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Search Results: 1 - 10 of 297656 matches for " J. Kawada "
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Improvements in the measurement of stool decay-accelerating factor in the detection of colorectal cancer.
Ohya S,Mizuno M,Kawada M,Nasu J
Acta Medica Okayama , 2002,
Abstract: We have previously developed an enzyme-linked immunosorbent assay (ELISA) to measure stool decay-accelerating factor (DAF) and found that stool DAF concentrations were significantly elevated in patients with colorectal cancer, suggesting that the measurement of stool DAF may be valuable for the detection of colorectal cancer. In order to refine the assay for the measurement of stool DAF, we investigated 1) effects of centrifugation of stool samples, 2) effects of detergents, and 3) adequate combination of various anti-DAF monoclonal antibodies for the ELISA system using only monoclonal antibodies. We found that high-speed centrifugation could be omitted and that only the removal of large undigested food residues by centrifugation of short duration in a low-speed benchtop microcentrifuge sufficed to adequately prepare the stool samples. Addition of 2 detergents, octyl beta-glucoside and sodium deoxycholate, known to solubilize glycosyl-phosphatidylinositol-anchored proteins such as DAF, did not influence stool DAF values. By using 2 mouse anti-DAF monoclonal antibodies (clone 4F11 and 1C6), we were able to achieve a stable ELISA for the measurement of stool DAF using a uniform source of antibodies. The results should allow us to consistently apply the DAF assay for routine use in the detection of colorectal cancer.
Pictorial key for females of Decevania Huben (Hymenoptera, Evaniidae) and description of a new species
Ricardo Kawada
ZooKeys , 2011, DOI: 10.3897/zookeys.116.1473
Abstract: Decevania Huben currently comprises 13 species, the females of which are known for only four. Herein an additional Neotropical Decevania is newly described: Decevania feitosai Kawada, sp. n. from Colombia. The description and identification key were made using the DELTA program. A pictorial key to females of Decevania is provided. Anatomical terminology follows the Hymenoptera Anatomy Ontology project with an atlas for terminologies used for recognition of Decevania species. The distribution maps can be accessed in Google Maps or through of Dryad (repository of data).
Molecular mechanism of stellate cell activation and therapeutic strategy for liver fibrosis
Kawada Norifumi
Comparative Hepatology , 2004, DOI: 10.1186/1476-5926-2-s1-s3
Abstract:
Dermoscopic Appearances in the Superficial and Deep Type of Infantile Hemangioma  [PDF]
Muneharu Miyake, Naoki Oiso, Akira Kawada
Journal of Cosmetics, Dermatological Sciences and Applications (JCDSA) , 2012, DOI: 10.4236/jcdsa.2012.23038
Abstract: Infantile hemangioma is clinically classified as superficial, superficial and deep (mixed), and deep. Dermoscopy can be used for analyzing vascular structure and for classifying infantile hemangioma. Here, we focus on vascular features of the superficial and deep type of infantile hemangioma and show the three characteristic dermoscopic forms, mostly reddish, diffuse reddish, and cerebriform reddish.
Reed Nevus (Pigmented Spindle Cell Nevus) in an 11-Month-Old Japanese Infant  [PDF]
Miyuki Fujita, Naoki Oiso, Akira Kawada
Journal of Cosmetics, Dermatological Sciences and Applications (JCDSA) , 2012, DOI: 10.4236/jcdsa.2012.24045
Abstract: Reed nevus (pigmented spindle cell nevus) is a nevus with the histopathological features of abundant melanin, monomorphic spindle-epithelioid melanocytes, spindle cell nests confined within the epidermis and papillary dermis, and occasional upward interepidermal progression of melanocytes. Here, we reported an unusual case of Reed nevus in an 11-month-old Japanese male infant. Infantile Reed nevus should be included as a differential diagnosis for nevus pigmentosus in infancy.
Concomitant Occurrence of Segmental Neurofibromatosis and Lung Adenocarcinoma  [PDF]
Ryoko Morita, Naoki Oiso, Akira Kawada
Journal of Cosmetics, Dermatological Sciences and Applications (JCDSA) , 2012, DOI: 10.4236/jcdsa.2012.24050
Abstract: Neurofibromatosis type 1 (NF1) caused by a loss-of functional mutation in NF1 encoding neurofibromin is an autosomal dominant disorder characterized by café-au-lait spots, neurofibromas, intertriginous freckles, and Lisch nodules. Segmental neurofibromatosis (SN) represents a postzygotic mutation and loss of heterozygosity in neurofibromin. SN occurring in the elder persons may be associated with internal malignant tumors. Here, we reported a case of 58-year-old woman with concomitant occurrence of SN and lung adenocarcinoma. The onset of SN in aged persons would be a sign of concomitant occurrence of internal malignant tumors.
Early Pulsed Dye Laser Treatment for Infantile Hemangiomas: An Open Study for 50 Japanese Infancies  [PDF]
Hideki Endo,Naoki Oiso,Akira Kawada
Journal of Cosmetics, Dermatological Sciences and Applications (JCDSA) , 2013, DOI: 10.4236/jcdsa.2013.33033
Abstract: Infantile hemangiomas, occurring at birth or during the first weeks of life, are benign vascular tumors with an initial proliferative phase and a later involutional phase. The massive proliferation on the key regions and unpredicted regression may threaten life. Thus, early management of infantile hemangiomas is necessary for affected infancies. Recent studies showed that propranolol for infantile hemangiomas had high efficacy for disappearance or reduction of infantile hemangiomas. However, a most recent study demonstrated existence of propranolol-resistant infantile hemangiomas. Therefore, we retrospectively evaluated efficacy of established early pulsed dye laser treatment for infantile hemangiomas in the 50 Japanese infancies which were applied in the period from 2000 to 2005, because our series included from the plaque subtype to the more proliferative tumor subtype. High efficacy in both subtypes suggests that early pulsed dye laser treatment can still be included as the first option for the mixed type of infantile hemangiomas and that pulsed dye laser treatment may be useful as the second line for the propranolol-resistant mixed type of infantile hemangiomas.
Early Pulsed Dye Laser Treatment for Infantile Hemangiomas: An Open Study for 50 Japanese Infancies  [PDF]
Hideki Endo, Naoki Oiso, Akira Kawada
Journal of Cosmetics, Dermatological Sciences and Applications (JCDSA) , 2013, DOI: 10.4236/jcdsa.2013.33033
Abstract:

Infantile hemangiomas, occurring at birth or during the first weeks of life, are benign vascular tumors with an initial proliferative phase and a later involutional phase. The massive proliferation on the key regions and unpredicted regression may threaten life. Thus, early management of infantile hemangiomas is necessary for affected infancies. Recent studies showed that propranolol for infantile hemangiomas had high efficacy for disappearance or reduction of infantile hemangiomas. However, a most recent study demonstrated existence of propranolol-resistant infantile hemangiomas. Therefore, we retrospectively evaluated efficacy of established early pulsed dye laser treatment for infantile hemangiomas in the 50 Japanese infancies which were applied in the period from 2000 to 2005, because our series included from the plaque subtype to the more proliferative tumor subtype. High efficacy in both subtypes suggests that early pulsed dye laser treatment can still be included as the first option for the mixed type of infantile hemangiomas and that pulsed dye laser treatment may be useful as the second line for the propranolol-resistant mixed type of infantile hemangiomas.

Observations of [C II] 158 micron Line and Far-infrared Continuum Emission toward the High-latitude Molecular Clouds in Ursa Major
Hideo Matsuhara,Masahiro Tanaka,Yoshinori Yonekura,Yasuo Fukui,Mitsunobu Kawada,James. J. Bock
Physics , 1997, DOI: 10.1086/304895
Abstract: We report the results of a rocket-borne observation of [C II] 158\micron line and far-infrared continuum emission at 152.5\micron toward the high latitude molecular clouds in Ursa Major. We also present the results of a follow-up observation of the millimeter ^{12}CO J=1-0 line over a selected region observed by the rocket-borne experiment. We have discovered three small CO cloudlets from the follow-up ^{12}CO observations. We show that these molecular cloudlets, as well as the MBM clouds(MBM 27/28/29/30), are not gravitationally bound. Magnetic pressure and turbulent pressure dominate the dynamic balance of the clouds. After removing the HI-correlated and background contributions, we find that the [C II] emission peak is displaced from the 152.5\micron and CO peaks, while the 152.5\micron continuum emission is spatially correlated with the CO emission. We interpret this behavior by attributing the origin of [C II] emission to the photodissociation regions around the molecular clouds illuminated by the local UV radiation field. We also find that the ratio of the molecular hydrogen column density to velocity-integrated CO intensity is 1.19+-0.29x10^{20} cm^{-2} (K kms^{-1})^{-1} from the FIR continuum and the CO data. The average [C II] /FIR intensity ratio over the MBM clouds is 0.0071, which is close to the all sky average of 0.0082 reported by the FIRAS on the COBE satellite. The average [C II]/CO ratio over the same regions is 420, which is significantly lower than that of molecular clouds in the Galactic plane.
A Search for Near-Infrared Emission From the Halo of NGC 5907 at Radii of 10 kpc to 30 kpc
S. A. Yost,J. J. Bock,M. Kawada,A. E. Lange,T. Matsumoto,K. Uemizu,T. Watabe,T. Wada
Physics , 1999, DOI: 10.1086/308871
Abstract: We present a search for near-infrared (3.5-5 micron) emission from baryonic dark matter in the form of low-mass stars and/or brown dwarfs in the halo of the nearby edge-on spiral galaxy NGC 5907. The observations were made using a 256 by 256 InSb array with a pixel scale of 17" at the focus of a liquid-helium-cooled telescope carried above the Earth's atmosphere by a sounding rocket. In contrast to previous experiments which have detected a halo around NGC 5907 in the V, R, I, J and K bands at galactic radii 6kpc < r < 10kpc, our search finds no evidence for emission from a halo at 10kpc < r < 30kpc. Assuming a halo mass density scaling as r^(-2), which is consistent with the flat rotation curves that are observed out to radii of 32kpc, the lower limit of the mass-to-light ratio at 3.5-5 microns for the halo of NGC 5907 is 250 (2 sigma) in solar units. This is comparable to the lower limit we have found previously for NGC 4565 (Uemizu et al. 1998). Based on recent models, our non-detection implies that hydrogen- burning stars contribute < 15% of the mass of the dark halo of NGC 5907. Our results are consistent with the previous detection of extended emission at r < 10kpc if the latter is caused by a stellar population that has been ejected from the disk because of tidal interactions. We conclude that the dark halo of NGC 5907, which is evident from rotation curves that extend far beyond 10kpc, is not comprised of hydrogen burning stars.
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