oalib

Publish in OALib Journal

ISSN: 2333-9721

APC: Only $99

Submit

Any time

2019 ( 1 )

2018 ( 17 )

2017 ( 14 )

2016 ( 42 )

Custom range...

Search Results: 1 - 10 of 5593 matches for " Jay Patel "
All listed articles are free for downloading (OA Articles)
Page 1 /5593
Display every page Item
Histopathologic Review of Previously Negative Prostatic Core Needle Biopsies Following a New Diagnosis of Adenocarcinoma of the Prostate by Core Needle Biopsies: Implications for Quality Assurance Programs
Jay Patel and Lester J. Layfield
Clinical Medicine Insights: Pathology , 2012,
Abstract: Programs for quality assurance are increasingly important in surgical pathology. Many quality assurance (QA) techniques for surgical pathology were adopted from procedures introduced in cytopathology. Surgical pathology specimens have diminished in size such that the majority of diagnostic biopsies of prostatic lesions are now core needle biopsies. These specimens raise issues similar to those of cytology specimens, including concerns regarding adequacy and the representative nature of the biopsy. Due to sample size, some neoplasms may not be diagnosed on initial biopsy, raising concerns regarding false negative results. Cytopathologists have instituted QA procedures including review of all previously negative slides received within five years prior to the new diagnosis of high grade squamous intraepithelial lesion or gynecologic malignancy. No such requirement exists in surgical pathology for review of core biopsies. The Department of Pathology at the University of Utah instituted a QA policy requiring review of prior negative prostatic needle biopsies following a new diagnosis of prostatic adenocarcinoma. We reviewed five years of QA records of prostate needle biopsy review. During this time, nine hundred and fifty-eight core biopsy sets were performed. Two hundred and ninety-five of these contained at least one biopsy with a diagnosis of adenocarcinoma. Two hundred and eight patients had a prior set of prostatic needle biopsies with a diagnosis of adenocarcinoma. The remaining 87 had prior biopsies with either a diagnosis of prostatic intraepithelial neoplasia (23), small atypical acinar proliferation (21) or no evidence of malignancy (43). QA review of these 87 cases revealed two biopsies which revealed foci of adenocarcinoma. Both had been initially diagnosed as no evidence of malignancy. The false negative rate for core biopsy was 0.68%. In an additional twenty-one cases, microscopic foci of atypical small acinar proliferations were found in core biopsies antedating the positive core biopsy (7.1%).
Development and Validation of Dual Wavelength Spectrophotometric Method for Simultaneous Estimation of Rosuvastatin and Diltiazem in Combined Dosage Form
Bharatkumar Ganeshbhai Chaudhari,Jay Patel
International Journal For Pharmaceutical Research Scholars , 2012,
Abstract: A simple and economical dual wavelength spectrophotometric method has been developed for the simultaneous estimation of rosuvastatin and diltiazem in their combined dosage forms. The method was based on property of addivity of absorbances. At 295.6 rosuvastatin showed absorbance but diltiazem showed zero absorbance. The two wavelengths on rosuvastatin curve were found out where it showed same absorbance, which were 227 and 247.4 nm. Diltiazem showed adequate absorbances at these wavelengths. The method involved solving of an equation based on measurement of absorbances at three wavelengths 295.6, 227, and 247.4 nm. The proposed method was found to be simple, economical, accurate, and reproducible for routine analysis of both drugs in tablet dosage forms.
Development and Validation of First Derivative Method for Simultaneous Estimation of Rosuvastatin and Diltiazem in Combined Dosage Form
Bharatkumar Ganeshbhai Chaudhari,Jay Patel
International Journal For Pharmaceutical Research Scholars , 2012,
Abstract: A simple and economical first derivative spectrophotometric method has been developed for the simultaneous estimation of rosuvastatin and diltiazem in their combined dosage forms. The method involved determination of Zero Crossing points (ZCP) in their respective derivative spectra. By scanning first derivative spectra of rosuvastatin and diltiazem, ZCP for rosuvastatin was found to be at 240 nm and for diltiazem at 236.4 nm. For rosuvastatin 236.4 nm and for diltiazem 240 nm was chosen as an analytical wavelength. The method involved solving of an equation based on measurement of absorbances at wavelengths 240 and 236.4 nm. The proposed method was found to be simple, economical, accurate, and reproducible for routine analysis of both drugs in tablet dosage form.
Histopathologic Review of Previously Negative Prostatic Core Needle Biopsies Following a New Diagnosis of Adenocarcinoma of the Prostate by Core Needle Biopsies: Implications for Quality Assurance Programs
Jay Patel,Lester J. Layfield
Clinical Medicine : Pathology , 2008,
Abstract: Programs for quality assurance are increasingly important in surgical pathology. Many quality assurance (QA) techniques for surgical pathology were adopted from procedures introduced in cytopathology. Surgical pathology specimens have diminished in size such that the majority of diagnostic biopsies of prostatic lesions are now core needle biopsies. These specimens raise issues similar to those of cytology specimens, including concerns regarding adequacy and the representative nature of the biopsy. Due to sample size, some neoplasms may not be diagnosed on initial biopsy, raising concerns regarding false negative results. Cytopathologists have instituted QA procedures including review of all previously negative slides received within five years prior to the new diagnosis of high grade squamous intraepithelial lesion or gynecologic malignancy. No such requirement exists in surgical pathology for review of core biopsies. The Department of Pathology at the University of Utah instituted a QA policy requiring review of prior negative prostatic needle biopsies following a new diagnosis of prostatic adenocarcinoma. We reviewed five years of QA records of prostate needle biopsy review. During this time, nine hundred and fifty-eight core biopsy sets were performed. Two hundred and ninety-five of these contained at least one biopsy with a diagnosis of adenocarcinoma. Two hundred and eight patients had a prior set of prostatic needle biopsies with a diagnosis of adenocarcinoma. The remaining 87 had prior biopsies with either a diagnosis of prostatic intraepithelial neoplasia (23), small atypical acinar proliferation (21) or no evidence of malignancy (43). QA review of these 87 cases revealed two biopsies which revealed foci of adenocarcinoma. Both had been initially diagnosed as no evidence of malignancy. The false negative rate for core biopsy was 0.68%. In an additional twenty-one cases, microscopic foci of atypical small acinar proliferations were found in core biopsies antedating the positive core biopsy (7.1%).
Design & Simulation Of Photovoltaic System Using Incremental Mppt Algorithum
JAY PATEL,VISHAL SHETH,GAURANG SHARMA
International Journal of Advanced Research in Electrical, Electronics and Instrumentation Engineering , 2013,
Abstract: This paper presents the design and simulation of a photovoltaic system using incremental conduction maximum power point tracking (MPPT) algorithm with boost converter . The current-voltage (I-V) & power-voltage (P-V) characteristics are obtained for solar module . The MPPT algorithm, which is based on the incremental conduction method, is also described
Secondary Knee Osteoarthritis due to Neurofibromatosis Type 1 Treated with above the Knee Amputation: A Case Report
Jay Patel,Jeffrey Whiting,Daniel Jones
Case Reports in Orthopedics , 2013, DOI: 10.1155/2013/782106
Abstract: Background. Neurofibromatosis Type 1 (NF-1) has a variety of associated orthopaedic manifestations that have been previously reported. We report a case of severe, grade 4 knee osteoarthritis (OA) with recurrent subluxation and joint laxity due to multiple extra-articular neurofibromas ultimately treated with Above the Knee Amputation (AKA). Case Description. A 39-year-old man presented with multiple neurofibromas and lymphedema leading to degenerative changes of the knee. Conservative treatment failed due to the severity of the knee degeneration and patient discomfort. Likewise, arthroplasty was not possible due to poor bone quality and joint instability. Therefore, AKA was selected to relieve symptoms and provide functional improvement. six months after the procedure the patient has increased functional capacity for ambulation and activities of daily living, as well as significant decrease in pain and discomfort. Clinical Relevance. Extra-articular neurofibromas causing severe secondary OA in relatively young patients can be functionally improved with AKA and prosthetic device use. 1. Introduction Neurofibromas are defined as benign peripheral nerve sheath neoplasms comprising of a variety of cell types. They are ill defined and commonly involve nerve fascicles and surrounding soft tissues. This involvement of soft tissues can lead to deformity of associated joints, which can cause valgus and varus laxity, as well as joint capsule compromise. These factors can all predispose a susceptible individual to recurrent subluxation [1]. Recurrent subluxation can lead to secondary OA in this patient population. Surgical approach, soft tissue quality, and joint stability were factors that led to the ultimate, consensual decision of proceeding with an AKA in this particular patient. This paper aims to demonstrate the need for recognition of the long-term musculoskeletal effects of NF-1, as well as describing the surgical decisions and methods taken in regards to a particularly young man with debilitating OA and functional impairment. 2. Case Report A 39-year-old African American male patient with NF-1 presented to the Orthopaedics Department of Saint Louis University with the chief complaint of a 30-year history of left knee instability. He was diagnosed with NF-1 after minor trauma resulted in left knee edema at age 9 and subsequent testing revealed NF-1. As he grew, this swelling also increased. He had progressive difficulty walking, only ambulating one block without aid. He could neither run nor squat. His leg was very uncomfortable and painful, and it
Evidence for First Order Cubic Paraelectric to Rhombohedral Ferroelectric Phase Transition in 0.8BiFeO3-0.2Pb(Fe1/2Nb1/2)O3
Jay Prakash Patel,Anar Singh,Dhananjai Pandey
Physics , 2009,
Abstract: The current controversies about the existence of an intermediate 'beta' phase of BiFeO_3 and the high temperature paraelectric 'gamma' phase are resolved by studying the sequence of ferroic transitions in 0.8BiFeO_3-0.2Pb(Fe_1/2Nb_1/2)O_3 (BF-0.2PFN) with lowered transition temperature. It is shown that the room temperature ferroelectric phase of 0.8BF-0.2PFN in the R3c space group transforms to the paraelectric/paraelastic cubic (Pm-3m) phase directly without any intermediate 'beta' phase reported in the literature. This transition is of first order type as confirmed by the coexistence of R3c and Pm-3m phases over a 100K range and a discontinuous change in the unit cell volume.
Review on Formability of Tailor-Welded Blanks
B.C. Patel,Jay Shah,Harindra Shah
International Journal on Theoretical and Applied Research in Mechanical Engineering , 2012,
Abstract: In this paper, an overall review of the different parameter affecting on formability of tailor-welded blanks process is presented so that other researchers can concentrate on same to further critical investigations in this area. Tailor-welded blanks has been widely used in automobile and aerospace application now-a-days. It is the combination of more than or equal to two sheets having different material, thickness and coatings. Efforts have been put for determining the formability of TWB by various authors. Authors have been compared various test data for formability tests of TWB analytically with the help of various software. They have compared analytical data with practical data which were carried out in early 90’s for formability test when various software were not available. The testing of data and analyzing them by generating Forming Limit Diagram (FLD) for various tests parameters carried out by Limit Dome Height (LDH) test has been being much simpler analytically rather than conducting them practically. The efforts have also been put to conduct data and to verifying them analytically for deep drawing process of formability for TWB sheets with the help of various available software codes. Future scope may include to conduct data practically and to analyzed them by varying various test parameters for deep drawing process of a cylindrical cups on a new software HYPERWORKS which is now-a-days immerging as a powerful tool for software applications due to its some key features of being more efficient and accurate than other available software codes. The analyzing process is very fast, reliable and accurate compare to other finite element code available in the market.
Review on Tube Hydroforming Process with Considerable Parametric Effect
Vijay. R. Parekh,Jay. Shah,B. C. Patel
International Journal on Theoretical and Applied Research in Mechanical Engineering , 2012,
Abstract: In this paper, an overall review of the different parameter affecting on tube hydroforming process is presented so that other researchers can concentrate on same to further critical investigations in this area. Tube hydro forming is one of the most acceptable unconventional metal forming processes which is widely used to form various tubular components. In this process, tubes are formed into different shapes using internal pressure and axial compressive loads simultaneously to force a tubular blank to conform the shape of a given die cavity. The main process parameters in hydroforming are the inner pressure and the material feeding, where a correct combination of these parameters is crucial for the success of the process. Finite Element simulations are powerful tools for estimating the process parameters in an automated procedure. Hyper works is software which is having applicability to simulate the appropriate section of the tube profile for in depth parametric analysis.
SYNTHESIS AND ANTICONVULSANT ACTIVITY OF SOME NOVEL SEMICARBAZONE DERIVATIVES CONTAINING QUINOXALINE MOIETY
Rakesh Sahu*, Sonal Tiwari, Jay Kumar Chandra and Prabhat Kumar Patel
International Journal of Pharmaceutical Sciences and Research , 2012,
Abstract: Various 1-(substituted benzylidene)-5-(3-hydroxyquinoxaline-2-yl) carbonohydrazide were synthesized starting from orthophenylenediamine. Structures of all the compounds were confirmed on the basis of spectral analyses. All the newly synthesized compounds were screened for anticonvulsant activity. Some of the compounds showed significant anticonvulsant activity with no neurotoxicity
Page 1 /5593
Display every page Item


Home
Copyright © 2008-2017 Open Access Library. All rights reserved.