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Search Results: 1 - 10 of 6140 matches for " Israr Ul Hassan "
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Impact of Climate Change on Epidemiology of Various Pests of Wheat Crop in Punjab Pakistan  [PDF]
Israr Arshad, Amer Rasul, Syed Ismat Hussain, Hafiz Muhammad Usman Aslam, Khizar Hayat, Malik Najam Ul Hassan, Sidra Muqeet, ? Amina, Yasir Umar, Shabab Nasir, Anum Tehseen
American Journal of Plant Sciences (AJPS) , 2019, DOI: 10.4236/ajps.2019.101018
Abstract: Wheat [Triticum aestivum L. (Poaceae)] is the staple diet of people in Pakistan. It is attacked by many types of pests. Therefore the purpose of this study was to assess the impact of climate change on the ecology and epidemiology of various wheat pests in Punjab, Pakistan. Results indicate that maximum weeds hot spots 242 (5.98%) Phalaris minor, 45 (1.18%) wild oat and 203 (5.01%) broad leaf weeds were noted in 2015. Aphid 31 (0.86%) hot spots were recorded in 2016 while maximum army worm 13 (0.26%) hot spots were noted in 2017. Maximum 70 (1.73%) spots of yellow rust and 85 (2.10%) hot spots of brown rust were observed during 2015 while 84 (4.16%) spots of loose smut were observed during 2017. ANOVA shows that years have no significant difference (P > 0.05) but weeks have significant effect on occurrence of these pest incidences except brown rust. But regression ANOVA was significant (P ≤ 0.05) and regression models equations have been developed on the bases of recorded data. Pest incidence was taken as dependent variable Y and weather factors i.e
Carbon Nanotubes in Cancer Therapy and Drug Delivery
Abdelbary M. A. Elhissi,Waqar Ahmed,Israr Ul Hassan,Vinod. R. Dhanak,Antony D'Emanuele
Journal of Drug Delivery , 2012, DOI: 10.1155/2012/837327
Abstract: Carbon nanotubes (CNTs) have been introduced recently as a novel carrier system for both small and large therapeutic molecules. CNTs can be functionalized (i.e., surface engineered) with certain functional groups in order to manipulate their physical or biological properties. In addition to the ability of CNTs to act as carriers for a wide range of therapeutic molecules, their large surface area and possibility to manipulate their surfaces and physical dimensions have been exploited for use in the photothermal destruction of cancer cells. This paper paper will discuss the therapeutic applications of CNTs with a major focus on their applications for the treatment of cancer.
Subtype Specific Differences in NS5A Domain II Reveals Involvement of Proline at Position 310 in Cyclosporine Susceptibility of Hepatitis C Virus
Israr-ul H. Ansari,Rob Striker
Viruses , 2012, DOI: 10.3390/v4123303
Abstract: Hepatitis C virus (HCV) is susceptible to cyclosporine (CsA) and other cyclophilin (CypA) inhibitors, but the genetic basis of susceptibility is controversial. Whether genetic variation in NS5A alters cell culture susceptibility of HCV to CypA inhibition is unclear. We constructed replicons containing NS5A chimeras from genotypes 1a, 2a and 4a to test how variation in carboxy terminal regions of NS5A altered the genotype 1b CsA susceptibility. All chimeric replicons including genotype 1b Con1LN-wt replicon exhibited some cell culture sensitivity to CsA with genotype 4a being most sensitive and 1a the least. The CypA binding pattern of truncated NS5A genotypes correlated with the susceptibility of these replicons to CsA. The Con1LN-wt replicon showed increased susceptibility towards CsA when proline at position 310P was mutated to either threonine or alanine. Furthermore, a 15 amino acid long peptide fused N terminally to GFP coding sequences confirmed involvement of proline at 310 in CypA binding. Our findings are consistent with CypA acting on multiple prolines outside of the previously identified CypA binding sites. These results suggest multiple specific genetic variants between genotype 1a and 1b in the C-terminus of NS5A alter the CsA susceptibility of replicons, and some variants may oppose the effects of others.
Acetylcholinesterase Based Detection of Residual Pesticides on Cotton  [PDF]
Syed Zameer Ul Hassan, Jiri Militky
American Journal of Analytical Chemistry (AJAC) , 2012, DOI: 10.4236/ajac.2012.32013
Abstract: This study describes the measurement of bio-electrical signals caused by enzymatic inhibition of acetylcholinesterase (AChE) for the detection of organophosphorous and carbamate pesticides which are the strong inhibitors of AChE and prevents its normal function of the rapid removal of acetylcholine (Ach). Biosensor Toxicity Analyzer (BTA) was used for the testing and enzyme activity was determined by acetylthiocholine chloride (ATCCl) as enzyme substrate. The monitoring of changes in bio-electrical signals caused by the interaction of biological substances and residues were evaluated. Two samples of cotton were analyzed. Cryogenic homogenization was carried out for sample pretreatment and Soxhlet extraction method (SOX) was used for extraction. The resulted extracts were concentrated and then injected in the BTA. The method shows reasonable results and can successfully be utilized for the detection of residual pesticides on different types of cotton.
Determining Irrigators Preferences for Water Allocation Criteria Using Conjoint Analysis  [PDF]
Noor Ul Hassan Zardari, Ian Cordery
Journal of Water Resource and Protection (JWARP) , 2012, DOI: 10.4236/jwarp.2012.45027
Abstract: Water allocation based on multiple criteria has the potential to maximize the total benefits to be gained from the use of a single unit of water. However most of the multi-criteria methods inherently include a considerable degree of subjectivity. In this study, we have attempted to reduce the subjectivity factor from water allocation decision-making process by introducing a conjoint analysis method. Opinions on the importance of a number of water allocation criteria were sought from a large number of irrigation farmers. The opinion survey data were then analyzed using the traditional conjoint analysis method which is widely used to analyze marketing surveys. The analysis allowed objective determination of the relative importance of five water allocation criteria (i.e. net farm income, percent of family working on the farm, amount paid to irrigation agency for canal water share). Each water allocation criteria was divided into three levels and utility values for each criteria level were estimated from the farmers’ preferences on five water allocation criteria (attributes). The conjoint survey results revealed that the respondents prefer that “annual net farm income” be the most important attribute in water allocation decisions. As would be expected the vast majority of the respondents overwhelmingly placed the “water price” in the last position.
Cyclosporine Inhibits a Direct Interaction between Cyclophilins and Hepatitis C NS5A
Fiona Fernandes,Israr-ul H. Ansari,Rob Striker
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0009815
Abstract: Hepatitis C Virus (HCV) infection is a leading indication for liver transplantation. HCV infection reoccurs almost universally post transplant, decreasing both graft longevity and patient survival. The immunosuppressant, cyclosporine A (CsA) has potent anti-HCV activity towards both HCV replicons and the genotype 2a cell culture infectious virus. Previously, we isolated mutations in the 1bN replicon with less sensitivity to CsA that mapped to both NS5A and NS5B regions of the virus. Mutations in NS5A alone conferred decreased CsA susceptibility regardless of NS5B mutations.
The Professional Medical Journal , 2008,
Abstract: Objective: To highlight etiological factors leading to radial nerve injury resulting in wrist drop, withparticular reference to iatrogenic causes. Design: Retrospection & Descriptive. Material & Methods: One hundredpatients of all ages and both sexes with wrist drop. Data of clinical assessment after detailed history and examinationas well as electro diagnostic studies was recorded on pre-designed assessment proforma. The outcome was charteddown for frequency of etiology of the wrist drop. Setting: Rehabilitation Medicine Department of Combined MilitaryHospital (CMH) Multan and Armed Forces Institute of Rehabilitation Medicine (AFIRM). Results: The major cause ofinjury was splinter/gun shot injury 31%, mis-placed injection at mid-arm 21%fracture of humerus was 21%, compressionneuropathy 16%, and stab wound 11% caused wrist drop. Electro-physiological studies revealed that 85% patients hadinjury to radial nerve at mid-arm, 9% had injury to posterior interosseous nerve while 4% had injury to superficial branchof radial nerve and only 2% had normal study. Electrodiagnostic studies also revealed that majority of the patientssuffered from axonotmesis (44%) and neurapraxia (38%), whereas (16%) were neurotmesis. Conclusion: The mostcommon cause of radial nerve injury is trauma. It is also found that the frequency of radial nerve palsy due to iatrogeniccauses is quite high. In addition to the clinical examination, the nerve conduction studies and electromyography provedto be the better investigation technique in the assessment of the location, severity and extent of the peripheral nerveinjury and subsequently guides in starting the proper treatment option due to early referral of patient to the concernedfields.
The Professional Medical Journal , 2004,
Abstract: Objective: To evaluate biochemically the water pollutionby estimating various quality parameters of ground water supply available in the southern area ofFaisalabad. Design: Prospective study Setting: Biochemistry Department Punjab Medical CollegeFaisalabad and Soil Research laboratory of AARI Jhang Road Faisalabad. Duration: May 2000 toSeptember 2000 Material & Methods: Different parameters were divided into three different categoriesi.e. Highly-desirable(HD), Maximum-permissible(MP) and In-Tolerant(IT) limit groups. Results: TotalHardness(HD) showed 35% in HD, 40% in MP and 25% in IT limits. Similarly Total Dissolved Solids(TDS) were 23% in HD, 52% in MP and 25% in IT range The Ca was 30%in HD, 50% in MP and 20%in IT limits. The Mg showed 50% in HD, 38% in MP and 12% in IT range. Similarly Cl was, 45% in HD,32% in MP and 23% in IT range. Lastly SO4 percentage showed 45% in HD, 37.5% in MP and only17.5% in IT limit. Conclusions: The result showed that people living in Bawaywala area were consuminghighly polluted water and similarly the peoples of other colonies are using more or less the same typeof water.
Relationship of Uric Acid with Superoxide Dismutase (Sod) in Induced Hyperuricemic Rat Model  [PDF]
Shiza Batool, Iftikhar Ahmed, Muhammad Sarwar, Hafeez ul Hassan
Pharmacology & Pharmacy (PP) , 2012, DOI: 10.4236/pp.2012.34054
Abstract: Increase uric acid levels have been found in oxidative stress. Urate radicals do not react with oxygen to form another peroxy radical, thus increasing the efficacy of uric acid as an antioxidant. Therefore, this study is designed to measure the level of uric acids and find out the relationship of uric acid with superoxide dismutase in induced hyperuricemic model. Forty male albino rats with an average weight of 180 ± 2 g were selected. The rats were grouped. The animals were fed on standard diet and given tap water ad libitum until treatment. Albino rats were divided into four groups. Group A(10)-control given only standard diet, group B(10) fed on 60% fructose with standard diet , group C(10) fed on fructose, standard diet and intraperitonially oxonic acid 250 mg/kg and group D (10) only on injection intraperotonially oxonic acid 250 mg/kg. At the end of study 10 mL of blood was drawn from heart of rats. Then blood was estimated for superoxide dismutase and uric acids done by kit methods randox-manual/Rx monza UA230/UA 233. Results: In Group C superoxide dismutase was found to be 32 % (244 mg/dL ± 2.23) more than control. In the same group the uric acid concentration was highly significantly correlated with control. Conclusion: The uric acid concentration increases when we take fructose up to 60% in our diet. It also increases superoxide dismutase concentration. More than this value may have inverse effect on the uric acid level and its role as an antioxidant may become inversed.
Tax Shield and Its Impact on Corporate Dividend Policy: Evidence from Pakistani Stock Market  [PDF]
Akhlaq ul Hassan, Mubashar Tanveer, Muhammad Siddique, Muhammad Mudasar
iBusiness (IB) , 2013, DOI: 10.4236/ib.2013.54023

The problem: what is the taxation impact on dividend policy? While much optimal taxation research focuses on the economic effects of taxation, the purpose of this study is to add a new dimension by investigating the relationship between taxation and payout ratio and some other variables of dividend policy. These relations are tested using the data from financial statements of KSE listed companies. The results show that tax shield has no significant relation to the dividend payout ratio but mostly dividend policy is due to the size of the firm and its profitability.

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