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Search Results: 1 - 10 of 22405 matches for " Jeong-Hoon Kim "
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Cultivation characteristics and flavonoid contents of wormwood (Artemisia montana Pamp.)  [PDF]
Yong Joo Kim, Jeong-Hoon Lee, Sun-Ju Kim
Journal of Agricultural Chemistry and Environment (JACEN) , 2013, DOI: 10.4236/jacen.2013.24017
Abstract: The aim of this study was to establish the optimum harvesting time and the content of flavonoids in the leaves, stems, and roots of Artemisia montana Pamp. A. montana was monitored from June to October in 2012. The yield of A. montana at high density (30 × 10 cm) was higher than that of A. montana at low density (30 × 20 and 30 cm). Yield in terms of dry weight was increased with an extended growth period and development stage. High yield achieved at 2580 and 2757 kg?10 a?1 in September and October, respectively. Among the leaves, stems, and underground plant organs, jaceosidin and eupatilin were mainly detected in the leaves, and the highest levels were observed in June, at values of 66.6 and 158.2 mg?100 g?1, respectively. In contrast, apigenin was the major compound detected in the underground plant organs, with levels ranging from 21.2 to 29.5 mg?100 g?1 until September. Therefore, optimal harvest times were between September and October, generating a high yield and adding economic value although a higher level of total flavonoids was observed in crops harvested in June.
An Auto-Configuration of 4M Group Management Using Wireless Sensor Networks  [PDF]
Suk-Keun Cha, Jeong-Hoon Lee, Han Gyu Kim, Joon Jae Yoo, Jung Hoon Kang, Dong Hoon Kim, Jun Yeob Song
Wireless Sensor Network (WSN) , 2010, DOI: 10.4236/wsn.2010.24052
Abstract: The first tier of automotive manufacturers has faced to pressures about move, modify, updating tasks for manufacturing resources in production processes from demand response of production order sequence for motor company and process innovation purpose for productivity. For meets this requirements, it has to require absolutely lead time to re-wiring of physical interface for production equipment, needs for change existing program and test over again. For prepare this constraints, it needs studying an auto-configuration functions that build for both visibility and flexibility based on the 4M (Man, Machine, Material, Method) group management which is supports from WSN (Wireless Sensor Network) of the open embedded device called M2M (Machine to Machine) and major functions of middleware including point manager for real-time device communication, real-time data management, Standard API (Application Program Interface) and application template management. To be application system to RMS (Reconfigurable Manufacturing System) for rapidly response from various orders and model from motor company that is beginning to establishing the mapping of manufacturing resources of 4M using WSN.
Six Pandalid Shrimps of the Genus Plesionika (Crustacea: Decapoda: Caridea) in Korea
Jung Nyun Kim,Jung Hwa Choi,Jeong-Hoon Lee,Joo Il Kim
Animal Systematics, Evolution and Diversity , 2012, DOI: http://dx.doi.org/10.5635/ased.2012.28.2.105
Abstract: Based on samples collected from the Korean Exclusive Economic Zone (EEZ) during an investigation of fishery resources by the National Fisheries Research and Development Institute (NFRDI) from 2002 to 2010, alongside some supplemental material, six species of the genus Plesionika are identified: P. izumiae Omori, 1971, P. ortmanni Doflein, 1902, P. grandis Doflein, 1902, P. lophotes Chace, 1985, P. narval (Fabricius, 1787), and P. orientalis Chace, 1985. Of these, the last four species are new to Korean marine fauna. The distributional range of P. narval extends to the East China Sea off Jeju Island. Excluding P. izumiae and P. ortmanni, the other four species are relatively rare in the seas around Korea. They are described and illustrated with color photographs. A key to the Korean species of Plesionika is also presented.
Descriptions of Five Species of Scyllarine Lobsters (Crustacea, Decapoda, Scyllaridae) in Korea
Jung Nyun Kim,Jung Hwa Choi,Jeong-Hoon Lee,Joo Il Kim
Animal Systematics, Evolution and Diversity , 2013, DOI: http://dx.doi.org/10.5635/ased.2013.29.2.115
Abstract: Five scyllarine lobster species, belonging to the family Scyllaridae, are described from Korean waters: Chelarctus cultrifer (Ortmann, 1897), Crenarctus bicuspidatus (De Man, 1905), Galearctus kitanoviriosus (Harada, 1962), G. timidus (Holthuis, 1960), and Petrarctus brevicornis (Holthuis, 1946). Of these, three species, C. bicuspidatus, G. timidus, and P. brevicornis are new to Korean marine carcinological fauna. This report extends the known range of G. timidus to the southern coast of Korea from Taiwan in the East China Sea. Excluding C. bicuspidatus and G. kitanoviriosus, the other three species are relatively rare in Korean waters. They are described herein with color photographs, and a key to the Korean genera and species of Scyllarinae is also presented.
Reduction of Oxidative Stress Attenuates Lipoapoptosis Exacerbated by Hypoxia in Human Hepatocytes
Sang Youn Hwang,Su Jong Yu,Jeong-Hoon Lee,Hwi Young Kim,Yoon Jun Kim
International Journal of Molecular Sciences , 2015, DOI: 10.3390/ijms16023323
Abstract: Chronic intermittent hypoxia, a characteristic of obstructive sleep apnea (OSA), is associated with the progression of simple hepatic steatosis to necroinflammatory hepatitis. We determined whether inhibition of a hypoxia-induced signaling pathway could attenuate hypoxia-exacerbated lipoapoptosis in human hepatocytes. The human hepatocellular carcinoma cell line (HepG2) was used in this study. Palmitic acid (PA)-treated groups were used for two environmental conditions: Hypoxia (1% O 2) and normoxia (20% O 2). Following the treatment, the cell viability was determined by the 3,4-(5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium salt (MTS) assay, and the mechanism of lipoapoptosis was evaluated by Western blotting. Hypoxia exacerbated the suppression of hepatocyte growth induced by palmitic acid via activation of mitochondrial apoptotic pathways as a result of endoplasmic reticulum (ER) and oxidative stresses. Ammonium pyrrolidine dithiocarbamate, a scavenger of reactive oxygen species, attenuated the hypoxia-exacerbated lipoapoptosis in hepatocytes, whereas glycerol, which reduces ER stress, did not. This may have been because inhibition of oxidative stress decreases the expression of pro-apoptotic proteins, such as caspase 9 and cytochrome c. These results suggested that modulation of apoptotic signaling pathways activated by oxidative stress can aid in identifying novel therapeutic strategies for the treatment of nonalcoholic steatohepatitis (NASH) with OSA. Further in vivo studies are necessary to understand the pathophysiologic mechanism of NASH with OSA and to prove the therapeutic effect of the modulation of the signaling pathways.
Turbo Warrants under Hybrid Stochastic and Local Volatility
Min-Ku Lee,Ji-Hun Yoon,Jeong-Hoon Kim,Sun-Hwa Cho
Abstract and Applied Analysis , 2014, DOI: 10.1155/2014/407145
Abstract: This paper considers the pricing of turbo warrants under a hybrid stochastic and local volatility model. The model consists of the constant elasticity of variance model incorporated by a fast fluctuating Ornstein-Uhlenbeck process for stochastic volatility. The sensitive structure of the turbo warrant price is revealed by asymptotic analysis and numerical computation based on the observation that the elasticity of variance controls leverage effects and plays an important role in characterizing various phases of volatile markets. 1. Introduction Turbo warrants, which appeared first in Germany in late 2001, have experienced a considerable growth in Northern Europe and Hong Kong. They are special types of knockout barrier options in which the rebate is calculated as another exotic option. For one thing, this contract has a low vega so that the option price is less sensitive to the change of the implied volatility of the security market, and for another, it is highly geared owing to the possibility of knockout. Closed form expression for the price has been presented by Eriksson [1] under geometric Brownian motion (GBM) for the underlying security. It is well-known that the assumption of the GBM for the underlying security price in the Black-Scholes model [2] does not capture many empirical lines of evidence appeared in financial markets. Maybe, the two most significant shortcomings of the model's assumption lie in flat implied volatility, whereas the volatility fluctuates depending upon market conditions and the underestimation of extreme moves, yielding tail risk. So, there have been a lot of alternative underlying models developed to extend the GBM and overcome these problems. Local volatility models are one type of them, where the volatility depends on the price level of the underlying security itself. The most well-known local volatility model is the constant elasticity of variance (CEV) model in which the volatility is given by a power function of the underlying security price. It has been proposed by Cox [3] and Cox and Ross [4]. Another version of volatility models has been developed by assuming security's volatility to be a random process governed by another state variables such as the tendency of volatility to revert to some long-run mean value, the variance of the volatility process itself, and so forth. This type of models is called (pure) stochastic volatility models. The models developed by Heston [5] and Fouque et al. [6] are popular ones among others in this category. Also, there is another type of generalized models for the underlying
Pricing Arithmetic Asian Options under Hybrid Stochastic and Local Volatility
Min-Ku Lee,Jeong-Hoon Kim,Kyu-Hwan Jang
Journal of Applied Mathematics , 2014, DOI: 10.1155/2014/784386
Abstract: Recently, hybrid stochastic and local volatility models have become an industry standard for the pricing of derivatives and other problems in finance. In this study, we use a multiscale stochastic volatility model incorporated by the constant elasticity of variance to understand the price structure of continuous arithmetic average Asian options. The multiscale partial differential equation for the option price is approximated by a couple of single scale partial differential equations. In terms of the elasticity parameter governing the leverage effect, a correction to the stochastic volatility model is made for more efficient pricing and hedging of Asian options. 1. Introduction Since the well-known work of Black and Scholes [1] on the classical vanilla European option, there has been concern about the pricing of more complicated exotic options. An exotic option is a derivative which has a payoff structure more complex than commonly traded vanilla options. They are usually traded in over-the-counter market or embedded in structured products. Also, the pricing of them tends to require more complex methods than the classical Black-Scholes approach. This paper is concerned with one of the exotic options called an Asian option. This option is a path dependent option whose final payoff depends on the paths of its underlying asset. More precisely, the payoff is determined by the average value of underlying prices over some prescribed period of time. The name of “Asian” options is known to come from the fact that they were first priced in 1987 by David Spaughton and Mark Standish of Bankers Trust when they were working in Tokyo, Japan (cf. [2]). The main motivation of creating these options is that their averaging feature could reduce the risk of market manipulation of the underlying risky asset at maturity. Since Asian options reduce the volatility inherent in the option, the price of these options is usually lower than the price of classical European vanilla options. Note that there are two types of Asian options depending on the style of averaging: one is the arithmetic average Asian option and the other is the geometric average Asian option. Since there is no general analytical formula for the price of Asian option, a variety of techniques have been developed to approximate the price of this option. Subsequently, there has been quite an amount of literature devoted to studying this option. For instance, Geman and Yor [3] computed the Laplace transform of the price of continuously sampled Asian options. However, there is a problem of slow convergence for low
Protein induced by vitamin K absence or antagonist-II production is a strong predictive marker for extrahepatic metastases in early hepatocellular carcinoma: a prospective evaluation
Hyun-Mi Bae, Jeong-Hoon Lee, Jung-Hwan Yoon, Yoon Kim, Dae Heo, Hyo-Suk Lee
BMC Cancer , 2011, DOI: 10.1186/1471-2407-11-435
Abstract: Patients diagnosed with HCC without evidence of extrahepatic metastases were prospectively enrolled. We evaluated the correlation between extrahepatic metastases and pretreatment clinical variables, including serum tumor markers.A total of 354 patients were included. Seventy-six patients (21%) had extrahepatic metastases during the observation period (median, 25.3 months; range, 0.6-51.3 months). Cox regression multivariate analysis showed that serum protein induced by vitamin K absence or antagonist-II (PIVKA-II) production levels, the intrahepatic tumor stage, platelet count, and portal vein thrombosis were independent risk factors for extrahepatic metastases. Patients with a PIVKA-II production ≥ 300 mAU/mL had a 2.7-fold (95% confidence interval; 1.5-4.8; P < 0.001) and 3.7-fold (95% confidence interval; 2.0-6.6; P < 0.001) increased risk for extrahepatic metastases after adjustment for stage, platelet count, alpha-fetoprotein ≥ 400 ng/mL, and portal vein thrombosis according to the AJCC and BCLC staging systems, respectively.PIVKA-II production levels might be a good candidate predictive marker for extrahepatic HCC metastases, especially in patients with smaller and/or fewer tumors in the liver with in stages regardless of serum alpha-fetoprotein.Hepatic resection and liver transplantation are an established curative treatment for early stage HCC patients [1-3]. However, few good candidates are available for surgical resection and liver transplantation due to surgical risks associated with liver cirrhosis and the limited number of available donors, respectively. On the other hand, alternative therapeutic approaches, such as percutaneous ethanol injection (PEI) or radiofrequency ablation (RFA) for small HCCs [3,4] and transarterial chemoembolization (TACE) for multinodular hypervascular HCC, have been widely applied for the treatment of patients with HCC [5,6]. Although an increased number of therapeutic options may improve treatment results for small HCCs, a si
A Study on a Solar Simulator for Dye Sensitized Solar Cells
Kyoung-Jun Lee,Jeong-Hoon Kim,Ho-Sung Kim,Dongsul Shin,Dong-Wook Yoo,Hee-Je Kim
International Journal of Photoenergy , 2012, DOI: 10.1155/2012/834347
Abstract: Dye-sensitized solar cells (DSSC) are emerging low-cost, simple alternatives to conventional solar cells. While there has been considerable study on improving the efficiency of DSSCs, there has not been sufficient research on a photovoltaic power conditioning system adaptable to DSSCs or on a solar simulator for DSSCs. When DSSCs are commercialized in the near future, the DSSC modules must be connected to an adaptable power conditioning system in order to manage the energy produced and provide a suitable interface to the load. In the process of developing a power conditioning system, a solar simulator with the characteristics of DSSCs is essential to show the performance of the maximum power point tracking. In this paper, a virtual DSSC is designed and simulated in PSIM. Irradiation factors, temperature and shadow effects are considered in dynamic link library block in PSIM which is linked to the external C routine. A 100 W converter is built to show the performance of a DSSC as the solar simulator controlled by a digital signal processor.
PDHK-2 Deficiency Is Associated with Attenuation of Lipase-Mediated Fat Consumption for the Increased Survival of Caenorhabditis elegans Dauers
Sunhee Kim, E-Jin Shin, Jeong-Hoon Hahm, Pil-Jong Park, Ji-Eun Hwang, Young-Ki Paik
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0041755
Abstract: In Caenorhabditis elegans, slow fat consumption has been suggested to contribute to the extension of the survival rate during nutritionally adverse conditions. Here, we investigated the potential role of pyruvate dehydrogenase kinase (PDHK)-2, the C. elegans homolog of mammalian PDK, effects on fat metabolism under nutritional conditions. PDHK-2 was expressed at low levels under well-fed conditions but was highly induced during long-term starvation and in the dauer state. This increase in pdhk-2 expression was regulated by both DAF-16 and NHR-49. Dauer-specific induction of PDHK-2 was abolished upon entry into the post-dauer stage. Interestingly, in the long-term dauer state, stored fat levels were higher in daf-2(e1370);pdhk-2 double mutants than in daf-2(e1370), suggesting a positive relationship between PDHK-2 activity and fat consumption. PDHK-2 deficiency has been shown to lead to greater preservation of residual fats, which would be predicted to contribute to survival during the dauer state. A test of this prediction showed that the survival rates of daf-2(e1370);pdhk-2(tm3075) and daf-2(e1370);pdhk-2(tm3086) double mutants were higher than that of daf-2(e1370), suggesting that loss of either the ATP-binding domain (tm3075) or branched chain keto-acid dehydrogenase kinase domain (tm3086) of PDHK-2 leads to reduced fat consumption and thus favors increased dauer survival. This attenuated fat consumption in the long-term dauer state of C. elegans daf-2 (e1370);pdhk-2 mutants was associated with concomitant down-regulation of the lipases ATGL (adipose triglyceride lipase), HSL (hormone-sensitive lipase), and C07E3.9 (phospholipase). In contrast, PDHK-2 overexpression in wild-type starved worms induced lipase expression and promoted abnormal dauer formation. Thus, we propose that PDHK-2 serves as a molecular bridge, connecting fat metabolism and survival under nutritionally adverse conditions in C. elegans.
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