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Search Results: 1 - 10 of 7668 matches for " Inho Park "
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Willingness to Pay for the Subscription Fee of Public Broadcasting System  [PDF]
Inho Park, Hyun Soon Park
Advances in Journalism and Communication (AJC) , 2014, DOI: 10.4236/ajc.2014.21001
Abstract: The study aims at developing communication strategies for the public broadcasting system according to WTP (Willingness to Pay) for the subscription fee and the audience’s perception of the public broadcasting system as a public good. A quasi-experiment was conducted for audiences who have previously watched public broadcasting channels. According to the results, those respondents who think of public broadcasting as a public good and who think that public broadcasting performs its public role well have high intention to pay the subscription fee. Respondents feel at a loss when they pay the subscription fee, and the willingness to pay the fee goes down.
Study design and methods of the Ansan Geriatric Study (AGE study)
Changsu Han, Sangmee Jo, Nan Kim, Inho Jo, Moon Park
BMC Neurology , 2009, DOI: 10.1186/1471-2377-9-10
Abstract: The AGE study was designed as a population-based prospective cohort study on health, aging, and common geriatric diseases of elderly Koreans aged 60 to 84 years. The inception cohort was recruited in May 2002. The first-wave and second-wave studies were performed using uniform and structured procedures. At the screening study, 2,767 participants were enrolled. Participants (1391 in the first wave study and 841 in the second wave study) were recruited and completed the evaluation. The prevalence of geriatric disease and related factors in elderly Koreans were estimated.Here, we report the design and sampling participants, measurement tools, and characteristics of the AGE study. This cohort study will allow a detailed study of the longitudinal comprehensive data on health information of elderly Koreans, thereby contributing to policy formulation and planning of health, welfare management, and other social services in Korea.More than one-quarter of the world's population will be over the age of 60 by the year 2010 [1]. As in most other countries, the proportion of elderly people in Korea is increasing every year due to decreased birth rates and increased longevity. The proportion of those 65 years and older in Korea was approximately 8.3% in 2003 and is expected to rise to 15% in 2019 [2]. As Korea will have the highest proportion of elderly people in the world by 2050, public health concerns about geriatric diseases in Korea have taken on greater importance. There are increasing demands for national policies and programs to deal with problems affecting the elderly. Thus, there is a need for research focusing on age-related conditions that contribute significantly to chronic illness and disability in elderly Koreans.Although there have been several Western elderly cohort studies such as the Baltimore Longitudinal Study on Aging in the USA [3], the Framingham study in the USA [4], the Rotterdam elderly study in the Netherlands [5], and the Canadian Study on Health and A
No difference in stroke knowledge between Korean adherents to traditional and western medicine – the AGE study: an epidemiological study
Moon Ho Park, Sangmee Jo, Inho Jo, Eunkyung Kim, Su-Yong Eun, Changsu Han, Min Kyu Park
BMC Public Health , 2006, DOI: 10.1186/1471-2458-6-153
Abstract: A total of 2,767 subjects selected randomly from the Ansan Geriatric Study in South Korea were questioned about stroke. Their answers were compared with their sociodemographic data and other variables.Only 44.8% of participants correctly identified stroke as a vascular disease in the human brain. Sudden numbness or weakness was the most frequently identified stroke warning sign (60.2%). Hypertension (66.7%) and mental stress (62.2%) were most frequently identified as stroke risk factors. The contributions of diabetes mellitus and cardiovascular disease to stroke were underestimated; they were identified as risk factors by 28.3% and 18.6% of participants, respectively. The predictors for poor knowledge of stroke warning signs and risk factors were similar irrespective of preference for Western or Oriental medical treatment, and included those with lower levels of education and inaccurate definition of stroke. Television and radio (40.3%) were the most frequent sources of stroke information for both groups.This study shows that knowledge of stroke is similar among Koreans with preferences for either Western or Oriental medical treatment and that misunderstandings about stroke are common among the Korean elderly. In order to prevent and manage stroke effectively, public health education regarding basic concepts of stroke is necessary. This should target those with a lower level of education and a misunderstanding of the definition of stroke.Stroke is the leading cause of death among Koreans [1,2]. Control of stroke risk factors and, when stroke occurs, early initiation of treatment, represent primary steps in stroke prevention and reduction of mortality, sequelae and length of hospitalization [3,4]. However, inadequate or incorrect knowledge about stroke among the general public may hinder prevention and delay the initiation of appropriate treatment. Thus, it is important to increase public awareness of stroke signs and symptoms and potential stroke risk factors [5,6].
Morbidity and related factors among elderly people in South Korea: results from the Ansan Geriatric (AGE) cohort study
Eun-kyung Woo, Changsu Han, Sangmee Jo, Min Park, Sungsoo Kim, Eunkyung Kim, Moon Park, Juyoung Lee, Inho Jo
BMC Public Health , 2007, DOI: 10.1186/1471-2458-7-10
Abstract: A total of 2,767 subjects (1,215 men and 1,552 women) aged 60–84 years were randomly selected from September 2002 to August 2003 in Ansan, South Korea. Data on sociodemographic and health characteristics, and clinical diagnosis were collected using questionnaires. When available, the medical records and medications taken by the subjects were also cross-checked.Of the total subjects, 78.0% reported diagnosed disease, 11.0% had been cured, and 46.8% had been diagnosed with more than two diseases. The mean number of morbidities per person among elderly Koreans was 1.62 ± 1.35 (mean ± standard deviation), and women had a greater number of diseases per person than did men. The most common morbidities were chronic diseases such as hypertension, arthritis, and diabetes mellitus. In women, osteoporosis and arthritis were the second and third most prevalent diseases, respectively. Morbidity was significantly associated with gender, employment, household income, alcohol intake, self-assessed health status, and worries about health.These data will enhance understanding of the patterns of health problems among elderly Koreans and will contribute to the application of appropriate intervention strategies.The increasingly ageing populations in developed countries have recently become the focus of substantial research interest. In 2000, those aged 65 and older constituted from 6.0 to 15.5% of the populations in Asia, Europe, and North America. These figures are expected to increase to approximately 12 to 24.3% by 2030 [1]. As health status has a substantial influence on the quality of life in elderly populations, many countries have been making tremendous efforts to improve the understanding of the health status of this age group. Both perceived health and chronic illness are major elements of health status in the elderly, because perceived health declines with age and chronic health problems increase with age. Furthermore, there is a growing body of evidence indicating that older
An optimal relative isoperimetric inequality in concave cylindrical domains in
Kim Inho
Journal of Inequalities and Applications , 2000,
Abstract: We prove an optimal relative isoperimetric inequality in concave cylindrical domains in , which generalizes the well-known two-dimensional relative isoperimetric inequality in a planar sector with angle greater than or equal to .
Expressed Sequence Tags for Bovine Muscle Satellite Cells, Myotube Formed-Cells and Adipocyte-Like Cells
Eun Ju Lee, Majid Rasool Kamli, Smritee Pokharel, Adeel Malik, K. M. A. Tareq, Abdul Roouf Bhat, Hee-Bok Park, Yong Seok Lee, SangHoon Kim, Bohsuk Yang, Ki Young Chung, Inho Choi
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0079780
Abstract: Background Muscle satellite cells (MSCs) represent a devoted stem cell population that is responsible for postnatal muscle growth and skeletal muscle regeneration. An important characteristic of MSCs is that they encompass multi potential mesenchymal stem cell activity and are able to differentiate into myocytes and adipocytes. To achieve a global view of the genes differentially expressed in MSCs, myotube formed-cells (MFCs) and adipocyte-like cells (ALCs), we performed large-scale EST sequencing of normalized cDNA libraries developed from bovine MSCs. Results A total of 24,192 clones were assembled into 3,333 clusters, 5,517 singletons and 3,842contigs. Functional annotation of these unigenes revealed that a large portion of the differentially expressed genes are involved in cellular and signaling processes. Database for Annotation, Visualization and Integrated Discovery (DAVID) functional analysis of three subsets of highly expressed gene lists (MSC233, MFC258, and ALC248) highlighted some common and unique biological processes among MSC, MFC and ALC. Additionally, genes that may be specific to MSC, MFC and ALC are reported here, and the role of dimethylarginine dimethylaminohydrolase2 (DDAH2) during myogenesis and hemoglobin subunit alpha2 (HBA2) during transdifferentiation in C2C12 were assayed as a case study. DDAH2 was up-regulated during myognesis and knockdown of DDAH2 by siRNA significantly decreased myogenin (MYOG) expression corresponding with the slight change in cell morphology. In contrast, HBA2 was up-regulated during ALC formation and resulted in decreased intracellular lipid accumulation and CD36 mRNA expression upon knockdown assay. Conclusion In this study, a large number of EST sequences were generated from the MSC, MFC and ALC. Overall, the collection of ESTs generated in this study provides a starting point for the identification of novel genes involved in MFC and ALC formation, which in turn offers a fundamental resource to enable better understanding of the mechanism of muscle differentiation and transdifferentiation.
Salivary levels of cortisol and chromogranin A in patients with burning mouth syndrome: A case-control study  [PDF]
Chieko Shigeyama-Haruna, Inho Soh, Akihiro Yoshida, Shuji Awano, Hisashi Anan, Toshihiro Ansai
Open Journal of Stomatology (OJST) , 2013, DOI: 10.4236/ojst.2013.31008
Abstract: Burning mouth syndrome (BMS) is a poorly understood oral pain disorder characterized by a painful burning sensation in the oral cavity without any mucosal abnormalities. In this study, we evaluated the salivary cortisol and chromogranin A (CgA) levels of patients with BMS in comparison with age-matched controls. Subjects (n = 114) included 81 BMS patients and 33 controls. Patients with BMS were further classified into a subgroup of subjects who occasionally feel a burning sensation (BMS 1), and a subgroup of subjects who always feel a burning sensation (BMS 2). Salivary cortisol and CgA levels were measured using ELISA kits. All individuals with BMS had significantly higher cortisol and CgA levels than the controls did. Furthermore, when comparing the controls with each BMS subgroup, salivary levels of cortisol were significantly higher in both subgroups than controls. In contrast, the level of CgA was significantly higher in the BMS 2 subgroup only. Multiple regression analysis revealed a significant independent association between salivary levels of cortisol and BMS even after adjustment for gender, antidepressant or antianxiety drug use and hypertension (drug-treated). The study revealed that a significant association was observed between salivary cortisol levels and BMS.
Problems and Future Approaches for Assessment of Periodontal Disease
Toshihiro Ansai,Shuji Awano,Inho Soh
Frontiers in Public Health , 2014, DOI: 10.3389/fpubh.2014.00054
Abstract:
Human AQP5 Plays a Role in the Progression of Chronic Myelogenous Leukemia (CML)
Young Kwang Chae, Sung Koo Kang, Myoung Sook Kim, Janghee Woo, Juna Lee, Steven Chang, Dong-Wook Kim, Myungshin Kim, Seonyang Park, Inho Kim, Bhumsuk Keam, Jiyoung Rhee, Nam Hee Koo, Gyeongsin Park, Soo-Hyun Kim, Se-Eun Jang, Il-Young Kweon, David Sidransky, Chulso Moon
PLOS ONE , 2008, DOI: 10.1371/journal.pone.0002594
Abstract: Aquaporins (AQPs) have previously been associated with increased expression in solid tumors. However, its expression in hematologic malignancies including CML has not been described yet. Here, we report the expression of AQP5 in CML cells by RT-PCR and immunohistochemistry. While normal bone marrow biopsy samples (n = 5) showed no expression of AQP5, 32% of CML patient samples (n = 41) demonstrated AQP5 expression. In addition, AQP5 expression level increased with the emergence of imatinib mesylate resistance in paired samples (p = 0.047). We have found that the overexpression of AQP5 in K562 cells resulted in increased cell proliferation. In addition, small interfering RNA (siRNA) targeting AQP5 reduced the cell proliferation rate in both K562 and LAMA84 CML cells. Moreover, by immunoblotting and flow cytometry, we show that phosphorylation of BCR-ABL1 is increased in AQP5-overexpressing CML cells and decreased in AQP5 siRNA-treated CML cells. Interestingly, caspase9 activity increased in AQP5 siRNA-treated cells. Finally, FISH showed no evidence of AQP5 gene amplification in CML from bone marrow. In summary, we report for the first time that AQP5 is overexpressed in CML cells and plays a role in promoting cell proliferation and inhibiting apoptosis. Furthermore, our findings may provide the basis for a novel CML therapy targeting AQP5.
Opposing Regulation of PROX1 by Interleukin-3 Receptor and NOTCH Directs Differential Host Cell Fate Reprogramming by Kaposi Sarcoma Herpes Virus
Jaehyuk Yoo equal contributor,Ha Neul Lee equal contributor,Inho Choi,Dongwon Choi,Hee Kyoung Chung,Kyu Eui Kim,Sunju Lee,Berenice Aguilar,Jinjoo Kang,Eunkyung Park,Yong Suk Lee,Yong-Sun Maeng,Nam Yoon Kim,Chester J. Koh,Young-Kwon Hong
PLOS Pathogens , 2012, DOI: 10.1371/journal.ppat.1002770
Abstract: Lymphatic endothelial cells (LECs) are differentiated from blood vascular endothelial cells (BECs) during embryogenesis and this physiological cell fate specification is controlled by PROX1, the master regulator for lymphatic development. When Kaposi sarcoma herpes virus (KSHV) infects host cells, it activates the otherwise silenced embryonic endothelial differentiation program and reprograms their cell fates. Interestingly, previous studies demonstrated that KSHV drives BECs to acquire a partial lymphatic phenotype by upregulating PROX1 (forward reprogramming), but stimulates LECs to regain some BEC-signature genes by downregulating PROX1 (reverse reprogramming). Despite the significance of this KSHV-induced bidirectional cell fate reprogramming in KS pathogenesis, its underlying molecular mechanism remains undefined. Here, we report that IL3 receptor alpha (IL3Rα) and NOTCH play integral roles in the host cell type-specific regulation of PROX1 by KSHV. In BECs, KSHV upregulates IL3Rα and phosphorylates STAT5, which binds and activates the PROX1 promoter. In LECs, however, PROX1 was rather downregulated by KSHV-induced NOTCH signal via HEY1, which binds and represses the PROX1 promoter. Moreover, PROX1 was found to be required to maintain HEY1 expression in LECs, establishing a reciprocal regulation between PROX1 and HEY1. Upon co-activation of IL3Rα and NOTCH, PROX1 was upregulated in BECs, but downregulated in LECs. Together, our study provides the molecular mechanism underlying the cell type-specific endothelial fate reprogramming by KSHV.
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