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Search Results: 1 - 10 of 297498 matches for " J. Wallig "
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A high protein moderate carbohydrate diet fed at discrete meals reduces early progression of N-methyl-N-nitrosourea-induced breast tumorigenesis in rats
Christopher J Moulton, Rudy J Valentine, Donald K Layman, Suzanne Devkota, Keith W Singletary, Matthew A Wallig, Sharon M Donovan
Nutrition & Metabolism , 2010, DOI: 10.1186/1743-7075-7-1
Abstract: Breast cancer is the most common cancer in American women, with over 40,000 annual deaths and nearly 200,000 estimated new cases in 2009 [1]. Given the high prevalence of breast cancer and associated physical, social, and psychological detriments [2], reducing cancer incidence through modifiable risk factors such as nutrition is a high public health priority. Estimates suggest that cancer incidence could be reduced by ~1/3 through modifications in diet, including changes in total energy intake and diet content of fat, protein or carbohydrate [3]. With increased attention on higher protein, low carbohydrate diets for weight management, secondary effects of these diets on tumor development are important to evaluate.Some studies report that dietary protein, and particularly consumption of animal protein, is linked to increased risk of breast cancer [4,5]. However, recent large-scale evaluations have failed to identify intakes of meat, eggs, or dairy products as risk factors [6]. Conversely, epidemiological studies have reported protective effects of dietary protein on breast cancer incidence [7] and mortality [8]. A recent case-controlled study suggests that a dietary pattern including the highest relative levels of animal protein is inversely associated with breast cancer risk [9].Evidence is now accumulating that dietary carbohydrates, glycemic load, and hyperinsulinemia are associated with increased cancer risk [10,11] and mortality [12]. Higher levels of circulating and post-prandial insulin have been reported to enhance cellular proliferation and tumor development [13] through upregulation of the PI3K/Akt signal pathway which is implicated in breast cancer promotion and tumorigenesis [14]. Furthermore, insulin stimulates the ovaries to produce androgens [15], which have been linked to increased breast cancer risk [16]. To our knowledge, no studies have attempted to compare the effects of dietary protein versus carbohydrates in an experimental model of breast cance
Pelleting Diets Impairs TRAMP Prostate Carcinogenesis  [PDF]
Lauren E. Conlon, Matthew A. Wallig, John W. Erdman
Food and Nutrition Sciences (FNS) , 2017, DOI: 10.4236/fns.2017.82014
Abstract: Diets rich in soy products may reduce the risk of prostate cancer (PCa). Daidzein, the major isoflavone present in soy germ, can be metabolized by the gut microbiota into equol. The effects of daidzein and equol on PCa have not been well studied. The objective of this study was to investigate the effect of feeding 2% soy germ, 92 ppm daidzein, or 88 ppm equol diets on the progression of PCa in the transgenic adenocarcinoma of the mouse prostate (TRAMP) model. 3-week old male C57BL/6 X FVB TRAMP mice were weaned from our breeding colony and immediately acclimated to an AIN-93G control diet for one week. At 4 weeks of age, mice (n = 30 per diet group) were randomized to one of four pelleted study diets until 18 weeks of age. Unexpectedly, we did not detect any statistical differences in cancer incidence between diets. We suggest that these results are due to the physical attributes of the pelleted diets in the current study. Mice fed pelleted diets had reduced food intake and significantly decreased body weights (p < 0.001) compared to previous studies. A reduction in food intake is known to reduce cancer incidence in a number of cancer models and is likely to have contributed to the decrease in expected cancer incidence in the current study. In conclusion, we suggest that the hardness of the diets pellets could result in a decreased cancer incidence in TRAMP mice.
Psicoterapia e bioética: aproximando conceitos, aperfei?oando práticas
Ludwig, Martha Wallig Brusius;Redivo, Luciana Balestrin;Jorge, Hericka Zogbi;Müller, Marisa Campio;
Psicologia em Estudo , 2007, DOI: 10.1590/S1413-73722007000300017
Abstract: issues on the link between psychology, therapy, training and bioethics are provided and discussed. current discussion is justified due to the fact that bioethics has become an important subject in the context of contemporary technological and scientific improvements as a whole. it is thus essential to discuss bioethics in all its specialties, taking the human being as its focus and center. since psychology deals with human beings, it may be highly contribute towards the solution of dilemmas in bioethics and its importance may be highlighted within this area. consequently, the manner bioethical principles may be transposed to the psychotherapeutic process is of paramount importance. current essay reflects on the ethical dilemmas that the psychologist may face, on the use of the term of free and clear consent (tcle) in the psychotherapeutic process, professional training, among others. it shall also shed some light on less discussed issues for reflective, albeit not determinant, contributions.
Selenium, but Not Lycopene or Vitamin E, Decreases Growth of Transplantable Dunning R3327-H Rat Prostate Tumors
Brian L. Lindshield,Nikki A. Ford,Kirstie Canene-Adams,Alan M. Diamond,Matthew A. Wallig,John W. Erdman Jr
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0010423
Abstract: Lycopene, selenium, and vitamin E are three micronutrients commonly consumed and supplemented by men diagnosed with prostate cancer. However, it is not clear whether consumption of these compounds, alone or in combination, results in improved outcomes.
Localiza??o da les?o e níveis de stress em pacientes dermatológicos
Ludgwig, Martha Wallig Brusius;Oliveira, Margareth da Silva;Müller, Marisa Campio;Gon?alves, ?ngela Maria Barbosa Ferreira;
Estudos de Psicologia (Campinas) , 2008, DOI: 10.1590/S0103-166X2008000300003
Abstract: the skin is a visible organ, playing an important role in interpersonal relations, and when wounded may cause distress. stress has influences on several skin diseases just as these are stress generators. this study assessed stress and dermatological lesion sites and the association between these variables, comparing stress levels in patients with lesions on the face and/or hands and patients with lesions on other parts of the body. it was a descriptive, association-based, cross-study. the sample was made of 205 patients, who filled out the lipp's stress symptom inventory for adults, the socio-demographical data file and the lesion site file. no significant differences were found in the stress results between the groups, but the presence of stress symptoms in the majority of patients is worth highlighting, being the resistance phase and the psychological symptomatology the predominant ones. these was no significant difference in stress results between the two groups (p=0,495; p=0,873 and p=0,815). these findings corroborate the need of a biopsychosocial care to the pacientes.
Qualidade de vida e localiza??o da les?o em pacientes dermatológicos
Ludwig, Martha Wallig Brusius;Oliveira, Margareth da Silva;Muller, Marisa Campio;Moraes, Jo?o Feliz Duarte de;
Anais Brasileiros de Dermatologia , 2009, DOI: 10.1590/S0365-05962009000200007
Abstract: background - the visible aspect of skin lesions and its psychological impact interfere in the quality of life of patients. objectives- to assess the quality of life and site of dermatological lesion; to check associations between variables and compare levels of quality of life in patients with lesions on the face and/or hands and patients with lesions in parts of the body other than face and/or hands. methods - descriptive, association-based cross-sectional study. two hundred and five subjects were assessed using sf-36 generic life quality questionnaire "the medical outcomes study 36-item short-form health survey" (sf-36); the dermatology life quality index dlqi-bra, and socio-demographical and lesion site data files. results - no significant differences were observed in the results for quality of life between the two groups but the number of associations between sf-36 and dlqi-bra was higher in the group with lesions on the face and/or hands. significant differences were verified in a further detailed division into five groups. the significant difference (p=0.05) appeared between the group with lesions on the face and/or hands and the group with generalized lesions, being that the latter presented an average ranking of 114.06 compared with 69.1935 in the former group. conclusion - regardless of the site of lesion, the feeling of exposure and the damages to which the dermatological patients are exposed are similar. it seems that skin diseases bring about the feeling of exposure and embarrassment no matter which site of the body is affected because in any intimate approach there is some sort of exposure involved.
A compact ultra-clean system for deploying radioactive sources inside the KamLAND detector
T. I. Banks,S. J. Freedman,J. Wallig,N. Ybarrolaza,A. Gando,Y. Gando,H. Ikeda,K. Inoue,Y. Kishimoto,M. Koga,T. Mitsui,K. Nakamura,I. Shimizu,J. Shirai,A. Suzuki,Y. Takemoto,K. Tamae,K. Ueshima,H. Watanabe,B. D. Xu,H. Yoshida,S. Yoshida,A. Kozlov,C. Grant,G. Keefer,A. Piepke,T. Bloxham,B. K. Fujikawa,K. Han,K. Ichimura,H. Murayama,T. O'Donnell,H. M. Steiner,L. A. Winslow,D. A. Dwyer,R. D. McKeown,C. Zhang,B. E. Berger,C. E. Lane,J. Maricic,T. Miletic,M. Batygov,J. G. Learned,S. Matsuno,M. Sakai,G. A. Horton-Smith,K. E. Downum,G. Gratta,Y. Efremenko,O. Perevozchikov,H. J. Karwowski,D. M. Markoff,W. Tornow,K. M. Heeger,J. A. Detwiler,S. Enomoto,M. P. Decowski
Physics , 2014, DOI: 10.1016/j.nima.2014.09.068
Abstract: We describe a compact, ultra-clean device used to deploy radioactive sources along the vertical axis of the KamLAND liquid-scintillator neutrino detector for purposes of calibration. The device worked by paying out and reeling in precise lengths of a hanging, small-gauge wire rope (cable); an assortment of interchangeable radioactive sources could be attached to a weight at the end of the cable. All components exposed to the radiopure liquid scintillator were made of chemically compatible UHV-cleaned materials, primarily stainless steel, in order to avoid contaminating or degrading the scintillator. To prevent radon intrusion, the apparatus was enclosed in a hermetically sealed housing inside a glove box, and both volumes were regularly flushed with purified nitrogen gas. An infrared camera attached to the side of the housing permitted real-time visual monitoring of the cable's motion, and the system was controlled via a graphical user interface.
New components of the mercury’s perihelion precession  [PDF]
J. J. Smulsky
Natural Science (NS) , 2011, DOI: 10.4236/ns.2011.34034
Abstract: The velocity of perihelion rotation of Mercury's orbit relatively motionless space is computed. It is prove that it coincides with that calculated by the Newtonian interaction of the planets and of the compound model of the Sun’s rotation.
Simple General Purpose Ion Beam Deceleration System Using a Single Electrode Lens  [PDF]
J. Lopes, J. Rocha
World Journal of Engineering and Technology (WJET) , 2015, DOI: 10.4236/wjet.2015.33014
Abstract: Ion beam deceleration properties of a newly developed low-energy ion beam implantation system were studied. The objective of this system was to produce general purpose low-energy (5 to 15 keV) implantations with high current beam of hundreds of μA level, providing the most wide implantation area possible and allowing continuously magnetic scanning of the beam over the sample(s). This paper describes the developed system installed in the high-current ion implanter at the Laboratory of Accelerators and Radiation Technologies of the Nuclear and Technological Cam-pus, Sacavém, Portugal (CTN).
Constraints on velocity anisotropy of spherical systems with separable augmented densities
J. An
Physics , 2011, DOI: 10.1088/0004-637X/736/2/151
Abstract: If the augmented density of a spherical anisotropic system is assumed to be multiplicatively separable to functions of the potential and the radius, the radial function, which can be completely specified by the behavior of the anisotropy parameter alone, also fixes the anisotropic ratios of every higher-order velocity moment. It is inferred from this that the non-negativity of the distribution function necessarily limits the allowed behaviors of the radial function. This restriction is translated into the constraints on the behavior of the anisotropy parameter. We find that not all radial variations of the anisotropy parameter satisfy these constraints and thus that there exist anisotropy profiles that cannot be consistent with any separable augmented density.
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