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Search Results: 1 - 10 of 35117 matches for " Jin Oh Park "
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Young walls and graded dimension formulas for finite quiver Hecke algebras of type $A^{(2)}_{2\ell}$ and $D^{(2)}_{\ell+1}$
Se-jin Oh,Euiyong Park
Mathematics , 2013,
Abstract: We study graded dimension formulas for finite quiver Hecke algebras $R^{\Lambda_0}(\beta)$ of type $A^{(2)}_{2\ell}$ and $D^{(2)}_{\ell+1}$ using combinatorics of Young walls. We introduce the notion of standard tableaux for proper Young walls and show that the standard tableaux form a graded poset with lattice structure. We next investigate Laurent polynomials associated with proper Young walls and their standard tableaux arising from the Fock space representations consisting of proper Young walls. Then we prove the graded dimension formulas described in terms of the Laurent polynomials. When evaluating at $q=1$, the graded dimension formulas recover the dimension formulas for $R^{\Lambda_0}(\beta)$ described in terms of standard tableaux of strict partitions.
Categorification of Quantum Generalized Kac-Moody Algebras and Crystal Bases
Seok-Jin Kang,Se-jin Oh,Euiyong Park
Mathematics , 2011,
Abstract: We construct and investigate the structure of the Khovanov-Lauda-Rouquier algebras $R$ and their cyclotomic quotients $R^\lambda$ which give a categrification of quantum generalized Kac-Moody algebras. Let $U_\A(\g)$ be the integral form of the quantum generalized Kac-Moody algebra associated with a Borcherds-Cartan matrix $A=(a_{ij})_{i,j \in I}$ and let $K_0(R)$ be the Grothedieck group of finitely generated projective graded $R$-modules. We prove that there exists an injective algebra homomorphism $\Phi: U_\A^-(\g) \to K_0(R)$ and that $\Phi$ is an isomorphism if $a_{ii}\ne 0$ for all $i\in I$. Let $B(\infty)$ and $B(\lambda)$ be the crystals of $U_q^-(\g)$ and $V(\lambda)$, respectively, where $V(\lambda)$ is the irreducible highest weight $U_q(\g)$-module. We denote by $\mathfrak{B}(\infty)$ and $\mathfrak{B}(\lambda)$ the isomorphism classes of irreducible graded modules over $R$ and $R^\lambda$, respectively. If $a_{ii}\ne 0$ for all $i\in I$, we define the $U_q(\g)$-crystal structures on $\mathfrak{B}(\infty)$ and $\mathfrak{B}(\lambda)$, and show that there exist crystal isomorphisms $\mathfrak{B}(\infty) \simeq B(\infty)$ and $\mathfrak{B}(\lambda) \simeq B(\lambda)$. One of the key ingredients of our approach is the perfect basis theory for generalized Kac-Moody algebras.
Effects of Extracorporeal Shockwave Therapy and Hand Massage on Body Composition and Serum Lipids According to Serum Cholesterol Level in Korean Women  [PDF]
Kyung Jin Lee, Jin Ik Park, Soo Yeon Oh
Journal of Cosmetics, Dermatological Sciences and Applications (JCDSA) , 2019, DOI: 10.4236/jcdsa.2019.92015
Abstract: Obesity, particularly abdominal obesity, increases the risk of cardiovascular disease (CVD). This study investigates the effects of six-week (twice a week, 12 sessions total) extracorporeal shockwave therapy (SWT) and hand massage therapy (HT) on body composition and serum lipids in overweight and obese Korean women aged between 35 and 59, according to their serum cholesterol level (≥200 mg/dL versus <200 mg/dL). After the program, weights decreased significantly in both the HT Group and SWT Group (p < 0.05); weights of those with cholesterol < 200 mg/dL significantly decreased in the HT Group (p = 0.038), while weights of those with cholesterol ≥ 200 mg/dL significantly decreased in the SWT Group (p = 0.001). BMIs decreased significantly in both the HT Group and the SWT Group (p < 0.05); BMIs of those with cholesterol < 200 mg/dL significantly decreased in the HT Group (p = 0.018), while BMIs of those with cholesterol ≥ 200 mg/dL significantly decreased in the SWT Group (p = 0.001). The body fat percentage of subjects significantly decreased only in the SWT Group (p = 0.027); the waist-hip ratio significantly decreased only in HT Group (p = 0.034). Serum cholesterol levels significantly decreased in those with cholesterol < 200 mg/dL in the HT Group (p < 0.05) and those with cholesterol ≥ 200 mg/dL in SWT Group (p = 0.055). Triglyceride significantly decreased in both those with cholesterol < 200 mg/dL and those with cholesterol ≥ 200 mg/dL, but did not significantly decrease in either subgroup of the HT Group. The study results suggest that SWT is effective in improving body measurements and serum lipids in those with cholesterol ≥ 200 mg/dL, while HT therapy is effective in those with cholesterol < 200 mg/dL. In conclusion, SWT and HT improved abdominal obesity by reducing body weight and waist circumference and helped improving serum lip index, suggesting the benefit for managing body measurements and serum lipids of overweight and obese individuals.
Solitons in a Grassmannian sigma-model Coupled to Chern-Simons Term
Jin-Ho Cho,Phillial Oh,Jeong-Hyuck Park
Physics , 2002, DOI: 10.1103/PhysRevD.66.025022
Abstract: We propose an exactly solvable Grassmannian sigma-model coupled to the Chern-Simons theory. In the presence of a novel topological term our model admits exact self-dual vortex solutions which are identical to those of pure Grassmannian model, but the topological charge has a physical meaning as a magnetic flux since the gauge field is no longer auxiliary. We also extend the theory to a noncommutative plane and analyze the BPS solutions.
Ultrasonography of normal and abnormal appendix in children
Noh Hyuck Park,Hwa Eun Oh,Hee Jin Park,Ji Yeon Park
World Journal of Radiology , 2011,
Abstract: Appendicitis is the most common acute surgical emergency of childhood. Since the original report by Puylaert in 1986, the use of ultrasonography in the diagnosis of appendicitis has been the subject of considerable study. Among the reported diagnostic criteria, the maximal outer diameter (MOD) of the appendix is accepted as the one of the most reliable criteria used to differentiate between a normal appendix and acute appendicitis. However, MOD measurement is subject to inaccuracies because luminal distention by non-compressible, non-inflammatory material such as fecal material, or increased maximal mural thickness due to reactive mucosal lymphoid hyperplasia, or a medical cause due to a generalized gastrointestinal disease, such as Crohn’s disease, can cause the measurement to exceed the upper limits of normality. The aim of this article is to introduce the spectrum of ultrasonographic findings in the normal and abnormal appendix and eventually to reduce unnecessary surgery in children.
Content Authoring and Cloud System Implementation for Smart Learning  [PDF]
Hyun-Seo Hwang, Jin-Tae Park, Kyeong-Taek Seo, Jun-Soo Yun, Il-Young Moon, Oh-Young Kwon, Byeong-Jun Kim
Journal of Computer and Communications (JCC) , 2015, DOI: 10.4236/jcc.2015.35017
Abstract:

In this paper, we implement a content authoring and cloud system for cloud-based smart cloud learning. With the advent of the smartphone and mobile devices such as tablets, the educational paradigm is also changing. Was using the computer to aid in the learning e-learning started in ICT education are evolving Over the variety, in recent years, combines smart learning and social learning, cloud-based smart devices in e-learning the concept of Smart Cloud Smart Education Services Learning was gives rise to the term. Smart Cloud and free running is always the knowledge content uploaded by anyone, anywhere, can also be shared with other users. A terminal and location, without limitations on time, are continuously available to the environment of a high- quality knowledge content was coming through a variety of smart media, open educational content platform is built over the level of the possible conditions than e-learning. In this paper, we develop applications and Web sites that can provide authored content for smart cloud learning. In addition, we have built the cloud for content management and the website that can share content with other users. In the future, should wish to study a way that can provide customized services over the learner analysis based on big data technology.

Construction of Irreducible Representations over Khovanov-Lauda-Rouquier Algebras of Finite Classical Type
Georgia Benkart,Seok-Jin Kang,Se-jin Oh,Euiyong Park
Mathematics , 2011,
Abstract: We give an explicit construction of irreducible modules over Khovanov-Lauda-Rouquier algebras $R$ and their cyclotomic quotients $R^{\lambda}$ for finite classical types using a crystal basis theoretic approach. More precisely, for each element $v$ of the crystal $B(\infty)$ (resp. $B(\lambda)$), we first construct certain modules $\nabla(\mathbf{a};k)$ labeled by the adapted string $\mathbf{a}$ of $v$. We then prove that the head of the induced module $\ind \big(\nabla(\mathbf{a};1) \boxtimes...\boxtimes \nabla(\mathbf{a};n)\big)$ is irreducible and that every irreducible $R$-module (resp. $R^{\lambda}$-module) can be realized as the irreducible head of one of the induced modules $\ind (\nabla(\mathbf{a};1) \boxtimes...\boxtimes \nabla(\mathbf{a};n))$. Moreover, we show that our construction is compatible with the crystal structure on $B(\infty)$ (resp. $B(\lambda)$).
TCF7L2 Modulates Glucose Homeostasis by Regulating CREB- and FoxO1-Dependent Transcriptional Pathway in the Liver
Kyoung-Jin Oh,Jinyoung Park,Su Sung Kim,Hyunhee Oh,Cheol Soo Choi,Seung-Hoi Koo
PLOS Genetics , 2012, DOI: 10.1371/journal.pgen.1002986
Abstract: Peripheral insulin resistance contributes to the development of type 2 diabetes. TCF7L2 has been tightly associated with this disease, although the exact mechanism was largely elusive. Here we propose a novel role of TCF7L2 in hepatic glucose metabolism in mammals. Expression of medium and short isoforms of TCF7L2 was greatly diminished in livers of diet-induced and genetic mouse models of insulin resistance, prompting us to delineate the functional role of these isoforms in hepatic glucose metabolism. Knockdown of hepatic TCF7L2 promoted increased blood glucose levels and glucose intolerance with increased gluconeogenic gene expression in wild-type mice, in accordance with the PCR array data showing that only the gluconeogenic pathway is specifically up-regulated upon depletion of hepatic TCF7L2. Conversely, overexpression of a nuclear isoform of TCF7L2 in high-fat diet-fed mice ameliorated hyperglycemia with improved glucose tolerance, suggesting a role of this factor in hepatic glucose metabolism. Indeed, we observed a binding of TCF7L2 to promoters of gluconeogenic genes; and expression of TCF7L2 inhibited adjacent promoter occupancies of CREB, CRTC2, and FoxO1, critical transcriptional modules in hepatic gluconeogenesis, to disrupt target gene transcription. Finally, haploinsufficiency of TCF7L2 in mice displayed higher glucose levels and impaired glucose tolerance, which were rescued by hepatic expression of a nuclear isoform of TCF7L2 at the physiological level. Collectively, these data suggest a crucial role of TCF7L2 in hepatic glucose metabolism; reduced hepatic expression of nuclear isoforms of this factor might be a critical instigator of hyperglycemia in type 2 diabetes.
Type 2 diabetes genetic association database manually curated for the study design and odds ratio
Ji Lim, Kyung-Won Hong, Hyun-Seok Jin, Yang Kim, Hun Park, Bermseok Oh
BMC Medical Informatics and Decision Making , 2010, DOI: 10.1186/1472-6947-10-76
Abstract: The list of publications used in this study was collected from the HuGE Navigator, which is an online database of published genome epidemiology literature. Because type 2 diabetes genetic association database (T2DGADB) aims to provide specialized information on the genetic risk factors involved in the development of type 2 diabetes, 701 of the 1,771 publications in the type 2 Diabetes case-control study for the development of the disease were extracted.In the database, the association results were grouped as either positive or negative. The gene and SNP names were replaced with gene symbols and rsSNP numbers, the association p-values were determined manually, and the results are displayed by graphs and tables. In addition, the study design in publications, such as the population type and size are described. This database can be used for research purposes, such as an association and functional study of type 2 diabetes related genes, and as a primary genetic resource to construct a diabetes risk test in the preparation of personalized medicine in the future.The prevalence of type 2 diabetes has reached epidemic proportions worldwide with the largest increase in Asia, Africa and South America [1]. The incidence of life-threatening complications of diabetes, such as retinopathy, nephropathy and lower-limb amputation, caused by the continued exposure of tissue to the high glucose has increased [2]. Since hyperglycemia can be prevented and reversed significantly by lifestyle changes, including the exercise and nutrition, diabetes risk tests, such as one provided by the American Diabetes Association http://www.diabetes.org webcite, have been used to alarm various high risk groups. However, an increase in the incidence of diabetes has not been stopped over the last decade, highlighting the need for new approaches. According to the World Health Organization (WHO), the number of people with type 2 diabetes worldwide was approximately 170 million and 280 million in 2000 and 20
Development of selective blockers for Ca2+-activated Cl- channel using Xenopus laevis oocytes with an improved drug screening strategy
Soo-Jin Oh, Jung Park, Sungyu Han, Jae Lee, Eun Roh, C Justin Lee
Molecular Brain , 2008, DOI: 10.1186/1756-6606-1-14
Abstract: Oocytes were prepared with a treatment of Ca2+ ionophore, which was followed by a treatment of thapsigargin which depletes Ca2+ stores to eliminate any contribution of Ca2+ release. TEVC was performed with micropipette containing chelerythrine to prevent PKC dependent run-up or run-down. Under these conditions, Ca2+-activated Cl- currents induced by bath application of Ca2+ to oocytes showed stable peak amplitude when repetitively activated, allowing us to test several concentrations of a test compound from one oocyte. Inhibitory activities of commercially available blockers and synthesized anthranilic acid derivatives were tested using this method. As a result, newly synthesized N-(4-trifluoromethylphenyl)anthranilic acid with trifluoromethyl group (-CF3) at para position on the benzene ring showed the lowest IC50.Our results provide an optimal drug screening strategy suitable for high throughput screening, and propose N-(4-trifluoromethylphenyl)anthranilic acid as an improved CaCC blocker.Ca2+-activated Cl- channels (CaCCs) are anion-selective channels that can be activated by an increase in cytosolic Ca2+. CaCCs serve a number of important physiological roles in a variety of cell types. These functions include vascular tone regulation, cardiac excitability, smooth muscle contraction, fast block of polyspermy in certain eggs [1]. CaCCs are also known to regulate epithelial secretion of electrolytes and water in kidneys, airways, intestines, pancreas and salivary glands [1]. In addition, CaCCs appear to participate in signal processing of olfactory transduction, photo receptor light response, gustation and somaesthetic sensation by regulating neuronal cell excitability. CaCC currents in non-sensory neurons of the spinal cord and the autonomic nervous system were also reported, and further investigation may prove an even more extensive expression in the nervous system [2]. Despite this physiological importance of CaCC, the channel remains poorly understood at the mo
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