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Search Results: 1 - 10 of 299281 matches for " J. Thompson "
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Mal/SRF Is Dispensable for Cell Proliferation in Drosophila
Barry J. Thompson
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0010077
Abstract: The Mal/SRF transcription factor is regulated by the level of G-actin in cells and has important roles in cell migration and other actin-dependent processes in Drosophila. A recent report suggests that Mal/SRF and an upstream regulator, Pico, are required for cell proliferation and tissue growth in Drosophila. I find otherwise. Mutation of Mal or SRF does not affect cell proliferation in the fly wing. Furthermore, I cannot reproduce the reported effects of Pico RNAi or Pico overexpression on body size. Nevertheless, I can confirm that overexpression of Pico or Mal causes tissue overgrowth specifically in the fly wing - where SRF is most highly expressed. My results indicate that Mal/SRF can promote tissue growth when abnormally active, but is not normally required for tissue growth during development.
Highlights of GeV gamma-ray astronomy
D. J. Thompson
Astrophysics and Space Sciences Transactions (ASTRA) , 2010, DOI: 10.5194/astra-6-59-2010
Abstract: Because high-energy gamma rays are primarily produced by high-energy particle interactions, the gamma-ray survey of the sky by the Fermi Gamma-ray Space Telescope offers a view of sites of cosmic ray production and interactions. Gamma-ray bursts, pulsars, pulsar wind nebulae, binary sources, and Active Galactic Nuclei are all phenomena that reveal particle acceleration through their gamma-ray emission. Diffuse Galactic gamma radiation, Solar System gamma-ray sources, and energetic radiation from supernova remnants are likely tracers of high-energy particle interactions with matter and photon fields. This paper will present a broad overview of the constantly changing sky seen with the Large Area Telescope (LAT) on the Fermi spacecraft.
Grand challenges in the physics of the sun and sun-like stars
Michael J. Thompson
Frontiers in Astronomy and Space Sciences , 2014, DOI: 10.3389/fspas.2014.00001
Helioseismology over the solar cycle
M. J. Thompson
Physics , 2010,
Abstract: Helioseismology has produced unprecedented measurements of the Sun's internal structure and dynamics over the past 25 years. Much of this work has been based on global helioseismology. Now local helioseismology too is showing its great promise. This review summarizes very briefly the principal global results that may be relevant to an understanding of the origins of solar magnetism. Recent results regarding the variation of frequencies over the solar cycle and the temporal variations of subsurface flows are briefly summarized.
Reaction mechanisms of pair transfer
Ian J. Thompson
Physics , 2012,
Abstract: The mechanisms of nuclear transfer reactions are described for the transfer of two nucleons from one nucleus to another. Two-nucleon overlap functions are defined in various coordinate systems, and their transformation coefficients given between coordinate systems. Post and prior couplings are defined for sequential transfer mechanisms, and it is demonstrated that the combination of `prior-post' couplings avoids non-orthogonality terms, but does not avoid couplings that do not have good zero-range approximations. The simultaneous and sequential mechanisms are demonstrated for the $^{124}$Sn(p,t)$^{122}$Sn reaction at 25 MeV using shell-model overlap functions. The interference between the various simultaneous and sequential amplitudes is shown.
Measurements of alpha_s from hadronic event shapes in e+e- annihilation
J. C. Thompson
Physics , 1998,
Abstract: New studies of hadronic event shape observables in e+ e- collisions between 13 and 183 GeV CM energy have enabled the running of alpha_s to be confirmed and the validity of non-perturbative power-law corrections to be investigated. A more precise value of alpha_s(M_Z) with reduced theoretical errors has been reported from fitting 18 oriented event shape distributions measured in one experiment at the Z.
Gamma Radiation from PSR B1055-52
D. J. Thompson
Physics , 1998, DOI: 10.1086/307083
Abstract: The telescopes on the Compton Gamma Ray Observatory (CGRO) have observed PSR B1055-52 a number of times between 1991 and 1998. From these data, a more detailed picture of the gamma radiation from this source has been developed, showing several characteristics which distinguish this pulsar: the light curve is complex; there is no detectable unpulsed emission; the energy spectrum is flat, with no evidence of a sharp high-energy cutoff up to >4 GeV. Comparisons of the gamma-ray data with observations at longer wavelengths show that no two of the known gamma-ray pulsars have quite the same characteristics; this diversity make s interpretation in terms of theoretical models difficult.
Probing the Structure of Halo Nuclei
I. J. Thompson
Physics , 1997, DOI: 10.1088/0954-3899/23/10/011
Abstract: Our understanding of halo nuclei has so far relied on high-energy scattering and reactions, but a number of uncertainties remain. I discuss in general terms the new range of observables which will be measured by experiments around the Coulomb barrier, and how some details of the reaction mechanisms still need to be clarified.
Space Detectors for Gamma Rays (100 MeV - 100 GeV): from EGRET to Fermi LAT
David J. Thompson
Physics , 2015,
Abstract: The design of spaceborne high-energy (E>100 MeV) gamma-ray detectors depends on two principal factors: (1) the basic physics of detecting and measuring the properties of the gamma rays; and (2) the constraints of operating such a detector in space for an extended period. Improvements in technology have enabled major advances in detector performance, as illustrated by two successful instruments, EGRET on the Compton Gamma Ray Observatory and LAT on the Fermi Gamma-ray Space Telescope.
Advances in Shell Buckling: Theory and Experiments
J. Michael T. Thompson
Physics , 2014, DOI: 10.1142/S0218127415300013
Abstract: In a recent feature article in this journal, co-authored by Gert van der Heijden, I described the static-dynamic analogy and its role in understanding the localized post-buckling of shell-like structures, looking exclusively at integrable systems. We showed the true significance of the Maxwell energy criterion load in predicting the sudden onset of 'shock sensitivity' to lateral disturbances. The present paper extends the survey to cover non-integrable systems, such as thin compressed shells. These exhibit spatial chaos, generating a multiplicity of localized paths (and escape routes) with complex snaking and laddering phenomena. The final theoretical contribution shows how these concepts relate to the response and energy barriers of an axially compressed cylindrical shell. After surveying NASA's current shell-testing programme, a new non-destructive technique is proposed to estimate the 'shock sensitivity' of a laboratory specimen that is in a compressed meta-stable state before buckling. A probe is used to measure the nonlinear load-deflection characteristic under a rigidly applied lateral displacement. Sensing the passive resisting force, it can be plotted in real time against the displacement, displaying an equilibrium path along which the force rises to a maximum and then decreases to zero: having reached the free state of the shell that forms a mountain-pass in the potential energy. The area under this graph gives the energy barrier against lateral shocks. The test is repeated at different levels of the overall compression. If a symmetry-breaking bifurcation is encountered on the path, computer simulations show how this can be supressed by a controlled secondary probe tuned to deliver zero force on the shell.
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