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Search Results: 1 - 10 of 481519 matches for " Javier Jesús De La; "
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Post-transplant plasma cell hepatitis in a liver transplant patient treated with pegylated interferon plus ribavirin  [PDF]
Miguel Jiménez-Pérez, Francisco Javier Rando-Mu?oz, Rocío González-Grande, Fernando González-Panizo Tamargo, Jesús de la Cruz Lombardo, Juan Miguel Rodrigo López, Román Manteca González
Open Journal of Gastroenterology (OJGas) , 2013, DOI: 10.4236/ojgas.2013.37053

The recurrence of hepatitis C after a liver transplant remains an important cause of graft loss and retransplant. Antiviral therapy with peginterferon plus ribavirin (PEG-INF/RBV) can achieve a sustained viral response and histological improvement in a high percentage of cases. However, this treatment is not exempt from important side effects or from the possibility of precipitating rejection, with the resulting graft loss. We report the case of a liver transplant patient who received treatment with PEG-INF/RBV and developed plasma cell hepatitis as the presenting form of rejection.


Determining the specific status of the Iberian sturgeons by means genetic analyses of old specimens  [PDF]
Francisca Robles, Belén Cano-Roldán, Carmelo Ruiz Rejón, Luís Javier Martínez-González, María Jesús álvarez-Cubero, José Antonio Lorente, José Antonio Riquelme Cantal, Pedro Aguayo de Hoyos, Javier Carrasco Rus, Miguel Cortés Sánchez, María Dolores Simón Vallejo, Manuel Ruiz Rejón, Roberto de la Herrán
Advances in Bioscience and Biotechnology (ABB) , 2010, DOI: 10.4236/abb.2010.13024
Abstract: To clarify the species status of sturgeon from rivers of the Iberian Peninsula, eight molecular markers (4 nuclear and 4 mitochondrial) have been analysed in different specimens from historical museum samples and prehistoric samples from archaeological sites. These analyses indicate that one of these specimens (UGP captured in the Guadalquivir River in the 19th century) is A. sturio, based on all the eight molecular markers, four of them used from the first time in this study. In previous analyses based on 5 genetic markers, our group assigned two specimens captured in this river in the 1970-80s (EBD8173 and EBD8401) to the species A. naccarii, suggesting the presence of this species in the Iberian Peninsula. In this work, this conclusion is drawn after successfully obtaining a mitochondrial marker in a very old scute from a prehistoric site (Acinipo, about 1500 BC, from the Guadalquivir River basin). On the other hand, in the specimen EBD8174 captured in the Guadalquivir in 1975, we have obtained two new mitochondrial markers confirming that it can be considered A. sturio for all the mitochondrial markers, but nuclear ones identify it as A. naccarii. Finally, two very old samples (Nerja E-VI and Nerja N/62-63) were not successfully characterized by any molecular markers. Some aspects and consequences of our results are discussed, such as the origin of the “mosaic” specimen EBD8174 and, above all, the native status of A. naccarii in historic and prehistoric times in the southern Iberian Peninsula.
Caracterización de Pseudotsuga menziesii (MIRB.) Franco en el centro de México: Implicaciones para su conservación
Ventura Ríos, Araceli;López Upton, Javier;Vargas Hernández, J. Jesús;Guerra de la Cruz, Vidal;
Revista fitotecnia mexicana , 2010,
Abstract: the objective of this study was to describe the ecological conditions of 29 stands of pseudotsuga menziesii (mirb.) franco located in the states of hidalgo, puebla and tlaxcala, in central méxico. an estimated of 9029 adult douglas-fir trees are growing in an area of 682 ha, located in altitudes between 2450 and 3400 m on soils with slightly acidic ph, rich in organic matter and sandy loam and loam texture in most cases. the locations have a temperate climate, with an average temperatures ranging from 10.1 to 14.0 °c and annual rainfall range from 611 to 1109 mm. p. menziesii coexists with abies eligiosa (kunth) schltdl. et cham. and with several species of the genus pinus and quercus, facing n, nw and ne. tree population size varies from 4 to 1450 matures trees; 11 stands have less than 100 adult trees. the natural regeneration is low in all of them, and the stands are fragmented within their natural range. based on a cluster analysis, two clusters of stands were found: one located at hidalgo state (zone i), and another grouping in the tlaxcala and puebla (zone ii) stands. each zone has six groups of populations. genetic material exchange is recommended inside groups and occasionally among groups of populations to restore gene flow and encourage genetic variability. key aspects are discussed for the conservation of these small stands.
Nefrectomía radical laparoscopica: Técnica, resultados y complicaciones
Aguilera Bazán,Alfredo; Pérez Utrilla,Manuel; Girón,Manuel; Cisneros Ledo,Jesús; de la Pe?a Barthel,Javier;
Actas Urológicas Espa?olas , 2009, DOI: 10.4321/S0210-48062009000500012
Abstract: surgery is the treatment of choice for clear cell renal carcinoma not responding to chemotherapy, radiotherapy, or immunotherapy. the surgical procedure used has evolved over time in the past 40 years, mainly because of the development and widespread use of diagnostic procedures such as ultrasonography and ct. as a direct consequence, parenchymal-sparing surgery was no longer only used for patients with solitary kidneys and its indication started to be extended to patients with tumors up to 4 cm in diameter, in whom it has been shown to be a safe and effective alternative to radical nephrectomy. the other important milestone in development of renal cancer surgery undoubtedly was the revolution started in the 90s with advent of laparoscopic renal surgery, which has become established over the past 20 years approximately. laparoscopic surgery initially raised concern about oncological safety, but clinical series with sufficiently long follow-up times and large sample sizes are now available to consider the laparoscopic approach as a reliable procedure. technological development has caused the laparoscopic technique to be no longer seen as a procedure for the future, but rather as an absolutely current technique which should be implemented in most urology departments. implementation of any new procedure usually involves a number of complications which we should be prepared to assume, while making every effort to try and prevent them. it is therefore essential to develop, and to implement using common sense, a training program on the procedure. selection of patients and conditions to be treated is a crucial part of such a program.
Nefroureterectomía laparoscópica: nueva posición para el manejo ureteral
Aguilera Bazán,Alfredo; Alonso y Gregorio,Sergio; Pérez Utrilla,Manuel; Cansino Alcaide,Ramón; Cisneros Ledo,Jesús; Pe?a,Javier de la;
Archivos Espa?oles de Urología (Ed. impresa) , 2007, DOI: 10.4321/S0004-06142007000600009
Abstract: objectives: the main challenge of laparoscopic nephroureterectomy is the management of distal ureter, which also will have an important repercussion in the oncological outcome of many cases. we present our experience in such aspect, considering that we performed the last five laparoscopic nephroureterectomies in forced trendelemburg position, resulting in a more comfortable and safe management of the distal ureter. methods: between august and december 2006 we performed five purely laparoscopic nephroureterectomies with bladder cuff positioning the patient in forced trendelemburg, a position similar to that of laparoscopic radical cystectomy or prostatectomy. results: mean surgical time was 182 minutes (170-210). mean blood loss was 100 cc and no patient required transfusion. mean hospital stay was four days. conclusions: we believe this position is a good alternative for the management of the distal ureter during the laparoscopic approach. the technique is very similar to open surgery, which continues being the gold standard today.
Neurofibroma de la vejiga: caso clínico y revisión de la literatura
Cabrera Castillo,Pedro Manuel; Alonso y Gregorio,Sergio; Cansino Alcaide,José Ramón; Aguilera Basan,Alfredo; Pe?a Barthel,Javier Jesús De La;
Archivos Espa?oles de Urología (Ed. impresa) , 2006, DOI: 10.4321/S0004-06142006000900008
Abstract: objetive: the prevalence of the disease is 1/3000 newborns; it is more frequent in men than in women with a 3:1 ratio in all races. genitourinary tract neurofibromas usually arise from the pelvic and bladder nerves, and the prostatic plexus. bladder is the most frequently affected organ of the urinary tract; bladder neurofibromatosis may present as a diffuse infiltrative process or an isolated neurofibroma. bladder neurofibromas arise from nervous ganglia of the bladder wall and stain positive for protein s-100 and type iv collagen with immunohistochemical techniques. methods: we performed a bibliographic review about urinary tract neurofibromas, and specifically of bladder neurofibroma. we report the case of a 45-year-old female consulting for voiding symptoms and recurrent urinary tract infections. imaging tests showed a mass in the left lateral wall of the bladder and diffuse thickening of the bladder wall. the thickening of the bladder wall is the most characteristic finding in imaging tests, which may also be present in other diseases such as inflammatory pseudotumor and leiomyoma, so that final diagnosis should be achieved by pathologic study. results: the case is relevant for the absence of previous diagnosis of neurofibromatosis, being bladder involvement its clinical debut. this is why it was difficult to suspect the final diagnosis: the absence of other characteristic clinical manifestations of the disease. transurethral resection of the tumor was performed and pathologic and immunohistochemical studies offered the final diagnosis. the patient was followed in the urology clinic and also sent to the internal medicine department to rule out other organs involvement of the disease. conclusions: neurofibromatosis is a rare systemic disease, and urinary tract involvement is rarer. bladder is the most frequently involved organ in the urinary tract, generally as a diffuse infiltration or more rarely a solitary tumor. the final diagnosis is pathological and immuno
Feocromocitoma: Tratamiento laparoscópico
Cabrera Castillo,Pedro Manuel; Aguilera Bazán,Alfredo; Cansino Alcaide,José Ramón; álvarez Maestro,Mario; Pe?a Barthel,Javier Jesús De la;
Archivos Espa?oles de Urología (Ed. impresa) , 2007, DOI: 10.4321/S0004-06142007000900015
Abstract: objective: we report this clinical case not only for the laparoscopic approach of a pheochromocytoma but also because of its particular aggressiveness and oddity of its clinical presentation. methods: 44 years old male presenting with oppressive chest pain with accompanying vegetative symptoms, who was diagnosed of right adrenal pheochromocytoma. results: after the diagnosis of pheochromocytoma was established and double adrenergic blockage implemented, transperitoneal laparoscopic surgery was performed. pathological analysis of the surgical specimen confirmed the clinical diagnosis of pheochromocytoma. patient was discharged home two days after surgery without any complication. conclusions: the laparoscopic approach of adrenal pheochromocytoma is possible and safe in centres with laparoscopic experience, obtaining the same results than open surgery, offering advantages for the patient such as less pain, smaller incisions, and early ambulation, which results in a shorter hospital stay.
Antiprotozoal Activity of a Thymus vulgaris Methanol Extract and Its Fractions  [PDF]
Jesús Norberto Garza-González, Javier Vargas-Villarreal, Ma Julia Verde-Star, Catalina Rivas-Morales, Azucena Oranday-Cárdenas, Magda E. Hernandez-García, Laura De La Garza-Salinas, Francisco González-Salazar
Health (Health) , 2017, DOI: 10.4236/health.2017.97079
Introduction: Thymus vulgaris is used in traditional medicine to treat gastrointestinal diseases because of its antifungal, antibacterial, and antispasmodic activity. Objective: To verify whether Thymus vulgaris also has antiprotozoal activity against Trichomonas vaginalis, Giardia lamblia and Entamoeba histolytica trophozoites. Materials and methods: Conventional cultures of parasites were measured on the third day during the logarithmic growth phase. The antiprotozoal activity of the methanol extract and its fractions were evaluated comparing growth in cultures with and without extracts. Next, the extract was fractionated by polarity-based partitioning. Then, the purity of each fraction was determined by thin layer chromatography (TLC). The percentage of growth inhibition was calculated with respect to untreated controls. The 50% inhibitory concentration (IC50) of each extract was calculated by PROBIT analysis. Results: We found that a methanol extract of the aerial parts of Thymus vulgaris, at 300 μg/mL, inhibited the in vitro growth of G. lamblia and T. vaginalis, while E. histolytica growth was poorly inhibited. The methanol extract was further separated into mixtures of ursolic, oleanolic, and betulinic acids. The IC50 values of ursolic acid against G. lamblia and T. vaginalis were 8.12 μg/mL and 5.51 μg/mL, respectively. Conclusions: The methanol extract fraction containing ursolic acid obtained from Thymus vulgaris has antiprotozoal activity against G. lamblia and T. vaginalis trophozoites.
El rol de Cuidador de personas dependientes y sus repercusiones sobre su Calidad de Vida y su Salud
López Gil,Ma Jesús; Orueta Sánchez,Ramón; Gómez-Caro,Samuel; Sánchez Oropesa,Arancha; Carmona de la Morena,Javier; Alonso Moreno,Francisco Javier;
Revista Clínica de Medicina de Familia , 2009, DOI: 10.4321/S1699-695X2009000200004
Abstract: objective. to determine caregiver burden and its repercussions on quality of life, physical and mental health and social life and the use for healthcare resources (frequency). design. observational, analytical, case control study. setting. primary health care centre in an urban setting. participants. the case group was made up of 156 primary caregivers and the control group of 156 personas assigned to the primary health care centre who were not primary care givers. they were paired by age, gender and number of chronic diseases. measurements. clinical and socio-demographic characteristics, caregiver role characteristics (kinship, time performing role of caregiver, etc.), caregiver burden (zarit scale), frequency, perceived health, subjective quality of life (nottingham health profile), presence of anxiety and depression symptoms (gads-18), family functioning (family apgar) and perception of family and social support (duke-unc questionnaire). results. according to the zarit scale, burden was present in 66.4% of caregivers. compared to 31.4% of persons in the control group, 48.1% of caregivers considered their health was poor or very poor (or = 2.02; 95% ci: 1.27 - 3.21). the mean frequency in the last year was 8.37 visits/year in the caregiver group and 7.12 visits/year in the control group (p< 0.01). a higher prevalence of anxiety and depression was observed in the caregiver group, and a greater frequency of possible family dysfunction and sensation of insufficient social support. conclusions. the results indicate the need for multidisciplinary supportive and preventive interventions for caregivers. such interventions have obtained positive results in several aspects both for the caregiver and the person cared for person. these interventions need to be adapted to the specific characteristics and needs of each caregiver.
Nefrectomía radical laparoscópica en piezas quirúrgicas de gran tama?o
Alonso y Gregorio,Sergio; Sánchez,S.; Soler,C.; Rando,A.; Girón,M.; Tabernero Gómez,ángel J.; Aguilera,A.; Cisneros Ledo,Jesús; Pe?a Barthel,Javier de la;
Actas Urológicas Espa?olas , 2009, DOI: 10.4321/S0210-48062009000700007
Abstract: introduction: the retroperitoneal surgery is the clearer indication for the laparoscopic approach. still there are indications for open surgery because of the complexity of the patient and the surgeon experience. objectives: the main objective is to report our experience of laparoscopic radical nephrectomies in patient with tumors greater than 7 cm. or surgical specimens with more than 700 gr. of weight. we analyze their characteristics, complications rate, surgical time, postoperative outcome and hospital stay. materials and methods: since july 2004 to july 2008 we have performed 104 laparoscopic radical nephrectomies. we have selected 41 patients with characteristics of big surgical specimens. results: the average surgical time has been of 184,3 min. only 1 case has been converted into open surgery and only 1 intraoperative death because of cardiologic arrhythmia. the average hospital stay has been of 3,51 days. the complications rate and postoperative outcome are similar to the whole series. discussion: laparoscopic nephrectomy is technically less complex than radical prostatectomy. however, their possible complication implies a much bigger severity. the more complex cases must be approach laparoscopically only after a wide experience. actually, in our department we usually indicate an open approach when surgical specimen crossover the abdominal middle line and in those cases where the tumoral thrombus affect the main renal vein and/or the vena cava.
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