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Phenanthrenes of Eulophia ochreata Lindl.
Kshirsagar Rajendra,Kanekar Yogesh,Jagtap Suresh,Upadhyay Shakti
International Journal of Green Pharmacy , 2010,
Abstract: Pawra tribe of Satpuda mountain ranges that belong to Maharashtra region, India, is known to use tubers of Eulophia ochreata for rejuvenating and aphrodisiac properties and also for curing rheumatism. For systematic scientific validation of folk claims of E. ochreata tubers, we report here the collection, extraction, isolation and spectral characterization of molecules and also its evaluation for free radical scavenging activity. Isolation of molecules was carried out on activity-guided fractionation in 2,2 ′ -diphenyl-1-picrylhydrazyl assay. This is the first report of isolation of 9,10-Dihydro-2,5-Dimethoxyphenanthrene-1,7-diol and 5,7-Dimethoxyphenanthrene-2,6-diol from this orchid.
Rectal gel application of Withania somnifera root extract expounds anti-inflammatory and muco-restorative activity in TNBS-induced Inflammatory Bowel Disease
Pankaj Pawar, Suhit Gilda, Siddhesh Sharma, Suresh Jagtap, Anant Paradkar, Kakasaheb Mahadik, Prabhakar Ranjekar, Abhay Harsulkar
BMC Complementary and Alternative Medicine , 2011, DOI: 10.1186/1472-6882-11-34
Abstract: The study included (i) preparation of gel formulation from aqueous Withania somnifera root extract (WSRE), (ii) biochemical assays to determine its performance potential, (iii) testing of formulation efficacy in TNBS-induced IBD rat model, and (iv) histo-patholgical studies to assess its healing and muco-regenerative effect in IBD-induced rats. For this purpose, concentration dependant antioxidant activity of the extracts were evaluated using biochemical assays like (a) inhibition of lipid peroxidation, (b) NO scavenging, (c) H2O2 scavenging, and (d) ferric reducing power assay.The extract, at 500 μg/ml, the highest concentration tested, showed 95.6% inhibition of lipid peroxidation, 14.8% NO scavenging, 81.79% H2O2 scavenging and a reducing capacity of 0.80. The results were comparable with standard antioxidants, ascorbic acid and curcumin. WSRE treatment positively scored on histopathological parameters like necrosis, edema, neutrophil infiltration. The post treatment intestinal features showed restoration at par with the healthy intestine. In view of these results, gel formulation containing an aqueous extract of W. somnifera, prepared for rectal application was tested for its anti-inflammatory activity in TNBS-induced rat models for IBD. Commercially available anti-inflammatory drug Mesalamine was used as the standard in this assay.Dose of the rectal gel applied at 1000 mg of WSRE per kg rat weight showed significant muco-restorative efficacy in the IBD-induced rats, validated by histo-pathological studies.Withania somnifera (Dunal), also known as Ashwagandha, is an important member of family Solanaceae, utilized as a medicine for more than 2500 years in Indian medicinal classic "Ayurveda" [1]. Roots of this plant are considered most active for therapeutic purposes by virtue of significant accumulation of active constituents, withanolides [2]. Several withanolides with cyclooxygenase inhibitory and lipid peroxidation inhibitory activity were isolated from leaves
Development and Validation of Stability Indicating RP-HPLC-PDA Method for Tenatoprazole and Its Application for Formulation Analysis and Dissolution Study  [PDF]
Sunil R. Dhaneshwar, Vaijanath N. Jagtap
American Journal of Analytical Chemistry (AJAC) , 2011, DOI: 10.4236/ajac.2011.22014
Abstract: In the present study, comprehensive stress testing of tenatoprazole was carried out according to ICH guide-line Q1A (R2). Tenatoprazole was subjected to stress conditions of hydrolysis, oxidation, photolysis and neutral decomposition. Extensive degradation was found to occur in acidic, neutral and oxidative conditions. Mild degradation was observed in basic conditions. The drug is relatively stable in the solid-state. Successful separation of drug from degradation products formed under stress conditions was achieved on a Kromasil C18 column (250 mm × 4.6 mm, 5.0 μ particle size) using methanol: THF: acetate buffer (68:12:20 v/v) pH adjusted to 6.0 with acetic acid as mobile phase, flow rate was 1.0 mL●min–1 and column was maintained at 45°C. Quantification and linearity was achieved at 307 nm over the concentration range of 0.5 - 160 μg●mL–1 for tenatoprazole. The method was validated for specificity, linearity, accuracy, precision, LOD, LOQ and robustness.
Energy Efficiency Evaluation in Pumping System  [PDF]
Sharad P. Jagtap, Anand N. Pawar
Modern Mechanical Engineering (MME) , 2013, DOI: 10.4236/mme.2013.34024
Abstract:

Like 3M’s (Man, Machine and Material), energy is one of the major inputs for economic development of the country. In case of developing countries like India, the energy sector assumes critical importance in the view of the ever increasing energy needs, requiring huge investments for new power plant erection. About 85% of total primary energy need comes from fossil fuels. Particularly, oil contributes to 31% primary energy sources and the existence of it from domestic source in India may last for only about 20 years only at the current reserve to production (R/P) ratio. Similarly, coal contributes to 54% primary energy sources and may last for about 114 years at the current reserve to production (R/P) ratio. Water Pumping System is one of the major utilities in SME’s as well as power & process industry, and consumes about 10% - 15% electrical power in Industrial and Agricultural sector. As per TERI Energy data directory yearbook, Industrial sector and Agricultural sector contribute to 45% and 7% of the total energy needed respectively in India. A measurable amount of Industrial production is delivered from small and medium industries operated with inefficient equipment, where it has been difficult to implement efficiency improvements. The objective of Water Pumping System in most cases is either to transfer liquid from one reservoir to another or to circulate liquid across the heat exchanger around a system. Since worldwide, centrifugal pumps account for the majority of electricity used by pumps, this paper focuses on energy saving in centrifugal pumping system with a case study work carried out in an industry.

Socioeconomic Factors of Full Immunisation Coverage in India  [PDF]
Suresh Sharma
World Journal of Vaccines (WJV) , 2013, DOI: 10.4236/wjv.2013.33015
Abstract: The following article has been retracted due to the investigation of complaints received against it. The Editorial Board found that substantial portions of the text came from other published papers. The scientific community takes a very strong view on this matter, and the Health treats all unethical behavior such as plagiarism seriously. This paper published in Vol.3 No. 3,102-110 pages, 2013, has been removed from this site.

The Growth and the Optical, Mechanical, Dielectric and Photoconductivity Properties of a New Nonlinear Optical Crystal—L-Phenylalanine-4-nitrophenol NLO Single Crystal  [PDF]
Sagadevan Suresh
Journal of Crystallization Process and Technology (JCPT) , 2013, DOI: 10.4236/jcpt.2013.33014
Abstract: Nonlinear optical single crystals of L-phenylalanine-4-nitrophenol have been grown by the slow evaporation method. The grown crystal was subjected to the single crystal X-ray diffraction analysis, to confirm that it belongs to the monoclinic crystal structure, with space group P21. The optical transmission study reveals the transparency of the crystal in the entire visible region and the cut off wave length has been found to be 320 nm. The optical band gap is found to be 3.87 eV. The transmittance of the L-phenylalanine-4-nitrophenol crystal has been used to calculate the refractive index (n), the extinction coefficient (K) and the real (εr) and imaginary (εi) components of the dielectric constant. The mechanical behaviour of the grown crystals was studied using Vicker’s microhardness tester. The dielectric constant and dielectric loss of L-phenylalanine-4-nitrophenol are measured in the frequency range of 50 Hz to 5 MHz at different temperatures. The photoconductivity study confirms the negative photoconductive nature of the sample.

GENDER DISCRIMINATION IN INDIA AND THE ECONOMICS OF FEMALE FOETICIDE
DILIP R. JAGTAP
Golden Research Thoughts , 2013, DOI: 10.9780/22315063
Abstract: India is marching towards becoming a superpower. America has long back claimed that India is a developed country. It is a very sad thing that still there is gender discrimination in India. The women are given secondary treatment in the office and at home too. They are refused opportunities in all respects. Thesad part about discrimination is it starts even before the birth of a woman, right at the stage of fetus.India has been cursed with the serious problem of female foeticide. In many parts of the country girls are killed in the fetus stage only. A mother's womb is the most secure place, but even there a woman is now not safe. Perfectionist Aamir Khan highlighted this issue I on his program called “Satyamev Jayate” on Star TV dated 06/05/2012, this stirred the whole country. This research essay is a reaction to the same.
“Special Services Rendered By Co-operative BankAn Overview”
Kishor Nivrutti Jagtap
Golden Research Thoughts , 2012, DOI: 10.9780/22315063
Abstract: Co-operative banks in India are more than 100 years old. They came into existence with the enactment of Co-operative Credit Societies Act, 1904. Since their inception, these banks and their affiliated agencies have been playing a significant role in the socio-economic development of the country. Co-operative Banks enjoyed the monopoly till 1969. They supplement the commercial banks to deepen the financial intermediation by bringing large number of small depositors/borrowers under the formal financial sector. They form an integral part of the banking system in India. They mobilize deposits and supply agricultural and rural credit by an extensive network of their outlets (branches). They have played an important role in creating banking habits among the lower and middle-income groups and in strengthening the rural credit delivery system. Though much smaller as compared to SCBs in terms of business, they constitute an important segment of Indian Financial System. Though the banking sector reforms did not leave significant impact on the functioning of cooperative banks, cooperative banks are changing their banking facilities and products as per the changing environment. They are facing various types of problems and challenges in current competitive era; even then, they are equally important for making financial inclusion a success. It is recognized that co-operative banks and SCBs are complementary to each others. Both are important for financial inclusion. More specifically, when we see the cooperative banking structure of our country, we find that State Co-operative Banks (SCBs) are important institutions in this structure. They control, regulate and supervise the entire cooperative movement in their concerned states. They are also known as Apex Banks. So, the evaluation and appraisal of their functioning, performance and efficiency become essential.
E-BANKING-AN OVERVIEW
KISHOR NIVRUTTI JAGTAP
Golden Research Thoughts , 2013, DOI: 10.9780/22315063
Abstract: Internet banking (or E-banking) means any user with a personal computer anda browser can get connected to his bank -s website to perform any of the virtual bankingfunctions. In internet banking system the bank has a centralized database that is webenabled.All the services that the bank has permitted on the internet are displayed inmenu. Any service can be selected and further interaction is dictated by the nature ofservice. The traditional branch model of bank is now giving place to an alternativedelivery channels with ATM network. Once the branch offices of bank are interconnectedthrough terrestrial or satellite links, there would be no physical identity for any branch. Itwould a borderless entity permitting anytime, anywhere and anyhow banking.The network which connects the various locations and gives connectivity to the centraloffice within the organization is called intranet. These networks are limited toorganizations for which they are set up. SWIFT is a live example of intranet application
Effects of methanolic extract of Cuminum cyminum on total serum cholesterol in ovariectomized rats
Shirke Sarika,Jagtap Aarti
Indian Journal of Pharmacology , 2009,
Abstract:
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