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Search Results: 1 - 10 of 714844 matches for " Jhon A; LOPERA M. "
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OBTENCIóN DE OLEORRESINA DE PIMENTóN (Capsicum annuum L.) EXTRACTION OF OLEORESIN FROM SWEET PEPPER (Capsicum annuum L.)
Jhon A CARDONA. R.,Guillermo L. LOPERA M.,Alejandra M. MONTOYA R.,Ana M. MONTOYA V.
Vitae , 2006,
Abstract: La oleorresina de pimentón (Capsicum annuum L.), la cual contiene fundamentalmente carotenoides, capsaicinoides y algunas vitaminas, tradicionalmente se usa en la industria alimentaria. ésta se obtiene mediante un proceso con las siguientes etapas: a) escaldado, b) troceado, c) secado, d) molienda, y e) extracción con solventes volátiles (hexano, acetona, acetato de etilo). Los pigmentos que se extraen se analizan mediante HPLC en fase reversa y se comparan con la oleorresina de paprika comercial importada por la empresa TECNAS . El rendimiento que se obtiene en el laboratorio está entre el 3 y 6%. Los resultados muestran la importancia del escaldado y del secado: el escaldado permite alcanzar una humedad del 13,56% en 320 min (sin escaldar en el mismo tiempo se llega al 21,01%) y el secado posibilita la extracción con solventes. Oleoresin from sweet pepper (Capsicum annuum L.), which contains mainly carotenoids, capsaicinoids and some vitamins, has been currently used in the food industry. and is obtained with the following procedure: a) scalding, b) chopping, c) drying, d) milling, and e) solvent extraction (hexane, acetone, ethyl acetate). Extracted pigments are analyzed using reverse phase HPLC and the results are compared with the oleoresin obtained from comercial paprika imported by TECNAS . The yield achieved in the laboratory is 3-6%. The results show that scalding and drying are important: the scalding allows to reach an humidity of 13.56% in 320 min (without scalding the humidity reached is 21.01%) and the drying allows extraction with solvents.
OBTENCIóN DE OLEORRESINA DE PIMENTóN (Capsicum annuum L.)
CARDONA. R.,Jhon A; LOPERA M.,Guillermo L.; MONTOYA R.,Alejandra M.; MONTOYA V.,Ana M.; PE?A A.,Juan D.; GIL M.,Manuela; BENAVIDES,Julie F.; R.,María; RíOS,Luis A.; RESTREPO V.,Gloria M.;
Vitae , 2006,
Abstract: oleoresin from sweet pepper (capsicum annuum l.), which contains mainly carotenoids, capsaicinoids and some vitamins, has been currently used in the food industry. and is obtained with the following procedure: a) scalding, b) chopping, c) drying, d) milling, and e) solvent extraction (hexane, acetone, ethyl acetate). extracted pigments are analyzed using reverse phase hplc and the results are compared with the oleoresin obtained from comercial paprika imported by tecnas?. the yield achieved in the laboratory is 3-6%. the results show that scalding and drying are important: the scalding allows to reach an humidity of 13.56% in 320 min (without scalding the humidity reached is 21.01%) and the drying allows extraction with solvents.
Humoral Immune Response to the Anti-malaria Vaccine SPf66 in the Colombian Atrato River Region
Lopera, TM;Restrepo, M;Blair, S;García, HI;
Memórias do Instituto Oswaldo Cruz , 1998, DOI: 10.1590/S0074-02761998000400015
Abstract: the immunogenicity of anti-malaria synthetic vaccine spf66 was tested in a region of the colombian middle atrato river. the specific serum antibodies against spf66 were quantified in vaccinees and placebo injected controls for a two-years period post-immunization. the frequency of individuals showing seroconversion of anti-spf66 antibodies three months after completion of the immunization schedule was higher in vaccinees than in controls (52.7% and 25.5%, respectively, p<0.01). however, an over than four-fold increase of the specific anti-spf66 antibody titers was observed only in 1.4% of vaccinees and 0.2% of the controls (p<0.01). the anti-spf66 antibody titers augmented in vaccinees from first dose application to three months after the third dose, continuously decreasing thereafter to reach below baseline values two years after completion of the immunization schedule. the results show that spf66 has very low immunogenicity and induces a short term humoral immune response (six months).
Humoral Immune Response to the Anti-malaria Vaccine SPf66 in the Colombian Atrato River Region
Lopera TM,Restrepo M,Blair S,García HI
Memórias do Instituto Oswaldo Cruz , 1998,
Abstract: The immunogenicity of anti-malaria synthetic vaccine SPf66 was tested in a region of the Colombian middle Atrato river. The specific serum antibodies against SPf66 were quantified in vaccinees and placebo injected controls for a two-years period post-immunization. The frequency of individuals showing seroconversion of anti-SPf66 antibodies three months after completion of the immunization schedule was higher in vaccinees than in controls (52.7% and 25.5%, respectively, p<0.01). However, an over than four-fold increase of the specific anti-SPf66 antibody titers was observed only in 1.4% of vaccinees and 0.2% of the controls (p<0.01). The anti-SPf66 antibody titers augmented in vaccinees from first dose application to three months after the third dose, continuously decreasing thereafter to reach below baseline values two years after completion of the immunization schedule. The results show that SPf66 has very low immunogenicity and induces a short term humoral immune response (six months).
CARACTERIZACIóN CINéTICA DE DIFERENTES POLIMORFOS DE FENITOINA POR MEDIO DE LA TéCNICA DE DSC
FLOREZ A,Oscar A; TOBóN Z,Gloria E; LOPERA G,Erika M;
Vitae , 2009,
Abstract: the activation energy variation can be used as a quick measure to differentiate polymorphs of active pharmaceutical ingredients. in this paper diverse phenytoin crystal habits have been obtained through processes of recrystallization in different solvents. some of these solids differ in melting point by dsc, but are similar in xrd and ft-ir. from the results of melting point, 4 solids are selected by presenting the most dissimilar values. their activation energy (ea) is determined by dsc technique, using 3 theoretical isoconversional nonisothermal models and it is found even that 23 kcal/ mol of difference separate the most extreme values.
CARACTERIZACIóN CINéTICA DE DIFERENTES POLIMORFOS DE FENITOINA POR MEDIO DE LA TéCNICA DE DSC KINETIC CHARACTERIZATION OF DIFFERENT PHENYTOIN POLYMORPHS BY DSC TECHNIQUE
Oscar A FLOREZ A,Gloria E TOBóN Z,Erika M LOPERA G
Vitae , 2009,
Abstract: La variación de la energía de activación puede ser utilizada como una medida ágil para diferenciar polimorfos de los ingredientes activos farmacéuticos. En este trabajo se obtienen diversos hábitos cristalinos de fenitoína mediante procesos de recristalización en diferentes solventes. Algunos de estos sólidos presentan diferencias en el punto de fusión por DSC, pero son similares en DRX e IR-TF. A partir de los resultados del punto de fusión, se seleccionan 4 sólidos por presentar los valores más disímiles, luego su energía de activación (Ea) se determina por medio de la técnica DSC, empleando 3 modelos teóricos de isoconversión no isotérmicos, encontrándose hasta 23 Kcal/mol de diferencia entre los valores más extremos. The activation energy variation can be used as a quick measure to differentiate polymorphs of active pharmaceutical ingredients. In this paper diverse phenytoin crystal habits have been obtained through processes of recrystallization in different solvents. Some of these solids differ in melting point by DSC, but are similar in XRD and FT-IR. From the results of melting point, 4 solids are selected by presenting the most dissimilar values. Their activation energy (Ea) is determined by DSC technique, using 3 theoretical isoconversional nonisothermal models and it is found even that 23 Kcal/ mol of difference separate the most extreme values.
Acceso de las personas con VIH al sistema de salud colombiano y sus costos relacionados desde una perspectiva individual y familiar, Bogotá, 20I0
Lopera-Medina,Mónica María; Martínez-Escalante,Jorge; Ray-Einarson,Thomas;
Revista Gerencia y Políticas de Salud , 2011,
Abstract: to determine the access to healthcare for hiv patients and the associated costs in bogotá, we developed a protocol using a mixed design. the quantitative phase comprised a cross-sectional study with a convenience sample of 540 adults with hiv. for the qualitative phase, a phenomenological study with 20 individuals was undertaken. 95% of participants had health insurance, but we found many structural, operative and human failures that imposed barriers to comprehensive treatment, as well as a complicated process to guarantee the rights for health. the direct cost assumed by individuals with htv or their families was $65,000 cop monthly, representing 11-16% of their income. indirect costs were 2.2 times higher. access to healthcare influenced their medical condition as well as the burden of illness in terms of direct and indirect costs.
VARIABILIDAD GENéTICA DE LOTES DE Brycon orbignyanus UTILIZADOS EN PROGRAMAS DE REPOBLAMIENTO: MANEJO Y CONSERVACIóN
LOPERA-BARRERO NELSON M,PEREIRA RIBEIRO RICARDO,NARDEZ SIROL RODOLFO,POVH JAYME A
Acta Biológica Colombiana , 2008,
Abstract: Alteraciones ambientales causadas por el calentamiento global y principalmente causa-das por la acción del hombre, han reducido poblaciones naturales de peces. Como forma de conservación, programas de repoblamiento han sido utilizados; sin embargo, sin una debida orientación científica, estas medidas pueden generar disturbios genéticos sobre la diversidad genética de poblaciones de peces naturales y sobre el ecosistema. El objetivo de este estudio fue estimar y analizar la variabilidad genética de dos lotes y una progenie de Brycon orbignyanus utilizados en programas de repoblamiento, utilizando el marcador molecular RAPD (Random Amplified Polymorphic DNA). Cincuenta y ocho reproductores de dos lotes (A y C) y 30 larvas de la progenie del lote A (B) pertenecientes a la Esta o de Aqüicultura e Hidrologia da Duke Energy Internacional (Gera o Parana-panema; S o Paulo, Brasil) fueron analizados. Los resultados de variabilidad genética estimados por el índice de diversidad de Shannon (A: 0,3184; B: 0,3433 y C: 0,3687) y por el porcentaje de fragmentos polimórficos (A: 54,02%; B: 57,47% y C: 58,62%) mostraron que la variabilidad genética fue mantenida en la progenie, debido posiblemente al adecuado manejo reproductivo y al efecto fundador. Por el contrario, la variabilidad encontrada entre los dos lotes de reproductores indica una similaridad genética, a pesar de ser originarios de diferentes pisciculturas. Este resultado es comprobado en el valor moderado de diferenciación genética encontrado (0,0968), en el alto Nm (4,67) y en el dendrograma, que sugieren que los lotes poseen un pool genético similar
MáS ALLá DEL MOLESTO RONQUIDO: SíNDROME DE APNEA OBSTRUCTIVA DEL SUE O Y SU PELIGROSA ASOCIACIóN CON EL SíNDROME METABóLICO ALéM DO HUM IRRITANTE: SíNDROME DA APNéIA OBSTRUTIVA DO SONO E ASSOCIA O PERIGOSA COM SíNDROME METABóLICA BEHIND BOTHERSOME SNORING: OBSTRUCTIVE SLEEP APNEA SYNDROME AND ITS DANGEROUS ASSOCIATION WITH METABOLIC SíNDROME
JAMES M. YURGAKY S.,ALIRIO BASTIDAS,JHON A. CONTA,JAIME A. MONTA?A
Revista Med , 2011,
Abstract: El síndrome de apnea hipoapnea obstructiva del sue o (SAHOS) es una enfermedad frecuente que afecta alrededor del 5 % de la población general y a casi la mitad de los pacientes obesos. La asociación de SAHOS con obesidad ha sido bien establecida desde que fue descrito por primera vez; durante los últimos a os ha sido creciente la producción literaria que asocia la hipoxemia con un incremento de la enfermedad cardiovascular y metabólica, las cuales finalmente originan un mayor riesgo cardiovascular en los pacientes afectados no necesariamente obesos. Debido a la presencia de hipoxemia secundaria a la obstrucción mecánica del flujo aéreo que se encuentra en los pacientes afectados por el síndrome de apnea hipoapnea obstructiva del sue o, se desencadenan eventos fisiopatogénicos tales como la liberación de radicales libres, la disminución de la expresión de algunas enzimas importantes para el clivaje del colesterol y la producción de óxido nítrico y el aumento en la producción de mediadores inflamatorios que generan disrupción de vías metabólicas y endocrinológicas, lo cual ocasiona un incremento en el riesgo de sufrir diabetes mellitus, resistencia a la insulina, hipertensión arterial, obesidad y dislipidemia aterogénica. O síndrome da apnéia obstrutiva do sono (SAOS) é uma doen a comum que afeta cerca de 5% da popula o geral e quase a metade dos pacientes obesos; a associa o de SAOS com a obesidade tem sido bem estabelecida desde que foi descrita pela primeira vez; a produ o literária que associa a hipoxemia com um aumento da doen a cardiovascular e metabólica nos últimos anos tem sido crescente, o que acabou por dar origem a um maior risco cardiovascular em pacientes afetados, n o necessariamente obesos. Devido à presen a de hipoxemia secundária à obstru o mecanica do fluxo de ar encontrado em pacientes afetados pela síndrome da apnéia hipopnéia obstrutiva do sono, se desencadena eventos fisiopatológicos, tais como radicais livres, diminui o da express o de várias enzimas para a clivagem de colesterol e produ o de óxido nítrico e aumento da produ o de mediadores inflamatórios que produzem interrup o de vias metabólicas e endócrinas que resultam en um aumento deo risco de diabetes mellitus, resistência à insulina, hipertens o, obesidade e dislipidemia aterogênica. Obstructive sleep apnea syndrome (OSAS) is a frequent disease that affects around 5% of the general population and almost half the obese patients. The association between OSAS and obesity has been well established since it was described for the first time. in the last few years a lot of
Algoritmo Neuro-Difuso para la Detección y Clasificación de Fallas en Líneas de Transmisión Eléctrica Usando ANFIS.
Jhon A. Calderón,Germán Zapata M.,Demetrio A. Ovalle C.
Avances en Sistemas e Informática , 2007,
Abstract: The detection and classification of faults in electric transmission lines is an essential task to be performed. Within an electric power system a diversity of faults which come from low impedance faults (LIFs) to high impedance faults (HIFs) are exhibited. Last faults are more difficult to be detected due to the use of conventional distance relays. In addition, when they are not detected irreversible consequences are presented into the system. From above, it is inferred that taking into account that HIFs are less frequent than LIFs it appears essential to guaranty that any protection device must be able to satisfactorily detect both kind of electric faults. The aim of this paper is to present an algorithm to detect and classify both kind of faults LIFs and HIFs using ANFIS (Adaptive Network-based Fuzzy Inference System). The inputs for ANFIS are based on RMS (Root-Mean-Square) values from 3-phase and zero-sequence current. The obtained results show that an ANFIS model can detect and classify faults in a precise way including (LIFs y HIFs) in between a half cycle time.
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