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Search Results: 1 - 10 of 208952 matches for " Jamie L. Jennell "
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Halofuginone- and Chitosan-Coated Amnion Membranes Demonstrate Improved Abdominal Adhesion Prevention
Scott Washburn,Jamie L. Jennell,Steve J. Hodges
The Scientific World Journal , 2010, DOI: 10.1100/tsw.2010.234
Abstract:
Motivational Priming Predicts How Noxious Unconditioned Stimuli Influence Affective Reactions to Emotional Pictures  [PDF]
Amy E. Williams, Jamie L. Rhudy
Psychology (PSYCH) , 2012, DOI: 10.4236/psych.2012.310133
Abstract: Motivational priming theory (MPT) and preparedness theory generate competing hypotheses about the impact of an aversive US on responses to an affective foreground. MPT predicts the aversive US will facilitate negative emotional reactions to unpleasant pictures and inhibit positive emotional reactions to pleasant pictures. Preparedness theory predicts an aversive US will increase negative emotional reactions to unpleasant pictures, but will not impact responses to pleasant pictures. The present study (N = 125) compared these competing hypotheses by assessing how noxious shocks and non-noxious noises influence responses to emotional pictures. Following each picture, participants rated how the picture made them feel using the Self Assessment Manikin. Results supported MPT - noxious USs, but not non-noxious USs, facilitated negative emotional reactions to unpleasant pictures and inhibited positive emotional reactions to pleasant pictures.
AFM Investigation of the Organization of Actin Bundles Formed by Actin-Binding Proteins  [PDF]
Jamie L. Gilmore, Masahiro Kumeta, Kunio Takeyasu
Journal of Surface Engineered Materials and Advanced Technology (JSEMAT) , 2013, DOI: 10.4236/jsemat.2013.34A1002
Abstract:

AFM is a powerful technique for revealing the morphological features of various biological systems at high resolution. However, one of the complications of AFM is that samples must be attached to a flat surface in order to obtain images. This often requires the development of specialized methods depending on the sample which is being used. In this study, we developed a novel technique to image actin bundles on the mica surface. Using this technique, we were able to image molecular assemblies of F-actin with two actin remodeling proteins: α-actinin and Caprice. High resolution AFM images of F-actin fibers and bundle organization depicted two different types of molecular assemblies: F-actin bundles forming an elongated “zipper” structure in the presence of α-actinin, and bundles forming a perpendicularly crossing the mesh structure in the presence of Caprice.

Repetition of Less Common Sound Patterns: A Unique Relationship to Young Children’s Phonological Awareness and Word Reading
Jamie L Metsala
International Journal of English Linguistics , 2011, DOI: 10.5539/ijel.v1n2p3
Abstract: The current study examined predictors of concurrent phonological awareness in 95 Grade 1 children and of reading achievement 5 months later. Of primary interest was whether the repetition of nonwords with less versus more common sound patterns was a better predictor of these variables. Only the repetition of nonwords low in wordlikeness predicted unique variance in concurrent phonological awareness after measures of phonological memory and vocabulary. Similarly, nonword repetition for words low in wordlikeness accounted for unique variance in later reading after measures of fall reading, phonological memory, vocabulary, and phonological awareness. A fall phonological representations factor was directly related to later reading achievement. Results are discussed within a framework for which the representation of less common sound sequences has a robust relationship to reading acquisition, and for which awareness of the phonemic structure of language may be reducible to the representation of phonological information in lexical memory.
Review: Approaches to Teaching Wiesel’s “Night”, by Alan Rosen
Jamie L. Wraight
Journal of Historical Biography , 2008,
Abstract:
Matrix Stiffness Affects Endocytic Uptake of MK2-Inhibitor Peptides
Jamie L. Brugnano, Alyssa Panitch
PLOS ONE , 2014, DOI: 10.1371/journal.pone.0084821
Abstract: In this study, the role of substrate stiffness on the endocytic uptake of a cell-penetrating peptide was investigated. The cell-penetrating peptide, an inhibitor of mitogen-activated protein kinase activated protein kinase II (MK2), enters a primary mesothelial cell line predominantly through caveolae. Using tissue culture polystyrene and polyacrylamide gels of varying stiffness for cell culture, and flow cytometry quantification and enzyme-linked immunoassays (ELISA) for uptake assays, we showed that the amount of uptake of the peptide is increased on soft substrates. Further, peptide uptake per cell increased at lower cell density. The improved uptake seen on soft substrates in vitro better correlates with in vivo functional studies where 10–100 μM concentrations of the MK2 inhibitor cell penetrating peptide demonstrated functional activity in several disease models. Additional characterization showed actin polymerization did not affect uptake, while microtubule polymerization had a profound effect on uptake. This work demonstrates that cell culture substrate stiffness can play a role in endocytic uptake, and may be an important consideration to improve correlations between in vitro and in vivo drug efficacy.
Differential Effects of Krill Oil and Fish Oil on the Hepatic Transcriptome in Mice
Lena Burri,Jamie L. Barger
Frontiers in Genetics , 2011, DOI: 10.3389/fgene.2011.00045
Abstract: Dietary supplementation with ω-3 polyunsaturated fatty acids (ω-3 PUFAs), specifically the fatty acids docosahexaenoic acid (DHA; 22:6 ω-3) and eicosapentaenoic acid (EPA; 20:5 ω-3), is known to have beneficial health effects including improvements in glucose and lipid homeostasis and modulation of inflammation. To evaluate the efficacy of two different sources of ω-3 PUFAs, we performed gene expression profiling in the liver of mice fed diets supplemented with either fish oil (FO) or krill oil (KO). We found that ω-3 PUFA supplements derived from a phospholipid krill fraction (KO) downregulated the activity of pathways involved in hepatic glucose production as well as lipid and cholesterol synthesis. The data also suggested that KO-supplementation increases the activity of the mitochondrial respiratory chain. Surprisingly, an equimolar dose of EPA and DHA derived from FO modulated fewer pathways than a KO-supplemented diet and did not modulate key metabolic pathways regulated by KO, including glucose metabolism, lipid metabolism and the mitochondrial respiratory chain. Moreover, FO upregulated the cholesterol synthesis pathway, which was the opposite effect of krill-supplementation. Neither diet elicited changes in plasma levels of lipids, glucose, or insulin, probably because the mice used in this study were young and were fed a low-fat diet. Further studies of KO-supplementation using animal models of metabolic disorders and/or diets with a higher level of fat may be required to observe these effects.
Publication trends of natural history and field studies in herpetology
Malcolm L. McCallum,Jamie L. McCallum
Herpetological Conservation and Biology , 2006,
Abstract: .—Although natural history studies provide important information on the life histories of amphibians and reptiles,their publication has gradually declined over recent decades. We compared publication of natural history and total articles inHerpetologica and Journal of Herpetology over the lives of these two journals. We analyzed data using trends analysis and theindividual trends with regression techniques to describe changes in publication frequency. In Herpetologica, the number ofnatural history articles increased from 1936 through the 1960s, but these manuscripts were often short notes and isolatedobservations. The number of total publications and of natural history publications remained stable through the late 1960s.Although the total number of articles published in Herpetologica has declined in more recent times, the relative number of lifehistory publications has dropped much faster than the total production. Both the numbers of natural history articles and allarticles increased since the founding of Journal of Herpetology, but natural history articles have dropped substantially sincethe mid-1990s. When combining publishing trends for both journals, there was an obvious decrease in the proportion ofnatural history articles. Explanations for these reductions are complex but may include less grant funding, editorial decisions,additional competition from other journals, and the rise of molecular biology and genetic studies. Many of the ‘naturalhistory’ papers may have migrated to regional journals, foreign outlets, or one of many new specialized journals.
Confirmation of Pearl Millet-Napiergrass Hybrids Using EST-Derived Simple Sequence Repeat (SSR) Markers  [PDF]
Charlie D. Dowling, Byron L. Burson, Jamie L. Foster, Lee Tarpley, Russell W. Jessup
American Journal of Plant Sciences (AJPS) , 2013, DOI: 10.4236/ajps.2013.45124
Abstract:

Prospects for deploying perennial grasses that are currently considered leading candidates for dedicated energy crops over large acreages are debatable because of several limitations, including vegetative propagation or small seed size, low biomass production during the first growing season, and incomplete assessments of crop invasiveness risk. Pearl Millet-Napiergrass hybrids (PMN; Pennisetum glaucum [L.] R. Br. × P. purpureum Schumach.), in contrast, are large-seeded, sterile feedstocks capable of high biomass production during establishment year. Novel methods are warranted for confirmation of PMN hybrids, as traditional morphological observations can be inconclusive and chromosome number determination using cytological methods is laborious and time consuming. Six putative PMN lines were produced in this study, and 10 progeny from each line were evaluated using morphological traits, seed fertility, flow cytometry, and expressed sequence tag-simple sequence repeat (EST-SSR) markers. All putative hybrid lines were sterile and failed to produce seed. The PMN hybrids could not be distinguished from either parent using flow cytometry due to highly similar nuclear genome DNA contents. A number of paternal napiergrass-specific EST-SSRs were identified for each PMN line, and four paternal-specific EST-SSRs conserved across all napiergrass accessions were selected to screen the putative PMN hybrids. These EST-SSRs confirmed that all F1 individuals analyzed were PMN hybrids. The use of paternal-specific markers therefore provides a valuable tool in the development of both

Succinic Acid Production across Candidate Lignocellulosic Biorefinery Feedstocks  [PDF]
Yifeng Xu, Jamie L. Foster, James P. Muir, Byron L. Burson, Russell W. Jessup
American Journal of Plant Sciences (AJPS) , 2018, DOI: 10.4236/ajps.2018.911155
Abstract: Non-food lignocellulosic crops with both high biomass yields and superior adaptation to marginal lands have significant potential as biofuel feedstocks that can replace fossil fuels. Deployment of dedicated crops into single biofuels, however, has been reduced by conversion technology costs and low petroleum prices. Integrated biorefinery strategies, in which value-added coproducts are generated in conjunction with biofuels, by comparison offer opportunities to overcome this economic disadvantage. The objective of this research was to evaluate succinic acid accumulation across candidate lignocellulosic feedstocks. Feedstock entries included pearl millet x napiergrass hybrids (“PMN”; Pennisetum glaucum [L.] R. Br. × P. purpureum Schumach.), napiergrass (P. purpureum Schumach.), annual sorghum (Sorghum bicolor [L.] Moench), pearl millet (P. glaucum [L.] R. Br.), perennial sorghum (Sorghum spp.), switchgrass (Panicum virgatum L.), sunn hemp (Crotalaria juncea L.), giant miscanthus (Miscanthus × giganteus J. M. Greef & Deuter) and energy cane (Saccharum spp. L.). Replicated field plots, as well as an independent greenhouse trial, were characterized for succinic acid content. The PMN, napiergrass, sunn hemp and energy cane entries had greater (P ≤ 0.05) succinic acid yields, up to 556 kg·ha-1, in field trials. Napiergrass and PMN entries similarly had higher succinic acid yields under greenhouse conditions; however, irrigation treatments did not alter succinic acid accumulation in this study. Napiergrass, PMN, and energy cane thus are promising biorefinery feedstocks.
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