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Search Results: 1 - 10 of 299120 matches for " J. Nielsen "
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On Some Numbers Related to the Erdös-Szekeres Theorem  [PDF]
Mark J. Nielsen, William Webb
Open Journal of Discrete Mathematics (OJDM) , 2013, DOI: 10.4236/ojdm.2013.33030
Abstract:

A crossing family of segments is a collection of segments each pair of which crosses. Given positive integers j and k,a(j,k) grid is the union of two pairwise-disjoint collections of segments (with j and k members, respectively) such that each segment in the first collection crosses all members of the other. Let c(k) be the least integer such that any planar set of c(k) points in general position generates a crossing family of k segments. Also let #(j,k) be the least integer such that any planar set of #(j,k) points in general position generates a (j,k)-grid. We establish here the facts 9≤c(3)≤16 and #(1,2)=8.


Corn and Soybean Responses to Two Tillage Systems in a Cool Growing Season  [PDF]
Jesper K. V. Nielsen, Howard J. Woodard
Open Journal of Soil Science (OJSS) , 2015, DOI: 10.4236/ojss.2015.58016
Abstract: A field study in 2014 documented corn and soybean biomass and nutrient responses between conventional-till and no-till tillage systems at Beresford, SD during cooler than normal weather conditions with adequate soil moisture. The overall study was established in 1992. Each treatment plot was monitored weekly from June to August for soil moisture, temperature, and plant growth stages. Biomass was harvested during and at the end of the growing season for yield and nutrient content. Soil moisture measured throughout the early and middle part of the growing season was determined to be sufficient for crop growth, since precipitation was much greater than normal in June (33.2 cm). However, air temperature was below normal early in the growing season and lowered Growing Degree Days (939°C) compared to the 30-year average (139°C). Soil temperatures (5 cm depth) were not significant between tillage treatments in the corn plots during the growing season for 12 observation dates (range 16.3°C - 28.0°C). Plant growth was not significantly different between tillage treatments, reflecting the lack of soil temperature differences (5 cm depth) between tillage treatments. The mid-season plant tissue and crop residue at harvest nutrient content (P, K, and Zn) were not significant between tillage treatments. Corn grain yields were 10.3 T·ha-1 and 10.1 T·ha-1 for conventional tillage and no-till, respectively. Soybean grain yields were 3.9 T·ha-1?and 3.3 T·ha-1 for conventional tillage and no-till, respectively. These results would more than likely have been
Antisense Gene Silencing: Therapy for Neurodegenerative Disorders?
Troels T. Nielsen,J?rgen E. Nielsen
Genes , 2013, DOI: 10.3390/genes4030457
Abstract: Since the first reports that double-stranded RNAs can efficiently silence gene expression in C . elegans, the technology of RNA interference (RNAi) has been intensively exploited as an experimental tool to study gene function. With the subsequent discovery that RNAi could also be applied to mammalian cells, the technology of RNAi expanded from being a valuable experimental tool to being an applicable method for gene-specific therapeutic regulation, and much effort has been put into further refinement of the technique. This review will focus on how RNAi has developed over the years and how the technique is exploited in a pre-clinical and clinical perspective in relation to neurodegenerative disorders.
Low-carbohydrate diet in type 2 diabetes. Stable improvement of bodyweight and glycemic control during 22 months follow-up
J?rgen Nielsen, Eva Joensson
Nutrition & Metabolism , 2006, DOI: 10.1186/1743-7075-3-22
Abstract: We previously reported that a 20 % carbohydrate diet was significantly superior to a 55–60 % carbohydrate diet with regard to bodyweight and glycemic control in 2 non-randomised groups of obese diabetes patients observed closely over 6 months. The effect beyond 6 months of reduced carbohydrate has not been previously reported. The objective of the present study, therefore, was to determine to what degree the changes among the 16 patients in the low-carbohydrate diet group at 6-months were preserved or changed 22 months after start, even without close follow-up. In addition, we report that, after the 6 month observation period, two thirds of the patients in the high-carbohydrate changed their diet. This group also showed improvement in bodyweight and glycemic control.Retrospective follow-up of previously studied subjects on a low carbohydrate diet.The mean bodyweight at the start of the initial study was 100.6 ± 14.7 kg. At six months it was 89.2 ± 14.3 kg. From 6 to 22 months, mean bodyweight had increased by 2.7 ± 4.2 kg to an average of 92.0 ± 14.0 kg. Seven of the 16 patients (44%) retained the same bodyweight from 6 to 22 months or reduced it further; all but one had lower weight at 22 months than at the beginning. Initial mean HbA1c was 8.0 ± 1.5 %. After 6 and 12 months it was 6.6 ± 1.0 % and 7.0 ± 1.3 %, respectively. At 22 months, it was still 6.9 ± 1.1 %.Advice on a 20 % carbohydrate diet with some caloric restriction to obese patients with type 2 diabetes has lasting effect on bodyweight and glycemic control.We previously reported that 16 obese patients with type 2 diabetes, who were advised to lower their carbohydrate intake to 20 %, over 6 months achieved significantly better control of hyperglycemia and bodyweight than a control group of similar patients (n = 15), advised to follow the official dietary guidelines where 55–60 % carbohydrate is recommended [1]. We have now reviewed the clinical charts after 22 months and present the data for the patients.
Christian Theodor Vaupell, a Danish 19th century naturalist and a pioneering developer of the Quaternary geoscience
J. K. Nielsen,S. Helama
History of Geo- and Space Sciences (HGSS) , 2012, DOI: 10.5194/hgss-3-143-2012
Abstract: Christian Theodor Vaupell (1821–1862) was a Danish scholar with pioneering investigations particularly on the late Quaternary development of bog forests, but also microscopy of plant anatomy and vegetative reproduction. His studies contributed to the early scientific thinking of the Quaternary environmental changes. Before his academic efforts, he had already survived the war between Prussia and Denmark albeit he became severely wounded and his left arm was amputated. The drama of his academic efforts, on the other hand, lies in the more or less suspicious dispute of his first doctoral thesis and his dismissal from the academic world during the following years. At the same time, he earned praise for his first thesis (never accepted as thesis but published as a regular book) from abroad; he was also able to attract private foundations for financial support of his scientific work. Following the enthusiasm of his time, Vaupell became attracted to the pine megafossils known to have been preserved in the bogs in north-west Europe. The megafossils led him to study not only the life systems of the ancient and modern bog forests but also their associations with Earth processes. As an interesting detail of his research, Vaupell made compound interpretations on the occurrence of megafossil stumps and their tree-ring growth patterns. In the course of the 20th century, Vaupell's studies have been cited as a general reference of post-glacial vegetation change and plant succession rather than clearly pioneering investigations of palaeoecology, an angle that we would like put into a contrasting perspective. To do so, we provide a brief portrait of Christian Vaupell and his research career. In conclusion, we wish to emphasize the comprehensiveness of Vaupell's views on the late Quaternary vegetation changes and the role of plant succession in that development.
Soluble interleukin-2 receptors in ulcerative colitis
O. H. Nielsen,J. Brynskov
Mediators of Inflammation , 1993, DOI: 10.1155/s096293519300016x
Abstract:
Deltagerorienteringen i undervisningen af MPA studerende – refleksioner og praksis
J.C. Ry Nielsen
Dansk Universitetspaedagogisk Tidsskrift , 2008,
Abstract: Praksisrelation er en vigtig bestanddel af p dagogikken p Copenhagen Business School (CBS). P MPA uddannelsen er vi privilegerede i denne sammenh ng, fordi vore deltagere med en gennemsnitsalder p over 40 r selv m der op med megen erfaring. Vores opgave som undervisere og designere af uddannelsen er at skabe rammerne for, at deltagernes erfaringer kan bringes i spil ud fra mottoet fra n rhed til distance – og tilbage igen . Forfatteren gengiver b de de mere overordnede overvejelser, man har gjort sig p uddannelsen, og en r kke af de mere praktiske tiltag, der har v ret sat i v rk.
Failure to Demonstrate That Playing Violent Video Games Diminishes Prosocial Behavior
Morgan J. Tear, Mark Nielsen
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0068382
Abstract: Background Past research has found that playing a classic prosocial video game resulted in heightened prosocial behavior when compared to a control group, whereas playing a classic violent video game had no effect. Given purported links between violent video games and poor social behavior, this result is surprising. Here our aim was to assess whether this finding may be due to the specific games used. That is, modern games are experienced differently from classic games (more immersion in virtual environments, more connection with characters, etc.) and it may be that playing violent video games impacts prosocial behavior only when contemporary versions are used. Methods and Findings Experiments 1 and 2 explored the effects of playing contemporary violent, non-violent, and prosocial video games on prosocial behavior, as measured by the pen-drop task. We found that slight contextual changes in the delivery of the pen-drop task led to different rates of helping but that the type of game played had little effect. Experiment 3 explored this further by using classic games. Again, we found no effect. Conclusions We failed to find evidence that playing video games affects prosocial behavior. Research on the effects of video game play is of significant public interest. It is therefore important that speculation be rigorously tested and findings replicated. Here we fail to substantiate conjecture that playing contemporary violent video games will lead to diminished prosocial behavior.
Separable states are more disordered globally than locally
M. A. Nielsen,J. Kempe
Physics , 2000, DOI: 10.1103/PhysRevLett.86.5184
Abstract: A remarkable feature of quantum entanglement is that an entangled state of two parties, Alice (A) and Bob (B), may be more disordered locally than globally. That is, S(A) > S(A,B), where S(.) is the von Neumann entropy. It is known that satisfaction of this inequality implies that a state is non-separable. In this paper we prove the stronger result that for separable states the vector of eigenvalues of the density matrix of system AB is majorized by the vector of eigenvalues of the density matrix of system A alone. This gives a strong sense in which a separable state is more disordered globally than locally and a new necessary condition for separability of bipartite states in arbitrary dimensions. We also investigate the extent to which these conditions are sufficient to characterize separability, exhibiting examples that show separability cannot be characterized solely in terms of the local and global spectra of a state. We apply our conditions to give a simple proof that non-separable states exist sufficiently close to the completely mixed state of $n$ qudits.
Antibody administration in experimental influenza increases survival and enhances the effect of oseltamivir  [PDF]
Brit N. J. Pourroy, Hans J?rn Kolmos, Lars P. Nielsen
Health (Health) , 2012, DOI: 10.4236/health.2012.430143
Abstract: Anti-viral chemotherapy plays an important part in treating and preventing influenza illness. However, its effectiveness in severe infections can be debated and a reoccurring problem is the emergence of resistant virus. Passive immunisation has for a long time been and is still used for prophylaxis and treatment of a number of infectious diseases. In this experimental study anti-influenza antibodies were passively administrated to mice, subsequently they were infected with influenza virus and treated with oseltamivir. The aim was to investigate, if anti-influenza antibodies influenced the out come of oseltamivir treatment and development of resistance towards oseltamivir. We show, that oseltamivir alone was not able to effectively prevent a fatal outcome, but that oseltamivir administered together with a limited amount of antibodies, resulted in improvement of the clinical condition of the mice. The results also showed that a higher dosage of antibodies alone were able to protect the mice from a lethal dose of virus. These findings suggest that the effectiveness of oseltamivir depends on the host’s immune response to the influenza virus, and that that passive immunization is an option that should be considered in the in control of influenza.
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