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Search Results: 1 - 10 of 220632 matches for " Ion C. Baianu "
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Categorial Ontology of Complex Systems, Meta-Systems and Levels: The Emergence of Life, Human Consciousness and Society
Ion C. Baianu,James F. Glazebrook
Brain. Broad Research in Artificial Intelligence and Neuroscience , 2010,
Abstract: Relational structures of organisms and the human mind are naturally represented in terms of novel variable topology concepts, non-Abelian categories and Higher Dimensional Algebra{ relatively new concepts that would be defined in this tutorial paper. A unifying theme of local-to-global approaches to organismic development, evolution and human consciousness leads to novel patterns of relations that emerge in super- and ultra- complex systems in terms of compositions of local procedures [1]. The claim is defended in this paper that human consciousness is unique and should be viewed as an ultra-complex, global process of processes, at a meta-level not sub{summed by, but compatible with, human brain dynamics [2]-[5]. The emergence of consciousness and its existence are considered to be dependent upon an extremely complex structural and functional unit with an asymmetric network topology and connectivities{the human brain. However, the appearance of human consciousness is shown to be critically dependent upon societal co-evolution, elaborate language-symbolic communication and `virtual', higher dimensional, non{commutative processes involving separate space and time perceptions. Theories of the mind are approached from the theory of levels and ultra-complexity viewpoints that throw new light on previous semantic models in cognitive science. Anticipatory systems and complex causality at the top levels of reality are discussed in the context of psychology, sociology and ecology. A paradigm shift towards non-commutative, or more generally, non-Abelian theories of highly complex dynamics [6] is suggested to unfold now in physics, mathematics, life and cognitive sciences, thus leading to the realizations of higher dimensional algebras in neurosciences and psychology, as well as in human genomics, bioinformatics and interactomics. The presence of strange attractors in modern society dynamics gives rise to very serious concerns for the future of mankind and the continued persistence of a multi-stable Biosphere.
Algebraic Topology Foundations of Supersymmetry and Symmetry Breaking in Quantum Field Theory and Quantum Gravity: A Review
Ion C. Baianu,James F. Glazebrook,Ronald Brown
Symmetry, Integrability and Geometry : Methods and Applications , 2009,
Abstract: A novel algebraic topology approach to supersymmetry (SUSY) and symmetry breaking in quantum field and quantum gravity theories is presented with a view to developing a wide range of physical applications. These include: controlled nuclear fusion and other nuclear reaction studies in quantum chromodynamics, nonlinear physics at high energy densities, dynamic Jahn-Teller effects, superfluidity, high temperature superconductors, multiple scattering by molecular systems, molecular or atomic paracrystal structures, nanomaterials, ferromagnetism in glassy materials, spin glasses, quantum phase transitions and supergravity. This approach requires a unified conceptual framework that utilizes extended symmetries and quantum groupoid, algebroid and functorial representations of non-Abelian higher dimensional structures pertinent to quantized spacetime topology and state space geometry of quantum operator algebras. Fourier transforms, generalized Fourier-Stieltjes transforms, and duality relations link, respectively, the quantum groups and quantum groupoids with their dual algebraic structures; quantum double constructions are also discussed in this context in relation to quasi-triangular, quasi-Hopf algebras, bialgebroids, Grassmann-Hopf algebras and higher dimensional algebra. On the one hand, this quantum algebraic approach is known to provide solutions to the quantum Yang-Baxter equation. On the other hand, our novel approach to extended quantum symmetries and their associated representations is shown to be relevant to locally covariant general relativity theories that are consistent with either nonlocal quantum field theories or local bosonic (spin) models with the extended quantum symmetry of entangled, 'string-net condensed' (ground) states.
Algebraic Topology Foundations of Supersymmetry and Symmetry Breaking in Quantum Field Theory and Quantum Gravity: A Review
Ion C. Baianu,James F. Glazebrook,Ronald Brown
Physics , 2009, DOI: 10.3842/SIGMA.2009.051
Abstract: A novel algebraic topology approach to supersymmetry (SUSY) and symmetry breaking in quantum field and quantum gravity theories is presented with a view to developing a wide range of physical applications. These include: controlled nuclear fusion and other nuclear reaction studies in quantum chromodynamics, nonlinear physics at high energy densities, dynamic Jahn-Teller effects, superfluidity, high temperature superconductors, multiple scattering by molecular systems, molecular or atomic paracrystal structures, nanomaterials, ferromagnetism in glassy materials, spin glasses, quantum phase transitions and supergravity. This approach requires a unified conceptual framework that utilizes extended symmetries and quantum groupoid, algebroid and functorial representations of non-Abelian higher dimensional structures pertinent to quantized spacetime topology and state space geometry of quantum operator algebras. Fourier transforms, generalized Fourier-Stieltjes transforms, and duality relations link, respectively, the quantum groups and quantum groupoids with their dual algebraic structures; quantum double constructions are also discussed in this context in relation to quasi-triangular, quasi-Hopf algebras, bialgebroids, Grassmann-Hopf algebras and higher dimensional algebra. On the one hand, this quantum algebraic approach is known to provide solutions to the quantum Yang-Baxter equation. On the other hand, our novel approach to extended quantum symmetries and their associated representations is shown to be relevant to locally covariant general relativity theories that are consistent with either nonlocal quantum field theories or local bosonic (spin) models with the extended quantum symmetry of entangled, 'string-net condensed' (ground) states.
Complex Systems Analysis of Cell Cycling Models in Carcinogenesis
I. C. Baianu
Quantitative Biology , 2004,
Abstract: Carcinogenesis is a complex process that involves dynamically inter-connected modular sub-networks that evolve under the influence of micro-environmentally induced perturbations, in non-random, pseudo-Markov chain processes. An appropriate n-stage model of carcinogenesis involves therefore n-valued Logic treatments of nonlinear dynamic transformations of complex functional genomes and cell interactomes. Lukasiewicz Algebraic Logic models of genetic networks and signaling pathways in cells are formulated in terms of nonlinear dynamic systems with n-state components that allow for the generalization of previous, Boolean or "fuzzy", logic models of genetic activities in vivo. Such models are then applied to cell transformations during carcinogenesis based on very extensive genomic transcription and translation data from the CGAP databases supported by NCI. Such models are represented in a Lukasiewicz-Topos with an n-valued Lukasiewicz Algebraic Logics subobject classifier description that represents non-random and nonlinear network activities as well as their transformations in carcinogeness. Specific models for different types of cancer are then derived from representations of the dynamic state-space of LT non-random, pseudo-Markov chain process, network models in terms of cDNA and proteomic, high throughput analyses by ultra-sensitive techniques. This novel theoretical analysis is based on extensive CGAP genomic data for human tumors, as well as recently published studies of cyclin signaling. Several such specific models suggest novel clinical trials and rational therapies of cancer through re-establishment of cell cycling inhibition in stage III cancers.
Cell Cycling Models of Carcinogenesis: A Complex Systems Analysis
V. I. Prisecaru,I. C. Baianu
Quantitative Biology , 2004,
Abstract: A new approach to the modular, complex systems analysis of nonlinear dynamics in cell cycling network transformations involved in carcinogenesis is proposed. Carcinogenesis is a complex process that involves dynamically inter-connected biomolecules in the intercellular, membrane, cytosolic, nuclear and nucleolar compartments that form numerous inter-related pathways. One such family of pathways contains the cell cyclins. Cyclins are proteins that link several critical pro-apoptotic and other cell cycling/division components, including the tumor suppressor gene TP53 and its product, the Thomsen-Friedenreich antigen (T antigen), Rb, mdm2, c-Myc, p21, p27, Bax, Bad and Bcl-2, which all play major roles in neoplastic transformation of many tissues. This novel theoretical analysis based on recently published studies of cyclin signaling, with special emphasis placed on the roles of cyclins D1 and E, suggests novel clinical trials and rational therapies of cancer through reestablishment of cell cycling inhibition in metastatic cancer cells.
Applications of Novel Techniques to Health Foods, Medical and Agricultural Biotechnology
I. C. Baianu,P. R. Lozano,V. I. Prisecaru,H. C. Lin
Quantitative Biology , 2004,
Abstract: Selected applications of novel techniques in Agricultural Biotechnology, Health Food formulations and Medical Biotechnology are being reviewed with the aim of unraveling future developments and policy changes that are likely to open new niches for Biotechnology and prevent the shrinking or closing the existing ones. Amongst the selected novel techniques with applications to both Agricultural and Medical Biotechnology are: immobilized bacterial cells and enzymes, microencapsulation and liposome production, genetic manipulation of microorganisms, development of novel vaccines from plants, epigenomics of mammalian cells and organisms, as well as biocomputational tools for molecular modeling related to disease and Bioinformatics. Both fundamental and applied aspects of the emerging new techniques are being discussed in relation to their anticipated impact on future biotechnology applications together with policy changes that are needed for continued success in both Agricultural and Medical Biotechnology. Several novel techniques are illustrated in an attempt to convey the most representative and powerful tools that are currently being developed for both immediate and long term applications in Agriculture, Health Food formulation and production, pharmaceuticals and Medicine. The research aspects are naturally emphasized in our review as they are key to further developments in Medical and Agricultural Biotechnology.
Single Cancer Cell Detection by Near Infrared Microspectroscopy, Infrared Chemical Imaging and Fluorescence Microspectroscopy
I. C. Baianu,D. Costescu,N. E. Hofmann,S. S. Korban
Quantitative Biology , 2004,
Abstract: Novel techniques are currently being developed and established for the accurate chemical analysis and detection of single cancer cells, single embryos and single seeds by Fourier Transform Near Infrared (FT-NIR) Microspectroscopy, Fourier Transform Infrared (FT-IR), Fluorescence and High-Resolution NMR (HR-NMR). The first FT-NIR chemical images of biological systems approaching 1micron resolution are here reported. 400 and 500 MHz, H-1 NMR analyses were carried out that allowed the selection of mutagenized embryos. Detailed chemical analyses are being demonstrated to be also possible by FT-NIR Chemical Imaging/ Microspectroscopy of single cancer cells. FT-NIR Microspectroscopy and Chemical Imaging are also shown to be potentially important in Functional Genomics and Proteomics research through the rapid and accurate detection of high-content microarrays (HCMA). Multi-photon (MP), pulsed femtosecond laser NIR Fluorescence Excitation techniques were shown to be capable of Single Molecule Detection (SMD. Thus, MP NIR excitation for Fluorescence Correlation Spectroscopy (FCS) allowed not only single molecule detection, but also molecular dynamics observations and high resolution, submicron imaging of sub-femtoliter volumes inside living cells with 0.25 micron spatial resolution, in both normal and cancer cells, as well as neoplastic tissues. These novel, ultra-sensitive and rapid FT-NIR/FCS analyses have, therefore, substantial potential for numerous applications in important research areas, such as: medicine, medical/cancer research, pharmacology, agricultural biotechnology, food safety, as well as clinical diagnosis of viral diseases and cancers.
ION ALEXANDRU C RLAN, The Forms without a Content, a Romanian Brand reviews and reading notes
ION ALEXANDRU C?RLAN
Revista Roman? de Sociologie , 2008,
Abstract: Starting from a recent volume issued by the Romanian researcher Constantin Schifirne , the author tries to prove the inadequacy of the term brand to the Romanian culture and civilization as it belongs to the so-called notion of the "forms without a content" deviced by the Romanian critic titu Maiorescu in the 19 th century already.
Forecast the Impact of Bucharest – Bra ov Highway on the Economic and Functional Structure of Human Settlements in Ilfov County
C?T?LINA C?RSTEA,FLORENTINA ION,PETRONELA NOV?CESCU
Romanian Review of Regional Studies , 2011,
Abstract: One of the most publicized issues concerning the infrastructure of Romania is the Bucharest-Bra ov highway. The long-awaited project aims to streamline the traffic between the Capital and the central part of the country, representing the central area of the Pan - European Road Corridor IV. The length of the highway on the territory of Ilfov County is 31 km, representing 17% of the total length of Bucharest- Bra ov highway. The start of the highway will have strong effects on economic structure and on the way the Bucharest Metropolitan Area will work. We can expect an increase in the disparities between the settlements of Ilfov County. This pattern is also observable on the Bucharest-Ploie ti corridor where, in recent years, much of the Ilfov county's economic activities have migrated to the north, especially along that corridor. Besides economic migration, intense residential migration followed the Bucharest – Ploie ti corridor, residents of the Bucharest itself moving out to the north of Ilfov County. Probably, the future Bucharest – Bra ov highway will lead to an increased suburbanization and periurbanization, this in turn giving way to the crowding of the area by businesses eager to have access to the highway. This project will likely increase the gap between north and south of Ilfov County. In addition to changes that may occur at the county level, changes will also have an impact on the localities themselves since the areas located near the highway will have an economic and demographic growth rate superior to more remote areas. In this sense, we conducted a comparative analysis between eight settlements of Ilfov county crossed by the Bucharest-Bra ov highway in order to assess the impact. This analysis was based on the information obtained from site and statistical indicators that were processed to obtain a clear picture of the situation in the examined territory.
Non Security – Premise of Cybercrime
Ion IVAN,Daniel MILODIN,C?t?lin SBORA
Theoretical and Applied Economics , 2012,
Abstract: It is presented the concept of cyber crime. There are detailed the vulnerabilities of IT applications. There are listed the types of Internet fraud. There are analyzed the predisposing factors of cyber crime. There are identified the deficiencies of the security systems. It is build a model for information security management.
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