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The Great Lapse: Climate Change, Water Resources and Economic Risks in the Great Lakes  [PDF]
Jenny Kehl
Journal of Water Resource and Protection (JWARP) , 2018, DOI: 10.4236/jwarp.2018.1011065
Abstract: The striking vastness of the world’s largest surface freshwater resource, the Laurentian Great Lakes, has generated the fallacy that they are not highly vulnerable to climate change. This fallacy has created a great lapse in our research and understanding of the effects of climate change on the Great Lakes, which are approaching critical environmental thresholds and jeopardizing ecosystem services. This article takes the novel approach of correcting the disconnect between the perception of vastness and the reality of vulnerability to climate change in the Great Lakes, and takes an additional novel step to link the water risks with the economic risks. The primary purpose is to demonstrate the interdependence of the freshwater ecosystem services affected by climate change with the economies that are highly dependent on those freshwater services in the Great Lakes region. Although many believe that environmental science or ethical arguments should be sufficient to warrant action on climate change, evidence shows that policy-makers are not compelled to generate advances unless there are strong economic components. This article highlights the leading edge of climate science for the Great Lakes, having conducted 32 in depth interviews with experts in microbiology, ecology, and limnology, among others, but it also adds substantively to previous work by providing economic evidence of water risks in the agricultural sector and energy sector, which constitute over $6 trillion in value and jobs that are specifically dependent on lakes waters. The article concludes by articulating three specific conclusions: the economic viability of the agricultural sector and the energy sector are jeopardized by loss of federal funding for climate change adaptation in the water sector; the existing policies such as between sectors such as the Farm Bill and Energy Future Bill are mal-aligned and should be aligned with the water sector; and negative environmental externalities including factors that exacerbate climate change should be incorporated into the true cost of water so we can more accurately conduct ecosystem valuation and, thus, address the true economic and environmental cost of climate change on the Great Lakes and our greatest water resources. This paper has not previously been published.
A publicidade e o mestre do gozo
Maria Rita Kehl
Comunica??o, Mídia e Consumo , 2004,
Abstract: O mundo capitalista, em sua fase consumista, é organizado pelo fetiche. O que já estava em Marx, com o conceito de fetiche da mercadoria, passa a incluir a dimens o freudiana do fetiche, que diz respeito às modalidades perversas de gozo. A publicidade acrescenta às mercadorias o fetiche da imagem e da marca, que se oferecem à identifica o de todos, independentemente do poder aquisitivo. Neste mundo, os publicitários seriam os mestres do gozo, cujo poder se assemelha ao fascínio que os perversos exercem sobre os neuróticos comuns. Abstrat: The capitalistic world, in its consumist phase, is organized by the fetish. What was already in Marx, as the concept of merchandise fetish, now includes the Freudian dimension of fetish that says respect to the perverse modalities of pleasure. Publicity adds to merchandise the fetish of image and brand, which are offered to the identification of all, independent of purchasing power. In this world, publicists would be the masters of pleasure whose power resembles that one that the perverse exert on the common neurotics. Palavras-chave: Publicidade, pervers o, gozo, Lei. Key-words: Publicity, perversion, pleasure, Law.
Short Report—The MDT Speed Date  [PDF]
Jenny Blythe
Creative Education (CE) , 2018, DOI: 10.4236/ce.2018.98093
Abstract: The importance of introducing both interprofessional education (IPE) and familiarity with the wider multidisciplinary team (MDT) roles cannot be underestimated in the undergraduate medical curriculum. This short report outlines an innovative method of teaching medical students about the role of the MDT in holistic patient management by way of a simulation “speed-date” and MDT meeting.
FEM-Based Method for the Simulation of Dielectric Waveguide Grating Biosensors
Thomas Guillod;Florian Kehl;Christian V. Hafner
PIER , 2013, DOI: 10.2528/PIER13020502
Abstract: Label-free optical biosensors are important tools to study the kinetics, interaction and presence of (bio)chemical compounds in various fields such as biotechnology, pharma, diagnostics as well as environmental and food quality monitoring. Systems based on planar optical waveguides with input/output grating couplers are of interest as they offer multiple tuning parameters for the chip design and their high sensitivity. In the present paper, an algorithm based on the Finite-Elements Method (FEM) is proposed for finding the chip response and optimizing the sensitivity of the sensor system. Total field and scattered field coupled with the Transmission Line Transfer Matrix Method (TLTMM) are compared for the FEM. Unlike some widely used approximations, the impact of the grating depth, shape, duty cycle as well as losses and surface roughness are taken into account. Another advantage of the presented method is the possibility to implement a large part of the algorithm with commercially available FEM solver. Several practical situations are treated proving the validity of the approach against the Local Interference Method (LIME). The waveguide losses appear to be a decisive parameter for the chip design.
Non-Simian Foamy Viruses: Molecular Virology, Tropism and Prevalence and Zoonotic/Interspecies Transmission
Timo Kehl,Juan Tan,Magdalena Materniak
Viruses , 2013, DOI: 10.3390/v5092169
Abstract: Within the field of retrovirus, our knowledge of foamy viruses (FV) is still limited. Their unique replication strategy and mechanism of viral persistency needs further research to gain understanding of the virus-host interactions, especially in the light of the recent findings suggesting their ancient origin and long co-evolution with their nonhuman hosts. Unquestionably, the most studied member is the primate/prototype foamy virus (PFV) which was originally isolated from a human (designated as human foamy virus, HFV), but later identified as chimpanzee origin; phylogenetic analysis clearly places it among other Old World primates. Additionally, the study of non-simian animal FVs can contribute to a deeper understanding of FV-host interactions and development of other animal models. The review aims at highlighting areas of special interest regarding the structure, biology, virus-host interactions and interspecies transmission potential of primate as well as non-primate foamy viruses for gaining new insights into FV biology.
Is the Distribution of Microorganisms and Peritonitis Affected by Seasonality in Peritoneal Dialysis?  [PDF]
Ana Elizabeth Figueiredo, Ana Carolina Gon?alves Kehl, Stephanie Thomaz Bottin, Wilem Gomes Daminelli
Open Journal of Nephrology (OJNeph) , 2014, DOI: 10.4236/ojneph.2014.44021
Introduction: Peritonitis continues to be the main complication for patients on peritoneal dialysis (PD). Objective: To determine the frequency of peritonitis according to the disease-causing microorganism and its distribution throughout the year, linking to seasonality. Methods: A retrospective study conducted in the Dialysis Unit of the Hospital São Lucas, PUCRS (HSL-PUCRS). Patients undergoing PD between January 1984 and September 2013 were included. Descriptive statistics were used and Fisher’s exact test with Monte Carlo simulation for comparison between the categorical variables. Results: Of 415 evaluated patients, 66% had at least one episode of peritonitis with an incidence rate of 0.68 episode/year. There were 601 peritonitis episodes in total. The most common microorganism was coagulase-negative Staphylococcus (26.6%, n = 160), followed by Staphylococcus aureus (16.3%, n = 98), with 16.3% of the sample being negative culture. Most episodes occurred in the months of January (10.3%, n = 62) and May (10.1%, n = 61), while June had the lowest occurrence (5.2%, n = 31). The number of episodes observed in January and May were significantly higher when compared to June (p < 0.001). No significant differences were found for the remaining months. There was no association between the microorganisms and months of the year (p = 0.841). Conclusion: The rate of peritonitis is in line with that recommended by the International Society for Peritoneal Dialysis. The distribution of peritonitis-causing germs over the months of the year would seem to be random.
NEFI: Network Extraction From Images
Michael Dirnberger,Adrian Neumann,Tim Kehl
Computer Science , 2015,
Abstract: Networks and network-like structures are amongst the central building blocks of many technological and biological systems. Given a mathematical graph representation of a network, methods from graph theory enable a precise investigation of its properties. Software for the analysis of graphs is widely available and has been applied to graphs describing large scale networks such as social networks, protein-interaction networks, etc. In these applications, graph acquisition, i.e., the extraction of a mathematical graph from a network, is relatively simple. However, for many network-like structures, e.g. leaf venations, slime molds and mud cracks, data collection relies on images where graph extraction requires domain-specific solutions or even manual. Here we introduce Network Extraction From Images, NEFI, a software tool that automatically extracts accurate graphs from images of a wide range of networks originating in various domains. While there is previous work on graph extraction from images, theoretical results are fully accessible only to an expert audience and ready-to-use implementations for non-experts are rarely available or insufficiently documented. NEFI provides a novel platform allowing practitioners from many disciplines to easily extract graph representations from images by supplying flexible tools from image processing, computer vision and graph theory bundled in a convenient package. Thus, NEFI constitutes a scalable alternative to tedious and error-prone manual graph extraction and special purpose tools. We anticipate NEFI to enable the collection of larger datasets by reducing the time spent on graph extraction. The analysis of these new datasets may open up the possibility to gain new insights into the structure and function of various types of networks. NEFI is open source and available http://nefi.mpi-inf.mpg.de.
Empirical Verification of Swanson’s Caring Processes Found in Nursing Actions: Systematic Review  [PDF]
Mary Kalfoss, Jenny Owe
Open Journal of Nursing (OJN) , 2015, DOI: 10.4236/ojn.2015.511104
Abstract: Caring has long been recognized as central to nursing and is increasingly posited as a core concept although developing a theoretical description of caring which is adequate in the 21st. century continues to be a difficult task for nursing scholars. Consequently, verifying existing theoretical structures of caring remains an ongoing challenge. The aim of this article is to provide empirical verification of the caring processes of “knowing,” “being with,” “doing for,” “enabling” and “maintaining belief” from Swanson’s Middle Range Caring Theory based on the categorization of nursing actions from a systematic literature review on care. Methods: A systematic literature review was conducted in the fields of nursing sciences, medicine and psychology. Purposeful sampling was carried out covering a period from 2003-2013. The final sample included 25 articles. Results: Major themes of nursing actions included “knowing” which consisted of centering, nurturing, informed understanding, assessment skills, communication and respect for individual differences. “Being with” was characterized by intimate relationship, connecting, presencing, emotional adaptability awareness of self/other and decentering. “Doing for” included competence, knowledge, professional/technical skills, helping actions, anticipatory, multidisciplinary and preserving dignity. “Enabling” was characterized by self care, commitment, complexity of care, appropriate communication, information/education, sharing power, enabling choice and ongoing validation. Finally, “maintaining belief” was characterized by spiritual being, humanistic view, harmonious balance, hope, love, and compassion, meaning, and religious and spiritual orientation. Conclusion: Empirical verification was shown for the caring processes described in Swanson’s Caring Theory grounded in concrete nursing actions.
Design of a Label-Free, Distributed Bragg Grating Resonator Based Dielectric Waveguide Biosensor
Florian Kehl,David Bischof,Markus Michler,Mirjad Keka,Ross Stanley
Photonics , 2015, DOI: 10.3390/photonics2010124
Abstract: In this work, we present a resonant, dielectric waveguide device based on distributed Bragg gratings for label-free biosensing applications. The refractive index sensitive optical transducer aims at improving the performance of planar waveguide grating sensor systems with limited Q-factor and dynamic range by combing the advantages of resonant cavities, such as a multitude of resonance peaks with high finesse, with the manageable complexity of waveguide grating couplers. The general sensor concept is introduced and supported by theoretical considerations as well as numerical simulations based on Coupled Mode Theory. In contrast to a single Bragg grating reflector, the presented Fabry-Pérot type distributed Bragg resonator exhibits an extended measurement range as well as relaxed fabrication tolerances. The resulting, relatively simple sensor structure can be fabricated with standard lithographic means and is independent of expensive light-sources and/or detectors, making an affordable but sensitive device, potentially suitable for point-of-care applications.
Pathogenesis of cardiac graft failure in children  [PDF]
Jenny Lin, Bahig M. Shehata
Open Journal of Pediatrics (OJPed) , 2012, DOI: 10.4236/ojped.2012.24051
Abstract: For many critical cardiac conditions such as cardio-myopathy, congenital heart defects, or arrhythmogenic disorders, cardiac transplantation is often an accepted treatment with optimistic one- and five-year survival rates of 90% and 75% in the pediatric patient population, respectively. However, poor long-term survival is a cause for concern, with cardiac graft failure being the leading cause in late mortality transplant recipients. Cardiac graft failure occurs through several mechanisms. However, the most common causes include cardiac allograft vasculopathy, myocardial fibrosis, and fibrofatty changes. Risk factors exacerbate these mechanisms through rejection, immunosuppressive drug side effects, hypertension, diabetes mellitus, renal dysfunction, and viral infection to increase the chance of cardiac graft failure. Changes in expression levels of various genes offer diagnostic potential for the future of cardiac transplantation. Through a comprehensive review of how multiple factors can lead a cardiac graft into failure, we hope to contribute to the longevity of cardiac grafts and pediatric heart transplant recipients.
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