated with obesity among adolescents have been limited. Therefore, this study aimed to examine how various factors (socio-economic status, sex, age, diet, and physical activity) were simultaneously associated with obesity among Korean adolescents. This study analyzed two nationally representative datasets: 2008 Korea National Health and Nutrition Examination and Survey (KNHANES) and 2008 Korea Youth Risk Behavior Web-based Survey (KYRBWS). A total of 900 adolescents (12-18 year-old) in KNHANES and 74,451 adolescents in KYRBWS were included in statistical analyses with SPSS 19.0. Overweight (5.7%) and obesity (13.9%) rates were determined in KNHANES, and KYRBWS showed somewhat lower rates. No significant associations between the various factors and obesity were found in KNHANES. However, the analysis of KYRBWS confirmed higher obesity risk for boys, lower economic status, inferquent high-energy/low-nutrient type food consumption, practicing moderate-intensity physical activity less than five days per week, spending more than 2 hours sitting per day, and having tried exercise or diet for weight control (p < 0.05). The results from the two national datasets seemed to generally agree that many of the various obesity risk factors were important among Korean adolescents, although the associations were mostly not significant in KNHANES. It seemed that obese adolescents tried to practice good dietary behaviors, but not necessarily physical activity, known to reduce obesity risk. Obesity policies should continue to help adolescents achieve an active lifestyle and healthy eating behaviors.

The PL Characteristics of ZnO Thin Film on Flexible Polymer by Pulse Laser Deposition
Young Jin Choi,Cheon Lee
Transactions on Electrical and Electronic Materials , 2012,
Abstract: In this study, ZnO films have been grown on PES (polyethersulfone) of flexible polymer substrate by PLD (pulsed laserdeposition) and characterized for crystalline and optical properties. Growing conditions were changed with substratetemperatures ranging from 50 to 200℃ and laser power density ranging from 0.2 to 0.4 J/cm2. When ZnO thin filmsare deposited at low temperature with a small laser power density, the (002) peaks of XRD to signify the crystal qualityof ZnO thin films appear to be very weak and the (101) peaks to signify the chemical composition of oxygen andzinc are strong. The (002) peaks increase with the substrate temperature and laser power density because the energyneeded for the supply of the combination regarding zinc and oxygen has increased. In this study, the best conditionfor growing ZnO thin film on PES is at a substrate temperature of 200℃ and with a laser density of 0.3 J/cm2. Thecharacteristics of PL were measured by UV and green luminescence.
Light bending in radiation background
Jin Young Kim,Taekoon Lee
Physics , 2013, DOI: 10.1088/1475-7516/2014/01/002
Abstract: We consider the velocity shift of light in presence of radiation emitted by a black body. Within geometric optics formalism we calculate the bending angle of a light ray when there is a gradient in the energy density. We model the bending for two simplified cases. The bending angle is proportional to the inverse square power of the impact parameter ($\propto 1/b^2$) when the dilution of energy density is spherically symmetric. The bending angle is inversely proportional to the impact parameter ($\propto 1/b$) when the energy density dilutes cylindrically. Assuming that a neutron star is an isothermal black body, we estimate the order of magnitude for such bending angle and compare it with the bending angle by magnetic field.
Light bending in a Coulombic field
Jin Young Kim,Taekoon Lee
Physics , 2010, DOI: 10.1142/S0217732311035924
Abstract: The nonlinear Euler-Heisenberg interaction bends light toward an electric charge. The bending angle and trajectory of light in a Coulombic field are computed in geometric optics.
Light bending by nonlinear electrodynamics under strong electric and magnetic field
Jin Young Kim,Taekoon Lee
Physics , 2011, DOI: 10.1088/1475-7516/2011/11/017
Abstract: We calculate the bending angles of light under the strong electric and magnetic fields by a charged black hole and a magnetized neutron star according to the nonlinear electrodynamics of Euler-Heisenberg interaction. The bending angle of light by the electric field of charged black hole is computed from geometric optics and a general formula is derived for light bending valid for any orientation of the magnetic dipole. The astronomical significance of the light bending by magnetic field of a neutron star is discussed.
Korean Atmospheric Environmental Impact Assessment for Thermal Power Plant  [PDF]
Young Soo Lee, Ji Su Bae, Yu Jin Kang, Yu Jin Kang
Journal of Geoscience and Environment Protection (GEP) , 2014, DOI: 10.4236/gep.2014.24004

Korea has adopted Environmental Impact Assessment (hereafter “EIA”) system for more than 3 decades. There are 74 big projects subject to EIA according to (Environmental Impact Assessment Law (No. 10892). For thermal power plant of which output is more than 10 MW, EIA must be done by proponents. To assess impact on atmospheric environment, proponents utilize air dispersion models and to minimize the adverse impact on air quality, state-of-the-art add-on control technology is applied.

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