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Search Results: 1 - 10 of 801263 matches for " Javier de Jesús Mora García "
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Frecuencia de anticuerpos contra Neospora caninum en ganado bovino del noreste de México
José Antonio Salinas Meléndez,Javier de Jesús Mora García,Juan José Zárate Ramos,Víctor Manuel Riojas Valdés
Veterinaria México , 2005,
Abstract: El objetivo en esta investigación epidemiológica fue determinar la frecuencia de anticuerpos contra Neospora caninum en ganado lechero y productor de carne en la zona noreste de México. El presente estudio se llevó a cabo con 44 hatos bovinos pertenecientes a diferentes localidades de Coahuila, Nuevo León y Tamaulipas. En el estudio se analizaron 591 muestras de ganado bovino. Para la detección de anticuerpos contra Neospora caninum se utilizó un producto comercial. En Coahuila se observó una frecuencia de 45%; en Nuevo León, 40%; y en Tamaulipas, 16%. La frecuencia en la región noreste de México fue de 36%. Los resultados obtenidos del presente estudio permitieron establecer la existencia de animales seropositivos al protozoario Neospora caninum, en el noreste de México. La evidencia serológica fue advertida tanto en producción de leche como de carne. Tales datos indican que deben aumentarse los esfuerzos en el área zoosanitaria relacionada con las campa as de control y erradicación de las enfermedades para tener adecuadas condiciones y alcanzar mejores niveles de producción en la zona de estudio.
Películas de óxidos sobre acero inoxidable 316 (POSAI316) como electrodo indicador de pH en medio no acuoso
Francisco Javier García Gómez,José de Jesús Pérez Saavedra,Socorro Marquez Vargas
Revista de la Sociedad Química de México , 1997,
Abstract:
Tratamiento endoscópico del reflujo de vesicoureteral en pediatría: Experiencia preliminar con la inyección subureteral de coaptite?
Mora Durbán,Miguel Julián; Navarro Sebastián,Francisco Javier; Mu?oz Delgado,María Belén; García González,Jesús Isidoro; Paniagua Andrés,Pedro Dionisio;
Archivos Espa?oles de Urología (Ed. impresa) , 2006, DOI: 10.4321/S0004-06142006000500006
Abstract: objectives: to review our experience in the endoscopic treatment of vesicoureteral reflux (vur) in children with the subureteral injection of calcium hydroxyapatite (coaptite?). methods: the serie includes thirteen children whose age ranged between 6 and 13 years. the coaptite? implant was injected subureterally to 20 ureteral units (uu) affected by vur grades i-iv. vur was unilateral in six patients (46%), bilateral in seven (54%). there were 7 primary cases and 6 secondary to bladder dysfunction and duplex systems. results: mean follow-up was 19 months (6-28 months). vur was cured in 75% of cases after a single injection. a second injection resolved 2 out of 4 treated uu (50%) rendering a global success rate of 85%. this cure rate was achieved for 13 and 7 procedures treating primary and secondary vur, respectively. 77% of patients reported no adverse events with only 23% of them complaining of transient mild lumbar and hypogastric discomfort limited to the .rst postoperative day. in 2 children postoperative urinary infection was detected. conclusions: endoscopic subureteral injection with coaptite? is a simple technique well tolerated in children. in 85% of primary and secondary cases cure was achieved with minimal morbidity.
Population structure and reproductive behavior of Sinaloa cichlid Cichlasoma beani (Jordan, 1889) in a tropical reservoir
Melgen A. García-Lizárraga,Francisco Enrique Soto-Franco,Javier Marcial de Jesús Ruiz Velazco-Arce,José Iván Velázquez-Abunader
Neotropical Ichthyology , 2011,
Abstract: The population structure and reproductive condition of the Sinaloa cichlid Cichlasoma beani from samples obtained from June 2000 to July 2001 were determined. Samples in the first week each month from the largest trader of tilapia in the Aguamilpa Reservoir in Mexico and were caught in gillnets (9.6 and 11.4 cm stretch-mesh size). Of 596 specimens, there were 427 males and 169 females; monthly sex ratio, frequency of lengths by the multinomial distribution, timing of reproduction, condition index, and size at first maturity was determined. Differences in the sex ratio and monthly totals were significant, favoring males, except for September 2000 and March 2001. From one (August 2000) to three modal groups (July 2000 and June 2001) were identified by size. There were no significant differences in standard length weight relationships by sex, which indicated that a shared model for both genders is appropriate, and isometric growth was detected. Based on the proportion of mature and partially matures fish, the main reproductive period was April through June; size at first maturity was 18.9 cm. Water temperature was not significantly related to the percentage of mature and partially matures Sinaloa cichlids or spawning. These findings provide information for regulating the Cichlasoma beani fishery in this region such minimum legal size and non-fishing period. Se determinó la estructura poblacional y condición reproductiva del cíclido de Sinaloa Cichlasoma beani desde junio de 2000 a julio de 2001. Las muestras se obtuvieron de la captura comercial de tilapia en el embalse de Aguamilpa, México durante la primera semana de cada mes. Los especímenes se capturaron con redes de enmalle (9,6 y 11,4 cm de tama o de malla). De los 596 organismos recolectados, 427 fueron machos y 169 hembras. Se determinó la proporción de sexos mensual, grupos modales de tallas a través de una distribución multinomial, época reproductiva, índice de condición y talla de primera madurez. Se encontraron diferencias significativas en la proporción de sexos total y mensual favoreciendo a los machos, excepto en septiembre de 2000 y marzo de 2001. Se identificaron desde uno (agosto de 2000) hasta tres grupos modales de tallas (julio de 2000 y junio de 2001). No se encontraron diferencias significativas en la relación longitud patrón - peso total por sexo, lo que sugiere que el uso de un solo modelo para ambos sexos es adecuado, presentando crecimiento de tipo isométrico. Con base en la proporción de organismos parcialmente maduros y maduros, el pico principal de reproducción fue desde abril
Antiprotozoal Activity of a Thymus vulgaris Methanol Extract and Its Fractions  [PDF]
Jesús Norberto Garza-González, Javier Vargas-Villarreal, Ma Julia Verde-Star, Catalina Rivas-Morales, Azucena Oranday-Cárdenas, Magda E. Hernandez-García, Laura De La Garza-Salinas, Francisco González-Salazar
Health (Health) , 2017, DOI: 10.4236/health.2017.97079
Abstract:
Introduction: Thymus vulgaris is used in traditional medicine to treat gastrointestinal diseases because of its antifungal, antibacterial, and antispasmodic activity. Objective: To verify whether Thymus vulgaris also has antiprotozoal activity against Trichomonas vaginalis, Giardia lamblia and Entamoeba histolytica trophozoites. Materials and methods: Conventional cultures of parasites were measured on the third day during the logarithmic growth phase. The antiprotozoal activity of the methanol extract and its fractions were evaluated comparing growth in cultures with and without extracts. Next, the extract was fractionated by polarity-based partitioning. Then, the purity of each fraction was determined by thin layer chromatography (TLC). The percentage of growth inhibition was calculated with respect to untreated controls. The 50% inhibitory concentration (IC50) of each extract was calculated by PROBIT analysis. Results: We found that a methanol extract of the aerial parts of Thymus vulgaris, at 300 μg/mL, inhibited the in vitro growth of G. lamblia and T. vaginalis, while E. histolytica growth was poorly inhibited. The methanol extract was further separated into mixtures of ursolic, oleanolic, and betulinic acids. The IC50 values of ursolic acid against G. lamblia and T. vaginalis were 8.12 μg/mL and 5.51 μg/mL, respectively. Conclusions: The methanol extract fraction containing ursolic acid obtained from Thymus vulgaris has antiprotozoal activity against G. lamblia and T. vaginalis trophozoites.
Identificación de variedades de maíz sobresalientes considerando el modelo AMMI y los índices de Eskridge
González Huerta, Andrés;Sahagún Castellanos, Jaime;Vázquez García, Luis Miguel;Rodríguez Pérez, Juan Enrique;Pérez López, Delfina de Jesús;Domínguez López, Aurelio;Franco Mora, Omar;Balbuena Melgarejo, Artemio;
Agricultura técnica en México , 2009,
Abstract: this study was carried out in 2004 at metepec, el cerrillo piedras blancas (two sowing dates), and jocotitlán, towns located in the toluca-atlacomulco valley, in the state of mexico; the main objective was to identify high yielding maize (zea mays l.) genotypes by using the additive main effects and multiplicative interaction analysis model (ammi), four eskridge's criteria, and the genotype by stability index analysis. at each location, twenty-five varieties were sown in a randomized complete block design with four replications. the combined analysis of variance was computed for this series of experiments over locations. the analysis with the ammi model show that environment, genotype, genotype by environment interaction, and the first principal component in the pca analysis were highly significant (p<0.01). only 2% of total sum of squares of the ammi model was assigned to the model's residual. the ixtlahuaca variety (check) outperformed palomero toluque?o in 2.3 t ha-1, and outyielded the lowest and highest cacahuacintle yielders by 2.3 and 1.48 t ha-1, respectively. chalque?o, eta 13, cóndor, h-33, h-40, h-44, and h-90e outperformed the check variety from 1.0 to 2.25 t ha-1. the ammi model, the four eskridge's criteria, and the genotype by stability index analysis identified chalque?o, h-33, h-40, hit-3, san lucas, and vs-46e as stable varieties, and only the first three outyielded (p<0.01) the check variety and the overall mean; palomero toluque?o and cacahuacintles 4 and 5 were classified as unstable varieties and show a yield significantly lower (p<0.01) than the check and the overall mean.
Structural and Functional Perturbation of Giardia lamblia Triosephosphate Isomerase by Modification of a Non-Catalytic, Non-Conserved Region
Gloria Hernández-Alcántara, Alfredo Torres-Larios, Sergio Enríquez-Flores, Itzhel García-Torres, Adriana Castillo-Villanueva, Sara T. Méndez, Ignacio de la Mora-de la Mora, Saúl Gómez-Manzo, Angélica Torres-Arroyo, Gabriel López-Velázquez, Horacio Reyes-Vivas, Jesús Oria-Hernández
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0069031
Abstract: Background We have previously proposed triosephosphate isomerase of Giardia lamblia (GlTIM) as a target for rational drug design against giardiasis, one of the most common parasitic infections in humans. Since the enzyme exists in the parasite and the host, selective inhibition is a major challenge because essential regions that could be considered molecular targets are highly conserved. Previous biochemical evidence showed that chemical modification of the non-conserved non-catalytic cysteine 222 (C222) inactivates specifically GlTIM. The inactivation correlates with the physicochemical properties of the modifying agent: addition of a non-polar, small chemical group at C222 reduces the enzyme activity by one half, whereas negatively charged, large chemical groups cause full inactivation. Results In this work we used mutagenesis to extend our understanding of the functional and structural effects triggered by modification of C222. To this end, six GlTIM C222 mutants with side chains having diverse physicochemical characteristics were characterized. We found that the polarity, charge and volume of the side chain in the mutant amino acid differentially alter the activity, the affinity, the stability and the structure of the enzyme. The data show that mutagenesis of C222 mimics the effects of chemical modification. The crystallographic structure of C222D GlTIM shows the disruptive effects of introducing a negative charge at position 222: the mutation perturbs loop 7, a region of the enzyme whose interactions with the catalytic loop 6 are essential for TIM stability, ligand binding and catalysis. The amino acid sequence of TIM in phylogenetic diverse groups indicates that C222 and its surrounding residues are poorly conserved, supporting the proposal that this region is a good target for specific drug design. Conclusions The results demonstrate that it is possible to inhibit species-specifically a ubiquitous, structurally highly conserved enzyme by modification of a non-conserved, non-catalytic residue through long-range perturbation of essential regions.
Variación morfológica de semillas de Taxus globosa Schltdl. provenientes de dos regiones geográficas de México
Ramírez-Sánchez, Susana E.;López-Upton, Javier;García de los Santos, Gabino;Vargas-Hernández, J. Jesús;Hernández-Livera, Adrián;Ayala-Garay, óscar J.;
Revista fitotecnia mexicana , 2011,
Abstract: taxus globosa schltdl. is the only species of the genus taxus that grows in mexico and is protected by the mexican government. its bark and leaves contain taxol, a high value compound used as a cancer drug. natural regeneration of taxus globosa is by seeds which germinate scarcely and present dormancy. the present study was done in order to determine the morphological variation of taxus globosa seeds and to learn if seed dormancy is caused by physical factors. collected seeds from northern (nuevo león) and central (hidalgo and queretaro) méxico were used to measure seed dimensions (length, width, area, perimeter and embryo/megagametophyte ratio) by image analysis, in addition to volumetric weight, and weight of 1000 seeds. to evaluate the physical characteristics of the seed coat, a scarification test with sulfuric acid for 5, 10, 15, 20, 25 and 30 min was done followed a tetrazolium viability test. seed coat hardness and imbibition rate were also measured. there were differences in seed size betwee geographical origins (28 % bigger in the northern region). the embryo/megagametophyte ratio of was only 4% in seeds from the northern region and 3% in the central region. seeds of both regions only supported 5 min immersed in h2so4, and seeds from the northern region were harder (1.29 vs. 0.86 kg cm-2). seeds from the northern absorbed more water than those from the central region. taxus globosa seeds do not need scarification to soften the seed coat, and the possible cause of seed dormancy appears to be their undeveloped embryos.
Comportamiento maternal alrededor del parto y reconocimiento madre-cría en ovinos Pelibuey
Ramírez Martínez, Miriam Gloria;Soto González, Rosalba;Poindron Massot, Pascal;álvarez Ramírez, Lorenzo;Valencia Méndez, Javier de Jesús;González Díaz, Francisco Rodolfo;Terrazas García, Angélica María;
Veterinaria México , 2011,
Abstract: maternal and social behavior in multiparous pelibuey ewes was assessed under intensive production system. the social behavior was recorded several days before and during birth. mother-young behavior during the first hour after birth was recorded. a selective maternal test was performed at 2 hours postpartum. eight hours after birth, a double choice test was done in mothers to asses their ability to discriminate between the own or alien lamb. while a similar double choice test was performed in 12 hours-old lambs. the agitation index when the ewes were tested without companions was lower in parturient ewes than in145 days pregnant ewes and non pregnant ewes [parturient ewes: (-0.59 ± 0.9), 145 days pregnant ewes: (2.6 ± 0.7) and non pregnant ewes (4.2 ± 0.9) p < 0.05]. during the first hour after birth the latency to stand up, to begin to look for the udder and to suck was shorter in male than female lambs, also the male lambs sucked for longer time than females (p < 0.05). during this time mothers emitted more high-pitched bleats than low-pitched bleats (p < 0.05). besides, the ewes got shorter latencies to lick the area of head and thorax of the lamb than its tail, but they licked more frequently the lamb's tail and thorax (p < 0.03). two hours postpartum all mothers were selective, they showed clear preference to accept to the udder their own lamb and reject actively the alien ones (p < 0.05). at eight or 12 hours, mothers and lambs spent longer time watching and staying with their own familiar animal than with the alien ones (p < 0.05). it is concluded that pelibuey ewes show an adequate maternal temperament, and the behavior of the newborn lamb could be affected because of its sex.
Incidence, organ dysfunction and mortality in severe sepsis: a Spanish multicentre study
Jesús Blanco, Arturo Muriel-Bombín, Víctor Sagredo, Francisco Taboada, Francisco Gandía, Luís Tamayo, Javier Collado, ángel García-Labattut, Demetrio Carriedo, Manuel Valledor, Martín De Frutos, María-Jesús López, Ana Caballero, José Guerra, Braulio álvarez, Agustín Mayo, Jesús Villar, the Grupo de Estudios y Análisis en Cuidados Intensivos (G.R.E.C.I.A.)
Critical Care , 2008, DOI: 10.1186/cc7157
Abstract: We conducted a prospective, observational, multicentre cohort study, carried out over two 3-month periods in 2002. Our aims were to determine the incidence of severe sepsis among adults in ICUs in a specific area in Spain, to determine the early (48 h) ICU and hospital mortality rates, as well as factors associated with the risk of death.A total of 4,317 patients were admitted and 2,619 patients were eligible for the study; 311 (11.9%) of these presented at least 1 episode of severe sepsis, and 324 (12.4%) episodes of severe sepsis were recorded. The estimated accumulated incidence for the population was 25 cases of severe sepsis attended in ICUs per 100,000 inhabitants per year. The mean logistic organ dysfunction system (LODS) upon admission was 6.3; the mean sepsis-related organ failure assessment (SOFA) score on the first day was 9.6. Two or more organ failures were present at diagnosis in 78.1% of the patients. A microbiological diagnosis of the infection was reached in 209 episodes of sepsis (64.5%) and the most common clinical diagnosis was pneumonia (42.8%). A total of 169 patients (54.3%) died in hospital, 150 (48.2%) of these in the ICU. The mortality in the first 48 h was 14.8%. Factors associated with early death were haematological failure and liver failure at diagnosis, acquisition of the infection prior to ICU admission, and total LODS score on admission. Factors associated with death in the hospital were age, chronic alcohol abuse, increased McCabe score, higher LODS on admission, ΔSOFA 3-1 (defined as the difference in the total SOFA scores on day 3 and on day 1), and the difference of the area under the curve of the SOFA score throughout the first 15 days.We found a high incidence of severe sepsis attended in the ICU and high ICU and hospital mortality rates. The high prevalence of multiple organ failure at diagnosis and the high mortality in the first 48 h suggests delays in diagnosis, in initial resuscitation, and/or in initiating appropriate ant
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