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Search Results: 1 - 10 of 471438 matches for " IVAN A.; MONTOYA RESTREPO "
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Revista Facultad de Ciencias Económicas: Investigación y Reflexión , 2009,
Abstract: the present document examines some approaches about time conception associated to work on social sciences and on different scientific perspectives, mainly originated in the simplicity and order paradigm; the document starts by analyzing the subject, research through time and emergence of time concept since various approaches, in order to explore some implications in strategic management research. the document studies the development of simplicity paradigm from its mechanist version to identify that this approach conceives time as a given parameter. this work aims to show that the inclusion of consideration about the subject and the existence of internal observers in systems allow suggesting that time can be a variable that must be considered in social sciences and in studies about organization strategy.
Revista Facultad de Ciencias Económicas: Investigación y Reflexión , 2009,
Abstract: this review article is directed to acknowledge the main contributions relates to the manner how strategy is made and the cycles produced by its formation, paying particular attention to henry mintzberg's work. then, main aspects of the author are presented with habitual approaches and possible contribution it provides to the field.
Rese a de
Montoya de Restrepo, Lucía
Revista de Economía Institucional , 2001,
Propuesta de un Dise o Agroecológico para un Parque Natural Multifuncional (Finca Agualinda, Vereda Olarte en Usme, Bogotá D.C. - Colombia) Proposal of an Agroecologic Design for a Multifunctional Natural Park (Agualinda Farm, Olarte County, in Usme, Bogotá D.C. - Colombia)
Sandra Milena García Pe?a,Iván Alonso Montoya Restrepo,Luz Alexandra Montoya Restrepo
Revista Facultad Nacional de Agronomía, Medellín , 2012,
Abstract: Resumen. Las dificultades del bosque andino son de variada índole, por ello es necesario un estudio sistémico para solucionar problemas de tipo económico, social, político, tecnológico y ambiental en la región. Se muestran las potencialidades de la creación de un parque natural multifuncional (PNM), el cual se presenta como una oportunidad para la solución de las limitantes encontradas.La metodología seguida fue la aplicación del análisis PESTA, la matriz Vester, el procedimiento de impacto cruzado y la matriz IGO,de la cual resultan las variables que se califican. Con esta información se propone un árbol de problemas y de objetivos para un planteamiento de los escenarios posibles. La estrategia seleccionada consiste en una propuesta para el dise o de un PNM con especies endémicas colombianas de bosque altoandino y páramo. Se sustenta con la metodología seguida, el entendimiento de la problemática de la región y la identificación de las variables que deben impactarse para solucionarla. Abstract. This paper reveals the potential of creating a Multifunctional Natural Park (MNP). The difficulties of the Andean forest are of various kinds; for this reason, is needed to address a systematic study in order to propose answers to economic, social, political, technological and environmental affectations. The methodology was to apply PESTA analysis, priorization by application of Vester's matrix, the cross-impact procedure, and the importance and gobernability priorization of which results the variables that are scored. With this information is designed a tree of problems and objectives for a possible scenario useful for a subsequent selection of strategies. The choise way, is a proposal for sketch a MNP with endemic species, which is presented as an opportunity to solve the problems found. On the other hand, is sustained that the methodology employed is effective for understanding of region limitations and the identification of variables to be resolve.
El kibbutz desde el periodo pre-estatal (1945-1948) hasta finales del siglo XX
Montoya Restrepo,Iván A; Dávila Dávila,Celia;
Innovar , 2006,
Abstract: this article deals with the history of the kibbutz since the pre-state period (the time immediately before the state of israel was created) up to the final decades of the 20th century. it relates aspects in which the kibbutz placed a very important role, such as the economy, settlement, industrialisation, demographic and social development and intervention in politics and the defence of israel. this type of organisation has evolved within the framework of the arab-israeli conflict, a situation suffered by both nations for generations during the period being referred to. problems facing the kibbutz movement which almost finished with its existence are also considered, such as the economic crises, the incorporation of new members and immigrants, abandoning some aspects of kibbutz life. together with industrial and agricultural growth, the foregoing has led to contracted labour having had to be used. the ideological and structural changes originating from the kibbutz are presented. literary sources associated with a vision of an israeli world have been used for identifying new alternatives and strategies for adapting to such type of organisation.
Antecedentes y evolución del sistema de asentamiento y de los kibbutzim en Israel (1881-1944)
Montoya Restrepo,Iván A.; Dávila Dávila,Celia;
Innovar , 2005,
Abstract: a kibbutz is a unique phenomenon, seen as being a multi-generational community, providing a varied economic structure and great facility for adapting itself to the vicissitudes of both the israeli and world economy regarding globalisation and the competitiveness of products and services (near, 1992; simons & ingram, 2000). it has played a main role in israel?s history within the political, military and economic setting. the kibbutz movement boasts about being in the vanguard of the young socialist, labour-orientated jewish state (rotbart, 2000; ruffle & sosis, 2002; tsuk, 2000). the kibbutz became a fundamental and typical means of colonising palestine following the first world war in the eyes of the public (shafir, 1989). this article explores the situation of settlement in israel and the antecedents regarding how a kibbutz has been organised, trying to offer complete and systemic reflection on the topic. this investigation forms part of the bio-management research project into the kibbutz as an example of an organisation model.
Magnitud y distribución de diferentes formas de violencia en Medellín, 2003-2004
Duque,Luis Fernando; Montoya,Nilton Edu; Restrepo,María Vilma;
Revista Facultad Nacional de Salud Pública , 2006,
Abstract: objective: to estimate magnitude and distribution of being a victim, a witness or an aggressor in several types of violence in medellin, colombia. materials and methods: cross-sectional study in a representative sample (2,500) of individuals between 12 to 60 years old. data were collected through household interviews during the last months of 2003 and first trimester of 2004. results: men informed higher proportions of being victims, witnesses or aggressors than women, except for being a non armed aggressor, victim of forced displacement or sexual assault. victims per aggressor figure increases as violence is more severe. more than 75% of interviewees have witnessed severe threats and armed assault during their life time, around 40% reported being victims of severe threats, robbery and armed assault, and 6% reported being victims of sexual violence. highest victimization was reported by young people under 18 years old (legally minors). 10% of legally minors and 7% of individuals between 18 to 35 years old have committed robbery and 4% of those between 18 to 54 years old have committed armed assault. around 25% perceives that there are fights among neighbors or gangs and robberies in their own neighborhoods. probability of being an aggressor, victim or witness is estimated for each of the 16 medellin urban areas.
Detección molecular de Ralstonia solanacearum en agroecosistemas bananeros de Colombia
álvarez Restrepo, John A.;Rodríguez Gaviria, Paola A.;Marín Montoya, Mauricio;
Tropical Plant Pathology , 2008, DOI: 10.1590/S1982-56762008000300004
Abstract: moko disease of banana caused by ralstonia solanacearum is one of the most limiting factors in the production of this crop in the world. an alternative to reduce the incidence of this disease consists in the early detection of affected plants and soils with high levels of bacterial inoculum. this research evaluated different methods of nucleic acids extraction from plant material and soils, to be used in molecular diagnosis of r. solanacearum in the banana-growing region of urabá, colombia. results showed that for diagnosis of plant material, dna extraction should be done with commercial kits including silica gel columns or alternatively conventional methods using buffers containing pvpp. for bacterial detection from soil samples the most appropriated method was the microbial enrichment in smsa broth medium before dna extraction. multiplex pcr analysis indicated that phylotype ii, sequevar 4 was the causal agent of moko disease of banana in the region of urabá. techniques applied in this research could be used in epidemiological studies as well as to support management strategies of this disease in banana plantations.
The Autoimmune Tautology: An In Silico Approach
Ricardo A. Cifuentes,Daniel Restrepo-Montoya,Juan-Manuel Anaya
Autoimmune Diseases , 2012, DOI: 10.1155/2012/792106
Abstract: There is genetic evidence of similarities and differences among autoimmune diseases (AIDs) that warrants looking at a general panorama of what has been published. Thus, our aim was to determine the main shared genes and to what extent they contribute to building clusters of AIDs. We combined a text-mining approach to build clusters of genetic concept profiles (GCPs) from the literature in MedLine with knowledge of protein-protein interactions to confirm if genes in GCP encode proteins that truly interact. We found three clusters in which the genes with the highest contribution encoded proteins that showed strong and specific interactions. After projecting the AIDs on a plane, two clusters could be discerned: Sj?gren’s syndrome—systemic lupus erythematosus, and autoimmune thyroid disease—type1 diabetes—rheumatoid arthritis. Our results support the common origin of AIDs and the role of genes involved in apoptosis such as CTLA4, FASLG, and IL10. 1. Introduction There are clinical and genetic grounds for assuming similar immunogenetic mechanisms in autoimmune diseases (AIDs). Clinical evidence highlights the cooccurrence of distinct AIDs within members of a nuclear family and within an individual [1]. Individuals with a multiple autoimmune syndrome (MAS) have been grouped into three basic groups in which various AIDs cluster around one of three “main” AIDs, namely, systemic lupus erythematosus (SLE), autoimmune thyroid disease (AITD), and primary Sj?gren’s syndrome (SS). These three might be considered the “chaperones” of the other AID [2]. Along the same line of clinical evidence, there are therapies such as tumor necrosis factor inhibitors, rituximab, or a gluten-free diet that are already proving effective for more than one AID [3, 4]. With regards to genetic evidence, it has also been stated that around 44% of the single nucleotide polymorphisms (SNPs), which were found in genome-wide association studies (GWAS) on AIDs, are shared by two or more of the following diseases: celiac disease, Crohn’s disease, psoriasis, multiple sclerosis (MS), rheumatoid arthritis (RA), type 1 diabetes (T1D), and SLE [5]. There are also genetic differences among AIDs. In spite of sharing several susceptibility genes, the differences among most AIDs, in particular systemic ones such as SLE and RA, seem to reside in the contribution of each gene to each disease [6]. Additionally, clusters of AIDs have been described where SNPs that make an individual susceptible to one class of AIDs also protect from another class of AIDs [7]. Furthermore, it is already known that different
NClassG+: A classifier for non-classically secreted Gram-positive bacterial proteins
Daniel Restrepo-Montoya, Camilo Pino, Luis F Nino, Manuel E Patarroyo, Manuel A Patarroyo
BMC Bioinformatics , 2011, DOI: 10.1186/1471-2105-12-21
Abstract: Several feature-based classifiers were trained using different sequence transformation vectors (frequencies, dipeptides, physicochemical factors and PSSM) and Support Vector Machines (SVMs) with Linear, Polynomial and Gaussian kernel functions. Nested k-fold cross-validation (CV) was applied to select the best models, using the inner CV loop to tune the model parameters and the outer CV group to compute the error. The parameters and Kernel functions and the combinations between all possible feature vectors were optimized using grid search.The final model was tested against an independent set not previously seen by the model, obtaining better predictive performance compared to SecretomeP V2.0 and SecretPV2.0 for the identification of non-classically secreted proteins. NClassG+ is freely available on the web at http://www.biolisi.unal.edu.co/web-servers/nclassgpositive/ webciteMachine Learning (ML) tools have been successfully applied to the solution of a variety of biological problems such as the classification of proteins according to their subcellular localization and secretion mechanism. Different computational methods have been used to obtain reliable subcellular localization predictions, such as Artificial Neural Networks (ANNs), Hidden Markov Models (HMMs) and Support Vector Machines (SVM) [1-4].The simplest way of addressing classification problems is to follow a binary approach, trying to discriminate objects according to two categories: positive (+) and negative (-). SVMs rely on two concepts in order to solve this type of problems: the first one is known as the large-margin separation principle, which is motivated by the idea of classifying points in two dimensions; and the second one is known as Kernel methods [5].The Kernel methods that have been applied to bioinformatics are classified into three categories mainly: Kernels for real-valued data, Kernels for sequences and Kernels developed for specific purposes such as the Position-Specific Scoring Matrix
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