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Caracterización patogénica de los recién nacidos con malformaciones múltiples
Francisca Alonso Lotti,Isidro Cendán Mu?iz,María Emilia Ferrero Oteiza,Joel Roca Ortiz
Revista Cubana de Pediatr?-a , 1998,
Abstract: El Registro Cubano de Malformaciones Congénitas (RECUMAC) ha analizado 520 578 recién nacidos en 36 hospitales ginecobstétricos de 13 provincias de Cuba en un período de 12 a os (de marzo de 1985 a diciembre de 1996), en el cual la prevalencia de malformaciones congénitas al nacimiento es de 179,8 por 10 000 nacimientos. El 24,6 % de los casos presentó 2 ó más malformaciones asociadas entre sí. Se realizó la clasificación de los multimalformados y los síndromes resultaron ser los más frecuentes. Entre los cromosómicos, el síndrome de Down ocupó el primer lugar, con una prevalencia al nacimiento de 7,8 por 10 000 nacimientos. En relación con los monogénicos heredados con modelos autosómicos dominante y recesivo la acondroplasia y el albinismo presentaron el mayor número de casos para una prevalencia al nacimiento de 0,44 y 0,21 por 10 000 nacimientos, respectivamente. The Cuban Registry of Congenital Malformations (CRCM) has analyzed 520 578 newborns at 36 gynecobstetric hospitals in 13 provinces af Cuba for 12 years (from March, 1985 to December, 1996), in which the prevalence of malformations at birth is of 179.8 per 10 000 births. 24.6 % of the cases presented 2 or more malformations associated among themselves. The classification of those suffering from multimalformation was carried out and syndromes proved to be the most frequent. Within the cromosomic syndromes the Down′s syndrome was in the first place with a prevalence at birth of 7.8 per 10 000 births′. In connection with monogenic syndromes inherited with dominant and recessive autosomal models, achondroplasia and albinism had the highest number of cases for a prevalence at birth of 0.44 and 0.21 per 10 000 births, respectively.
Tendencias del síndrome de Down en Cuba: Su relación con edad materna y tasa de fecundidad
María Emilia Ferrero Oteiza,Francisca Alonso Lotti,Isidro Cendán Mu?iz,Joel Roca Ortiz
Revista Cubana de Pediatr?-a , 1998,
Abstract: Durante un período de 12 a os (1985-1996) el Registro Cubano de Malformaciones Congénitas ha analizado un total de 520 578 nacimientos procedentes de 36 hospitales ginecoobstétricos de las 14 provincias de Cuba, de los cuales 9 362 recién nacidos presentaron al menos un defecto congénito detectado antes del alta hospitalaria. De éstos, 397 recién nacidos presentaron síndrome de Down, para una prevalencia al nacimiento de 7,8 por 10 000 nacimientos en el período. Al incluir los casos diagnosticados e interrumpidos por el Programa Nacional de Diagnóstico Prenatal Citogenético (125) se estimó entonces una incidencia al nacimiento de 9,8 por 10 000 nacidos vivos. Se analizó la tendencia de la prevalencia al nacimiento del síndrome de Down en relación con la tasa de fecundidad y la edad materna. En las madres menores de 20 a os la prevalencia al nacimiento se mantuvo estable y la tasa de fecundidad decreció. En el resto de los grupos, de 20 a 34 a os y más de 35 a os decrecieron tanto la prevalencia al nacimiento como la tasa de fecundidad. En general tanto la prevalencia al nacimiento como la incidencia estimada al nacimiento tienen una tendencia decreciente, en este período. Along a 12-years period (1985-1996) the Cuban Registry of malformations has analyzed a total of 520 578 births from 36 gynecological obstetrical hospitals in all the 14 provinces of Cuba, of which 9 362 newborns presented at least one malformation found before the discharge from hospital. Of these, 397 newborns had the Down’s syndrome, for a prevalence at birth of 7,8/10 000 births in the period. When the cases diagnosed and interrupted by the National Program of Cytogenetical Prenatal Diagnosis (125) were included, then an incidence at birth of 9,8/10 000 born alive was estimated. The prevalence trend at birth of the Down’s syndrome was analyzed related to ther fertility rate and the maternal age. In mothers under 20 years of age, the prevalence at birth remained stable, and the fertility rate decreased. In the other groups, from 20 to 34 years and over 35 years of age, the prevalence at birth, as well as the fertility rate, decreased. On the whole, the prevalence at birth, as well as the estimated incidence at birth, have a decreasing trend in this period.
Comportamiento de los defectos congénitos aislados más frecuentes en Cuba
Francisca Alonso Lotti,Isidro Cendán Mu?iz,María Emilia Ferrero Oteiza,Joel Roca Ortiz
Revista Cubana de Pediatr?-a , 2000,
Abstract:
Caracterización clínica del labio leporino con fisura palatina o sin ésta en Cuba
Roca Ortiz,. Joel Luis; Cendán Mu?iz,Isidro; Alonso Lotti,Francisca; Ferrero Oteiza,María Emilia; Lantigua Cruz,Aracely;
Revista Cubana de Pediatr?-a , 1998,
Abstract: 288 newborns with cleft lips with or without cleft palate, either associated or not to other types of defects, were detected among 8 004 malformed newborns included in the cuban birth defects register from april 1985 to december 1994. this defect alone was present in 77.4 % of cases whereas cleft palate was also present in two-thirds of cases. male newborns were predominant. left-hand anatomical defect location prevailed in both sexes. as to the associated defects, chromosomal syndromes accounting for 8 % were predominant from the pathogenic view point; in addition, the prevailing syndrome was trisomy 13 which was found in 21 cases.
Caracterización clínica del labio leporino con fisura palatina o sin ésta en Cuba
. Joel Luis Roca Ortiz,Isidro Cendán Mu?iz,Francisca Alonso Lotti,María Emilia Ferrero Oteiza
Revista Cubana de Pediatr?-a , 1998,
Abstract: Entre los 8 004 recién nacidos malformados del Registro Cubano de Malformaciones Congénitas, en el período de abril de 1985 a diciembre de 1994, se detectaron 288 casos con labio leporino con fisura palatina o sin ella, aislado o asociado con otro(s) defecto(s). El defecto se presentó en su forma aislada en el 77,4 % y en más de 2/3 partes de los casos la lesión incluyó al paladar. Hubo un predominio en el sexo masculino y para la localización anatómica izquierda en uno y otro sexos. Entre los asociados, desde el punto de vista patogénico, predominaron los síndromes cromosómicos con una tasa de 8 %, y entre estos prevaleció la trisomía 13 con 21 casos. 288 newborns with cleft lips with or without cleft palate, either associated or not to other types of defects, were detected among 8 004 malformed newborns included in the Cuban Birth Defects Register from April 1985 to December 1994. This defect alone was present in 77.4 % of cases whereas cleft palate was also present in two-thirds of cases. Male newborns were predominant. Left-hand anatomical defect location prevailed in both sexes. As to the associated defects, chromosomal syndromes accounting for 8 % were predominant from the pathogenic view point; in addition, the prevailing syndrome was Trisomy 13 which was found in 21 cases.
Caracterización patogénica de los recién nacidos con malformaciones múltiples
Alonso Lotti,Francisca; Cendán Mu?iz,Isidro; Ferrero Oteiza,María Emilia; Roca Ortiz,Joel; Castillo González,Pedro; Petizco Hernández,Alida; Ferreiro,Alina;
Revista Cubana de Pediatr?-a , 1998,
Abstract: the cuban registry of congenital malformations (crcm) has analyzed 520 578 newborns at 36 gynecobstetric hospitals in 13 provinces af cuba for 12 years (from march, 1985 to december, 1996), in which the prevalence of malformations at birth is of 179.8 per 10 000 births. 24.6 % of the cases presented 2 or more malformations associated among themselves. the classification of those suffering from multimalformation was carried out and syndromes proved to be the most frequent. within the cromosomic syndromes the down′s syndrome was in the first place with a prevalence at birth of 7.8 per 10 000 births′. in connection with monogenic syndromes inherited with dominant and recessive autosomal models, achondroplasia and albinism had the highest number of cases for a prevalence at birth of 0.44 and 0.21 per 10 000 births, respectively.
Tendencias del síndrome de Down en Cuba: Su relación con edad materna y tasa de fecundidad
Ferrero Oteiza,María Emilia; Alonso Lotti,Francisca; Cendán Mu?iz,Isidro; Roca Ortiz,Joel; Pérez Valle,Andrés; Estévez Lloret,María C.;
Revista Cubana de Pediatr?-a , 1998,
Abstract: along a 12-years period (1985-1996) the cuban registry of malformations has analyzed a total of 520 578 births from 36 gynecological obstetrical hospitals in all the 14 provinces of cuba, of which 9 362 newborns presented at least one malformation found before the discharge from hospital. of these, 397 newborns had the down?s syndrome, for a prevalence at birth of 7,8/10 000 births in the period. when the cases diagnosed and interrupted by the national program of cytogenetical prenatal diagnosis (125) were included, then an incidence at birth of 9,8/10 000 born alive was estimated. the prevalence trend at birth of the down?s syndrome was analyzed related to ther fertility rate and the maternal age. in mothers under 20 years of age, the prevalence at birth remained stable, and the fertility rate decreased. in the other groups, from 20 to 34 years and over 35 years of age, the prevalence at birth, as well as the fertility rate, decreased. on the whole, the prevalence at birth, as well as the estimated incidence at birth, have a decreasing trend in this period.
A DDS-Based Scalable and Reconfigurable Framework for Cyber-Physical Systems
Ismael Etxeberria-Agiriano,Isidro Calvo,Liliana Montero,Ivan Alonso
International Journal of Software Engineering & Applications , 2012,
Abstract: Cyber-Physical Systems (CPSs) involve the interconnection of heterogeneous computing devices which areclosely integrated with the physical processes under control. Often, these systems are resource-constrainedand require specific features such as the ability to adapt in a timeliness and efficient fashion to dynamicenvironments. Also, they must support fault tolerance and avoid single points of failure. This paperdescribes a scalable framework for CPSs based on the OMG DDS standard. The proposed solution allowsreconfiguring this kind of systems at run-time and managing efficiently their resources.
A DDS-Based Scalable and Reconfigurable Framework for Cyber-Physical Systems
Ismael Etxeberria-Agiriano,Isidro Calvo,Liliana Montero,Ivan Alonso
Computer Science , 2012, DOI: 10.5121/ijsea.2012.3403
Abstract: Cyber-Physical Systems (CPSs) involve the interconnection of heterogeneous computing devices which are closely integrated with the physical processes under control. Often, these systems are resource-constrained and require specific features such as the ability to adapt in a timeliness and efficient fashion to dynamic environments. Also, they must support fault tolerance and avoid single points of failure. This paper describes a scalable framework for CPSs based on the OMG DDS standard. The proposed solution allows reconfiguring this kind of systems at run-time and managing efficiently their resources.
Relación entre ocupación materna y cuatro tipos de malformaciones congénitas
. Marta Arrechaderra álvarez,Eddy Infante Pozo,Francisca Alonso Lotti,Elio Antonio Prieto González
Revista Cubana de Investigaciones Biom??dicas , 1999,
Abstract:
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