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Search Results: 1 - 10 of 2437 matches for " Irina Georgieva "
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New Records of Microcystins in Some Bulgarian Water Bodies of Health and Conservational Importance  [PDF]
Vera Pavlova, Maya Stoyneva, Vesela Georgieva, Desislav Donchev, Lisa Spoof, Jussi Meriluoto, Zlatka Bratanova, Irina Karadjova
Journal of Water Resource and Protection (JWARP) , 2014, DOI: 10.4236/jwarp.2014.65044
Abstract:

Microcystins cause acute hepatotoxicity and chronic liver tumor promotion. This study presents the results of HPLC DAD analyses and their LC-MS confirmation of samples from five Bulgarian water bodies (reservoirs Stoudena, Pchelina, Bistritsa and lakes Dourankoulak, Vaya). The total concentration of microcystins in water samples ranged from 0.1 to 26.5 μg/l. The amount of microcystins in the biomasses ranged from 11.4 to 49.6 μg/g (d.w.). The high percent of positive samples in which the most toxic microcystin-LR is recorded, can serve as a strong alarm for the necessity of a serious study and relevant discussion of the problem with responsible authorities at national level.

Evaluation of behavioral changes and subjective distress after exposure to coercive inpatient interventions
Irina Georgieva, Cornelis L Mulder, Richard Whittington
BMC Psychiatry , 2012, DOI: 10.1186/1471-244x-12-54
Abstract: Effectiveness was assessed through ratings of patient behavior immediately after exposure to a coercive measure and 24 h later. Subjective distress was examined using the Coercion Experience Scale at debriefing. Regression analyses were performed to compare these outcome variables across the four types of coercive interventions.Using univariate statistics, no significant differences in effectiveness and subjective distress were found between the groups, except that patients who were involuntarily medicated experienced significant less isolation during the measure than patients who underwent combined measures. However, when controlling for the effect of demographic and clinical characteristics, significant differences on subjective distress between the groups emerged: involuntary medication was experienced as the least distressing overall and least humiliating, caused less physical adverse effects and less sense of isolation. Combined coercive interventions, regardless of the type, caused significantly more physical adverse effects and feelings of isolation than individual interventions.In the absence of information on individual patient preferences, involuntary medication may be more justified than seclusion and mechanical restraint as a coercive intervention. Use of multiple interventions requires significant justification given their association with significant distress.Coercive interventions such as seclusion, involuntary medication and mechanical restraint are common methods for managing violent behavior during psychiatric hospitalization. Even though they are intended to protect patients and those around them, they are highly controversial, because they restrict freedom and are used against a patient’s will. They are even more problematic when used in combination – for example, when seclusion is combined with mechanical restraint. They can also be extremely traumatic [1], causing physical and psychological damage to patient and staff alike [2]. As a result, pr
The rich get richer and the poor get poorer
Ingmar H. A. Franken,Irina Georgieva,Peter Muris,Ap Dijksterhuis
Judgment and Decision Making , 2006,
Abstract: Some studies have found that choices become more risk averse after gains and more risk seeking after losses, although other studies have found the opposite. The latter tend to use hypothetical cases that encourage deliberation. In the current study, we examined the effects of prior gains and losses on a task designed to encourage less reflective decision making, the Iowa Gambling Task (IGT). Fifty participants conducted a manipulated decision-making task in which one group gained money, whereas the other group lost money, followed by the IGT. Participants who experienced a prior monetary loss displayed more risky choice behavior on the IGT than subjects who experienced a prior gain. These effects were not mediated by a positive or negative affect, although the sample size may have been too small to detect a small effect.
Warehousing and OLAP Analysis of Bibliographic Data  [PDF]
Tsvetanka Georgieva-Trifonova
Intelligent Information Management (IIM) , 2011, DOI: 10.4236/iim.2011.35023
Abstract: In this paper, the system bgMath/OLAP for warehousing and online analytical processing bibliographic data is proposed. The implemented system can be useful for the users maintaining their electronic libraries with publications in order to monitoring, evaluating and comparing the scientific development of particular researchers, entire research groups, certain scientific fields and problems.
Association study in the 5q31-32 linkage region for schizophrenia using pooled DNA genotyping
Irina Zaharieva, Lyudmila Georgieva, Ivan Nikolov, George Kirov, Michael J Owen, Michael C O'Donovan, Draga Toncheva
BMC Psychiatry , 2008, DOI: 10.1186/1471-244x-8-11
Abstract: We saturated the interval between markers D5S666 and D5S436 with 90 polymorphic microsatellite markers and genotyped two sets of DNA pools consisting of 300 SZ patients of Bulgarian origin and their 600 parents. Positive associations were followed-up with SNP genotyping.Nominally significant evidence for association (p < 0.05) was found for seven markers (D5S0023i, IL9, RH60252, 5Q3133_33, D5S2017, D5S1481, D5S0711i) which were then individually genotyped in the trios. The predicted associations were confirmed for two of the markers: D5S2017, localised in the SPRY4-FGF1 locus (p = 0.004) and IL9, localized within the IL9 gene (p = 0.014). Fine mapping was performed using single nucleotide polymorphisms (SNPs) around D5S2017 and IL9. In each region four SNPs were chosen and individually genotyped in our full sample of 615 SZ trios. Two SNPs showed significant evidence for association: rs7715300 (p = 0.001) and rs6897690 (p = 0.032). Rs7715300 is localised between the TGFBI and SMAD5 genes and rs6897690 is within the SPRY4 gene.Our screening of 5q31-32 implicates three potential candidate genes for SZ: SMAD5, TGFBI and SPRY4.Schizophrenia (SZ) is a common, severe and disabling disorder that in most cases requires a long-term medical and social care. The lifetime risk for SZ in the population worldwide is around 1%. Family, adoption and twin studies have shown conclusively that a genetic component plays the most important role in its aetiology [1]. At present, the number of susceptibility loci, the disease risk conferred by each locus and the degree of interaction between them remain unknown [2]. The mode of transmission is complex and non-Mendelian and is probably contributed by a small number of genes of moderate effect, or by many genes of small effect, or a mixture of the two [3].In the present study we investigated one strong region of linkage to schizophrenia: 5q31-32. This region emerged as one of the five most consistent regions in a meta-analysis of the genome
The Economies of the BELL Countries (Bulgaria, Estonia, Latvia and Lithuania) after Their EU Accession
Emilia Georgieva
Review of European Studies , 2012, DOI: 10.5539/res.v4n5p191
Abstract: The acronym BELL stands for the 4 EU member countries from Central and Eastern Europe (Bulgaria, Estonia, Latvia and Lithuania) which are well known for their fiscal stability and low indebtedness. Being a representative of one of them (Bulgaria) the author of this article aims to follow the dynamics of their economic development after their accession to the EU. The special points of reference used are the compulsory convergence criteria each country wishing to join the Eurozone has to meet. Particular attention has been paid to the role of the exchange rate regime and the impact of the world economic crisis on the cycle model and the “corridor” marking the fluctuations of each of the interpreted macroeconomic indicators. The BELL’s economic development has been opposed to that of the PIIGS countries, albeit only in terms of budget deficit (-) or surplus (+) and consolidated general debt as a percentage of GDP. The author has examined the role the European funds and programmes play for the economies of the BELL countries, some major benefits of their EU membership for their citizens and businesses, as well as the specific characteristics of the social activity aimed to overcome the effects of the crisis. A variety of research methods have been used in the process, such as the scientific abstraction method (analysis, synthesis, induction and deduction), historic and systemic and logical methods, empirical and comparative analysis.
The role of EU institutions in implementing its monetary policy
Emilia GEORGIEVA
Eastern Journal of European Studies , 2011,
Abstract: The main goal of the current article is to illustrate in detail the powers of the EU institutions to implement its monetary policy. The methods used to explore the topic and to draw the conclusions and interpret the findings are based on deduction and induction. On the grounds of the information presented in the article the following conclusions have been drawn: the relations between the EU institutions responsible for implementing its monetary policy (the European Central Bank, the European Parliament, the Council, the European Commission and others) are entirely based on fundamental principles laid down for all its institutions; the commitments of the institutions implementing the EU monetary policy are strictly stipulated in its primary legislation and are mostly related to the establishment of the EU Economic and Monetary Union, the framing, planning and implementing of the common monetary policy, the management of the Monetary Union. In the conditions of world financial and economic crisis the EU has attempted to respond adequately to its monetary policy problems, commensurate with the scope and matching the specific nature of this crisis.
DEVIANT BEHAVIOR IN ADOLESCENTS WITH MILD INTELLECTUAL DISABILITY
Emilija GEORGIEVA
Journal of Special Education and Rehabilitation , 2012,
Abstract:
Why the Sunspot Cycle Is Double Peaked
K. Georgieva
ISRN Astronomy and Astrophysics , 2011, DOI: 10.5402/2011/437838
Abstract: Many sunspot cycles are double peaked. In 1967, Gnevyshev suggested that actually all cycles have two peaks generated by different physical mechanisms, but sometimes the gap between them is too short for the maxima to be distinguished in indices of the total sunspot activity. Here, we show that indeed all cycles have two peaks easily identified in sunspot activity in different latitudinal bands. We study the double peaks in the last 12 sunspot cycles and show that they are manifestation of the two surges of toroidal field—the one generated from the poloidal field advected all the way on the surface to the poles, down to the tachocline and equatorward to sunspot latitudes, and another one generated from the poloidal field diffused at mid-latitudes from the surface to the tachocline and transformed there into toroidal field. The existence of these two surges of toroidal field is due to the relative magnitudes of the speed of the large-scale solar meridional circulation and the diffusivity in the solar convection zone which are estimated from geomagnetic data. 1. Introduction By the term “solar activity,” usually any type of variation in the appearance or energy output of the Sun, is understood. Elements of solar activity are sunspots, solar flares, coronal mass ejections, coronal holes, total and spectral solar irradiance, and so forth. The most prominent evidence of solar activity and with the longest data record, though not geoeffective themselves but related to geoeffective active regions, are sunspots. Very big sunspots can be seen with naked eye, and old chronicles testify that they have been indeed observed even in ancient times. There is evidence that the Greeks knew of them at least by the 4th century BC, and the earliest records of sunspots observed by Chinese astronomers are from 28?BC. However, systematic observations of sunspots began only early in the 17th century after the telescope was invented. As many other great discoveries, the sunspot cycle was discovered by chance. Heinrich Schwabe, a German pharmacist and amateur astronomer, was convinced that there must be a planet, tentatively called Vulcan, inside the orbit of Mercury. Because of the close proximity to the Sun, it would have been very difficult to observe Vulcan, and Schwabe believed one possibility to detect the planet might be to see it as a dark spot when passing in front of the Sun. For 17 years, from 1826 to 1843, on every clear day, Schwabe would scan the Sun and record its spots trying to detect Vulcan among them. He did not find the planet but noticed the regular variation
Why the sunspot cycle is double peaked
Katya Georgieva
Physics , 2011,
Abstract: Many sunspot cycles are double peaked. In 1967 Gnevyshev suggested that actually all cycles have two peaks generated by different physical mechanisms, but sometimes the gap between them is too short for the maxima to be distinguished in indices of the total sunspot activity. Here we show that indeed all cycles have two peaks easily identified in sunspot activity in different latitudinal bands. We study the double peaks in the last 12 sunspot cycles and show that they are manifestation of the two surges of toroidal field - the one generated from the poloidal field advected all the way on the surface to the poles, down to the tachocline and equatorward to sunspot latitudes, and another one generated from the poloidal field diffused at midlatitudes from the surface to the tachocline and transformed there into toroidal field. The existence of these two surges of toroidal field is due to the relative magnitudes of the speed of the large-scale solar meridional circulation and the diffusivity in the solar convection zone which are estimated from geomagnetic data.
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