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Search Results: 1 - 10 of 297468 matches for " J. Fabritius "
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Imperfect Implementation of an Early Warning Scoring System in a Danish Teaching Hospital: A Cross-Sectional Study
Mark Niegsch, Maria Louise Fabritius, Jacob Anh?j
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0070068
Abstract: Background In 2007, the initiation of a patient safety campaign led to the introduction of Ward Observational Charts (WOC) and Medical Early Warning Score (MEWS) at Naestved Regional Hospital. This included systematic measuring of vital signs of all patients in order to prevent patient deterioration and assure timely and correct initiation of treatment. The aim of this study was to assess to what degree WOC guidelines being followed by ward staff. Design and Setting A 7-day prospective, observational, randomised, cross-sectional, point prevalence study of WOC guideline compliance in hospitalised patients on twelve wards at Naestved Hospital. Results The study included 132 patients. Of these, 58% had been observed and managed correctly according to WOC guidelines. 77% had all MEWS elements recorded by staff. One patient had no MEWS elements recorded. Only 38% of patients with abnormal MEWS were correctly escalated by nursing staff. Staff was aware of the abnormal MEWS observed by investigator in 60% of the patients. Each element of WOC was on average recorded by staff in 90% of the patients. Conclusion At the time of our study, the long-term implementation of WOC guidelines has not been completed satisfactorily. The lacking component in the implementation of MEWS and WOC is the documentation of action taken upon finding an abnormal value. Unsuccessful implementation could result in incorrect results from evaluation of an early warning system. We suggest a redesign of the training programme to educate staff in recognising and caring for critically ill patients at Naestved Hospital.
Effect of Blast Furnace Sludge (BFS) Characteristics on Suitable Recycling Process Determining  [PDF]
Mamdouh Omran, Timo Fabritius, Timo Paananen
Journal of Minerals and Materials Characterization and Engineering (JMMCE) , 2017, DOI: 10.4236/jmmce.2017.54016
Abstract: The present study aims to give a detailed characterization of blast furnace sludge (BFS) by using different techniques, in order to determine the most effective recycling method to recover valuable metals from this waste. BFS is composed mainly of hematite, as its iron-bearing phase, and carbon, in addition to fractions of silicate and carbonate materials. The studied BFS shows relatively high contents of iron (Fe) (390 g.kg-1), and carbon (C) (290 g.kg-1), due to abundance of hematite and coke, while the concentration of zinc (Zn) (2.5 g.kg-1) is low. The XRD analyses indicated that, hematite is more concentrated in the fine fraction (<20 μm), while the coarser fraction (90 - 250 μm) is dominated by calcite, quartz and X-ray amorphous coke. SEM-EDX analyses confirmed that particles rich in iron and zinc were detected in the fine fraction (<20 μm) of the sludge. Due to high Fe and C content in BFS, it can be utilized as self-reducing material and briquetting represent a potential method for recycling of blast furnace sludge.
Fe-Si particles on the surface of blast furnace coke
Stanislav S. Gornostayev,Eetu-Pekka Heikkinen,Jyrki J. Heino,Timo M. J. Fabritius
- , 2015, DOI: https://doi.org/10.1007/s12613-015-1124-9
Abstract: This study investigates the surface of unpolished samples of blast furnace (BF) coke drilled from the tuyere zone, which hosts Fe-Si particles (mostly Fe3Si) that vary in size, shape, depth of submersion (penetration) into the coke matrix, and contact features with the surface. Based on the shape of the particles and the extent of their contact with the coke matrix, they have been grouped into three major types: (I) sphere-like droplets with limited contact area, (II) semi-spheres with a larger contact area, and (III) irregular segregations with a spherical surface, which exhibit the largest contact area among the three types of particles. Considering the ratio between the height (h) of the particles and half of their length at the surface level (l) along the cross-section, these three types can be characterized as follows: (I) h > l, (II) h ≈ l, and (III) h < l. All the three types of particles can be found near each other. The shape and the extent of the contact depend on the degree of penetration of the material into the matrix, which is a function of the composition of the particles. Type (I) particles were initially saturated with Si at an earlier stage and, for that reason, they can react less with carbon in the coke matrix than type (II) and (III), thereby moving faster through the coke cone. Thermodynamic calculations have shown that the temperature interval of 1250–1300°C can be considered the starting point for Si entering into molten iron under quartz-dominated coke ash. Accordingly, the initial pick-up of Si by molten iron can be assumed to be mineral-related. In terms of BF practice, better conditions for sliding Fe-Si droplets through the coke cone are available when they come into contact with free SiO2 concentrated into small grains, and when the SiO2/ΣMe x O y mass ratio in the coke ash is high.
Towards More Sustainable Ironmaking—An Analysis of Energy Wood Availability in Finland and the Economics of Charcoal Production
Hannu Suopaj?rvi,Timo Fabritius
Sustainability , 2013, DOI: 10.3390/su5031188
Abstract: Replacement of fossil carbon by renewable biomass-based carbon is an effective measure to mitigate CO 2 emission intensity in the blast furnace ironmaking process. Depending on the substitution rate of fossil fuels, the required amount of biomass can be substantial. This raises questions about the availability of biomass for multiple uses. At the same time, the economic competitiveness of biomass-based fuels in ironmaking applications should also be a key consideration. In this assessment, availability of energy wood, i.e., logging residues, small-diameter wood and stumps, in Finland is discussed. Since biomass must be submitted to a thermochemical process before use in a blast furnace, the paper describes the production chain, from biomass to charcoal, and economics related to each processing step. The economics of biomass-based reducing agents is compared to fossil-based ones by taking into account the effect of European Union Emissions Trading System (EU ETS). The assessment reveals that there would be sufficient amounts of energy wood available for current users as well as for ironmaking. At present, the economics of biomass-based reducing agents in ironmaking applications is unfavorable. High CO 2 emission allowance prices would be required to make such a scheme competitive against fossil-based reducing agents at current fuel prices.
Tests of cosmic ray radiography for power industry applications
J. M. Durham,E. Guardincerri,C. L. Morris,J. Bacon,J. Fabritius,S. Fellows,K. Plaud-Ramos,D. Poulson,J. Renshaw
Physics , 2015,
Abstract: In this report, we assess muon multiple scattering tomography as a non-destructive inspection technique in several typical areas of interest to the nuclear power industry, including monitoring concrete degradation, gate valve conditions, and pipe wall thickness. This work is motivated by the need for radiographic methods that do not require the licensing, training, and safety controls of x-rays, and by the need to be able to penetrate considerable overburden to examine internal details of components that are otherwise inaccessible, with minimum impact on industrial operations. In some scenarios, we find that muon tomography may be an attractive alternative to more typical measurements.
Analyse des cannabino des par spectrométrie de masse en mode tandem Analysis of cannabinoids by tandem mass spectrometry
Fabritius Marie,Staub Christian,Giroud Christian
Annales de Toxicologie Analytique , 2011, DOI: 10.1051/ata/2011104
Abstract: Depuis quelques années, la spectrométrie de masse en tandem (MS/MS) ne cesse de gagner du terrain comme méthode d’analyse en toxicologie forensique, notamment pour le dosage des cannabino des. Couplée à la chromatographie liquide (LC) ou gazeuse (GC), elle permet l’identification fiable et le dosage rapide du THC, de son précurseur acide, et de ses principaux métabolites, y compris les glucuronides. Au cours de ces dix dernières années, un nombre significatif de publications sont parues sur ce sujet. L’objectif de cet article est de passer en revue les analyses par spectrométrie de masse en tandem des cannabino des dans diverses matrices biologiques. In recent years, tandem mass spectrometry (MS/MS) is gaining ground as a reference method of analysis in clinical and forensic toxicology, especially for the determination of cannabinoids. Coupled to liquid chromatography (LC) or gas chromatography (GC), it allows the definitive identification and rapid determination of THC, its acid precursor, and its major metabolites, including the glucuronides. During the past decade, several methods of analysis of cannabinoids in different matrices have appeared on this subject. The aim of this paper is to review the analysis of cannabinoids by tandem mass spectrometry methods in various biological matrices.
Finite temperature ordering of dilute graphene antiferromagnets
Thomas Fabritius,Nicolas Laflorencie,Stefan Wessel
Physics , 2010, DOI: 10.1103/PhysRevB.82.035402
Abstract: We employ large-scale quantum Monte Carlo simulations to study the magnetic ordering transition among dilute magnetic moments randomly localized on the graphene honeycomb lattice, induced by long-ranged RKKY interactions at low charge carrier concentration. In this regime the effective exchange interactions are ferromagnetic within each sublattice, and antiferromagnetic between opposite sublattices, with an overall cubic decay of the interaction strength with the separation between the moments. We verify explicitly, that this commensurability leads to antiferromagnetic order among the magnetic moments below a finite transition temperature in this two-dimensional system. Furthermore, the ordering temperature shows a crossover in its power-law scaling with the moments' dilution from a low- to a high-concentration regime.
Detecting Special Nuclear Material Using Muon-Induced Neutron Emission
E. Guardincerri,J. D. Bacon,K. Borodzin,J. M. Durham,J. M. Fabritius II,A. Hecht,E. C. Milner,H. Miyadera,C. L. Morris,J. O. Perry,D. Poulson
Physics , 2014, DOI: 10.1016/j.nima.2015.03.070
Abstract: The penetrating ability of cosmic ray muons makes them an attractive probe for imaging dense materials. Here, we describe experimental results from a new technique that uses neutrons generated by cosmic-ray muons to identify the presence of special nuclear material (SNM). Neutrons emitted from SNM are used to tag muon-induced fission events in actinides and laminography is used to form images of the stopping material. This technique allows the imaging of SNM-bearing objects tagged using muon tracking detectors located above or to the side of the objects, and may have potential applications in warhead verification scenarios. During the experiment described here we did not attempt to distinguish the type or grade of the SNM.
Cognitive functioning in opioid-dependent patients treated with buprenorphine, methadone, and other psychoactive medications: stability and correlates
Pekka Rapeli, Carola Fabritius, Hely Kalska, Hannu Alho
BMC Pharmacology and Toxicology , 2011, DOI: 10.1186/1472-6904-11-13
Abstract: In part I of the study fourteen buprenorphine-treated and 12 methadone-treated patients were tested by cognitive tests within two months (T1), 6-9 months (T2), and 12 - 17 months (T3) from the start of opioid substitution treatment. Fourteen healthy controls were examined at similar intervals. Benzodiazepine and other psychoactive comedications were common among the patients. Test results were analyzed with repeated measures analysis of variance and planned contrasts. In part II of the study the patient sample was extended to include 36 patients at T2 and T3. Correlations between cognitive functioning and medication, substance abuse, or demographic variables were then analyzed.In part I methadone patients were inferior to healthy controls tests in all tests measuring attention, working memory, or verbal memory. Buprenorphine patients were inferior to healthy controls in the first working memory task, the Paced Auditory Serial Addition Task and verbal memory. In the second working memory task, the Letter-Number Sequencing, their performance improved between T2 and T3. In part II only group membership (buprenorphine vs. methadone) correlated significantly with attention performance and improvement in the Letter-Number Sequencing. High frequency of substance abuse in the past month was associated with poor performance in the Letter-Number Sequencing.The results underline the differences between non-randomized and randomized studies comparing cognitive performance in opioid substitution treated patients (fewer deficits in buprenorphine patients vs. no difference between buprenorphine and methadone patients, respectively). Possible reasons for this are discussed.Opioid agonists buprenorphine and methadone prevent opioid withdrawal symptoms and reduce craving for opioids [1,2]. Both drugs are used in opioid substitution treatment (OST), also known as opioid maintenance treatment. OST has proven effective in reducing illicit drug use, somatic diseases, mortality, and socia
Memory function in opioid-dependent patients treated with methadone or buprenorphine along with benzodiazepine: longitudinal change in comparison to healthy individuals
Pekka Rapeli, Carola Fabritius, Hely Kalska, Hannu Alho
Substance Abuse Treatment, Prevention, and Policy , 2009, DOI: 10.1186/1747-597x-4-6
Abstract: Within the first two months (T1) and between 6–9 months (T2) after OST admission, we followed the working memory, immediate verbal memory, and memory consolidation of 13 methadone- and 15 buprenorphine- or buprenorphine/naloxone-treated patients with BZD dependence or abuse disorder. The results were compared to those of fifteen normal comparison participants. All participants also completed a self-reported memory complaint questionnaire on both occasions.Both patient groups performed statistically significantly worse than normal comparison participants in working memory at time points T1 and T2. In immediate verbal memory, as measured by list learning at T1, patients scored lower than normal comparison participants. Both patient groups reported significantly more subjective memory problems than normal comparison participants. Patients with more memory complaints recalled fewer items at T2 from the verbal list they had learned at T1 than those patients with fewer memory complaints. The significance of the main analyses remained nearly the same when the statistical tests were performed without buprenorphine-only patients leaving 12 patients to buprenorphine/naloxone group.Working memory may be persistently affected in OST patients with BZD use. A high number of memory complaints among OST patients with BZD use may indicate memory consolidation impairment. These findings show that recovery of memory function in OD patients treated along with BZDs takes time, and their memory complaints may have practical relevance.Opioid-substitution treatment with the full mu opioid receptor agonist methadone or the partial agonist buprenorphine is the most effective treatment for OD [1,2]. Follow-up studies of OST patients have shown consistently high retention in OST, fewer crimes, reduction in substance abuse, and improved health [3,4]. However, the psychosocial recovery of OD patients during treatment is still controversial. It has been stated that while opioid abuse and other pr
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