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Search Results: 1 - 10 of 30109 matches for " Ildefonso; Santos-Preciado "
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Nuevo esquema de vacunación en México
Santos-Preciado José Ignacio
Salud Pública de México , 1999,
Enfrentando el bioterrorismo: aspectos epidemiológicos, clínicos y preventivos de la viruela
Franco-Paredes,Carlos; Río,Carlos del; Nava-Frías,Margarita; Rangel-Frausto,Sigfrido; Téllez,Ildefonso; Santos-Preciado,José Ignacio;
Salud Pública de México , 2003, DOI: 10.1590/S0036-36342003000400009
Abstract: the worldwide eradication of smallpox, a major achievement in public health, is currently threatened by the risk of bioterrorism. the debate on the destruction of the variola virus in the two reference laboratories of the world health organization has dramatically switched to the preservation of the remaining virus after the september 2001 terrorist events in the u.s. along with the intentional release of bacillus anthracis in the u.s. the risk of intentional release of variola virus constitutes a minimal, yet possible risk. a smallpox epidemic could have a devastating impact due to its elevated morbidity and mortality that would inflict in non-immune human population, in addition to the ensuing panic and social unrest. therefore, the development of national preparedness and response plans along with the availability of smallpox vaccine to be used in the post-exposure phase represent a fundamental part of the preventive efforts to cope with bioterrorism. reestablishing a preventive vaccination program was recently recommended by the advisory committee on immunization practices (acip). however, the vaccine currently available has historically been associated with serious adverse reactions, even death. thus, this recommendation has not been universally accepted. to counter an epidemic of smallpox, medical personnel in the frontline need to be prepared with updated smallpox infor mation to identify, diagnose, isolate, and treat cases if a bioterrorist attack should occur. herein we present an in-depth review for health care personnel with relevant epidemiologic, clinical, and preventive information on smallpox.
Freedom, Justice, and Neglected Tropical Diseases
Carlos Franco-Paredes ,Jose I. Santos-Preciado
PLOS Neglected Tropical Diseases , 2011, DOI: 10.1371/journal.pntd.0001235
Mortalidad en menores de cinco a?os mexicanos en 2004: hacia los objetivos del milenio
Lozano-Ascencio, Rafael;Santos-Preciado, José Ignacio;
Boletín médico del Hospital Infantil de México , 2005,
Abstract: introduction. for mexico, to achieve the millennium development goals and particularly goal number 4, relative to fewer than 5 mortality, has multiple implications. in order to reduce under 5 mortality from 46 to 15.2 per 1 000 live births mortality, multiple public health actions have to be undertaken in a coordinated fashion by all of the institutions that conform the national health system. materials and methods. estimates by the national population council (conapo) were analyzed. the data base of registered deaths compiled by the national institute for geography and health statistics and the ministry of health between 1990-2002 and for 2004 were also reviewed and analyzed. results. according to conapo estimates, in 1990 under 5 mortality in mexico city (federal district) was 28.4 per 1 000 live births, while in the state of chiapas the rate was 65; that is 2.3 times higher risk of dying in this region of the country. in 2004 the figures for these 2 federal entities had dropped significantly to 14.4 and 26.3 respectively, lowering the difference in risk to 1.8 for the latter, yet still leaving chiapas in greater risk. at present, the primary causes of under 5 mortality include perinatal causes, congenital malformations, lesions and accidents. although infectious diseases as a cause of death have been significantly reduced, at a national level, they still appear in the top causes of mortality in children under 5. conclusion. mexico is among the few countries in the correct or adequate path for reducing under 5 mortality. nevertheless, there are still significant obstacles that need to be resolved and challenges to be addressed. the compression of the infant mortality and the gap among states is undoubtedly one of the most important issues to be addressed in the immediate future.
Commentary: improving the health of neglected populations in Latin America
Carlos Franco-Paredes, Danielle Jones, Alfonso J Rodríguez-Morales, José Santos-Preciado
BMC Public Health , 2007, DOI: 10.1186/1471-2458-7-11
Abstract: It is frequently implied in the global health literature that underdevelopment among human populations implies suffering. Indeed, living in the most resource-constrained settings with the worst possible health undeniably ensues human suffering. Thus, the life journey of the more than one billion people living in extreme poverty may occasionally provide them with some food, some maternal milk, dirty water; and often no opportunities for education and jobs; and consequently, a lack of health [1,2].The current world order for people living in these conditions places them far away from the ethical and moral premise of the Universal Declaration of Human Rights and in a sharp evolutionary disadvantage [3,4]. In the case of Latin America, many millions of people die every year as a direct consequence of a vicious cycle of poverty, disease, and underdevelopment. In their struggle for survival, these individuals spend most of their existence gasping for breaths of humanity in the streets of major cities, rural areas, or shantytowns. The tragic reality is that the moral distance between the developed world and the forgotten populations in Latin America, may seem farther than the many million miles between the earth and the next planet. This distance can erode our moral identity enough to make the existence of the most vulnerable populations invisible: these people are "the nobodies".Microbes have profoundly influenced the dynamics of human societies throughout the history of humankind by playing a key role as agents of natural selection [2,4]. Tragically, in this evolutionary struggle for survival, microbes have consistently abused the most impoverished human populations who dwell in unsanitary and crowded resource-constrained settings (Figure 1). This is why infectious diseases (most of which are preventable by simple cost-effective interventions) continue to impose an incalculable source of human misery and ever-rising death tolls. More than 95% of deaths due to infectious
Perspectiva histórica de la viruela en México: aparición, eliminación y riesgo de reaparición por bioterrorismo
Franco-Paredes, Carlos;Lammoglia, Lorena;Santos-Preciado, José Ignacio;
Gaceta médica de México , 2004,
Abstract: smallpox has been considered a disease of historical interest. however, given the 2001 terrorist events in the u.s. with intentional release of spores of bacillus anthracis; and the current political worldwide agenda, the risk of bioterrorism has become a global public health concern. the risk of an intentional release of variola virus as a biological weapon mandates a critical review of the historical impact of the disease in our country and the possible risk of its intentional reemergence. smallpox was introduced into susceptible indian populations in the americas in the 16th century, contributing to the collapse of the aztec empire. francisco xavier balmis start a vaccination campaign in the new world, and his efforts are considered the first eradication campaign of vaccine preventable diseases. due to his efforts, smallpox was eliminated in mexico in 1951. in the posteradication era, there is small but finite risk of intentional release of variola virus. in response to this risk, mexico has developed a comprehensive national preparedness plan. the impact of a new epidemic of smallpox will be considered a catastrophic event from both a historical and public health perspectives.
The global burden of neglected tropical diseases
Herrera, Jessica S.;Franco-Paredes, Carlos;Santos-Preciado, José Ignacio;
Boletín médico del Hospital Infantil de México , 2011,
Abstract: the neglected tropical diseases (ntds) consist of a group of chronic, debilitating, and poverty-promoting parasitic, bacterial, and viral and fungal infections that are widespread among people in poor rural or peri-urban communities living in tropical or subtropical areas. however, due to population mobility, diseases such as chagas disease can be diagnosed anywhere on the globe. the ntds are disabling, disfiguring and deadly diseases impacting more than one billion people worldwide. they also impair physical and cognitive development, cause adverse pregnancy outcomes, and limit adult productivity in the workforce. the global burden of disease associated with the ntds is comparable to other infectious diseases such as that of malaria or tuberculosis. controlling or eliminating ntds represents an affordable opportunity to improve the health of poor communities, which may ultimately promote social development.
Agentes del bioterrorismo: preparándose para lo impensable
Franco-Paredes, Carlos;Rodríguez-Morales, Alfonso;Santos-Preciado, José Ignacio;
Revista de investigación clínica , 2005,
Abstract: the september 11, 2001 terrorist attacks in the usa demonstrated our vulnerability to terrorist raids. furthermore, in the same year inhalational anthrax cases in humans caused by the international release of bacillus anthracis spores via the usa postal system inflicted a lot of panic and terror over the civilian population. the succeeding terrorist events scattered in several other countries are continous reminders of our failness and of the risk that terrorists attempts in the future may be implemented by means of deliberate evil release of biological agents. these events may be perpetrated by either the release of an infectious agent or any of its products in order to spread death or sickness in humans, animals, or plants with the obnoxius purpose of scaring governments and societies for the profit of particular ideological causes. in the current article, we present a review of the main bioterrorism agents, as well as a historical and clinical aspects and their significance for public health preparedness and response.
Inmunizaciones y equidad en el Plan Regional del Sistema Mesoamericano de Salud Pública
Franco-Paredes,Carlos; Hernández-Ramos,Isabel; Santos-Preciado,José Ignacio; ,;
Salud Pública de México , 2011, DOI: 10.1590/S0036-36342011000900006
Abstract: national immunization rates indicate high vaccine coverage in mesoamerica, but there is growing evidence that the most vulnerable groups are not being reached by immunization programs. therefore, there is likely low effective vaccine coverage in the region, leading to persistent and growing health inequity. the planning phase of this project was from june to december 2009. the project will be conducted in the target populations which includes children under five, pregnant women, and women of child-bearing age from the most vulnerable populations within countries of the mesoamerican region, as indicated geographically by a low human development index (hdi) and/or high prevalence of poverty at the municipal level and through the use of participatory methods to define poverty and vulnerability in local contexts. we defined three lines of action for vaccine-preventable disease interventions: 1) pilot projects to fill gaps in knowledge; 2) strengthening immunization policy; and 3) implementation of evidence-based practices. health system strengthening through health equity is the central regional objective of the immunization workgroup. we hope to have a transformational impact on health systems so as to improve effective coverage, including vaccine and other integrated primary healthcare services.
Aspectos clínicos y epidemiológicos de la influenza
Carlos Franco-Paredes,Alfonso J. Rodríguez-Morales,José I. Santos-Preciado
CIMEL. Ciencia e Investigación Médica Estudiantil Latinoamericana , 2006,
Abstract: La influenza es una infección contagiosa de origen viral considerada una de las causas más importantes de infecciones de las vías respiratorias. Los síntomas son parecidos a los del catarro común o resfriado, sin embargo, son más severos y su inicio es generalmente abrupto. La influenza puede afectar a un importante número de personas de todos los grupos etáreos durante la aparición de epidemias. La enfermedad frecuentemente requiere de atención médica y hospitalización, contribuyendo sustancialmente a pérdidas económicas, exceso en el número de hospitalizaciones y muertes. La capacidad del virus de la influenza A y B de sufrir cambios antigénicos graduales en sus dos antígenos de superficie, la hemoaglutinina y la neuraminidasa complica la vacunación contra esta enfermedad. Las epidemias de influenza han sido responsables de un promedio de 36 000 muertes por a o en países como EE UU durante la década de los noventas, afectando a todos los grupos etáreos, pero principalmente en ni os menores de 2 a os y en adultos mayores de 65 a os. En el presente artículo se revisan los aspectos más importantes relacionados con la etiología, epidemiología, manifestaciones clínicas, complicaciones, diagnóstico, prevención y tratamiento de las infecciones producida por los virus de influenza
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