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Search Results: 1 - 10 of 74014 matches for " Jean Carl Silva "
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Tratamento do diabetes mellitus gestacional com glibenclamida: fatores de sucesso e resultados perinatais
Silva, Jean Carl;Heinen, Amanda;Scheidt, Mariana Benedet;Marcondes, Marina Abreu de Oliveira;Bertini, Anna Maria;
Revista Brasileira de Ginecologia e Obstetrícia , 2007, DOI: 10.1590/S0100-72032007001100002
Abstract: purpose: to identify the factors related to successful gestational diabetes mellitus (gdm) management with glyburide and to evaluate perinatal outcomes. methods: prospective longitudinal study including 50 pregnant women with gdm who required complementary treatment to diet and physical activity, whose fetus presented normal abdominal circumference (ac) to ultrasound (pct<75). study period was august 2005 to july 2006. ultrasonography was carried out monthly. glyburide was used until delivery, as long as glucose control was obtained and fetal ac was normal, being thus considered therapeutically successful. in case there was no glucose control or alteration in ac, management was switched to insulin therapy, being thus considered therapeutically unsuccessful. pregnant women were divided into two groups: one therapeutically successful (n=29) and another therapeutically unsuccessful (n=21). the results evaluated were: therapeutic success, maternal characteristics and perinatal outcome. results: fifty-eight percent of the cases were successfully managed with glyburide. no difference was found (p>0.05) in either group, with regards to maternal age, glucose values at ogtt75g, maternal body mass index (bmi), number of pre-natal consultations, number of previous pregnancies. according to the logistic model of regression used, therapeutically successful pregnant patients had had a later diagnosis (p=0.02) and lower weight gain during gestation (p<0.01). perinatal outcome did not differ in either group. conclusions: patients with later diagnosis and lower weight gain are more likely to have successful gdm management with glyburide. unsuccessful management with glyburide did not alter the perinatal outcome.
Resultados preliminares do uso de anti-hiperglicemiantes orais no diabete melito gestacional
Silva, Jean Carl;Taborda, Wladimir;Becker, Felipe;Aquim, Gabriela;Viese, Juliana;Bertini, Anna Maria;
Revista Brasileira de Ginecologia e Obstetrícia , 2005, DOI: 10.1590/S0100-72032005000800005
Abstract: purpose: to compare the effectiveness of glibenclamide and acarbose with that of insulin for the treatment of gestational diabetes mellitus (gdm), in regard to maternal glucose levels, newborn (nb) weight and neonatal hypoglycemia. methods: an open, randomized prospective study was carried out. fifty-seven patients diagnosed with gdm were included. these patients required dietary control and additional therapy. pregnant women were randomly alloted to one of three groups with different therapies: a control group making use of insulin therapy, a study group making use of glibenclamide and a study group making use of acarbose. the study took seven months (from october 1st 2003 to may 1st 2004). assessed outcomes were maternal glucose levels in the prenatal period, the need for replacing therapy to achieve glucose level control, nb weight and neonatal hypoglycemia. statistical analysis was determined by anova with the level of significance set at 5%. results: maternal characteristics were similar in all the three groups. glucose level control was not obtained in three of the patients who used glibenclamide (15%) and in seven (38.8%) of the patients who used acarbose. regarding fasting and postprandial glucose level rates and average nb weight no difference between the three groups was observed. no statistical difference was found for fasting or postprandial glucose levels and average nb weight in any of the three groups. the rate of large for gestational age fetuses was 5.2, 31.5 and 11.1% for the groups treated with insulin, glibenclamide and acarbose, respectively. neonatal hypoglycemia was observed in six nb. four of these were from the glibenclamide group (21.0%). conclusions: glibenclamide was more effective for glucose level control than acarbose but neither were more efficient than insulin. nb children whose mothers had been alloted to the glibenclamide group showed a higher rate of macrosomia and neonatal hypoglycemia when compared to those newborns whose mother
O efeito em curto prazo do bypass gástrico sobre pacientes obesos diabéticos Short-term effect of gastric bypass in obese diabetic patients
Aluisio Stoll,Jean Carl Silva,Luiz Carlos Von Bahten,Giovana Gugelmin
Revista do Colégio Brasileiro de Cirurgi?es , 2013,
Abstract: OBJETIVO: estudar o efeito do bypass gástrico sobre a glicemia e o uso de medica o antidiabética em pacientes obesos portadores de diabetes. MéTODOS: estudo de coorte retrospectivo com 44 pacientes obesos portadores de DM2, provenientes de 469 pacientes submetidos ao bypass gástrico no período de dezembro de 2001 a mar o de 2009. Os desfechos primários avaliados foram: glicemia em jejum e a necessidade de medica o antidiabética. RESULTADOS: a popula o foi composta de dez (22,7%) homens e 34 (77,3%) mulheres, com média de idade de 45,3 (±8,23) anos e índice de massa corporal de 40,9 (±5,03) kg/m2. O tempo médio de evolu o do DM2 foi 63,6 (±60,9) meses. Dos 40 pacientes que utilizavam medica o para controle do DM2, 20 (50%) tiveram sua medica o suspensa na alta hospitalar e 13 (32,5%) até nove meses depois. Em uma paciente n o foi possível avaliar o uso de medica o, sendo essa a única exclus o. A insulina foi suspensa nos dez (100%) pacientes que a utilizavam, sendo seis (60%) na alta hospitalar. Houve redu o (P<0,05) da glicemia em jejum, em todo o período estudado, em compara o com o valor pré-operatório, e foram atingidos valores inferiores a 100mg/dl no período de sete a nove meses. CONCLUS O: Pacientes obesos portadores de DM2, submetidos ao bypass gástrico, apresentaram melhora do controle glicêmico e redu o do uso de hipoglicemiantes em curto prazo. OBJECTIVE: To study the effect of gastric bypass on blood glucose levels and the use of antidiabetic medication in obese patients with diabetes. METHODS: We carried out a retrospective cohort study with 44 obese patients with DM2, from 469 patients undergoing gastric bypass from December 2001 to March 2009. The primary endpoints evaluated were fasting glucose and the need for antidiabetic medication. RESULTS: The study population consisted of ten (22.7%) men and 34 (77.3%) women, with a mean age of 45.3 (±8.23) years and a body mass index of 40.9 (±5.03) kg/m2. The average time to progression of DM2 was 63.6 (±60.9) months. Of the 40 patients who used medication to control type 2 diabetes, 20 (50%) had their medication discontinued at discharge and 13 (32.5%), until nine months later. In one patient it was not possible to evaluate the use of medication, this being the only exception. Insulin was suspended in ten (100%) patients who used it, six (60%) at discharge. Fasting plasma glucose levels decreased throughout the study period (p <0.05) when compared with preoperative values, and values below 100mg/dl were achieved within seven to nine months. CONCLUSION: Obese patients with DM2 undergoing
Fatores relacionados à presen?a de recém-nascidos grandes para a idade gestacional em gestantes com diabetes mellitus gestacional
Silva, Jean Carl;Bertini, Anna Maria;Ribeiro, Thaís Engel;Carvalho, Leonardo Souza de;Melo, Muriel Matias;Barreto Neto, Lauro;
Revista Brasileira de Ginecologia e Obstetrícia , 2009, DOI: 10.1590/S0100-72032009000100002
Abstract: purpose: to evaluate factors related to the presence of neonatal macrosomia in pregnant women with gestational diabetes mellitus. methods: 157 pregnant women presenting gestational diabetes mellitus in follow-up were retrospectively selected from january 2004 to july 2006. this group has been divided into two subgroups: one with newborns with weight in accordance with the gestational age (n=136) and another with macrosomic newborns (n=21). maternal characteristics have been compared between the groups. the t-student test was used for the analysis of equality hypothesis between the averages of the two groups, and chi-square test, to check the groups' homogeneity concerning ratios. results: the groups did not show any significant difference concerning the gestational age, body mass index, weight gain along the gestation, number of previous pregnancies, fast glycemia in the oral glucose tolerance test after the ingestion of 75 g (totg 75 g), gestational age at delivery, glycemic values during the treatment, and the type of treatment used (p>0.05). in the group with neonatal macrosomia, there was a higher two-hour-glycemia in the totg 75 g (p=0.02), higher gestational age at the treatment onset (p=0.02), and a lower number of appointments at the health service (p<0.01). when adjusted to a logistic regression model, the most important factor (p<0.01) found to predict neonatal macrosomia was the two-hour-glycemia in the totg 75 g. conclusions: the factors more frequently related to neonatal macrosomia were late treatment onset and, consequently, lower number of appointments and chiefly, high two-hour-glycemia in the totg 75 g.
Non-Hermitian extension of gauge theories and implications for neutrino physics
Jean Alexandre,Carl M. Bender,Peter Millington
Physics , 2015, DOI: 10.1007/JHEP11(2015)111
Abstract: An extension of QED is considered in which the Dirac fermion has both Hermitian and anti-Hermitian mass terms, as well as both vector and axial-vector couplings to the gauge field. Gauge invariance is restored when the Hermitian and anti-Hermitian masses are of equal magnitude, and the theory reduces to that of a single massless Weyl fermion. An analogous non-Hermitian Yukawa theory is considered, and it is shown that this model can explain the smallness of the light-neutrino masses and provide an additional source of leptonic CP violation.
Redes neurais artificiais na classifica??o de frutos: cenário bidimensional
Ramos, Jean Paulo Silva;
Ciência e Agrotecnologia , 2003, DOI: 10.1590/S1413-70542003000200015
Abstract: agriculture is one of the economic activities that more require the presence human being in the decision taking. innumerable are the processes that require some type of human being interference in the conclusion of the processes. fruit sorting depends on human or artificial pattern recognition according to some pre defined categories. once a fruit pattern is under classification, this one must be compared to some other ones stored. after that comparison it can be classified. most sorting fruits jobs are human basis classification. this paper shows that using neural networks is possible to develop capable models of storing fruit pattern vectors. given any fruit pattern vector to the model it can classify to the closest fruit pattern vector stored. the number of patterns were incremented and presented to the neural networks, classifying the presented fruits and proved the scalability of number of vector components used in fruit pattern vectors stored in the model. this work was developed in the agricultural machinery department of the agricultural faculty in state university of campinas, the neural networks stored fruit pattern vectors such as weight, diameter. these vectors components associated itself interacted determining an output pattern vector classifying according to the stored fruit vector patterns. a multi layer perceptron network with backpropagation algorithm was used, storing the relationship between input fruit pattern vectors and output classification class vectors. the neural network was trained and tested presenting the desired results, it can be used as a tool for future fruit classification processes.
Book Review – Negócios com Jap o, Coréia do Sul e China: Economia, Gest o e Rela es com o Brasil.
Jean Barros e Silva
Revista de Administra??o Contemporanea , 2009,
Seuils d'instabilité d'un instrument de musique à anche simple : approche modale
Fabrice Silva,Jean Kergomard
Physics , 2008,
Abstract: Many musical instruments, as for example woodwind instruments, flute or violins, are self-sustained oscillating systems, i.e. musician enacts as a continuous energy source to drive an oscillation in the passive resonator, the body of the instrument, by means of a nonlinear coupling. For single reed instruments like clarinet, there exists a minimal value of mouth pressure beyond which sound can appear. This paper deals with the analysis of this oscillation threshold, calculated using a modal decomposition of the resonator, in order to have a better comprehension of how reed characteristics, such as its strength and its damping, may influence the attack transient of notes.
Homogenization of Degenerate Porous Medium Type Equations in Ergodic Algebras
Hermano Frid,Jean Silva
Mathematics , 2013,
Abstract: We consider the homogenization problem for general porous medium type equations of the form $u_t=\D f(x,\frac{x}{\ve}, u)$. The pressure function $f(x,y,\cdot)$ may be of two different types. In the type~1 case, $f(x,y,\cdot)$ is a general strictly increasing function; this is a mildly degenerate case. In the type~2 case, $f(x,y,\cdot)$ has the form $h(x,y)F(u)+S(x,y)$, where $F(u)$ is just a nondecreasing function; this is a strongly degenerate case. We address the initial-boundary value problem for a general, bounded or unbounded, domain $\Om$, with null (or, more generally, steady) pressure condition on the boundary. The homogenization is carried out in the general context of ergodic algebras. As far as the authors know, homogenization of such degenerate quasilinear parabolic equations is addressed here for the first time. We also review the existence and stability theory for such equations and establish new results needed for the homogenization analysis. Further, we include some new results on algebras with mean value, specially a new criterion establishing the null measure of level sets of elements of the algebra, which is useful in connection with the homogenization of porous medium type equations in the type~2 case.
Massive bleeding in polytrauma: how can we make progress?
Jean-Louis Vincent, Richard Dutton, Michael Parr, Carl Hauser
Critical Care , 2011, DOI: 10.1186/cc10438
Abstract: Recombinant human factor VIIa (rFVIIa) is often used off-label in massively bleeding patients. A recent review of use in the USA [1] and a meta-analysis of studies for nonapproved indications [2] document the frequent use of rFVIIa in a variety of clinical conditions characterized by a real risk of death or major morbidity from exsanguination.The literature demonstrates an association between use of rFVIIa and increased risk of arterial thromboembolic complications [3]. This increased risk is, of course, a predictable side effect of a procoagulant drug, and can actually be regarded as proof of its physiologic effect. These recent studies have raised doubts about the advisability of giving this product to massively bleeding patients, and have prompted some hospitals to ban or restrict the use of the drug in hemorrhaging patients. Yet the efficacy of rFVIIa as a hemostatic agent is actually well established. Perhaps the numerous case reports on the cessation of bleeding will not be entirely convincing to all defenders of evidence-based medicine, but the results from prospective randomized, placebo-controlled trials should be.Two double-blinded randomized, placebo-controlled trials have convincingly demonstrated that administration of rFVIIa in massive bleeding can reduce the need for blood transfusions [4,5]. In the first trial, red blood cell transfusion was significantly reduced in patients with blunt trauma. Moreover, just 14% of rFVIIa-treated blunt trauma patients received massive transfusions compared with 33% of placebo-treated patients (P = 0.03); in penetrating trauma, 19% of the placebo-treated patients received massive transfusions compared with only 7% of the treated group (P = 0.08). In the second trial, which was conducted to examine the 30-day mortality of patients receiving rFVIIa, the number of units of red blood cells administered to blunt trauma patients (the majority of patients studied) was significantly less in rFVIIa-treated patients than in pla
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