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Search Results: 1 - 10 of 3243 matches for " Irene; Artajona-Rosino "
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Current management of gastric cancer
Viúdez-Berral,Antonio; Miranda-Murua,Coro; Arias-de-la-Vega,Fernando; Hernández-García,Irene; Artajona-Rosino,Alicia; Díaz-de-Lia?o,álvaro; Vera-García,Ruth;
Revista Espa?ola de Enfermedades Digestivas , 2012, DOI: 10.4321/S1130-01082012000300006
Abstract: gastric cancer is a disease with high incidence and mortality in our population. the prognosis of patients with this disease is closely related to the neoplasm stage at diagnosis, including the following characteristics of the tumor: extension into the gastric wall thickness, spread to locoregional lymph nodes and the ability to generate distant metastases, as described by the tnm classification. for localized tumors characterized only by invasion of mucosa or submucosa at diagnosis, survival at 5 years is between 70 and 95% with exclusive surgical management; however, when extension into the gastric wall is higher and/or there is locoregional nodal involvement, survival decreases to 20-30% at 5 years. currently, at high-volume centers, the extent of gastrectomy is individualized based on several parameters, which in an increasing number of cases allows a total gastrectomy with d2 lymphadenectomy and preservation of the spleen and pancreas. this improved procedure increases the chance of r0 surgery and improves the relationship between resected and affected lymph nodes, resulting in a decreased risk of the long-term locoregional recurrence. to improve these results, different therapeutic strategies combining chemotherapy or chemoradiotherapy with surgery have been tested. previously, the intergroup 0116 clinical trial, published in 2001, which changed clinical practice in the united states, showed that adjuvant chemoradiotherapy improved survival (from 26 to 37 months overall survival) of these patients. in europe, perioperative chemotherapy has been considered the standard treatment, since the publication of two randomized phase iii trials showed an increase at 5 years survival in the group treated with chemotherapy.
The role that oilseeds, including new hi-oleic varieties can play in improving the profile of fat intake by the UK population  [PDF]
Janice Irene Harland
Agricultural Sciences (AS) , 2014, DOI: 10.4236/as.2014.53024
Abstract:


The production in the EU of the oilseeds, rapeseed and sunflower, has increased dramatically over the last 20 years. Much of the oil produced after crushing is used for culinary purposes; this enhanced intake of vegetable oil has led to a substantial change of fatty acid (FA) supply. This has been conclusively demonstrated by taking the UK oil supply data and by use of the FA profile of the key oils converting the supply data into a FA profile of the UK market place for 2008-2012. The most marked changes are a reduction in saturated fat (SFA) and an increase in monounsaturated fatty acids (MUFA) available for consumption. Furthermore the introduction of varieties of hi-oleic sunflower oil can further affect the market FA profile. The fat profiles of rapeseed and sunflower oils are considered healthy and they can have a positive impact when included in the diet, particularly as a replacement for oils or fats rich in SFA. In the UK and much of Europe, adult SFA intake continues to exceed recommendations. While reductions in the UK population’s SFA intake have occurred over the last 20 years, these are modest and it may be timely to identify ways in which SFA intake can be further reduced. To do this, the UK market FA supply data has been analysed alongside the profile of FA intake from adults recording their intake in national dietary surveys in order to identify if the market supply affects overall FA consumption. There is an indication that market oil supply is reflected in adults dietary intake of the main groups of FA. Consequently changes made to the oil profile of oilseeds by plant breeders and use of the resulting healthier oils by food manufacturers could have important roles to play in helping adults to achieve the recommended intake of SFA and also improve the overall fat quality in their diet leading to enhanced long-term health and well-being. Thus changes made in pri

The Relationship between Access to Mass Media and HIV/AIDS Related Knowledge, Beliefs and Behaviours in Kenya  [PDF]
Irene Muli, Stephen Lawoko
Psychology (PSYCH) , 2014, DOI: 10.4236/psych.2014.57084
Abstract:

Aim: We scrutinized the association between access to mass media and HIV/AIDS related knowledge, beliefs and behaviours in Kenya. Methods: Data on a representative sample of Kenyan women between 15 - 30 years of age (n = 3909) was retrieved from the Kenyan demographic and health survey (DHS 2008) and analyzed using Chi-square tests and binary logistic regression. Results: Media use was common with over 70% of participants using radio at least once a week. Between 3% - 30% of participants had poor to inadequate knowledge/beliefs about HIV/AIDS, with variations depending on demographic and social factors such as age, education, literacy, wealth and residential area. HIV/AIDS knowledge, beliefs and behaviours were associated with exposure to media, even after control for possible co-variation with social and demographic factor. Conclusion: Despite wide exposure to media among young Kenyan women, substantial proportions have poor to inadequate knowledge of the aetiology, risk/protective factors and control measures of HIV/AIDS. Yet, such knowledge was positively associated with media use. Media thus could ideally be used to implement a comprehensive awareness campaign in the general population about the aetiology, risk/protective factors and control measures in HIV/AIDS.

Síntesis hidrogeológica y modelización regional de la Cuenca Media del Tajo asistida por un SIG
Heredia, J.,Martín-Loeches, M.,Rosino, J.,del Olmo, C.
Estudios Geologicos , 2001, DOI: 10.3989/egeol.01571-2125
Abstract: This work resumes the results obtained from the application of a numerical code for hydrogeologic modelization (NCHM) assisted through a Geographic information System (GIS) to an area of 20,952 km2 of the middle part of the Tajo basin; it includes both the tertiary basins of Campo Ara uelo and Madrid and the igneous-metamorphic massif until a depth of 5,500 m. The cities of Madrid, Toledo and Talavera de la Reina are located in the selected area and the Jerte fault and the confluence area of the rivers Tajo and Tietar constitute its westemmost part. The objectives of this work are for one side to study the problem related with the integration of several hidrogeologic formations of differentiated characteristics in one single model and for the other, to push forward in the regional knowledge from an integrated and multidisciplinary perspective. One isotropic and five anisotripic models were performed. In the anisotropic ones, the influence in the flow of the water of 3 different sets of fractures -N 105, N 142.5 y N 168.75- and a regional esquistosity of N 140, was considered. The calibration of the models rests upon both restored piezometric levels and the base yield of the hydrographic network. Different values of the calibrated parameters were obtained according to each model. The quality of the adjustments is acceptable; each one of the models shows a better adjustment respect the others in those areas where the features that are represented fix with those in the real system. The evolution of the permeability with the depth fix with the expected one, being kx/kz = ky/kz = 1, for the first 200 m and 0.1 for the rest. A calibrated recharge of 3 % of the precipitation was obtained for the tertiary, 2 % in the Guadarrama-Gredos system and 0.5 % in Montes de Toledo range. Information from different sources, either doctoral thesis or studies from ENRESA CEDEX, CHT and DGOH and the SIGMA project was integrated and contrasted to perform the model. The chosen confiuration ARC/INFO-IDRISIVISUAL MODFLOW has shown its usefulness and versatility to face the modelization of this area, which is characterized for its complexity and big extension. En el presente trabajo se exponen los resultados obtenidos de la aplicación de un Código Numérico de Modelización Hidrogeológica (CNMH) asistido por un Sistema de Información Geográfica (SIG) a un área de 20.952 km2 de la cuenca media del Tajo que incluye tanto a las depresiones terciarias del Campo Ara uelo y de Madrid, parcialmente, como al sustrato Igneo-metamórfico del macizo Ibérico hasta una profundidad de 5.500 m. Geo
The Use of “Scalp Block” in Pediatric Patients  [PDF]
Joseph Sebeo, Irene P. Osborn
Open Journal of Anesthesiology (OJAnes) , 2012, DOI: 10.4236/ojanes.2012.23017
Abstract: Infiltration of the nerves of the scalp with local anesthetics is used in adults for a variety of head and neck procedures and craniotomies with many benefits, from hemodynamic stability to reduced postoperative pain. We here succinctly review the current evidence for “scalp block” in pediatric patients.
A Liquid Chromatography Assay for the Simultaneous Quantification of Piperacillin and Ciprofloxacin in Human Plasma and Dialysate in Critically Ill Patients Undergoing Continuous Renal Replacement Therapy  [PDF]
Florian Scheer, Irene Kr?mer
International Journal of Analytical Mass Spectrometry and Chromatography (IJAMSC) , 2014, DOI: 10.4236/ijamsc.2014.22005
Abstract:

Piperacillin/tazobactam and ciprofloxacin are often used in combination as initial empiric anti-biotic therapy in critical ill patients. Especially in patients undergoing continuous renal replacement therapy (CRRT) the pharmacokinetics of antimicrobial agents can be highly variable. In order to avoid under- or overdosage of antibiotics therapeutic drug monitoring (TDM) is highly re-commendable. Based on two known HPLC assays for piperacillin a new method in combination with solid phase extraction (SPE) for the simultaneous determination of piperacillin and ciprofloxacin was developed. Method validation was performed according to the EMA guideline on validation of bioanalytical methods. The HPLC column used was a Perfect Bond ODS-HD C18 analytical column (100 mm × 4.6 mm i.d., particle size 5 μm), equipped with a guard column (10 mm × 4.6 mm, particle size 5 μm) containing the same packing material. Detection wavelength was set at 228 nm for piperacillin and benzylpenicillin was used as internal standard (IS). Ciprofloxacin was determined at two wavelengths (280 nm, 315 nm). This newly developed HPLC method in combination with SPE-extraction allows an accurate, precise, specific and efficient determination of piperacillin and ciprofloxacin in biological matrices. Results allow the calculation of all relevant pharmacokinetic data for critically ill patients undergoing CRRT and the optimization of dosing and TDM.

Determinants of Loan Defaults in Some Selected Credit Unions in Kumasi Metropolis of Ghana  [PDF]
Edward Yeboah, Irene Mirekuah Oduro
Open Journal of Business and Management (OJBM) , 2018, DOI: 10.4236/ojbm.2018.63059
Abstract:
Credit Unions play a pivotal role in the Microfinance Industry in Ghana. They are not only deeply rooted in financial intermediation but also provide favorable terms and conditions in financial products and services to their members compared to banks and other financial institutions. The sustainability of Credit Unions has been threatened by the incidence of loan defaults or non-performing loans. The diagnostics of the causes of loan defaults in Credit Unions become paramount toward sound credit risk management practices. The study relied on primary data. Purposive sampling technique was applied to select 244 Credit Union members. Questionnaires were used for data collection and logistic regression model was adopted. The study utilized Statistical Product and Service Solution (SPSS v. 20) and Stata (v.14) as statistical tools for data analysis. The results reveal that education, loan diversion, monitoring, marital status and income are significant factors that influence loan default. Thus, credit education should be intensified and that effective loan monitoring should be vigorously pursued. Additionally, loan appraisal systems should be robust with the application and development of credit scoring systems that will factor in key variables of loan default.
Análise retrospectiva do implante de prótese peniana em diabéticos
Naliato, Erika C.O.;Ellinger, Vivian;Baccarini Neto, Rosino;Meirelles, Ricardo M.R.;Zagury, Le?o;
Arquivos Brasileiros de Endocrinologia & Metabologia , 1999, DOI: 10.1590/S0004-27301999000300005
Abstract: eleven diabetic patients from the instituto estadual de diabetes e endocrinologia luiz capriglione who received a penile prostheses implant for erectile dysfunction were analyzed with the purpose of evaluating pre-implant conditions and safety of the procedure. surgical indication was based in the incomplete or negative response to erection test or unwillingness to use other methods for treatment of the dysfunction. all patients were satisfied with the results of the surgery and only one presented with post-surgery complication, resulting from mechanical failure of the prosthesis. we conclude that the penile prosthesis implant can be considered a safe method of treatment, especially in low social-economical classes of the diabetic population, because it eliminates the need for long pharmacological treatments and there are few complications in the surgical follow-up.
Multimodal cycles with linear map having exactly one fixed point
Irene Mulvey
International Journal of Mathematics and Mathematical Sciences , 2001, DOI: 10.1155/s0161171201003969
Abstract: We describe a class of cycles that cannot be forced by a cycle whose linear map has exactly one fixed point.
On the structure of the totally ordered set of unimodal cycles
Irene Mulvey
International Journal of Mathematics and Mathematical Sciences , 2001, DOI: 10.1155/s0161171201003350
Abstract: We continue the study of a class of unimodal cycles where each cycle in the class is forced by every unimodal cycle not in the class. For every order, we identify the cycle in the class of that order, which is maximal with respect to the forcing relation.
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