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Search Results: 1 - 10 of 133 matches for " Ifeoma Nneka Nweke "
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Glucose lowering effect of leaf extracts of Viscum Album in normal
Emenike Jacob Nwaegerue,Ifeoma Nneka Nweke,Christian Chinyere Ezeala,Prince C Unekwe
Journal of Research in Medical Sciences , 2007,
Abstract: BACKGROUND: The use of plants in the treatment of diabetes mellitus is a well-established practice in traditional medicine. Viscum album has been recommended for the treatment of several diseases. This study evaluated the glucose lowering effect of leaf extracts of this plant in normal and streptozotocin induced diabetic rats. METHODS: Leaf extracts of Viscum album were prepared with 80 % ethanol and administered to normal and diabetic New Zealand white rats. The LD50 was determined by the Karbar method. The glucose lowering effect was assessed in these animals in comparison to normal saline and glibenclamide. Blood glucose was estimated with the aid of a glucose sensor. RESULTS: The LD50 was 1520 mg/kg. A dose dependent lowering effect of the fasting blood glucose was observed in both the normal and diabetic rats, with maximum lowering occurring 6 hours after extract administration. The patterns of effect were similar to that produced by glibenclamide. CONCLUSIONS: Leaf extracts of Viscum album showed a significant glucose lowering effect in normal and diabetic rats. Extracts from this plant could therefore, be useful in controlling blood glucose level. KEY WORDS: Animal models, diabetes mellitus, Viscum album, hypoglycemic effect, streptozotocin.
Platelet Activity in Patients with Type 2 Diabetes in Eastern Nigeria
Nweke Ifeoma Nneka,Mbah Anthony Uchenna,Ezeala Christian Chinyere,Ewesiobi Austine Ikechukwu,Okechi Obioma Onyemaechi,Eroegbusi Joseph Nwobi
Research Journal of Pharmacology , 2013, DOI: 10.3923/rjpharm.2012.48.51
Abstract: Platelet dysfunction is one of the major mechanisms underpinning cardiovascular diseases in diabetes mellitus. The researchers hypothesize that a significant proportion of Nigerian diabetic patients have altered platelet activation and adhesiveness which could predispose to thrombotic disorders. To evaluate platelet adhesiveness in type 2 diabetic Nigerians as a measure of platelet dysfunction. A total 50 patients (30 males and 20 females) aged 30-70 years with established diagnosis of type 2 diabetes on their first visit to diabetes clinic of Abia State University Teaching Hospital, Aba in Eastern Nigeria and 30 apparently healthy age-matched controls (15 males and 15 females) were recruited into this study. Blood samples were collected from the diabetic patients and controls after an overnight fast for determination of platelet counts and platelet adhesiveness and results compared. The mean platelet count of the patients, 234 +/- 77x109 L-1 was not significantly different from that of the controls, 238 +/- 77x109 L-1 (p>0.05). The mean platelet adhesiveness of the patients 65.2 +/- 15.6% was however significantly higher than the mean value of the controls, 44.1 +/- 8.8% (p<0.05). There was a positive linear correlation between the fasting plasma glucose levels and platelet adhesiveness indices.
A Rare Classical Presentation of Bardet-Biedl Syndrome in a Three-Year-Old Male from South East Nigeria: A Case Report  [PDF]
Nneka C. Okoronkwo
Case Reports in Clinical Medicine (CRCM) , 2016, DOI: 10.4236/crcm.2016.58044
Abstract: Bardet-Biedl Syndrome (BBS) is a rare autosomal recessive ciliopathy characterized by obesity, post-axial polydactyly, renal abnormalities, mental retardation, pigmentary retinopathy and hypogenitalism. Diagnosis is rare in early childhood, and only few of the features are present at that age. This is because the disease is slow evolving. However, it is possible to find majority of the component of this syndrome in very young children. A 3-year old very obese male presented with clinical features of sepsis and congestive cardiac failure. He is a product of non-consanguineous marriage with unremarkable family history. Both parents are of the Ibo tribe in Nigeria. Polydactyly was noticed at birth. There was delay in some aspects of his developmental milestone. Examination revealed mild hypertelorism and retrognathia, polydactyly of both feet with syndactyly of the big and second toes. Other findings were short broad hands, mottled pigments on the retina, moderate mental retardation, hypogenitalism, nephrotic syndrome, renal tubulopathy, hyperglycaemia and hypopigmented skin lesions. A case of BBS with all the primary features and some secondary manifestations in a very young child is hereby reported. A high index of suspicion for BBS should be shown in any young child with at least one of the features of this syndrome. This will enhance earlier diagnosis and improve disease outcome.
Cultural Dependency: A Philosophical Insight  [PDF]
Bonachristus Umeogu, Ojiakor Ifeoma
Open Journal of Philosophy (OJPP) , 2012, DOI: 10.4236/ojpp.2012.22019
Abstract: Every independent country always celebrates or mark the day they were free from colonial rule in the form of “independence day celebrations”. The impression was that they were no longer slaves working under a colonial master. A fleeting glance at cultural markets reveals that despite other competing countries like India, China and Mexico, American culture dominates. This dependency on American products for arts, entertainment, dressing, and lifestyle changes in general is the major thrust of this paper. When a people’s way of life is dictated by the life of another, is it not a form of colonialism? The electronic colonialism theory was used to explain that this dominance by one culture is the modern form of colonialism and has far reaching catastrophic consequences for the dependents and needs to be checked to avoid disaster.
Constructionist Theory of Representation in Language and Communication: A Philosophical Analysis  [PDF]
Bonachristus Umeogu, Ojiakor Ifeoma
Open Journal of Philosophy (OJPP) , 2012, DOI: 10.4236/ojpp.2012.22021
Abstract: There is nothing as an innocent word because every word no matter how simple it sounds is loaded with meaning. For communication to have taken place, the meaning of a word or symbol is grasped and understood by the receiver. This paper maintains that there are variables which influence the construction and decoding of meaning with the resultant effect that no two individuals construct meanings in uniform way.
Gender Domination in Nigerian Public Relations  [PDF]
Bonachristus Umeogu, Ojiakor Ifeoma
Advances in Applied Sociology (AASoci) , 2012, DOI: 10.4236/aasoci.2012.22020
Abstract: Does gender influence practice? This paper using the theory of agenda setting and constructionist theory of representation assesses the public relations profession in relation to the value, treatment and power accorded to the different gender in the course of their professional duties. It was found out that even though there are fewer men in number, the males have more power than their female counterparts. Also, gender, directly or indirectly influence treatment and value. This paper is highly significant in the face of the global call for equal playing ground for both male and female in all spheres of life.
Crisis Journalism and World Peace  [PDF]
Bonachristus Umeogu, Ojiakor Ifeoma
Advances in Applied Sociology (AASoci) , 2012, DOI: 10.4236/aasoci.2012.22021
Abstract: With the increase in violence and unrest in many countries, the searchlight has been turned on the media who are supposed to work for peace. This paper is of the position that journalism has a big role to play in maintaining relative peace just as they have the power to fuel crisis. In as much as objectivity should be upheld, it has to go with responsibility.
Sycophancy and Objective Journalism  [PDF]
Bonachristus Umeogu, Ojiakor Ifeoma
Advances in Applied Sociology (AASoci) , 2012, DOI: 10.4236/aasoci.2012.23022
Abstract: Objective journalism is the desire and aim of every society and media house. However, such noble aspiration is beclouded and usurped by sycophancy and sycophantic reporting. This development denies the public the right to true information and invariably leads to loss of reputation by the media house. This paper looks at sycophancy in the Nigerian media by looking at the reasons for its unbridled spread, effects on the public, media houses, individuals and the government of the day.
The Prevalence of Haemoparasitic Infection in Dogs Attending ECWA Vertinary Clinic, Bukuru, Jos South Local Government Area, Plateau State  [PDF]
Nonyelu Maureen Ifeoma
Advances in Microbiology (AiM) , 2013, DOI: 10.4236/aim.2013.33043

This study was conducted to investigate the prevalence of haemoparasites of dogs attending ECWA veterinary Clinic, Bukuru, Jos south local government area in Plateau state, Nigeria, and to determine the effective control strategy. From July to September 2011, blood samples of 150 dogs were collected and examined under light microscope. The age, sex and breed of the dogs were also recorded. Wet and unstained blood film shows no motility hence no motile haemoparasite while the Giemsa stained blood smear techniques of both thick and thin film, showed the presence of only Babesia spp in 89 (59.3%), while 61 (40.7%) were negative for any haemoparasite.

Prevalence and Socio-Demographic Determinants of Depression in Women: A Comparison between Pre-Menopausal and Post-Menopausal Attendees of the General Outpatient Department in Fmc Lokoja  [PDF]
Obianma Nneka Onya, Chinenye Otorkpa
Open Journal of Depression (OJD) , 2018, DOI: 10.4236/ojd.2018.73004
Abstract: Introduction: Globally, the burden of depression is on the increase especially among women. The increased prevalence of depression correlates with hormonal changes in women, suggesting that female hormonal fluctuations may be a trigger for depression. Hence this study sought to determine the prevalence and socio-demographic pattern of depression among pre- and post-menopausal women. Methodology: A cross-sectional design comprising of pre- and post-menopausal women attending the General Outpatient Department of the Federal Medical Centre in Lokoja, North-Central region of Nigeria was employed in this study. Data on depression were collection using the Center for Epidemiologic Study Depression (CES-D) questionnaire, a validated and reliable tool for assessment of depression. Descriptive and inferential statistics were performed using Centers for Disease Control and Prevention (CDC) Epi Info version 7. Statistical significance was set at level of 0.05. Results: A total of 277 pre-menopausal and 103 post-menopausal women were involved in the study. The prevalence of depression was higher among post-menopausal women (45.6%) in comparison to pre-menopausal women (35.4%). There was no significant relationship between demographic characteristics and depression in both groups of the study (p > 0.05). Conclusion: This study noted that unlike the pre-menopausal population, almost half of the post-menopausal women had depression. Hence, routine screening for depression among post-menopausal women is advocated for timely intervention irrespective of their socio-demographic status.
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