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Search Results: 1 - 10 of 11459 matches for " Jianyong Cai "
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Preprocessing of Separating Leukocytes Based on Setting Parameters of Lightness Transformation  [PDF]
Jianyong Cai, Lili Luo, Rongtai Cai, Lijin Lin, Juan Cai
Journal of Signal and Information Processing (JSIP) , 2013, DOI: 10.4236/jsip.2013.44051
Abstract: This paper proposed a new algorithm to separate leukocytes from cytological image by setting parameters of lightness transformation based on the RGB color space, which can make the targets’ color in different areas. In our procedure, an operator is employed in using color features. According to their histogram distribution of hue component in HSL color space after enhancing the contrast of image in RGB color space, the threshold of segmentation between leukocyte and erythrocyte could be achieved well. Especially, this algorithm is more efficient than monochrome for leukocyte segmentation, and the results of experiments show that it provides a good tool for cytological image, which can increase accuracy of segmentation of leukocyte.
On Two Cryogenic Systems of High Purity Germanium Detector  [PDF]
Jianyong Zhang, Xiao Cai, Xiaohu Mo
Detection (Detection) , 2013, DOI: 10.4236/detection.2013.12003
Abstract: Two cryogenic systems of high purity germanium detector, liquid nitrogen and mechanical cooler, are expounded, to- gether with explanations of merits and demerits for each kind of cooling methods. The resolutions of detector to the characteristic lines of 152Eu under different cooling conditions are studied. The laboratory results indicate that the me- chanical cooler (X-Cooler II) is an ideal replacement candidate for the liquid nitrogen cooling system that is being util- ized by BEMS at BEPC-II.
Improvement of Beam Energy Measurement System for BES-III  [PDF]
Jianyong Zhang, Xiao Cai, Xiaohu Mochizuki, Muchnoi Nickolai, Achasov Mikhail, Elena Abakumova, Harris Fred
World Journal of Nuclear Science and Technology (WJNST) , 2016, DOI: 10.4236/wjnst.2016.64025
Abstract: The beam energy measurement system is significant and profit for both BES-III detector and BEPC-II accelerator. The detection of the high energy scattering photons is realized by virtue of the Compton backscattering principle. Many advanced techniques and precise instruments are employed to acquire the highly accurate measurement of positron/electron beam energy. During five years’ running period, in order to satisfy the requirement of data taking and enhance the capacity of measurement itself, the upgradation of system is continued, which involves the components reformation of laser and optics subsystem, replacement of view-port of the laser to vacuum insertion subsystem, the usage of electric cooling system for high purity germanium detector, and the refinement of data acquisition and processing subsystem. The upgrading of system guarantees the smooth and effective measuring of beam energy at BEPC-II and accommodates the accurate offline energy values for further physics analysis at BES-III.
Thermal stability, pH dependence and inhibition of four murine kynurenine aminotransferases
Qian Han, Tao Cai, Danilo A Tagle, Jianyong Li
BMC Biochemistry , 2010, DOI: 10.1186/1471-2091-11-19
Abstract: This study concerns the functional expression and comparative characterization of KAT I, II, III, and IV from mice. At the applied test conditions, equimolar tryptophan with kynurenine significantly inhibited only mouse KAT I and IV, equimolar methionine inhibited only mouse KAT III and equimolar aspartate inhibited only mouse KAT IV. The activity of mouse KAT II was not significantly inhibited by any proteinogenic amino acids at equimolar concentrations. pH optima, temperature preferences of four KATs were also tested in this study. Midpoint temperatures of the protein melting, half life values at 65°C, and pKa values of mouse KAT I, II, III, and IV were 69.8, 65.9, 64.8 and 66.5°C; 69.7, 27.4, 3.9 and 6.5 min; pH 7.6, 5.7, 8.7 and 6.9, respectively.The characteristics reported here could be used to develop specific assay methods for each of the four murine KATs. These specific assays could be used to identify which KAT is affected in mouse models for research and to develop small molecule drugs for prevention and treatment of KAT-involved human diseases.The aminotransferase capable of catalyzing the transamination of kynurenine to kynurenic acid (KYNA) using various co-substrates, has commonly been termed kynurenine aminotransferase (KAT). KYNA is the only known endogenous antagonist of the N-methyl-D-aspartate subtype of glutamate receptors[1-4]. It is also an antagonist of the α7-nicotinic acetylcholine receptor[5-8]. In addition, KYNA is identified as an endogenous ligand for an orphan G-protein-coupled receptor (GPR35) that is predominantly expressed in immune cells[9]. Abnormal concentration of KYNA in cerebrospinal fluid/brain tissue has been observed in patients with mental and neurological disorders, including the Huntington's disease, Alzheimer's disease, schizophrenia, multiple sclerosis and others (for a review see [10]). These data suggest that KYNA, acting as an endogenous modulator of glutamatergic and cholinergic neurotransmission, may be functional
(E)-N′-[4-(Dimethylamino)benzylidene]-4-methylbenzohydrazide methanol monosolvate
Huanyu Liu,Yanchun Cai,Jianyong Wu,Zhuolin Li
Acta Crystallographica Section E , 2011, DOI: 10.1107/s1600536811029394
Abstract: In the title compound, C17H19N3O·CH3OH, the hydrazone molecule exists in a trans geometry with respect to the methylidene unit and the dihedral angle between the two substituted benzene rings is 42.6 (2)°. In the crystal, the components are linked through N—H...O and O—H...O hydrogen bonds, forming [100] chains of alternating hydrazone and methanol molecules.
Primary cardiac osteosarcoma in a 42-year-old woman
Honghe Luo, Yiyan Lei, Chunhua Su, Lie Cai, Tao Wang, Jianyong Zou, Zhenguang Chen
Journal of Cardiothoracic Surgery , 2010, DOI: 10.1186/1749-8090-5-120
Abstract: Although osteosarcoma is a common tumor of the skeletal system, primary cardiac osteosarcoma is an extremely rare malignant disease with nonspecific symptoms, making early diagnosis a challenge. We describe here a 42-year-old woman with a primary cardiac osteosarcoma, which was surgically removed by cardiopulmonary bypass. Two years later, she has shown no evidence of tumor recurrence.A 42-year-old woman was admitted to our hospital complaining of chest pain, shortness of breath and weight loss. Physical examination revealed an extra systolic murmur at the cardiac apex, with NYHA stage III. An electrocardiogram revealed sinus bradycardia, and echocardiography showed a pedunculated mass in her left atrium with weak aortic and mitral valve insufficiency, similar to myxoma (Figure 1). Computed tomography revealed a mass, 65 × 20 × 20 mm in size and attached to the posterior wall of the left atrium, without calcification or pericardial effusion. The patient was diagnosed with a primary cardiac tumor and was referred for surgical removal of the mass. During surgery, a tumor measuring 50 × 20 × 20 mm was found, with a stalk attached to the posterior wall of the left atrium and near the orifice of the left pulmonary vein. The mass was removed and a partial endocardiectomy was performed. Pathological examination of the tumor showed that the malignant cells were irregularly osteoid without polygonal to stellate shapes. The tumor cells were strongly stained with antibodies to the osteoclast marker CD68 and vimentin, but were weakly stained with antibodies to CK, EMA, S-100, and CD34 (Figure 1). Based on these histological and immunohistochemical findings, the final diagnosis was primary cardiac osteosarcoma [1,2]. At present, 2 years after surgical removal of the tumor, the patient remains healthy with no evidence of tumor recurrence.Most primary cardiac tumors are myxomas, and only a very small proportion of these cardiac tumors (< 0.28%) are malignant [3]. Only a few isolat
Effects of ischemic preconditioning on ischemia/reperfusion-induced arrhythmias by upregulatation of connexin 43 expression
Zhenguang Chen, Honghe Luo, Mei Zhuang, Lie Cai, Chunhua Su, Yiyan Lei, Jianyong Zou
Journal of Cardiothoracic Surgery , 2011, DOI: 10.1186/1749-8090-6-80
Abstract: Thirty-three rabbit models of myocardial hypertrophy were randomly divided into three groups of 11 each: non-ischemia-reperfusion group (group A), ischemia-reperfusion group (group B), and ischemic preconditioning group (group C). Another ten healthy rabbits with normal myocardium served as the healthy control group. Rabbit models of myocardial hypertrophy were induced by abdominal aortic banding. Surface electrocardiogram (ECG) was recorded and Curtis-Ravingerova score was used for arrhythmia quantification. Connexin 43 (Cx43) expression was assessed by immunohistochemistry.Ratios of heart weight to body weight and left ventricular weight to body weight increase significantly in the three groups compared with the healthy control group (p < 0.05). Arrhythmia incidence in group C is significantly lower than group B (p < 0.05). Curtis-Ravingerova score in group C is lower than group B (p < 0.05). Cx43 expression area in group A is smaller by comparison with the healthy control group (p < 0.05). Cx43 expression area and fluorescence intensity in group B are reduced by 60.9% and 23.9%, respectively, compared with group A (p < 0.05). In group C, Cx43 expression area increases by 32.5% compared with group B (p < 0.05), and decreases by 54.8% compared with group A (p < 0.05).The incidence of ischemia/reperfusion-induced arrhythmias in hypertrophic rabbit hearts decreases after IP, which plays an important protecting role on the electrophysiology of hypertrophied myocardium by up-regulating the expression of Cx43.Various degrees of myocardial injury are present in hypertrophic hearts of patients undergoing open heart surgery. The hypertrophied myocardium differs from normal myocardium in myocyte architecture and myocardial blood supply. The decline of tolerance to ischemia-reperfusion injury of hypertrophied myocardium, due to pathological changes in cellular architecture and metabolism, is one of the causes of post-ischemic reperfusion arrhythmias. For the hypertrophied he
Thermodynamic Geometry and Critical Behavior of Black Holes
Jianyong Shen,Rong-Gen Cai,Bin Wang,Ru-Keng Su
Physics , 2005, DOI: 10.1142/S0217751X07034064
Abstract: Based on the observations that there exists an analogy between the Reissner-Nordstr\"om-anti-de Sitter (RN-AdS) black holes and the van der Waals-Maxwell liquid-gas system, in which a correspondence of variables is $(\phi, q) \leftrightarrow (V,P)$, we study the Ruppeiner geometry, defined as Hessian matrix of black hole entropy with respect to the internal energy (not the mass) of black hole and electric potential (angular velocity), for the RN, Kerr and RN-AdS black holes. It is found that the geometry is curved and the scalar curvature goes to negative infinity at the Davies' phase transition point for the RN and Kerr black holes. Our result for the RN-AdS black holes is also in good agreement with the one about phase transition and its critical behavior in the literature.
The phase transition and the Quasi-Normal Modes of black Holes
Jianyong Shen,Bin Wang,Chi-Yong Lin,Rong-Gen Cai,Ru-Keng Su
Physics , 2007, DOI: 10.1088/1126-6708/2007/07/037
Abstract: We reexamined the argument that the quasinormal modes could be a probe of the phase transition of a topological black hole to a hairy configuration by investigating general scalar perturbations. We found further evidence in the quasinormal modes for this phase transition. For the general black hole configurations, we observed that although the quasinormal modes can present us different phases of different configurations, there is no dramatic change in the slope of quasinormal frequencies at the critical point of the phase transition. More detailed studies of quasinormal modes are needed to reveal the subtle behavior of the phase transition.
Application of nanomaterials in two-terminal resistive-switching memory devices
Jianyong Ouyang
Nano Reviews , 2010, DOI: 10.3402/nano.v1i0.5118
Abstract: Nanometer materials have been attracting strong attention due to their interesting structure and properties. Many important practical applications have been demonstrated for nanometer materials based on their unique properties. This article provides a review on the fabrication, electrical characterization, and memory application of two-terminal resistive-switching devices using nanomaterials as the active components, including metal and semiconductor nanoparticles (NPs), nanotubes, nanowires, and graphenes. There are mainly two types of device architectures for the two-terminal devices with NPs. One has a triple-layer structure with a metal film sandwiched between two organic semiconductor layers, and the other has a single polymer film blended with NPs. These devices can be electrically switched between two states with significant different resistances, i.e. the ‘ON’ and ‘OFF’ states. These render the devices important application as two-terminal non-volatile memory devices. The electrical behavior of these devices can be affected by the materials in the active layer and the electrodes. Though the mechanism for the electrical switches has been in argument, it is generally believed that the resistive switches are related to charge storage on the NPs. Resistive switches were also observed on crossbars formed by nanotubes, nanowires, and graphene ribbons. The resistive switches are due to nanoelectromechanical behavior of the materials. The Coulombic interaction of transient charges on the nanomaterials affects the configurable gap of the crossbars, which results into significant change in current through the crossbars. These nanoelectromechanical devices can be used as fast-response and high-density memory devices as well. Dr. Jianyong Ouyang received his bachelor degree from the Tsinghua University in Beijing, China, and MSc from the Institute of Chemistry, Chinese Academy of Science. He received his PhD from the Institute for Molecular Science, Graduate University for Advanced Studies, Japan. After working as an assistant professor at the Japanese Advanced Institute of Science and Technology, and subsequently as a postdoctoral researcher at the University of California, Los Angeles, he joined as an assistant professor in 2006 at the National University of Singapore. His current research interests include organic/polymeric electronic materials and devices, nanometer materials and devices, energy materials and devices.
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